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PDB: 282 results
3S1Q
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BU of 3s1q by Molmil
RNA Polymerase II Initiation Complex with a 5-nt 3'-deoxy RNA soaked with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D.
Deposit date:2011-05-16
Release date:2011-08-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Initiation complex structure and promoter proofreading.
Science, 333, 2011
3S17
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BU of 3s17 by Molmil
RNA Polymerase II Initiation Complex with a 9-nt RNA
Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D.
Deposit date:2011-05-14
Release date:2011-08-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Initiation complex structure and promoter proofreading.
Science, 333, 2011
3S15
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BU of 3s15 by Molmil
RNA Polymerase II Initiation Complex with a 7-nt RNA
Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D.
Deposit date:2011-05-14
Release date:2011-08-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Initiation complex structure and promoter proofreading.
Science, 333, 2011
3S2H
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BU of 3s2h by Molmil
RNA Polymerase II Initiation Complex with a 6-nt RNA containing a 2[prime]-iodo ATP
Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D.
Deposit date:2011-05-16
Release date:2011-08-17
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Initiation complex structure and promoter proofreading.
Science, 333, 2011
3S1M
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BU of 3s1m by Molmil
RNA Polymerase II Initiation Complex with a 5-nt RNA (variant 1)
Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*GP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D.
Deposit date:2011-05-15
Release date:2011-08-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.13 Å)
Cite:Initiation complex structure and promoter proofreading.
Science, 333, 2011
3GTL
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BU of 3gtl by Molmil
Backtracked RNA polymerase II complex with 13mer with G<>U mismatch
Descriptor: DNA (28-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Wang, D, Bushnell, D.A, Huang, X, Westover, K.D, Levitt, M, Kornberg, R.D.
Deposit date:2009-03-27
Release date:2009-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.38 Å)
Cite:Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
Science, 324, 2009
3GTK
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BU of 3gtk by Molmil
Backtracked RNA polymerase II complex with 18mer RNA
Descriptor: DNA (29-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Wang, D, Bushnell, D.A, Huang, X, Westover, K.D, Levitt, M, Kornberg, R.D.
Deposit date:2009-03-27
Release date:2009-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
Science, 324, 2009
3GTP
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BU of 3gtp by Molmil
Backtracked RNA polymerase II complex with 24mer RNA
Descriptor: DNA (28-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Wang, D, Bushnell, D.A, Huang, X, Westover, K.D, Levitt, M, Kornberg, R.D.
Deposit date:2009-03-27
Release date:2009-06-09
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
Science, 324, 2009
3GTM
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BU of 3gtm by Molmil
Co-complex of Backtracked RNA polymerase II with TFIIS
Descriptor: DNA (28-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Wang, D, Bushnell, D.A, Huang, X, Westover, K.D, Levitt, M, Kornberg, R.D.
Deposit date:2009-03-27
Release date:2009-06-09
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
Science, 324, 2009
3IZ3
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BU of 3iz3 by Molmil
CryoEM structure of cytoplasmic polyhedrosis virus
Descriptor: Structural protein VP1, Structural protein VP3, Viral structural protein 5
Authors:Cheng, L, Sun, J, Zhang, K, Mou, Z, Huang, X, Ji, G, Sun, F, Zhang, J, Zhu, P.
Deposit date:2010-09-14
Release date:2011-03-16
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Atomic model of a cypovirus built from cryo-EM structure provides insight into the mechanism of mRNA capping.
Proc.Natl.Acad.Sci.USA, 108, 2011
3GTG
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BU of 3gtg by Molmil
Backtracked RNA polymerase II complex with 12mer RNA
Descriptor: DNA (28-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Wang, D, Bushnell, D.A, Huang, X, Westover, K.D, Levitt, M, Kornberg, R.D.
Deposit date:2009-03-27
Release date:2009-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.78 Å)
Cite:Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
Science, 324, 2009
3J6Q
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BU of 3j6q by Molmil
Identification of the active sites in the methyltransferases of a transcribing dsRNA virus
Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, Structural protein VP3
Authors:Zhu, B, Yang, C, Liu, H, Cheng, L, Song, F, Zeng, S, Huang, X, Ji, G, Zhu, P.
Deposit date:2014-03-20
Release date:2014-10-08
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Identification of the active sites in the methyltransferases of a transcribing dsRNA virus.
J.Mol.Biol., 426, 2014
3GTJ
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BU of 3gtj by Molmil
Backtracked RNA polymerase II complex with 13mer RNA
Descriptor: DNA (28-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Wang, D, Bushnell, D.A, Huang, X, Westover, K.D, Levitt, M, Kornberg, R.D.
Deposit date:2009-03-27
Release date:2009-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.42 Å)
Cite:Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
Science, 324, 2009
3GTO
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BU of 3gto by Molmil
Backtracked RNA polymerase II complex with 15mer RNA
Descriptor: DNA (28-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Wang, D, Bushnell, D.A, Huang, X, Westover, K.D, Levitt, M, Kornberg, R.D.
Deposit date:2009-03-27
Release date:2009-06-09
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
Science, 324, 2009
3GTQ
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BU of 3gtq by Molmil
Backtracked RNA polymerase II complex induced by damage
Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*CP*AP*TP*AP*AP*CP*CP*AP*CP*AP*GP*GP*CP*TP*CP*CP*TP*CP*TP*CP*CP*AP*TP*C)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Wang, D, Bushnell, D.A, Huang, X, Westover, K.D, Levitt, M, Kornberg, R.D.
Deposit date:2009-03-27
Release date:2009-06-09
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
Science, 324, 2009
3H5C
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BU of 3h5c by Molmil
X-Ray Structure of Protein Z-Protein Z Inhibitor Complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Protein Z-dependent protease inhibitor, Vitamin K-dependent protein Z, ...
Authors:Dementiev, A.A, Huang, X, Olson, S.T, Gettins, P.G.W.
Deposit date:2009-04-21
Release date:2010-04-28
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.26 Å)
Cite:Basis for the specificity and activation of the serpin protein Z-dependent proteinase inhibitor (ZPI) as an inhibitor of membrane-associated factor Xa.
J.Biol.Chem., 285, 2010
4NLH
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BU of 4nlh by Molmil
SKICH domain of human TAX1BP1
Descriptor: Tax1-binding protein 1
Authors:Yang, Y, Wang, G, Huang, X, Zhu, J, Du, Z.
Deposit date:2013-11-14
Release date:2014-12-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:SKICH domain of human TAX1BP1
To be published
5GNS
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BU of 5gns by Molmil
Structures of human Mitofusin 1 provide insight into mitochondrial tethering
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, Mitofusin-1
Authors:Qi, Y, Yan, L, Yu, C, Guo, X, Zhou, X, Hu, X, Huang, X, Rao, Z, Lou, Z, Hu, J.
Deposit date:2016-07-24
Release date:2016-12-07
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.702 Å)
Cite:Structures of human Mitofusin 1 provide insight into mitochondrial tethering
To Be Published
4OUH
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BU of 4ouh by Molmil
Crystal structure of the FP domain of Human PI31 Proteasome Inhibitor
Descriptor: Proteasome inhibitor PI31 subunit
Authors:Shang, J, Huang, X, Du, Z.
Deposit date:2014-02-17
Release date:2015-02-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:The FP domains of PI31 and Fbxo7 have the same protein fold but very different modes of protein-protein interaction.
J.Biomol.Struct.Dyn., 33, 2015
6BK4
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BU of 6bk4 by Molmil
Crystal structure of the HR-1 domain of Drosophila caprin in the P212121 space group
Descriptor: Caprin homolog
Authors:Zhu, J, Wu, Y, Huang, X, Du, Z.
Deposit date:2017-11-07
Release date:2018-11-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of a dimerization domain of Drosophila Caprin: further supports the assembly of an evolutionarily conserved ribonucleoprotein complex containing Caprin and FMRP
To Be Published
5VDI
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BU of 5vdi by Molmil
Crystal Structure of Human Glycine Receptor alpha-3 Mutant N38Q Bound to AM-3607, Glycine, and Ivermectin
Descriptor: (2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17 -oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacy clooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside, (3S,3aS,9bS)-2-[(2H-1,3-benzodioxol-5-yl)sulfonyl]-3,5-dimethyl-1,2,3,3a,5,9b-hexahydro-4H-pyrrolo[3,4-c][1,6]naphthyridin-4-one, GLYCINE, ...
Authors:Shaffer, P.L, Huang, X, Chen, H.
Deposit date:2017-04-03
Release date:2017-05-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal Structures of Human GlyR alpha 3 Bound to Ivermectin.
Structure, 25, 2017
3M3Y
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BU of 3m3y by Molmil
RNA polymerase II elongation complex C
Descriptor: DNA (28-MER), DNA (5'-D(*GP*TP*GP*GP*TP*TP*AP*TP*GP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Wang, D, Zhu, G, Huang, X, Lippard, S.J.
Deposit date:2010-03-10
Release date:2010-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.18 Å)
Cite:X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct.
Proc.Natl.Acad.Sci.USA, 107, 2010
6C45
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BU of 6c45 by Molmil
Crystal structure of human inorganic pyrophosphatase in the P212121 space group
Descriptor: Inorganic pyrophosphatase
Authors:Niu, H, Zhu, J, Huang, X, Du, Z.
Deposit date:2018-01-11
Release date:2019-01-16
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.388 Å)
Cite:Expression, purification and crystallization of the human protein PPA1
To be Published
5VDH
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BU of 5vdh by Molmil
Crystal Structure of Human Glycine Receptor alpha-3 Bound to AM-3607, Glycine, and Ivermectin
Descriptor: (2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17 -oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacy clooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside, (3S,3aS,9bS)-2-[(2H-1,3-benzodioxol-5-yl)sulfonyl]-3,5-dimethyl-1,2,3,3a,5,9b-hexahydro-4H-pyrrolo[3,4-c][1,6]naphthyridin-4-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Shaffer, P.L, Huang, X, Chen, H.
Deposit date:2017-04-03
Release date:2017-05-24
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal Structures of Human GlyR alpha 3 Bound to Ivermectin.
Structure, 25, 2017
5TIO
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BU of 5tio by Molmil
Crystal Structure of Human Glycine Receptor alpha-3 Bound to AM-3607
Descriptor: (3S,3aS,9bS)-2-[(2H-1,3-benzodioxol-5-yl)sulfonyl]-3,5-dimethyl-1,2,3,3a,5,9b-hexahydro-4H-pyrrolo[3,4-c][1,6]naphthyridin-4-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCINE, ...
Authors:Shaffer, P.L, Huang, X, Chen, H.
Deposit date:2016-10-03
Release date:2017-01-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Crystal Structures of Human GlyRa3 Bound to a Novel Class of Potentiators with Efficacy in a Mouse Model of Neuropathic Pain
To Be Published

226707

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