3LLZ
| Crystal Structure Analysis of Maclura pomifera agglutinin complex with Gal-beta-1,3-GalNAc | Descriptor: | Agglutinin alpha chain, Agglutinin beta-2 chain, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose | Authors: | Huang, J, Xu, Z, Wang, D, Ogato, C, Hirama, T, Palczewski, K, Hazen, S.L, Lee, X, Young, N.M. | Deposit date: | 2010-01-29 | Release date: | 2010-09-22 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Characterization of the secondary binding sites of Maclura pomifera agglutinin by glycan array and crystallographic analyses. Glycobiology, 20, 2010
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7MST
| Phosphorylated human E105Qa GTP-specific succinyl-CoA synthetase complexed with coenzyme A | Descriptor: | 1,2-ETHANEDIOL, COENZYME A, GLYCEROL, ... | Authors: | Huang, J, Fraser, M.E. | Deposit date: | 2021-05-12 | Release date: | 2022-10-12 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | The structure of succinyl-CoA synthetase bound to the succinyl-phosphate intermediate clarifies the catalytic mechanism of ATP-citrate lyase Acta Crystallogr.,Sect.F, 78, 2022
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7MSS
| Human E105Qa GTP-specific succinyl-CoA synthetase complexed with succinate, magnesium ion and CoA | Descriptor: | COENZYME A, GLYCEROL, MAGNESIUM ION, ... | Authors: | Huang, J, Fraser, M.E. | Deposit date: | 2021-05-12 | Release date: | 2022-10-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | The structure of succinyl-CoA synthetase bound to the succinyl-phosphate intermediate clarifies the catalytic mechanism of ATP-citrate lyase Acta Crystallogr.,Sect.F, 78, 2022
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7MSR
| Human E105Qa GTP-specific succinyl-CoA synthetase complexed with succinyl-phosphate, magnesium ion and desulfo-coenzyme A | Descriptor: | 1,2-ETHANEDIOL, 4-oxo-4-(phosphonooxy)butanoic acid, DESULFO-COENZYME A, ... | Authors: | Huang, J, Fraser, M.E. | Deposit date: | 2021-05-12 | Release date: | 2022-10-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | The structure of succinyl-CoA synthetase bound to the succinyl-phosphate intermediate clarifies the catalytic mechanism of ATP-citrate lyase Acta Crystallogr.,Sect.F, 78, 2022
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3U85
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4I80
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5GHE
| Crystal Structure of Bacillus thuringiensis Cry6Aa2 Protoxin | Descriptor: | Pesticidal crystal protein Cry6Aa | Authors: | Huang, J, Guan, Z, Zou, T, Sun, M, Yin, P. | Deposit date: | 2016-06-19 | Release date: | 2016-08-03 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.901 Å) | Cite: | Crystal structure of Cry6Aa: A novel nematicidal ClyA-type alpha-pore-forming toxin from Bacillus thuringiensis Biochem.Biophys.Res.Commun., 478, 2016
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3U84
| Crystal Structure of Human Menin | Descriptor: | Menin | Authors: | Huang, J, Wan, B, Lei, M. | Deposit date: | 2011-10-15 | Release date: | 2012-02-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The same pocket in menin binds both MLL and JUND but has opposite effects on transcription. Nature, 482, 2012
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3U86
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2QBW
| The crystal structure of PDZ-Fibronectin fusion protein | Descriptor: | PDZ-Fibronectin fusion protein, Polypeptide | Authors: | Huang, J, Makabe, K, Koide, A, Koide, S. | Deposit date: | 2007-06-18 | Release date: | 2008-04-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Design of protein function leaps by directed domain interface evolution. Proc.Natl.Acad.Sci.Usa, 105, 2008
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3U88
| Crystal structure of human menin in complex with MLL1 and LEDGF | Descriptor: | (4beta,8alpha,9R)-6'-methoxy-10,11-dihydrocinchonan-9-ol, CHOLIC ACID, GLYOXYLIC ACID, ... | Authors: | Huang, J, Wan, B, Lei, M. | Deposit date: | 2011-10-16 | Release date: | 2012-02-15 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The same pocket in menin binds both MLL and JUND but has opposite effects on transcription. Nature, 482, 2012
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6KIW
| Cryo-EM structure of human MLL3-ubNCP complex (4.0 angstrom) | Descriptor: | DNA (144-MER), DNA (145-MER), Histone H2A, ... | Authors: | Huang, J, Xue, H, Yao, T. | Deposit date: | 2019-07-20 | Release date: | 2019-09-11 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural basis of nucleosome recognition and modification by MLL methyltransferases. Nature, 573, 2019
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6LT7
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6NO3
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6NO6
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7JFP
| GTP-specific succinyl-CoA synthetase complexed with Mg-GDP, phosphohistidine loop pointing towards nucleotide binding site | Descriptor: | GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Huang, J, Fraser, M.E. | Deposit date: | 2020-07-17 | Release date: | 2021-03-10 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Second distinct conformation of the phosphohistidine loop in succinyl-CoA synthetase Acta Crystallogr.,Sect.D, 77, 2021
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7JJ0
| GTP-specific succinyl-CoA synthetase complexed with Mg-GMPPCP | Descriptor: | MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, ... | Authors: | Huang, J, Fraser, M.E. | Deposit date: | 2020-07-24 | Release date: | 2021-03-10 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Second distinct conformation of the phosphohistidine loop in succinyl-CoA synthetase Acta Crystallogr.,Sect.D, 77, 2021
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7JMK
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7JKR
| GTP-specific succinyl-CoA synthetase complexed with Mg-GMPPNP, phosphohistidine loop pointing towards nucleotide binding site | Descriptor: | GLYCEROL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Huang, J, Fraser, M.E. | Deposit date: | 2020-07-28 | Release date: | 2021-03-10 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | Second distinct conformation of the phosphohistidine loop in succinyl-CoA synthetase Acta Crystallogr.,Sect.D, 77, 2021
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7E85
| SnoaL-like domain-containing protein | Descriptor: | SnoaL-like domain-containing protein | Authors: | Zhuang, J. | Deposit date: | 2021-03-01 | Release date: | 2022-03-02 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.424 Å) | Cite: | SnoaL-like domain-containing protein To Be Published
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4U24
| Crystal structure of the E. coli ribosome bound to dalfopristin. | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Noeske, J, Huang, J, Olivier, N.B, Giacobbe, R.A, Zambrowski, M, Cate, J.H.D. | Deposit date: | 2014-07-16 | Release date: | 2014-07-30 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Synergy of streptogramin antibiotics occurs independently of their effects on translation. Antimicrob.Agents Chemother., 58, 2014
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4U1U
| Crystal structure of the E. coli ribosome bound to quinupristin. | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Noeske, J, Huang, J, Olivier, N.B, Giacobbe, R.A, Zambrowski, M, Cate, J.H.D. | Deposit date: | 2014-07-16 | Release date: | 2014-07-30 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Synergy of streptogramin antibiotics occurs independently of their effects on translation. Antimicrob.Agents Chemother., 58, 2014
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4U26
| Crystal structure of the E. coli ribosome bound to dalfopristin and quinupristin. | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Noeske, J, Huang, J, Olivier, N.B, Giacobbe, R.A, Zambrowski, M, Cate, J.H.D. | Deposit date: | 2014-07-16 | Release date: | 2014-07-30 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Synergy of streptogramin antibiotics occurs independently of their effects on translation. Antimicrob.Agents Chemother., 58, 2014
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4WF1
| Crystal structure of the E. coli ribosome bound to negamycin. | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Olivier, N.B, Altman, R.B, Noeske, J, Basarab, G.S, Code, E, Ferguson, A.D, Gao, N, Huang, J, Juette, M.F, Livchak, S, Miller, M.D, Prince, D.B, Cate, J.H.D, Buurman, E.T, Blanchard, S.C. | Deposit date: | 2014-09-11 | Release date: | 2014-11-05 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (3.09 Å) | Cite: | Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the Escherichia coli ribosome. Proc.Natl.Acad.Sci.USA, 111, 2014
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7S0F
| Isoproterenol bound beta1 adrenergic receptor in complex with heterotrimeric Gi protein | Descriptor: | Beta1-Adrenergic Receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Paknejad, N, Alegre, K.O, Su, M, Lou, J.S, Huang, J, Jordan, K.D, Eng, E.T, Meyerson, J.R, Hite, R.K, Huang, X.Y. | Deposit date: | 2021-08-30 | Release date: | 2021-11-17 | Last modified: | 2021-12-01 | Method: | ELECTRON MICROSCOPY (2.96 Å) | Cite: | Structural basis and mechanism of activation of two different families of G proteins by the same GPCR. Nat.Struct.Mol.Biol., 28, 2021
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