1NMJ
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5HIN
| Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 18L compound | 分子名称: | ACETATE ION, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... | 著者 | Huang, J, Wu, D, Lu, Q, Yao, X. | 登録日 | 2016-01-12 | 公開日 | 2016-07-20 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 18L at 1.60 A resolution To Be Published
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5HQE
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4AGH
| Structural features of ssDNA binding protein MoSub1 from Magnaporthe oryzae | 分子名称: | MOSUB1, TRANSCRIPTION COFACTOR | 著者 | Huang, J, Zhao, Y, Huang, D, liu, J, Peng, Y. | 登録日 | 2012-01-27 | 公開日 | 2012-08-29 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.787 Å) | 主引用文献 | Structural Features of the Single-Stranded DNA-Binding Protein Mosub1 from Magnaporthe Oryzae. Acta Crystallogr.,Sect.D, 68, 2012
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4BHM
| The crystal structure of MoSub1-DNA complex reveals a novel DNA binding mode | 分子名称: | 5'-D(*TP*TP*TP*TP*TP*TP*TP*TP)-3', MOSUB1 TRANSCRIPTION COFACTOR, SULFATE ION | 著者 | Huang, J, Liu, H, Zhao, Y, Huang, D, liu, J, Peng, Y. | 登録日 | 2013-04-04 | 公開日 | 2014-04-23 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Substitution of Tryptophan 89 with Tyrosine Switches the DNA Binding Mode of Pc4. Sci.Rep., 5, 2015
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3LLZ
| Crystal Structure Analysis of Maclura pomifera agglutinin complex with Gal-beta-1,3-GalNAc | 分子名称: | Agglutinin alpha chain, Agglutinin beta-2 chain, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose | 著者 | Huang, J, Xu, Z, Wang, D, Ogato, C, Hirama, T, Palczewski, K, Hazen, S.L, Lee, X, Young, N.M. | 登録日 | 2010-01-29 | 公開日 | 2010-09-22 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Characterization of the secondary binding sites of Maclura pomifera agglutinin by glycan array and crystallographic analyses. Glycobiology, 20, 2010
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3LLY
| Crystal Structure Analysis of Maclura pomifera agglutinin | 分子名称: | Agglutinin alpha chain, Agglutinin beta-2 chain | 著者 | Huang, J, Xu, Z, Wang, D, Ogato, C, Hirama, T, Palczewski, K, Hazen, S.L, Lee, X, Young, N.M. | 登録日 | 2010-01-29 | 公開日 | 2010-09-22 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Characterization of the secondary binding sites of Maclura pomifera agglutinin by glycan array and crystallographic analyses. Glycobiology, 20, 2010
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8T1R
| Crystal structure of human CPSF73 catalytic segment in complex with compound 2 | 分子名称: | 3-[7,7-bis(oxidanyl)-8-oxa-7-boranuidabicyclo[4.3.0]nona-1,3,5-trien-5-yl]-~{N}-[3-(3-methoxyphenyl)phenyl]propanamide, CHLORIDE ION, Cleavage and polyadenylation specificity factor subunit 3, ... | 著者 | Huang, J, Tong, L. | 登録日 | 2023-06-02 | 公開日 | 2023-11-08 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Anticancer benzoxaboroles block pre-mRNA processing by directly inhibiting CPSF3. Cell Chem Biol, 31, 2024
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8T1Q
| Crystal structure of human CPSF73 catalytic segment in complex with compound 1 | 分子名称: | 3-[7,7-bis(oxidanyl)-8-oxa-7-boranuidabicyclo[4.3.0]nona-1,3,5-trien-5-yl]-~{N}-[3-(4-ethanoylphenyl)phenyl]propanamide, CHLORIDE ION, Cleavage and polyadenylation specificity factor subunit 3, ... | 著者 | Huang, J, Tong, L. | 登録日 | 2023-06-02 | 公開日 | 2023-11-08 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Anticancer benzoxaboroles block pre-mRNA processing by directly inhibiting CPSF3. Cell Chem Biol, 31, 2024
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8JB4
| lipopolysaccharide-binding domain-LBDB | 分子名称: | Antilipopolysaccharide factor D | 著者 | Huang, J, Qin, Z. | 登録日 | 2023-05-08 | 公開日 | 2024-03-13 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Machine learning and genetic algorithm-guided directed evolution for the development of small-molecule antibiotics originating from antimicrobial peptides To Be Published
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6EE7
| Small tetraheme cytochrome c from Shewanella oneidensis | 分子名称: | HEME C, Periplasmic tetraheme cytochrome c CctA, ZINC ION | 著者 | Huang, J, Zarzycki, J, Ducat, D.C, Kramer, D.M. | 登録日 | 2018-08-13 | 公開日 | 2019-08-14 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.394 Å) | 主引用文献 | Mesoscopic to Macroscopic Electron Transfer by Hopping in a Crystal Network of Cytochromes. J.Am.Chem.Soc., 142, 2020
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6W16
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6WCV
| Tartryl-CoA bound to human GTP-specific succinyl-CoA synthetase | 分子名称: | (3S,5S,9R,20R,21R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9,20, 21-pentahydroxy-8,8-dimethyl-10,14,19-trioxo-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphadocosan-22-oic acid 3,5-dioxide (non-preferred name), Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, ... | 著者 | Huang, J, Fraser, M.E. | 登録日 | 2020-03-31 | 公開日 | 2020-07-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | Tartryl-CoA inhibits succinyl-CoA synthetase Acta Crystallogr.,Sect.F, 76, 2020
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8H7G
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6XRU
| GTP-specific succinyl-CoA synthetase complexed with desulfo-coenzyme A, magnesium ions and succinates | 分子名称: | 1,2-ETHANEDIOL, DESULFO-COENZYME A, GLYCEROL, ... | 著者 | Huang, J, Fraser, M.E. | 登録日 | 2020-07-13 | 公開日 | 2021-03-10 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Second distinct conformation of the phosphohistidine loop in succinyl-CoA synthetase Acta Crystallogr.,Sect.D, 77, 2021
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5BPP
| Structure of human Leukotriene A4 hydrolase in complex with inhibitor 4AZ | 分子名称: | 2-(4-butoxyphenyl)-N-hydroxyacetamide, ACETATE ION, Leukotriene A-4 hydrolase, ... | 著者 | Huang, J, Dong, N.N, Xiao, Q, Ou, P.Y, Wu, D, Lu, W.Q. | 登録日 | 2015-05-28 | 公開日 | 2016-08-10 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Bufexamac ameliorates LPS-induced acute lung injury in mice by targeting LTA4H Sci Rep, 6, 2016
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8EJM
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4ZL1
| Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 18X at 1.86 A resolution | 分子名称: | Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ... | 著者 | Huang, J, Wu, D, Ouyang, P, Lu, W, Pu, J. | 登録日 | 2015-05-01 | 公開日 | 2016-05-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 18XYW at 1.86 A resolution To Be Published
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2AIR
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8E15
| A computationally stabilized hMPV F protein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, F1 protein with Fibritin peptide, F2 protein, ... | 著者 | Huang, J, Gonzalez, K, Mousa, J, Strauch, E. | 登録日 | 2022-08-09 | 公開日 | 2023-04-12 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | A general computational design strategy for stabilizing viral class I fusion proteins. Nat Commun, 15, 2024
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1Q95
| Aspartate Transcarbamylase (ATCase) of Escherichia coli: A New Crystalline R State Bound to PALA, or to Product Analogues Phosphate and Citrate | 分子名称: | Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, ... | 著者 | Huang, J, Lipscomb, W.N. | 登録日 | 2003-08-22 | 公開日 | 2004-06-08 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | Aspartate Transcarbamylase (ATCase) of Escherichia coli: A New Crystalline R-State Bound to PALA, or to Product Analogues Citrate and Phosphate Biochemistry, 43, 2004
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1R0C
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1R0B
| Aspartate Transcarbamylase (ATCase) of Escherichia coli: A New Crystalline R State Bound to PALA, or to Product Analogues Phosphate and Citrate | 分子名称: | Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, CITRATE ANION, ... | 著者 | Huang, J, Lipscomb, W.N. | 登録日 | 2003-09-19 | 公開日 | 2004-06-08 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Aspartate Transcarbamylase (ATCase) of Escherichia coli: A New Crystalline R-State Bound to PALA, or to Product Analogues Citrate and Phosphate Biochemistry, 43, 2004
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6NO3
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6NO6
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