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PDB: 122 件

8HFD
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Crystal structure of allantoinase from E. coli BL21
分子名称: Allantoinase, DI(HYDROXYETHYL)ETHER, ZINC ION
著者Lin, E.S, Huang, H.Y, Yang, P.C, Liu, H.W, Huang, C.Y.
登録日2022-11-10
公開日2023-10-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Crystal Structure of Allantoinase from Escherichia coli BL21: A Molecular Insight into a Role of the Active Site Loops in Catalysis.
Molecules, 28, 2023
8GW0
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Crystal structure of the human dihydroorotase domain in complex with malic acid
分子名称: (2S)-2-hydroxybutanedioic acid, CAD protein, ZINC ION
著者Yang, P.C, Liu, H.W, Huang, H.Y, Huang, C.Y.
登録日2022-09-16
公開日2023-09-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Complexed Crystal Structure of the Dihydroorotase Domain of Human CAD Protein with the Anticancer Drug 5-Fluorouracil.
Biomolecules, 13, 2023
8GW5
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Crystal structure of SaSsbA complexed with glycerol
分子名称: GLYCEROL, Single-stranded DNA-binding protein
著者Yang, P.C, Huang, H.Y, Huang, C.Y.
登録日2022-09-16
公開日2023-09-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of DNA Replication Protein SsbA Complexed with the Anticancer Drug 5-Fluorouracil.
Int J Mol Sci, 24, 2023
8GVZ
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Crystal structure of the human dihydroorotase domain in complex with the anticancer drug 5-fluorouracil
分子名称: 5-FLUOROURACIL, CAD protein, ZINC ION
著者Liu, H.W, Yang, P.C, Huang, H.Y, Huang, C.Y.
登録日2022-09-16
公開日2023-09-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Complexed Crystal Structure of the Dihydroorotase Domain of Human CAD Protein with the Anticancer Drug 5-Fluorouracil.
Biomolecules, 13, 2023
2Q7Z
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Solution Structure of the 30 SCR domains of human Complement Receptor 1
分子名称: Complement receptor type 1
著者Furtado, P.B, Huang, C.Y, Ihyembe, D, Hammond, R.A, Marsh, H.C, Perkins, S.J.
登録日2007-06-08
公開日2007-10-16
最終更新日2024-02-21
実験手法SOLUTION SCATTERING
主引用文献The Partly Folded Back Solution Structure Arrangement of the 30 SCR Domains in Human Complement Receptor Type 1 (CR1) Permits Access to its C3b and C4b Ligands
J.Mol.Biol., 375, 2008
5V54
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Crystal structure of 5-HT1B receptor in complex with methiothepin
分子名称: 1-methyl-4-[(5~{S})-3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl]piperazine, 5-hydroxytryptamine receptor 1B,OB-1 fused 5-HT1b receptor,5-hydroxytryptamine receptor 1B
著者Yin, W.C, Zhou, X.E, Yang, D, de Waal, P, Wang, M.T, Dai, A, Cai, X, Huang, C.Y, Liu, P, Yin, Y, Liu, B, Caffrey, M, Melcher, K, Xu, Y, Wang, M.W, Xu, H.E, Jiang, Y.
登録日2017-03-13
公開日2018-02-07
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献A common antagonistic mechanism for class A GPCRs revealed by the structure of the human 5-HT1B serotonin receptor bound to an antagonist
Cell Discov, 2018
4XNL
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X-ray structure of AlgE2
分子名称: (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, ...
著者Ma, P, Huang, C.Y, Olieric, V, Diederichs, K, Wang, M, Caffrey, M.
登録日2015-01-15
公開日2015-06-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献In meso in situ serial X-ray crystallography of soluble and membrane proteins.
Acta Crystallogr.,Sect.D, 71, 2015
4XNK
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X-ray structure of AlgE1
分子名称: (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Alginate production protein AlgE, ...
著者Ma, P, Huang, C.Y, Olieric, V, Diederichs, K, Wang, M, Caffrey, M.
登録日2015-01-15
公開日2015-06-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献In meso in situ serial X-ray crystallography of soluble and membrane proteins.
Acta Crystallogr.,Sect.D, 71, 2015
7CA0
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Crystal structure of dihydroorotase in complex with 5-fluoroorotic acid from Saccharomyces cerevisiae
分子名称: 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, ZINC ION
著者Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J.
登録日2020-06-08
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Complexed Crystal Structure of Saccharomyces cerevisiae Dihydroorotase with Inhibitor 5-Fluoroorotate Reveals a New Binding Mode.
Bioinorg Chem Appl, 2021, 2021
7CA1
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Crystal structure of dihydroorotase in complex with plumbagin from Saccharomyces cerevisiae
分子名称: (2S)-2-hydroxybutanedioic acid, 5-hydroxy-2-methylnaphthalene-1,4-dione, Dihydroorotase, ...
著者Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J.
登録日2020-06-08
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Plumbagin, a Natural Product with Potent Anticancer Activities, Binds to and Inhibits Dihydroorotase, a Key Enzyme in Pyrimidine Biosynthesis.
Int J Mol Sci, 22, 2021
7L1E
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The Crystal Structure of Bromide-Bound GtACR1
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Anion channelrhodopsin-1, BROMIDE ION, ...
著者Li, H, Huang, C.Y, Wang, M, Spudich, J.L, Zheng, L.
登録日2020-12-14
公開日2021-05-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The crystal structure of bromide-bound Gt ACR1 reveals a pre-activated state in the transmembrane anion tunnel.
Elife, 10, 2021
7DEP
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S. aureus SsbB with 5-FU
分子名称: 5-FLUOROURACIL, Single-stranded DNA-binding protein
著者Lin, E.S, Huang, Y.H, Huang, C.Y.
登録日2020-11-04
公開日2020-12-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.094 Å)
主引用文献Crystal structure of the single-stranded DNA-binding protein SsbB in complex with the anticancer drug 5-fluorouracil: Extension of the 5-fluorouracil interactome to include the oligonucleotide/oligosaccharide-binding fold protein
Biochem.Biophys.Res.Commun., 534, 2020
7AC4
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Structure of insulin collected by rotation serial crystallography on a COC membrane at a synchrotron source
分子名称: Insulin, R-1,2-PROPANEDIOL, SODIUM ION
著者Martiel, I, Padeste, C, Karpik, A, Huang, C.Y, Vera, L, Wang, M, Marsh, M.
登録日2020-09-09
公開日2021-09-01
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Versatile microporous polymer-based supports for serial macromolecular crystallography.
Acta Crystallogr D Struct Biol, 77, 2021
7AC2
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Structure of Hen Egg White Lysozyme collected by rotation serial crystallography on a COC membrane at a synchrotron source
分子名称: CHLORIDE ION, Lysozyme, SODIUM ION
著者Martiel, I, Padeste, C, Karpik, A, Huang, C.Y, Vera, L, Wang, M, Marsh, M.
登録日2020-09-09
公開日2021-09-01
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.507 Å)
主引用文献Versatile microporous polymer-based supports for serial macromolecular crystallography.
Acta Crystallogr D Struct Biol, 77, 2021
7AC3
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Structure of thaumatin collected by rotation serial crystallography on a COC membrane at a synchrotron source
分子名称: L(+)-TARTARIC ACID, S-1,2-PROPANEDIOL, SODIUM ION, ...
著者Martiel, I, Padeste, C, Karpik, A, Huang, C.Y, Vera, L, Wang, M, Marsh, M.
登録日2020-09-09
公開日2021-09-01
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Versatile microporous polymer-based supports for serial macromolecular crystallography.
Acta Crystallogr D Struct Biol, 77, 2021
7AC6
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Structure of sponge-phase grown PepTst2 collected by rotation serial crystallography on a COC membrane at a synchrotron source
分子名称: (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, 2-(2-METHOXYETHOXY)ETHANOL, Di-or tripeptide:H+ symporter, ...
著者Martiel, I, Padeste, C, Karpik, A, Huang, C.Y, Wang, M, Marsh, M.
登録日2020-09-10
公開日2021-09-01
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Versatile microporous polymer-based supports for serial macromolecular crystallography.
Acta Crystallogr D Struct Biol, 77, 2021
7AC5
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Structure of Tubulin Darpin complex 1 collected by rotation serial crystallography on a COC membrane at a synchrotron source
分子名称: 2-(2-METHOXYETHOXY)ETHANOL, Designed Ankyrin Repeat Protein (DARPIN) D1, GUANOSINE-5'-DIPHOSPHATE, ...
著者Martiel, I, Olieric, N, Wranik, M, Padeste, C, Karpik, A, Huang, C.Y, Wang, M, Marsh, M.
登録日2020-09-10
公開日2021-09-01
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Versatile microporous polymer-based supports for serial macromolecular crystallography.
Acta Crystallogr D Struct Biol, 77, 2021
7AI8
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Structure of Ribonucleotide reductase R2 from Escherichia coli collected by still serial crystallography on a COC membrane at a synchrotron source
分子名称: FE (III) ION, Ribonucleoside-diphosphate reductase 1 subunit beta
著者Aurelius, O, John, J, Martiel, I, Padeste, C, Karpik, A, Huang, C.Y, Hogbom, M, Wang, M, Marsh, M.
登録日2020-09-26
公開日2021-09-01
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Versatile microporous polymer-based supports for serial macromolecular crystallography.
Acta Crystallogr D Struct Biol, 77, 2021
7AI9
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Structure of Ribonucleotide reductase R2 from Escherichia coli collected by rotation serial crystallography on a COC membrane at a synchrotron source
分子名称: FE (III) ION, Ribonucleoside-diphosphate reductase 1 subunit beta
著者Aurelius, O, John, J, Martiel, I, Padeste, C, Karpik, A, Huang, C.Y, Hogbom, M, Wang, M, Marsh, M.
登録日2020-09-26
公開日2021-09-01
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Versatile microporous polymer-based supports for serial macromolecular crystallography.
Acta Crystallogr D Struct Biol, 77, 2021
5YYU
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Crystal structure of Staphylococcus aureus single-stranded DNA-binding protein SsbB
分子名称: Single-stranded DNA-binding protein
著者Huang, Y.H, Huang, C.Y.
登録日2017-12-11
公開日2018-08-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.984 Å)
主引用文献Characterization of single-stranded DNA-binding protein SsbB from Staphylococcus aureus: SsbB cannot stimulate PriA helicase.
Rsc Adv, 8, 2018
7F2N
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Crystal structure of SSB from Klebsiella pneumonia.
分子名称: Single-stranded DNA-binding protein
著者Lin, E.S, Huang, Y.H, Huang, C.Y.
登録日2021-06-11
公開日2021-11-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Characterization of the Chimeric PriB-SSBc Protein.
Int J Mol Sci, 22, 2021
7F25
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Crystal structure of SSB from Salmonella enterica serovar Typhimurium LT2.
分子名称: Single-stranded DNA-binding protein 1
著者Luo, R.H, Huang, Y.H, Huang, C.Y.
登録日2021-06-10
公開日2022-05-04
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.87 Å)
主引用文献Crystal Structure of an SSB Protein from Salmonella enterica and Its Inhibition by Flavanonol Taxifolin.
Int J Mol Sci, 23, 2022
5YKD
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Crystal structure of dihydropyrimidinase from Pseudomonas aeruginosa PAO1 at 2.17 angstrom resolution
分子名称: D-hydantoinase/dihydropyrimidinase, ZINC ION
著者Huang, Y.H, Huang, C.Y.
登録日2017-10-14
公開日2018-02-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structural Basis for pH-Dependent Oligomerization of Dihydropyrimidinase fromPseudomonas aeruginosaPAO1.
Bioinorg Chem Appl, 2018, 2018
6I59
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Long wavelength native-SAD phasing of Sen1 helicase
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ...
著者Basu, S, Olieric, V, Matsugaki, N, Kawano, Y, Takashi, T, Huang, C.Y, Leonarski, F, Yamada, Y, Vera, L, Olieric, N, Basquin, J, Wojdyla, J.A, Diederichs, K, Yamamoto, M, Bunk, O, Wang, M.
登録日2018-11-13
公開日2019-03-13
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Long-wavelength native-SAD phasing: opportunities and challenges.
Iucrj, 6, 2019
5XGT
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Crystal structure of the N-terminal domain of Staphylococcus aureus single-stranded DNA-binding protein SsbA at 1.82 angstrom resolution
分子名称: GLYCEROL, Single-stranded DNA-binding protein
著者Huang, Y.H, Chen, C.J, Huang, C.Y.
登録日2017-04-17
公開日2017-08-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Staphylococcus aureus single-stranded DNA-binding protein SsbA can bind but cannot stimulate PriA helicase.
PLoS ONE, 12, 2017

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件を2024-07-17に公開中

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