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PDB: 180 件

8FNC
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Cryo-EM structure of RNase-treated RESC-C in trypanosomal RNA editing
分子名称: Mitochondrial RNA binding complex 1 subunit, Mitochondrial RNA binding protein, Phytanoyl-CoA dioxygenase family protein, ...
著者Liu, S, Wang, H, Li, X, Zhang, F, Lee, J.K.J, Li, Z, Yu, C, Zhao, X, Hu, J.J, Suematsu, T, Alvarez-Cabrera, A.L, Liu, Q, Zhang, L, Huang, L, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H.
登録日2022-12-27
公開日2023-07-19
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing.
Science, 381, 2023
8FN4
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BU of 8fn4 by Molmil
Cryo-EM structure of RNase-treated RESC-A in trypanosomal RNA editing
分子名称: RNA-editing substrate-binding complex protein 1 (RESC1), RNA-editing substrate-binding complex protein 2 (RESC2), RNA-editing substrate-binding complex protein 3 (RESC3), ...
著者Liu, S, Wang, H, Li, X, Zhang, F, Lee, J.K.J, Li, Z, Yu, C, Zhao, X, Hu, J.J, Suematsu, T, Alvarez-Cabrera, A.L, Liu, Q, Zhang, L, Huang, L, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H.
登録日2022-12-26
公開日2023-07-19
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing.
Science, 381, 2023
8FNF
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Cryo-EM structure of RNase-untreated RESC-C in trypanosomal RNA editing
分子名称: Mitochondrial RNA binding complex 1 subunit, Mitochondrial RNA binding protein, Phytanoyl-CoA dioxygenase family protein, ...
著者Liu, S, Wang, H, Li, X, Zhang, F, Lee, J.K.J, Li, Z, Yu, C, Zhao, X, Hu, J.J, Suematsu, T, Alvarez-Cabrera, A.L, Liu, Q, Zhang, L, Huang, L, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H.
登録日2022-12-27
公開日2023-07-19
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing.
Science, 381, 2023
8FN6
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BU of 8fn6 by Molmil
Cryo-EM structure of RNase-untreated RESC-A in trypanosomal RNA editing
分子名称: ADENOSINE-5'-TRIPHOSPHATE, RNA-editing substrate-binding complex protein 1 (RESC1), RNA-editing substrate-binding complex protein 2 (RESC2), ...
著者Liu, S, Wang, H, Li, X, Zhang, F, Lee, J.K.J, Li, Z, Yu, C, Zhao, X, Hu, J.J, Suematsu, T, Alvarez-Cabrera, A.L, Liu, Q, Zhang, L, Huang, L, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H.
登録日2022-12-27
公開日2023-07-19
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing.
Science, 381, 2023
2JZO
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BU of 2jzo by Molmil
Solution NMR structure of the non-productive complex between IIAMannose and IIBMannose of the mannose transporter of the E. coli phosphotransferase system
分子名称: PTS system mannose-specific EIIAB component
著者Clore, G, Hu, J, Hu, K.
登録日2008-01-10
公開日2008-02-19
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Solution NMR Structures of Productive and Non-productive Complexes between the A and B Domains of the Cytoplasmic Subunit of the Mannose Transporter of the Escherichia coli Phosphotransferase System.
J.Biol.Chem., 283, 2008
2JZN
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BU of 2jzn by Molmil
Solution NMR structure of the productive complex between IIAMannose and IIBMannose of the mannose transporter of the E. coli phosphotransferase system
分子名称: Mannose-specific phosphotransferase enzyme IIA component, Mannose-specific phosphotransferase enzyme IIB component
著者Clore, G.M, Hu, J, Hu, K.
登録日2008-01-10
公開日2008-02-19
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献Solution NMR Structures of Productive and Non-productive Complexes between the A and B Domains of the Cytoplasmic Subunit of the Mannose Transporter of the Escherichia coli Phosphotransferase System.
J.Biol.Chem., 283, 2008
6J72
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Crystal structure of IniA from Mycobacterium smegmatis with GTP bound
分子名称: GUANOSINE-5'-TRIPHOSPHATE, Isoniazid inducible gene protein IniA, L(+)-TARTARIC ACID, ...
著者Wang, M.F, Guo, X.Y, Hu, J.J, Li, J, Rao, Z.H.
登録日2019-01-16
公開日2019-09-11
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Mycobacterial dynamin-like protein IniA mediates membrane fission.
Nat Commun, 10, 2019
6J73
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Crystal structure of IniA from Mycobacterium smegmatis
分子名称: Isoniazid inducible gene protein IniA
著者Wang, M.F, Guo, X.Y, Hu, J.J, Li, J, Rao, Z.H.
登録日2019-01-16
公開日2019-09-11
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.211 Å)
主引用文献Mycobacterial dynamin-like protein IniA mediates membrane fission.
Nat Commun, 10, 2019
8EZF
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A tethered niacin-derived pincer complex with a nickel-carbon or sulfite-carbon bond in lactate racemase R98A/R100A variant
分子名称: (4S)-5-methanethioyl-1-(5-O-phosphono-beta-D-ribofuranosyl)-4-sulfo-1,4-dihydropyridine-3-carbothioic S-acid, 1,2-ETHANEDIOL, CALCIUM ION, ...
著者Gatreddi, S, Hausinger, R.P, Hu, J.
登録日2022-10-31
公開日2023-01-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Irreversible inactivation of lactate racemase by sodium borohydride reveals reactivity of the nickel-pincer nucleotide cofactor.
Acs Catalysis, 13, 2023
8EZI
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A tethered niacin-derived pincer complex with a nickel-carbon bond in lactate racemase R98A/R100A variant modeled with separated sulfite and NPN
分子名称: 1,2-ETHANEDIOL, 3-methanethioyl-1-(5-O-phosphono-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridin-1-ium, CALCIUM ION, ...
著者Gatreddi, S, Hausinger, R.P, Hu, J.
登録日2022-10-31
公開日2023-01-25
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Irreversible inactivation of lactate racemase by sodium borohydride reveals reactivity of the nickel-pincer nucleotide cofactor.
Acs Catalysis, 13, 2023
8EZH
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BU of 8ezh by Molmil
A tethered niacin-derived pincer complex with a nickel-carbon bond in lactate racemase R98A/R100A variant modeled with sulfite-NPN adduct
分子名称: (4S)-5-methanethioyl-1-(5-O-phosphono-beta-D-ribofuranosyl)-4-sulfo-1,4-dihydropyridine-3-carbothioic S-acid, 1,2-ETHANEDIOL, CALCIUM ION, ...
著者Gatreddi, S, Hausinger, R.P, Hu, J.
登録日2022-10-31
公開日2023-01-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Irreversible inactivation of lactate racemase by sodium borohydride reveals reactivity of the nickel-pincer nucleotide cofactor.
Acs Catalysis, 13, 2023
6UTR
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BU of 6utr by Molmil
LarE, a sulfur transferase involved in synthesis of the cofactor for lactate racemase in complex with copper
分子名称: ATP-dependent sacrificial sulfur transferase LarE, COPPER (II) ION, PHOSPHATE ION, ...
著者Fellner, M, Huizenga, K, Hausinger, R.P, Hu, J.
登録日2019-10-29
公開日2019-11-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Crystallographic characterization of a tri-Asp metal-binding site at the three-fold symmetry axis of LarE.
Sci Rep, 10, 2020
6UTQ
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LarE, a sulfur transferase involved in synthesis of the cofactor for lactate racemase in complex with cadmium
分子名称: ATP-dependent sacrificial sulfur transferase LarE, CADMIUM ION, PHOSPHATE ION, ...
著者Fellner, M, Huizenga, K, Hausinger, R.P, Hu, J.
登録日2019-10-29
公開日2019-11-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Crystallographic characterization of a tri-Asp metal-binding site at the three-fold symmetry axis of LarE.
Sci Rep, 10, 2020
6UTT
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BU of 6utt by Molmil
LarE, a sulfur transferase involved in synthesis of the cofactor for lactate racemase in complex with calcium
分子名称: ATP-dependent sacrificial sulfur transferase LarE, CALCIUM ION, PHOSPHATE ION, ...
著者Fellner, M, Huizenga, K, Hausinger, R.P, Hu, J.
登録日2019-10-29
公開日2019-11-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Crystallographic characterization of a tri-Asp metal-binding site at the three-fold symmetry axis of LarE.
Sci Rep, 10, 2020
6UTP
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LarE, a sulfur transferase involved in synthesis of the cofactor for lactate racemase in complex with cobalt
分子名称: ATP-dependent sacrificial sulfur transferase LarE, COBALT (II) ION, PHOSPHATE ION, ...
著者Fellner, M, Huizenga, K, Hausinger, R.P, Hu, J.
登録日2019-10-29
公開日2019-11-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.55 Å)
主引用文献Crystallographic characterization of a tri-Asp metal-binding site at the three-fold symmetry axis of LarE.
Sci Rep, 10, 2020
6CBA
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BU of 6cba by Molmil
Ethylene forming enzyme in complex with manganese, 2-oxoglutarate and canavanine
分子名称: 2-OXOGLUTARIC ACID, 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, L-CANAVANINE, ...
著者Fellner, M, Martinez, S, Hu, J, Hausinger, R.P.
登録日2018-02-02
公開日2019-02-06
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (1.13 Å)
主引用文献Structural, Spectroscopic, and Computational Insights from Canavanine-Bound and Two Catalytically Compromised Variants of the Ethylene-Forming Enzyme.
Biochemistry, 2024
6CF3
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BU of 6cf3 by Molmil
Ethylene forming enzyme Y306A variant in complex with manganese and 2-oxoglutarate
分子名称: 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, ...
著者Fellner, M, Martinez, S, Hu, J, Hausinger, R.P.
登録日2018-02-13
公開日2019-02-13
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献Structural, Spectroscopic, and Computational Insights from Canavanine-Bound and Two Catalytically Compromised Variants of the Ethylene-Forming Enzyme.
Biochemistry, 2024
7S91
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BU of 7s91 by Molmil
Structure of the malate racemase mar2 apoprotein from Thermoanaerobacterium thermosaccharolyticum at 2.25 angstroms resolution
分子名称: CHLORIDE ION, Malate racemase Mar2
著者Gatreddi, S, Hausinger, R.P, Hu, J.
登録日2021-09-20
公開日2021-10-13
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural and mutational characterization of a malate racemase from the LarA superfamily.
Biometals, 36, 2023
7CTE
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BU of 7cte by Molmil
Human Origin Recognition Complex, ORC2-5
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Origin recognition complex subunit 2, Origin recognition complex subunit 3, ...
著者Cheng, J, Li, N, Wang, X, Hu, J, Zhai, Y, Gao, N.
登録日2020-08-18
公開日2021-01-06
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural insight into the assembly and conformational activation of human origin recognition complex.
Cell Discov, 6, 2020
7CTF
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Human origin recognition complex 1-5 State II
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Origin recognition complex subunit 1, Origin recognition complex subunit 2, ...
著者Cheng, J, Li, N, Wang, X, Hu, J, Zhai, Y, Gao, N.
登録日2020-08-18
公開日2021-01-06
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Structural insight into the assembly and conformational activation of human origin recognition complex.
Cell Discov, 6, 2020
7CTG
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BU of 7ctg by Molmil
Human Origin Recognition Complex, ORC1-5 State I
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Origin recognition complex subunit 1, Origin recognition complex subunit 2, ...
著者Cheng, J, Li, N, Wang, X, Hu, J, Zhai, Y, Gao, N.
登録日2020-08-18
公開日2021-01-06
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Structural insight into the assembly and conformational activation of human origin recognition complex.
Cell Discov, 6, 2020
5GNS
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BU of 5gns by Molmil
Structures of human Mitofusin 1 provide insight into mitochondrial tethering
分子名称: GUANOSINE-5'-TRIPHOSPHATE, Mitofusin-1
著者Qi, Y, Yan, L, Yu, C, Guo, X, Zhou, X, Hu, X, Huang, X, Rao, Z, Lou, Z, Hu, J.
登録日2016-07-24
公開日2016-12-07
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.702 Å)
主引用文献Structures of human Mitofusin 1 provide insight into mitochondrial tethering
To Be Published
5C7M
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BU of 5c7m by Molmil
CRYSTAL STRUCTURE OF E3 LIGASE ITCH WITH A UB VARIANT
分子名称: E3 ubiquitin-protein ligase Itchy homolog, Polyubiquitin-C
著者Walker, J.R, Hu, J, Dong, A, Wernimont, A, Zhang, W, Sidhu, S, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC)
登録日2015-06-24
公開日2016-03-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.03 Å)
主引用文献System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Mol.Cell, 62, 2016
5C7J
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CRYSTAL STRUCTURE OF NEDD4 WITH A UB VARIANT
分子名称: E3 ubiquitin-protein ligase NEDD4, Polyubiquitin-C
著者Walker, J.R, Hu, J, Dong, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC)
登録日2015-06-24
公開日2016-03-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Mol.Cell, 62, 2016
2NEF
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HIV-1 NEF (REGULATORY FACTOR), NMR, 40 STRUCTURES
分子名称: NEGATIVE FACTOR (F-PROTEIN)
著者Grzesiek, S, Bax, A, Clore, G.M, Gronenborn, A.M, Hu, J.S, Kaufman, J, Palmer, I, Stahl, S.J, Tjandra, N, Wingfield, P.T.
登録日1997-02-12
公開日1997-07-07
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Refined solution structure and backbone dynamics of HIV-1 Nef.
Protein Sci., 6, 1997

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