8EZF

A tethered niacin-derived pincer complex with a nickel-carbon or sulfite-carbon bond in lactate racemase R98A/R100A variant

Summary for 8EZF

• Entry DOI: 10.2210/pdb8ezf/pdb
• Descriptor: Lactate racemase, CALCIUM ION, MAGNESIUM ION, ... (8 entities in total)
• Functional Keywords: catalytic activity, isomerase activity, racemase and epimerase activity racemase acting on hydroxy acids and derivatives, isomerase, metal ion binding
• Biological source: Lactiplantibacillus plantarum WCFS1
• Total number of polymer chains: 1
• Total formula weight: 48598.44

Authors

Gatreddi, S.,Hausinger, R.P.,Hu, J. (deposition date: 2022-10-31, release date: 2023-01-25, Last modification date: 2023-11-08)

• Primary citation: Gatreddi, S.,Sui, D.,Hausinger, R.P.,Hu, J.; Irreversible inactivation of lactate racemase by sodium borohydride reveals reactivity of the nickel-pincer nucleotide cofactor.; Acs Catalysis, 13:1441-1448, 2023; PubMed: 37886035; DOI: 10.1021/acscatal.2c05461

Experimental method

X-RAY DIFFRACTION (2.15 Å)