Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 414 results

8VZP
DownloadVisualize
BU of 8vzp by Molmil
Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-403
Descriptor: (1S,2R,4S)-N-(2-hydroxyethyl)-5,6-bis(4-hydroxyphenyl)-N-(4-methoxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide, Estrogen receptor
Authors:Min, C.K, Nwachukwu, J.C, Hou, Y, Russo, R.J, Papa, A, Min, J, Peng, R, Kim, S.H, Ziegler, Y, Rangarajan, E.S, Izard, T, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Nettles, K.W.
Deposit date:2024-02-12
Release date:2024-06-12
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Asymmetric allostery in estrogen receptor-alpha homodimers drives responses to the ensemble of estrogens in the hormonal milieu.
Proc.Natl.Acad.Sci.USA, 121, 2024
6LLB
DownloadVisualize
BU of 6llb by Molmil
Crystal structure of mpy-RNase J (mutant S247A), an archaeal RNase J from Methanolobus psychrophilus R15, in complex with 6 nt RNA
Descriptor: MPY-RNase J, RNA (5'-R(P*AP*AP*AP*AP*AP*A)-3'), SULFATE ION, ...
Authors:Li, D.F, Hou, Y.J, Guo, L.
Deposit date:2019-12-22
Release date:2020-01-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A newly identified duplex RNA unwinding activity of archaeal RNase J depends on processive exoribonucleolysis coupled steric occlusion by its structural archaeal loops.
Rna Biol., 17, 2020
7CAM
DownloadVisualize
BU of 7cam by Molmil
SARS-CoV-2 main protease (Mpro) apo structure (space group P212121)
Descriptor: 3C-like proteinase
Authors:Wang, Y.C, Yang, C.S, Hou, M.H, Tsai, C.L, Chou, Y.Z, Chen, Y.
Deposit date:2020-06-09
Release date:2021-05-05
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural basis of SARS-CoV-2 main protease inhibition by a broad-spectrum anti-coronaviral drug.
Am J Cancer Res, 10, 2020
7CB7
DownloadVisualize
BU of 7cb7 by Molmil
1.7A resolution structure of SARS-CoV-2 main protease (Mpro) in complex with broad-spectrum coronavirus protease inhibitor GC376
Descriptor: (1R,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase, ...
Authors:Wang, Y.C, Yang, C.S, Hou, M.H, Tsai, C.L, Chou, Y.Z, Chen, Y, Hung, M.C.
Deposit date:2020-06-10
Release date:2021-05-05
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Structural basis of SARS-CoV-2 main protease inhibition by a broad-spectrum anti-coronaviral drug.
Am J Cancer Res, 10, 2020
7SS9
DownloadVisualize
BU of 7ss9 by Molmil
Late translocation intermediate with EF-G partially dissociated (Structure V)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Carbone, C.E, Loveland, A.B, Gamper, H.B, Hou, Y, Korostelev, A.A.
Deposit date:2021-11-10
Release date:2022-02-23
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP.
Nat Commun, 12, 2021
7C8Z
DownloadVisualize
BU of 7c8z by Molmil
Crystal structure of salicylate 5-hydroxylase NagGH (a Rieske non-heme iron-dependent monooxgenase)
Descriptor: FE (III) ION, FE2/S2 (INORGANIC) CLUSTER, Salicylate 5-hydroxylase, ...
Authors:Li, D.F, Hou, Y.J.
Deposit date:2020-06-04
Release date:2021-01-06
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and Biochemical Analysis Reveals a Distinct Catalytic Site of Salicylate 5-Monooxygenase NagGH from Rieske Dioxygenases.
Appl.Environ.Microbiol., 87, 2021
8J6K
DownloadVisualize
BU of 8j6k by Molmil
Crystal structure of pro-interleukin-18 and caspase-4 complex
Descriptor: Arginine ADP-riboxanase OspC3, Caspase-4 subunit p10, Caspase-4 subunit p20, ...
Authors:Sun, Q, Hou, Y.J, Ding, J.
Deposit date:2023-04-26
Release date:2023-11-29
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:Recognition and maturation of IL-18 by caspase-4 noncanonical inflammasome.
Nature, 624, 2023
8IVB
DownloadVisualize
BU of 8ivb by Molmil
K113-Ubiquitinated BAK
Descriptor: Bcl-2 homologous antagonist/killer, Ubiquitin
Authors:Dong, X, Cheng, P, Hou, Y.Z, Chen, Y.K, Liu, Z.
Deposit date:2023-03-26
Release date:2024-01-31
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Parkin-mediated ubiquitination inhibits BAK apoptotic activity by blocking its canonical hydrophobic groove.
Commun Biol, 6, 2023
8JYV
DownloadVisualize
BU of 8jyv by Molmil
Crystal structure of the gasdermin from Trichoplax adhaerens
Descriptor: Gasdermin pore forming domain-containing protein
Authors:Zeng, H, Hou, Y.J, Ding, J.
Deposit date:2023-07-04
Release date:2024-05-01
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Cleavage-independent activation of ancient eukaryotic gasdermins and structural mechanisms.
Science, 384, 2024
8JYY
DownloadVisualize
BU of 8jyy by Molmil
Crystal structure of the gasdermin-like protein RCD-1-2 from Neurospora crassa
Descriptor: RCD-1-2
Authors:Li, Y, Hou, Y.J, Ding, J.
Deposit date:2023-07-04
Release date:2024-05-01
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Cleavage-independent activation of ancient eukaryotic gasdermins and structural mechanisms.
Science, 384, 2024
8JYX
DownloadVisualize
BU of 8jyx by Molmil
Crystal structure of the gasdermin-like protein RCD-1-1 from Neurospora crassa
Descriptor: Maltodextrin-binding protein,Gasdermin-like protein rcd-1-1, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Li, Y, Hou, Y.J, Ding, J.
Deposit date:2023-07-04
Release date:2024-05-08
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Cleavage-independent activation of ancient eukaryotic gasdermins and structural mechanisms.
Science, 384, 2024
8GTK
DownloadVisualize
BU of 8gtk by Molmil
Crystal structure of IpaH7.8-LRR and GSDMB isoform-1 complex
Descriptor: GSDMB isoform-1, Probable E3 ubiquitin-protein ligase ipaH7.8
Authors:Zhong, X, Hou, Y.J, Ding, J.
Deposit date:2022-09-08
Release date:2023-04-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural mechanisms for regulation of GSDMB pore-forming activity.
Nature, 616, 2023
8GTJ
DownloadVisualize
BU of 8gtj by Molmil
Crystal structure of IpaH7.8-LRR and GSDMB isoform-4 complex
Descriptor: Isoform 4 of Gasdermin-B, Probable E3 ubiquitin-protein ligase ipaH7.8
Authors:Zhong, X, Hou, Y.J, Ding, J.
Deposit date:2022-09-08
Release date:2023-04-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural mechanisms for regulation of GSDMB pore-forming activity.
Nature, 616, 2023
7LV0
DownloadVisualize
BU of 7lv0 by Molmil
Pre-translocation rotated ribosome +1-frameshifting(CCC-A) complex (Structure Irot-FS)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Demo, G, Loveland, A.B, Svidritskiy, E, Gamper, H.B, Hou, Y.M, Korostelev, A.A.
Deposit date:2021-02-23
Release date:2021-07-28
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation.
Nat Commun, 12, 2021
7K52
DownloadVisualize
BU of 7k52 by Molmil
Near post-translocated non-frameshifting(CCA-A) complex with EF-G and GDPCP (Structure III)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Demo, G, Loveland, A.B, Svidritskiy, E, Gamper, H.B, Hou, Y.M, Korostelev, A.A.
Deposit date:2020-09-16
Release date:2021-07-28
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation.
Nat Commun, 12, 2021
7K53
DownloadVisualize
BU of 7k53 by Molmil
Pre-translocation +1-frameshifting(CCC-A) complex (Structure I-FS)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Demo, G, Loveland, A.B, Svidritskiy, E, Gamper, H.B, Hou, Y.M, Korostelev, A.A.
Deposit date:2020-09-16
Release date:2021-07-28
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation.
Nat Commun, 12, 2021
7K55
DownloadVisualize
BU of 7k55 by Molmil
Near post-translocated +1-frameshifting(CCC-A) complex with EF-G and GDPCP (Structure III-FS)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Demo, G, Loveland, A.B, Svidritskiy, E, Gamper, H.B, Hou, Y.M, Korostelev, A.A.
Deposit date:2020-09-16
Release date:2021-07-28
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation.
Nat Commun, 12, 2021
7K51
DownloadVisualize
BU of 7k51 by Molmil
Mid-translocated non-frameshifting(CCA-A) complex with EF-G and GDPCP (Structure II)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Demo, G, Loveland, A.B, Svidritskiy, E, Gamper, H.B, Hou, Y.M, Korostelev, A.A.
Deposit date:2020-09-16
Release date:2021-07-28
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation.
Nat Commun, 12, 2021
7K50
DownloadVisualize
BU of 7k50 by Molmil
Pre-translocation non-frameshifting(CCA-A) complex (Structure I)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Demo, G, Loveland, A.B, Svidritskiy, E, Gamper, H.B, Hou, Y.M, Korostelev, A.A.
Deposit date:2020-09-16
Release date:2021-07-28
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation.
Nat Commun, 12, 2021
1LI5
DownloadVisualize
BU of 1li5 by Molmil
Crystal Structure of Cysteinyl-tRNA Synthetase
Descriptor: CYSTEINYL-TRNA SYNTHETASE, ZINC ION
Authors:Newberry, K.J, Hou, Y.-M, Perona, J.J.
Deposit date:2002-04-17
Release date:2002-04-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural origins of amino acid selection without editing by cysteinyl-tRNA synthetase
EMBO J., 21, 2002
1LI7
DownloadVisualize
BU of 1li7 by Molmil
Crystal Structure of Cysteinyl-tRNA Synthetase with Cysteine Substrate Bound
Descriptor: CYSTEINE, CYSTEINYL-TRNA SYNTHETASE, ZINC ION
Authors:Newberry, K.J, Hou, Y.-M, Perona, J.J.
Deposit date:2002-04-17
Release date:2002-04-26
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural origins of amino acid selection without editing by cysteinyl-tRNA synthetase
EMBO J., 21, 2002
7K54
DownloadVisualize
BU of 7k54 by Molmil
Mid-translocated +1-frameshifting(CCC-A) complex with EF-G and GDPCP (Structure II-FS)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Demo, G, Loveland, A.B, Svidritskiy, E, Gamper, H.B, Hou, Y.M, Korostelev, A.A.
Deposit date:2020-09-16
Release date:2021-07-28
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation.
Nat Commun, 12, 2021
1EUY
DownloadVisualize
BU of 1euy by Molmil
GLUTAMINYL-TRNA SYNTHETASE COMPLEXED WITH A TRNA MUTANT AND AN ACTIVE SITE INHIBITOR
Descriptor: 5'-O-[N-(L-GLUTAMINYL)-SULFAMOYL]ADENOSINE, GLUTAMINYL TRNA, GLUTAMINYL-TRNA SYNTHETASE
Authors:Sherlin, L.D, Bullock, T.L, Newberry, K.J, Lipman, R.S.A, Hou, Y.-M, Beijer, B, Sproat, B.S, Perona, J.J.
Deposit date:2000-04-19
Release date:2000-06-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Influence of transfer RNA tertiary structure on aminoacylation efficiency by glutaminyl and cysteinyl-tRNA synthetases.
J.Mol.Biol., 299, 2000
1EUQ
DownloadVisualize
BU of 1euq by Molmil
CRYSTAL STRUCTURE OF GLUTAMINYL-TRNA SYNTHETASE COMPLEXED WITH A TRNA-GLN MUTANT AND AN ACTIVE-SITE INHIBITOR
Descriptor: 5'-O-[N-(L-GLUTAMINYL)-SULFAMOYL]ADENOSINE, GLUTAMINYL TRNA, GLUTAMINYL-TRNA SYNTHETASE
Authors:Sherlin, L.D, Bullock, T.L, Newberry, K.J, Lipman, R.S.A, Hou, Y.-M, Beijer, B, Sproat, B.S, Perona, J.J.
Deposit date:2000-04-17
Release date:2000-06-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Influence of transfer RNA tertiary structure on aminoacylation efficiency by glutaminyl and cysteinyl-tRNA synthetases.
J.Mol.Biol., 299, 2000
5Z2L
DownloadVisualize
BU of 5z2l by Molmil
Crystal structure of BdcA in complex with NADPH
Descriptor: 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, Cyclic-di-GMP-binding biofilm dispersal mediator protein, ...
Authors:Yang, W.S, Hou, Y.J, Li, D.F, Wang, D.C.
Deposit date:2018-01-03
Release date:2018-03-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A potential substrate binding pocket of BdcA plays a critical role in NADPH recognition and biofilm dispersal
Biochem. Biophys. Res. Commun., 497, 2018

222624

數據於2024-07-17公開中

PDB statisticsPDBj update infoContact PDBjnumon