3AQS
 
 | | Crystal structure of RolR (NCGL1110) without ligand | | 分子名称: | Bacterial regulatory proteins, tetR family | | 著者 | Li, D.F, Zhang, N, Hou, Y.J, Liu, S.J, Wang, D.C. | | 登録日 | 2010-11-18 | | 公開日 | 2011-07-06 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Crystal structures of the transcriptional repressor RolR reveals a novel recognition mechanism between inducer and regulator.
Plos One, 6, 2011
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3AQT
 | | CRYSTAL STRUCTURE OF RolR (NCGL1110) complex WITH ligand RESORCINOL | | 分子名称: | Bacterial regulatory proteins, tetR family, RESORCINOL | | 著者 | Li, D.F, Zhang, N, Hou, Y.J, Liu, S.J, Wang, D.C. | | 登録日 | 2010-11-18 | | 公開日 | 2011-07-06 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structures of the transcriptional repressor RolR reveals a novel recognition mechanism between inducer and regulator.
Plos One, 6, 2011
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6XVD
 | | Crystal structure of complex of urokinase and a upain-1 variant(W3F) in pH7.4 condition | | 分子名称: | Urokinase-type plasminogen activator, upain-1-W3F | | 著者 | Xue, G.P, Xie, X, Zhou, Y, Yuan, C, Huang, M.D, Jiang, L.G. | | 登録日 | 2020-01-21 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Insight to the residue in P2 position prevents the peptide inhibitor from being hydrolyzed by serine proteases.
Biosci.Biotechnol.Biochem., 84, 2020
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3AXZ
 | | Crystal structure of Haemophilus influenzae TrmD in complex with adenosine | | 分子名称: | ADENOSINE, tRNA (guanine-N(1)-)-methyltransferase | | 著者 | Yoshida, K, Goto-Ito, S, Ito, T, Hou, Y.M, Yokoyama, S. | | 登録日 | 2011-04-21 | | 公開日 | 2011-08-17 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Differentiating analogous tRNA methyltransferases by fragments of the methyl donor.
Rna, 17, 2011
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3VSJ
 | | Crystal structure of 1,6-APD (2-ANIMOPHENOL-1,6-DIOXYGENASE) complexed with intermediate products | | 分子名称: | (2Z,4Z)-2-imino-6-oxohex-4-enoic acid, (3E)-3-iminooxepin-2(3H)-one, 2-amino-5-chlorophenol 1,6-dioxygenase alpha subunit, ... | | 著者 | Li, D.F, Hou, Y.J, Hu, Y, Wang, D.C, Liu, W. | | 登録日 | 2012-04-25 | | 公開日 | 2013-01-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structures of aminophenol dioxygenase in complex with intermediate, product and inhibitor
Acta Crystallogr.,Sect.D, 69, 2013
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3VSH
 | | Crystal structure of native 1,6-APD (with Iron), 2-Animophenol-1,6-Dioxygenase | | 分子名称: | 2-amino-5-chlorophenol 1,6-dioxygenase alpha subunit, 2-amino-5-chlorophenol 1,6-dioxygenase beta subunit, FE (II) ION | | 著者 | Li, D.F, Hou, Y.J, Hu, Y, Wang, D.C, Liu, W. | | 登録日 | 2012-04-25 | | 公開日 | 2013-01-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structures of aminophenol dioxygenase in complex with intermediate, product and inhibitor
Acta Crystallogr.,Sect.D, 69, 2013
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3WJM
 | | Crystal structure of Bombyx mori Sp2/Sp3 heterohexamer | | 分子名称: | Arylphorin, Silkworm storage protein, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Yuan, Y.A, Hou, Y. | | 登録日 | 2013-10-11 | | 公開日 | 2014-09-24 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of Bombyx mori arylphorins reveals a 3:3 heterohexamer with multiple papain cleavage sites
Protein Sci., 23, 2014
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3WMS
 | | The crystal structure of Y195I mutant alpha-cyclodextrin glycosyltransferase from Paenibacillus macerans | | 分子名称: | Alpha-cyclodextrin glucanotransferase, CALCIUM ION | | 著者 | Xie, T, Hou, Y.J, Li, D.F, Yue, Y, Qian, S.J, Chao, Y.P. | | 登録日 | 2013-11-24 | | 公開日 | 2014-11-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis of a mutant Y195I alpha-cyclodextrin glycosyltransferase with switched product specificity from alpha-cyclodextrin to beta-/ gamma-cyclodextrin
J.Biotechnol., 182-183, 2014
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3AY0
 | | Crystal structure of Methanocaldococcus jannaschii Trm5 in complex with adenosine | | 分子名称: | ADENOSINE, Uncharacterized protein MJ0883, ZINC ION | | 著者 | Goto-Ito, S, Ito, T, Hou, Y.M, Yokoyama, S. | | 登録日 | 2011-04-21 | | 公開日 | 2011-08-17 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Differentiating analogous tRNA methyltransferases by fragments of the methyl donor.
Rna, 17, 2011
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3UST
 | | Structure of BmNPV ORF075 (p33) | | 分子名称: | AcMNPV orf92, FLAVIN-ADENINE DINUCLEOTIDE | | 著者 | Yuan, Y.A, Hou, Y, Xia, Q. | | 登録日 | 2011-11-23 | | 公開日 | 2012-10-10 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of Bombyx mori nucleopolyhedrovirus ORF75 reveals a pseudo-dimer of thiol oxidase domains with a putative substrate-binding pocket
J.Gen.Virol., 93, 2012
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1U0B
 | | Crystal structure of cysteinyl-tRNA synthetase binary complex with tRNACys | | 分子名称: | Cysteine--tRNA ligase, ZINC ION, cysteinyl tRNA | | 著者 | Hauenstein, S, Zhang, C.M, Hou, Y.M, Perona, J.J. | | 登録日 | 2004-07-13 | | 公開日 | 2004-11-23 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Shape-selective RNA recognition by cysteinyl-tRNA synthetase
Nat.Struct.Mol.Biol., 11, 2004
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5YL4
 | | CRYSTAL STRUCTURE OF T2R-TTL-8WR COMPLEX | | 分子名称: | (3Z,6Z)-3-[(4-tert-butyl-1H-imidazol-5-yl)methylidene]-6-[[3-(phenylcarbonyl)phenyl]methylidene]piperazine-2,5-dione, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Fu, Z.Y, Li, W.B, Chu, Y.Y, Hou, Y.W, Ji, C.P. | | 登録日 | 2017-10-17 | | 公開日 | 2017-11-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | | 主引用文献 | Design, synthesis and biological activity evaluation of plinabulin derivatives based on co-crystal structure
To Be Published
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1YM4
 | | Crystal structure of human beta secretase complexed with NVP-AMK640 | | 分子名称: | Beta-secretase 1, NVP-AMK640 INHIBITOR | | 著者 | Hanessian, S, Yun, H, Hou, Y, Yang, G, Bayrakdarian, M, Therrien, E, Moitessier, N, Roggo, S, Veenstra, S. | | 登録日 | 2005-01-20 | | 公開日 | 2006-01-17 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structure-based design, synthesis, and memapsin 2 (BACE) inhibitory activity of carbocyclic and heterocyclic peptidomimetics
J.Med.Chem., 48, 2005
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1YM2
 | | Crystal structure of human beta secretase complexed with NVP-AUR200 | | 分子名称: | Beta-secretase 1, NVP-AUR200 INHIBITOR | | 著者 | Hanessian, S, Yun, H, Hou, Y, Yang, G, Bayrakdarian, M, Therrien, E, Moitessier, N, Roggo, S, Veenstra, S. | | 登録日 | 2005-01-20 | | 公開日 | 2006-01-17 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structure-based design, synthesis, and memapsin 2 (BACE) inhibitory activity of carbocyclic and heterocyclic peptidomimetics
J.Med.Chem., 48, 2005
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4V60
 | | The structure of rat liver vault at 3.5 angstrom resolution | | 分子名称: | Major vault protein | | 著者 | Kato, K, Zhou, Y, Tanaka, H, Yao, M, Yamashita, E, Yoshimura, M, Tsukihara, T. | | 登録日 | 2008-10-24 | | 公開日 | 2014-07-09 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | The structure of rat liver vault at 3.5 angstrom resolution
Science, 323, 2009
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7CZ5
 | | Cryo-EM structure of the human growth hormone-releasing hormone receptor-Gs protein complex | | 分子名称: | CHOLESTEROL, Growth hormone-releasing hormone receptor,growth hormone-releasing hormone receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Zhou, F, Zhang, H, Cong, Z, Zhao, L, Zhou, Q, Mao, C, Cheng, X, Shen, D, Cai, X, Ma, C, Wang, Y, Dai, A, Zhou, Y, Sun, W, Zhao, F, Zhao, S, Jiang, H, Jiang, Y, Yang, D, Xu, H.E, Zhang, Y, Wang, M. | | 登録日 | 2020-09-07 | | 公開日 | 2020-11-18 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Structural basis for activation of the growth hormone-releasing hormone receptor.
Nat Commun, 11, 2020
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7D68
 | | Cryo-EM structure of the human glucagon-like peptide-2 receptor-Gs protein complex | | 分子名称: | Glucagon-like peptide 2 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Sun, W, Chen, L, Zhou, Q, Zhao, L, Zhang, H, Cong, Z, Shen, D, Zhao, F, Zhou, F, Cai, X, Chen, Y, Zhou, Y, Gadgaard, S, van der Velden, W.J, Zhao, S, Jiang, Y, Rosenkilde, M.M, Yang, D, Xu, H.E, Zhang, Y, Wang, M. | | 登録日 | 2020-09-29 | | 公開日 | 2020-12-16 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor.
Cell Res., 30, 2020
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6L14
 | | Crystal structure of Ser/Thr kinase Pim1 in complex with 10-DEBC derivatives | | 分子名称: | 2-chloranyl-10-[3-[(3~{S})-piperidin-3-yl]propyl]phenoxazine, Serine/threonine-protein kinase pim-1 | | 著者 | Zhang, W, Xie, Y, Cao, R, Huang, N, Zhou, Y. | | 登録日 | 2019-09-27 | | 公開日 | 2020-05-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structure-Based Optimization of 10-DEBC Derivatives as Potent and Selective Pim-1 Kinase Inhibitors.
J.Chem.Inf.Model., 60, 2020
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6L13
 | | Crystal structure of Ser/Thr kinase Pim1 in complex with 10-DEBC derivatives | | 分子名称: | 2-chloranyl-10-(2-piperidin-4-ylethyl)phenoxazine, Serine/threonine-protein kinase pim-1 | | 著者 | Zhang, W, Xie, Y, Cao, R, Huang, N, Zhou, Y. | | 登録日 | 2019-09-27 | | 公開日 | 2020-05-27 | | 最終更新日 | 2020-07-08 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | Structure-Based Optimization of 10-DEBC Derivatives as Potent and Selective Pim-1 Kinase Inhibitors.
J.Chem.Inf.Model., 60, 2020
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2GCQ
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6LE8
 | | Crystal structure of nematode family I chitinase,CeCht1, in complex with dihydropyrrolopyrazol-6-one derivate 1 | | 分子名称: | (4R)-4-(4-ethoxyphenyl)-3-(2-hydroxyphenyl)-5-(pyridin-3-ylmethyl)-1,4-dihydropyrrolo[3,4-c]pyrazol-6-one, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, ... | | 著者 | Chen, Q, Yang, Q, Zhou, Y. | | 登録日 | 2019-11-24 | | 公開日 | 2021-05-26 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.39909327 Å) | | 主引用文献 | Crystal structure of nematode family I chitinase,CeCht1, in complex with dihydropyrrolopyrazol-6-one derivate 1
To Be Published
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7DHR
 | | Cryo-EM structure of the full agonist isoprenaline-bound beta2 adrenergic receptor-Gs protein complex. | | 分子名称: | Beta-2 adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Yang, F, Ling, S.L, Zhou, Y.X, Zhang, Y.N, Lv, P, Liu, S.L, Fang, W, Sun, W.J, Hu, L.Y.A. | | 登録日 | 2020-11-17 | | 公開日 | 2020-12-16 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Different Conformational Responses of the beta2-Adrenergic Receptor-Gs Complex upon Binding of the Partial Agonist Salbutamol or the Full Agonist Isoprenaline
Natl Sci Rev, 2020
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6LDU
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6LE7
 | | Crystal structure of nematode family I chitinase,CeCht1, in complex with dihydropyrrolopyrazol-6-one derivate 2 | | 分子名称: | (4R)-3-(2-hydroxyphenyl)-4-(3-methoxy-4-propoxy-phenyl)-5-(pyridin-3-ylmethyl)-1,4-dihydropyrrolo[3,4-c]pyrazol-6-one, Probable endochitinase | | 著者 | Chen, Q, Yang, Q, Zhou, Y. | | 登録日 | 2019-11-24 | | 公開日 | 2021-05-26 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.85753441 Å) | | 主引用文献 | Crystal structure of nematode family I chitinase,CeCht1, in complex with dihydropyrrolopyrazol-6-one derivate 2
To Be Published
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8T2I
 | | Negative stain EM assembly of MYC, JAZ, and NINJA complex | | 分子名称: | AFP homolog 2, Maltose/maltodextrin-binding periplasmic protein, Protein TIFY 10A, ... | | 著者 | Zhou, X.E, Zhang, Y, Zhou, Y, He, Q, Cao, X, Kariapper, L, Suino-Powell, K, Zhu, Y, Zhang, F, Karsten, M. | | 登録日 | 2023-06-06 | | 公開日 | 2023-06-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (10.4 Å) | | 主引用文献 | Assembly of JAZ-JAZ and JAZ-NINJA complexes in jasmonate signaling.
Plant Commun., 4, 2023
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