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PDB: 177 件
4XNY
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BU of 4xny by Molmil
Crystal structure of broadly and potently neutralizing antibody VRC08C in complex with HIV-1 clade A strain Q842.d12 gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160,Envelope glycoprotein gp160,Envelope glycoprotein gp160, HEAVY CHAIN OF ANTIBODY VRC08C, ...
著者Zhou, T, Srivatsan, S, Kwong, P.D.
登録日2015-01-16
公開日2015-04-29
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection.
Cell, 161, 2015
4XNZ
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BU of 4xnz by Molmil
Crystal structure of broadly and potently neutralizing antibody VRC06B in complex with HIV-1 clade A/E strain 93TH057 gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160,Envelope glycoprotein gp160, ...
著者Zhou, T, Srivatsan, S, Kwong, P.D.
登録日2015-01-16
公開日2015-04-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.389 Å)
主引用文献Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection.
Cell, 161, 2015
7JKS
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BU of 7jks by Molmil
Crystal structure of vaccine-elicited broadly neutralizing VRC01-class antibody 2411a in complex with HIV-1 gp120 core
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 gp120 core, The heavy chain of antibody 2411a, ...
著者Zhou, T, Chen, X, Kwong, P.D, Mascola, J.R.
登録日2020-07-28
公開日2021-06-09
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Vaccination induces maturation in a mouse model of diverse unmutated VRC01-class precursors to HIV-neutralizing antibodies with >50% breadth.
Immunity, 54, 2021
7JKT
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BU of 7jkt by Molmil
Crystal structure of vaccine-elicited broadly neutralizing VRC01-class antibody 2413a in complex with HIV-1 gp120 core
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HIV-1 gp120 core from strain d45-01dG5, ...
著者Zhou, T, Chen, X, Kwong, P.D, Mascola, J.R.
登録日2020-07-28
公開日2021-06-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Vaccination induces maturation in a mouse model of diverse unmutated VRC01-class precursors to HIV-neutralizing antibodies with >50% breadth.
Immunity, 54, 2021
7TB4
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BU of 7tb4 by Molmil
Cryo-EM structure of the spike of SARS-CoV-2 Omicron variant of concern
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Surface glycoprotein
著者Zhou, T, Tsybovsky, T, Kwong, P.D.
登録日2021-12-21
公開日2022-01-12
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Antibodies with potent and broad neutralizing activity against antigenically diverse and highly transmissible SARS-CoV-2 variants.
Biorxiv, 2021
7TBF
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BU of 7tbf by Molmil
Locally refined region of SARS-CoV-2 spike in complex with antibodies B1-182.1 and A19-61.1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of SARS-CoV-2 antibody A19-61.1, Heavy chain of SARS-CoV-2 antibody B1-182.1, ...
著者Zhou, T, Tsybovsky, T, Kwong, P.D.
登録日2021-12-21
公開日2022-03-30
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529.
Science, 376, 2022
7TB8
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BU of 7tb8 by Molmil
Cryo-EM structure of SARS-CoV-2 spike in complex with antibodies B1-182.1 and A19-61.1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhou, T, Tsybovsky, T, Kwong, P.D.
登録日2021-12-21
公開日2022-03-30
最終更新日2022-10-19
実験手法ELECTRON MICROSCOPY (2.83 Å)
主引用文献Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529.
Science, 376, 2022
7L77
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BU of 7l77 by Molmil
Crystal structure of broadly HIV-1-neutralizing antibody VRC33.01
分子名称: Heavy chain of VRC 33.01, Light chain of VRC33.01
著者Zhou, T, Kwong, P.D.
登録日2020-12-27
公開日2021-10-27
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.543 Å)
主引用文献Crystal structure of broadly HIV-1-neutralizing antibody
Cell Rep, 2021
7L79
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BU of 7l79 by Molmil
Crystal structure of broadly HIV-1-neutralizing antibody VRC40.01
分子名称: Heavy chain of VRC40.01, Light chain of VRC40.01, ZINC ION
著者Zhou, T, Kwong, P.D.
登録日2020-12-27
公開日2021-10-27
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.826 Å)
主引用文献Crystal structure of broadly HIV-1-neutralizing antibody
Cell Rep, 2021
8TNH
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BU of 8tnh by Molmil
Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with broadly neutralizing llama nanobody G36 targeting the CD4-binding site
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD4-binding site nanobody G36, ...
著者Zhou, T, Kwong, P.D, Xu, J.
登録日2023-08-01
公開日2024-05-08
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.32 Å)
主引用文献Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with broadly neutralizing llama nanobody G36 targeting the CD4-binding site
To Be Published
8TNI
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BU of 8tni by Molmil
Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with broadly neutralizing bi-specific antibody CAP256L-R27 targeting the CD4-binding site and the V2-apex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 BG505 DS-SOSIP gp120, ...
著者Zhou, T, Morano, N.C, Roark, R.S, Kwong, P.D, Xu, J.
登録日2023-08-01
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (3.61 Å)
主引用文献Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with broadly neutralizing bi-specific antibody CAP256L-R27 targeting the CD4-binding site and the V2-apex
To Be Published
8TNG
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BU of 8tng by Molmil
Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with broadly neutralizing llama nanobody R27 targeting the CD4-binding site
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD4-binding site targeting nanobody R27, ...
著者Zhou, T, Kwong, P.D, Xu, J.
登録日2023-08-01
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (3.58 Å)
主引用文献Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with broadly neutralizing llama nanobody R27 targeting the CD4-binding site
To Be Published
7TCA
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BU of 7tca by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron spike in complex with antibody A19-46.1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of antibody A19-46.1, ...
著者Zhou, T, Kwong, P.D.
登録日2021-12-23
公開日2022-03-30
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.85 Å)
主引用文献Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529.
Science, 376, 2022
7TCC
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BU of 7tcc by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron spike in complex with antibodies A19-46.1 and B1-182.1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of antibody A19-46.1, ...
著者Zhou, T, Kwong, P.D.
登録日2021-12-23
公開日2022-03-30
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.86 Å)
主引用文献Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529.
Science, 376, 2022
7TC9
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BU of 7tc9 by Molmil
Locally refined region of SARS-CoV-2 spike in complex with antibody A19-46.1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of antibody A19-46.1, Light chain of antibody A19-46.1, ...
著者Zhou, T, Kwong, P.D.
登録日2021-12-23
公開日2022-03-30
最終更新日2022-10-19
実験手法ELECTRON MICROSCOPY (5.08 Å)
主引用文献Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529.
Science, 376, 2022
7U0D
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BU of 7u0d by Molmil
Local refinement of cryo-EM structure of the interface of the Omicron RBD in complex with antibodies B-182.1 and A19-46.1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of SARS-CoV-2 antibody A19-46.1, Heavy chain of SARS-CoV-2 antibody B1-182.1, ...
著者Zhou, T, kwong, P.D.
登録日2022-02-17
公開日2022-03-30
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529.
Science, 376, 2022
7R73
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BU of 7r73 by Molmil
Crystal structure of llama VHH antibody D7 in complex with HIV-1 gp120 core
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein 120, Llama antibody D7
著者Zhou, T, Kwong, P.D.
登録日2021-06-24
公開日2022-03-30
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site.
Structure, 30, 2022
7R74
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BU of 7r74 by Molmil
Crystal structure of llama VHH antibody in complex with HIV-1 HXBC2 gp120 core
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody C8 VHH domain, Glycoprotein 120
著者Zhou, T, Kwong, P.D.
登録日2021-06-24
公開日2022-03-30
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site.
Structure, 30, 2022
7RI2
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BU of 7ri2 by Molmil
Crystal structure of anti-HIV llama VHH antibody A12 in complex with HIV-1 C1086 gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein 120, anti-HIV llama VHH antibody A12
著者Zhou, T, Kwong, P.D.
登録日2021-07-19
公開日2022-03-30
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site.
Structure, 30, 2022
7RI1
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BU of 7ri1 by Molmil
Crystal structure of anti-HIV llama VHH antibody J3 in complex with HIV-1 C1086 gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein 120, Lamma VHH antibody J3, ...
著者Zhou, T, Kwong, P.D.
登録日2021-07-19
公開日2022-03-30
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site.
Structure, 30, 2022
5TE6
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BU of 5te6 by Molmil
Crystal Structure of Broadly Neutralizing VRC01-class Antibody N6 in Complex with HIV-1 Clade AE Strain 93TH057 gp120 Core
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Heavy chain of N6, ...
著者Zhou, T, Kwong, P.D.
登録日2016-09-20
公開日2016-11-16
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth.
Immunity, 45, 2016
5TE7
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BU of 5te7 by Molmil
Crystal Structure of Broadly Neutralizing VRC01-class Antibody N6 in Complex with HIV-1 Clade C Strain DU172.17 gp120 Core
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Zhou, T, Kwong, P.D.
登録日2016-09-20
公開日2016-11-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth.
Immunity, 45, 2016
8FBW
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BU of 8fbw by Molmil
Crystal structure of SIV-1 V2 antibody NCI05 in complex with a V2 peptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, DI(HYDROXYETHYL)ETHER, ...
著者Zhou, T, Kwong, P.D, Van Wazer, D.J.
登録日2022-11-30
公開日2023-01-18
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Effect of Passive Administration of Monoclonal Antibodies Recognizing Simian Immunodeficiency Virus (SIV) V2 in CH59-Like Coil/Helical or beta-Sheet Conformations on Time of SIV mac251 Acquisition.
J.Virol., 97, 2023
6T00
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BU of 6t00 by Molmil
Crystal structure of Cold Shock Protein B (CSP-B) containing 4-F-Phe modified residues
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Cold shock protein CspD, GLYCEROL
著者Zhou, T, Mayans, O.
登録日2019-10-02
公開日2020-02-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献What does fluorine do to a protein? Thermodynamic, and highly-resolved structural insights into fluorine-labelled variants of the cold shock protein.
Sci Rep, 10, 2020
6SZZ
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BU of 6szz by Molmil
Crystal structure of Cold Shock Protein B (CspB) containing the modified residue 4-F-Trp
分子名称: Cold shock protein CspD, GLYCEROL
著者Zhou, T, Mayans, O.
登録日2019-10-02
公開日2020-02-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献What does fluorine do to a protein? Thermodynamic, and highly-resolved structural insights into fluorine-labelled variants of the cold shock protein.
Sci Rep, 10, 2020

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