8CT0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ct0 by Molmil](/molmil-images/mine/8ct0) | |
6DXJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dxj by Molmil](/molmil-images/mine/6dxj) | |
6DWT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dwt by Molmil](/molmil-images/mine/6dwt) | |
6DY9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dy9 by Molmil](/molmil-images/mine/6dy9) | |
6DY5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dy5 by Molmil](/molmil-images/mine/6dy5) | |
6OW0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ow0 by Molmil](/molmil-images/mine/6ow0) | Crystal structure of mithramycin 3-side chain keto-reductase MtmW in complex with NAD+ and PEG | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, MtmW, ... | Authors: | Hou, C, Yu, X, Rohr, J, Tsodikov, O.V. | Deposit date: | 2019-05-08 | Release date: | 2019-11-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.67 Å) | Cite: | Discovery of a Cryptic Intermediate in Late Steps of Mithramycin Biosynthesis. Angew.Chem.Int.Ed.Engl., 59, 2020
|
|
6OVX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ovx by Molmil](/molmil-images/mine/6ovx) | Crystal structure of mithramycin 3-side chain keto-reductase MtmW in complex with NAD+, P422 form | Descriptor: | GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putative side chain reductase | Authors: | Hou, C, Yu, X, Rohr, J, Tsodikov, O.V. | Deposit date: | 2019-05-08 | Release date: | 2019-11-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Discovery of a Cryptic Intermediate in Late Steps of Mithramycin Biosynthesis. Angew.Chem.Int.Ed.Engl., 59, 2020
|
|
6OVQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ovq by Molmil](/molmil-images/mine/6ovq) | Crystal structure of mithramycin 3-side chain keto-reductase MtmW | Descriptor: | GLYCEROL, Putative Side chain reductase | Authors: | Hou, C, Yu, X, Rohr, J, Tsodikov, O.V. | Deposit date: | 2019-05-08 | Release date: | 2019-11-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Discovery of a Cryptic Intermediate in Late Steps of Mithramycin Biosynthesis. Angew.Chem.Int.Ed.Engl., 59, 2020
|
|
7JSL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7jsl by Molmil](/molmil-images/mine/7jsl) | |
7JSA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7jsa by Molmil](/molmil-images/mine/7jsa) | |
6VG2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vg2 by Molmil](/molmil-images/mine/6vg2) | |
6VGG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vgg by Molmil](/molmil-images/mine/6vgg) | Crystal structure of the DNA binding domains of human transcription factor ERG, human Runx2 bound to core binding factor beta (Cbfb), and mithramycin, in complex with 16mer DNA CAGAGGATGTGGCTTC | Descriptor: | Core-binding factor subunit beta, DNA (5'-D(P*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(P*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*TP*G)-3'), ... | Authors: | Hou, C, Rohr, J, Tsodikov, O.V. | Deposit date: | 2020-01-08 | Release date: | 2020-11-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (4.31 Å) | Cite: | Allosteric interference in oncogenic FLI1 and ERG transactions by mithramycins. Structure, 29, 2021
|
|
6VGD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vgd by Molmil](/molmil-images/mine/6vgd) | |
6VGE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vge by Molmil](/molmil-images/mine/6vge) | Crystal structure of the DNA binding domains of human transcription factor ERG, human Runx2 bound to core binding factor beta (Cbfb), in complex with 16mer DNA CAGAGGATGTGGCTTC | Descriptor: | Core-binding factor subunit beta, DNA (5'-D(P*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(P*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*TP*G)-3'), ... | Authors: | Hou, C, Tsodikov, O.V. | Deposit date: | 2020-01-07 | Release date: | 2020-11-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (4.25 Å) | Cite: | Allosteric interference in oncogenic FLI1 and ERG transactions by mithramycins. Structure, 29, 2021
|
|
6VG8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vg8 by Molmil](/molmil-images/mine/6vg8) | |
5JVT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5jvt by Molmil](/molmil-images/mine/5jvt) | |
5JVW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5jvw by Molmil](/molmil-images/mine/5jvw) | Crystal structure of mithramycin analogue MTM SA-Trp in complex with a 10-mer DNA AGAGGCCTCT. | Descriptor: | DNA (5'-D(*AP*GP*AP*GP*GP*CP*CP*TP*CP*T)-3'), Plicamycin, mithramycin analogue MTM SA-Trp, ... | Authors: | Hou, C, Rohr, J, Tsodikov, O.V. | Deposit date: | 2016-05-11 | Release date: | 2016-09-14 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of mithramycin analogues bound to DNA and implications for targeting transcription factor FLI1. Nucleic Acids Res., 44, 2016
|
|
7V0B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7v0b by Molmil](/molmil-images/mine/7v0b) | |
7V0D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7v0d by Molmil](/molmil-images/mine/7v0d) | Crystal structure of halogenase CtcP from Kitasatospora aureofaciens | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Hou, C, Tsodikov, O.V. | Deposit date: | 2022-05-10 | Release date: | 2023-05-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structures and complex formation of halogenase CtcP and FAD reductase CtcQ from the chlortetracycline biosynthetic pathway To Be Published
|
|
5JW2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5jw2 by Molmil](/molmil-images/mine/5jw2) | Crystal structure of mithramycin analogue MTM SA-Phe in complex with a 10-mer DNA AGGGATCCCT | Descriptor: | DNA (5'-D(*AP*GP*GP*GP*AP*TP*CP*CP*CP*T)-3'), Plicamycin, mithramycin analogue MTM SA-Phe, ... | Authors: | Hou, C, Rohr, J, Tsodikov, O.V. | Deposit date: | 2016-05-11 | Release date: | 2016-09-14 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structures of mithramycin analogues bound to DNA and implications for targeting transcription factor FLI1. Nucleic Acids Res., 44, 2016
|
|
7SXK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7sxk by Molmil](/molmil-images/mine/7sxk) | Kinetically trapped Pseudomonas-phage PaP3 portal protein - Full Length | Descriptor: | Portal protein | Authors: | Hou, C.F.D, Swanson, N.A, Li, F, Yang, R, Lokareddy, R.K, Cingolani, G. | Deposit date: | 2021-11-23 | Release date: | 2022-04-20 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM Structure of a Kinetically Trapped Dodecameric Portal Protein from the Pseudomonas-phage PaP3. J.Mol.Biol., 434, 2022
|
|
5JW0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5jw0 by Molmil](/molmil-images/mine/5jw0) | Crystal structure of mithramycin analogue MTM SA-Phe in complex with a 10-mer DNA AGGGTACCCT | Descriptor: | DNA (5'-D(P*AP*GP*GP*GP*TP*AP*CP*CP*CP*T)-3'), Plicamycin, mithramycin analogue MTM SA-Phe, ... | Authors: | Hou, C, Rohr, J, Tsodikov, O.V. | Deposit date: | 2016-05-11 | Release date: | 2016-09-14 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structures of mithramycin analogues bound to DNA and implications for targeting transcription factor FLI1. Nucleic Acids Res., 44, 2016
|
|
7SZ6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7sz6 by Molmil](/molmil-images/mine/7sz6) | Kinetically trapped Pseudomonas-phage PaP3 portal protein - delta barrel mutant class-3 | Descriptor: | Portal protein | Authors: | Hou, C.-F.D, Swanson, N.A, Li, F, Yang, R, Lokareddy, R.K, Cingolani, G. | Deposit date: | 2021-11-25 | Release date: | 2022-03-30 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (6.24 Å) | Cite: | Cryo-EM Structure of a Kinetically Trapped Dodecameric Portal Protein from the Pseudomonas-phage PaP3. J.Mol.Biol., 434, 2022
|
|
7SZ4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7sz4 by Molmil](/molmil-images/mine/7sz4) | Kinetically trapped Pseudomonas-phage PaP3 portal protein - delta barrel mutant class-2 | Descriptor: | Portal protein | Authors: | Hou, C.-F.D, Swanson, N.A, Li, F, Yang, R, Lokareddy, R.K, Cingolani, G. | Deposit date: | 2021-11-25 | Release date: | 2022-03-30 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Cryo-EM Structure of a Kinetically Trapped Dodecameric Portal Protein from the Pseudomonas-phage PaP3. J.Mol.Biol., 434, 2022
|
|
7SYA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7sya by Molmil](/molmil-images/mine/7sya) | Kinetically trapped Pseudomonas-phage PaP3 portal protein - Full Length | Descriptor: | Portal protein | Authors: | Hou, C.F.D, Swanson, N.A, Li, F, Yang, R, Lokareddy, R.K, Cingolani, G. | Deposit date: | 2021-11-24 | Release date: | 2022-04-20 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM Structure of a Kinetically Trapped Dodecameric Portal Protein from the Pseudomonas-phage PaP3. J.Mol.Biol., 434, 2022
|
|