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PDB: 8 results

4WUA
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BU of 4wua by Molmil
Crystal structure of human SRPK1 complexed to an inhibitor SRPIN340
Descriptor: CITRIC ACID, N-[2-(1-piperidinyl)-5-(trifluoromethyl)phenyl]-4-pyridinecarboxamide, SRSF protein kinase 1, ...
Authors:Hoshina, M, Ikura, T, Hosoya, T, Hagiwara, M, Ito, N.
Deposit date:2014-10-31
Release date:2015-09-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification of a Dual Inhibitor of SRPK1 and CK2 That Attenuates Pathological Angiogenesis of Macular Degeneration in Mice
Mol.Pharmacol., 88, 2015
3ANQ
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BU of 3anq by Molmil
human DYRK1A/inhibitor complex
Descriptor: (1Z)-1-(3-ethyl-5-hydroxy-1,3-benzothiazol-2(3H)-ylidene)propan-2-one, Dual specificity tyrosine-phosphorylation-regulated kinase 1A
Authors:Nonaka, Y, Hosoya, T, Hagiwara, M, Ito, N.
Deposit date:2010-09-06
Release date:2010-11-10
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A
Nat Commun, 1, 2010
3ANR
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BU of 3anr by Molmil
human DYRK1A/harmine complex
Descriptor: 7-METHOXY-1-METHYL-9H-BETA-CARBOLINE, Dual specificity tyrosine-phosphorylation-regulated kinase 1A
Authors:Nonaka, Y, Hosoya, T, Hagiwara, M, Ito, N.
Deposit date:2010-09-06
Release date:2010-11-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A
Nat Commun, 1, 2010
5ZAB
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BU of 5zab by Molmil
Crystal structure of cf3-aequorin
Descriptor: (2S)-8-benzyl-2-hydroperoxy-6-(4-hydroxyphenyl)-2-{[4-(trifluoromethyl)phenyl]methyl}imidazo[1,2-a]pyrazin-3(2H)-one, Aequorin-2
Authors:Inouye, S, Tomabechi, Y, Sekine, S.I, Shirouzu, M, Hosoya, T.
Deposit date:2018-02-07
Release date:2018-06-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.147 Å)
Cite:Slow luminescence kinetics of semi-synthetic aequorin: expression, purification and structure determination of cf3-aequorin.
J. Biochem., 164, 2018
7FHS
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BU of 7fhs by Molmil
Crystal structure of DYRK1A in complex with RD0392
Descriptor: (5~{Z})-5-[(3-ethoxy-4-oxidanyl-phenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one, Dual specificity tyrosine-phosphorylation-regulated kinase 1A, GLYCEROL
Authors:Kikuchi, M, Sumida, T, Hosoya, T, Kii, I, Umehara, T.
Deposit date:2021-07-30
Release date:2022-03-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structure-activity relationship for the folding intermediate-selective inhibition of DYRK1A.
Eur.J.Med.Chem., 227, 2022
7FHT
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BU of 7fht by Molmil
Crystal structure of DYRK1A in complex with RD0448
Descriptor: (5~{Z})-5-[(3-ethynyl-4-methoxy-phenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one, Dual specificity tyrosine-phosphorylation-regulated kinase 1A
Authors:Kikuchi, M, Sumida, Y, Hosoya, T, Kii, I, Umehara, T.
Deposit date:2021-07-30
Release date:2022-03-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Structure-activity relationship for the folding intermediate-selective inhibition of DYRK1A.
Eur.J.Med.Chem., 227, 2022
3U2J
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BU of 3u2j by Molmil
Neutron crystal structure of human Transthyretin
Descriptor: Transthyretin
Authors:Yokoyama, T, Mizuguchi, M, Nabeshima, Y, Kusaka, K, Yamada, T, Hosoya, T, Ohhara, T, Kurihara, K, Tomoyori, K, Tanaka, I, Niimura, N.
Deposit date:2011-10-03
Release date:2012-02-22
Last modified:2023-11-01
Method:NEUTRON DIFFRACTION (2 Å)
Cite:Hydrogen-bond network and pH sensitivity in transthyretin: Neutron crystal structure of human transthyretin
J.Struct.Biol., 177, 2012
3U2I
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BU of 3u2i by Molmil
X-ray crystal structure of human Transthyretin at room temperature
Descriptor: Transthyretin
Authors:Yokoyama, T, Mizuguchi, M, Nabeshima, Y, Kusaka, K, Yamada, T, Hosoya, T, Ohhara, T, Kurihara, K, Tomoyori, K, Tanaka, I, Niimura, N.
Deposit date:2011-10-03
Release date:2012-02-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Hydrogen-bond network and pH sensitivity in transthyretin: Neutron crystal structure of human transthyretin
J.Struct.Biol., 177, 2012

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數據於2024-10-30公開中

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