3ANR
human DYRK1A/harmine complex
Summary for 3ANR
Entry DOI | 10.2210/pdb3anr/pdb |
Related | 3ANQ |
Descriptor | Dual specificity tyrosine-phosphorylation-regulated kinase 1A, 7-METHOXY-1-METHYL-9H-BETA-CARBOLINE (3 entities in total) |
Functional Keywords | protein kinase, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus speckle: Q13627 |
Total number of polymer chains | 4 |
Total formula weight | 171464.96 |
Authors | Nonaka, Y.,Hosoya, T.,Hagiwara, M.,Ito, N. (deposition date: 2010-09-06, release date: 2010-11-10, Last modification date: 2011-07-13) |
Primary citation | Ogawa, Y.,Nonaka, Y.,Goto, T.,Ohnishi, E.,Hiramatsu, T.,Kii, I.,Yoshida, M.,Ikura, T.,Onogi, H.,Shibuya, H.,Hosoya, T.,Ito, N.,Hagiwara, M. Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A Nat Commun, 1:1-9, 2010 Cited by PubMed: 20981014DOI: 10.1038/ncomms1090 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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