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3ANQ

human DYRK1A/inhibitor complex

Summary for 3ANQ
Entry DOI10.2210/pdb3anq/pdb
Related3ANR
DescriptorDual specificity tyrosine-phosphorylation-regulated kinase 1A, (1Z)-1-(3-ethyl-5-hydroxy-1,3-benzothiazol-2(3H)-ylidene)propan-2-one (3 entities in total)
Functional Keywordsprotein kinase, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceHomo sapiens (human)
Cellular locationNucleus speckle: Q13627
Total number of polymer chains4
Total formula weight171557.18
Authors
Nonaka, Y.,Hosoya, T.,Hagiwara, M.,Ito, N. (deposition date: 2010-09-06, release date: 2010-11-10, Last modification date: 2023-11-15)
Primary citationOgawa, Y.,Nonaka, Y.,Goto, T.,Ohnishi, E.,Hiramatsu, T.,Kii, I.,Yoshida, M.,Ikura, T.,Onogi, H.,Shibuya, H.,Hosoya, T.,Ito, N.,Hagiwara, M.
Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A
Nat Commun, 1:1-9, 2010
Cited by
PubMed: 20981014
DOI: 10.1038/ncomms1090
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.6 Å)
Structure validation

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