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PDB: 12 件

6O15
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Crystal structure of a putative oxidoreductase YjhC from Escherichia coli in complex with NAD(H)
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, Uncharacterized oxidoreductase YjhC
著者Horne, C.R, Kind, L, Davies, J.S, Dobson, R.C.
登録日2019-02-17
公開日2019-11-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献On the structure and function of Escherichia coli YjhC: An oxidoreductase involved in bacterial sialic acid metabolism.
Proteins, 88, 2020
2B4M
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Crystal structure of the binding protein OpuAC in complex with proline betaine
分子名称: 1,1-DIMETHYL-PROLINIUM, Glycine betaine-binding protein
著者Horn, C, Sohn-Boesser, L, Breed, J, Welte, W, Schmitt, L, Bremer, E.
登録日2005-09-26
公開日2006-03-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular Determinants for Substrate Specificity of the Ligand-binding Protein OpuAC from Bacillus subtilis for the Compatible Solutes Glycine Betaine and Proline Betaine.
J.Mol.Biol., 357, 2006
2B4L
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Crystal structure of the binding protein OpuAC in complex with glycine betaine
分子名称: 1,2-ETHANEDIOL, Glycine betaine-binding protein, TRIMETHYL GLYCINE
著者Horn, C, Sohn-Boesser, L, Breed, J, Welte, W, Schmitt, L, Bremer, E.
登録日2005-09-26
公開日2006-03-21
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular Determinants for Substrate Specificity of the Ligand-binding Protein OpuAC from Bacillus subtilis for the Compatible Solutes Glycine Betaine and Proline Betaine.
J.Mol.Biol., 357, 2006
6ON4
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Crystal structure of the GntR-type sialoregulator NanR from Escherichia coli, in complex with sialic acid
分子名称: HTH-type transcriptional repressor NanR, N-acetyl-beta-neuraminic acid, ZINC ION, ...
著者Horne, C.R, Panjikar, S, North, R.A, Dobson, R.C.J.
登録日2019-04-19
公開日2020-07-08
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Control of the Escherichia coli sialoregulon by transcriptional repressor NanR.
J. Bacteriol., 195, 2013
6WFQ
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NanR dimer-DNA hetero-complex
分子名称: DNA (5'-D(P*GP*GP*TP*AP*TP*AP*AP*CP*AP*GP*GP*TP*AP*TP*A)-3'), DNA (5'-D(P*TP*AP*TP*AP*CP*CP*TP*GP*TP*TP*AP*TP*AP*CP*C)-3'), HTH-type transcriptional repressor NanR
著者Hariprasad, V, Horne, C, Santosh, P, Amy, H, Emre, B, Rachel, N, Michael, G, Georg, R, Borries, D, Renwick, D.
登録日2020-04-03
公開日2021-03-10
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism.
Nat Commun, 12, 2021
6WG7
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BU of 6wg7 by Molmil
Coordinates of NanR dimer fitted in Hexameric NanR-DNA hetero-complex cryo-EM map
分子名称: DNA (35-MER), HTH-type transcriptional repressor NanR
著者Hariprasad, V, Horne, C, Santosh, P, Amy, H, Emre, B, Rachel, N, Michael, G, Georg, R, Borries, D, Renwick, D.
登録日2020-04-05
公開日2021-03-10
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (8.3 Å)
主引用文献Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism.
Nat Commun, 12, 2021
2UZS
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BU of 2uzs by Molmil
A transforming mutation in the pleckstrin homology domain of AKT1 in cancer (AKT1-PH_E17K)
分子名称: INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, RAC-alpha serine/threonine-protein kinase
著者Carpten, J.D, Faber, A.L, Horn, C, Donoho, G.P, Briggs, S.L, Robbins, C.M, Hostetter, G, Boguslawski, S, Moses, T.Y, Savage, S, Uhlik, M, Lin, A, Du, J, Qian, Y.W, Zeckner, D.J, Tucker-Kellogg, G, Touchman, J, Patel, K, Mousses, S, Bittner, M, Schevitz, R, Lai, M.H, Blanchard, K.L, Thomas, J.E.
登録日2007-05-01
公開日2007-07-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献A transforming mutation in the pleckstrin homology domain of AKT1 in cancer.
Nature, 448, 2007
6VVG
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Structure of the Cydia pomonella Granulovirus kinase, PK-1
分子名称: ADENOSINE MONOPHOSPHATE, Arginine kinase
著者Oliver, M.R, Horne, C.R, Keown, J.R, Murphy, J.M, Metcalf, P.
登録日2020-02-17
公開日2021-02-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Granulovirus PK-1 kinase activity relies on a side-to-side dimerization mode centered on the regulatory alpha C helix.
Nat Commun, 12, 2021
2UZR
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A transforming mutation in the pleckstrin homology domain of AKT1 in cancer (AKT1-PH_E17K)
分子名称: RAC-alpha serine/threonine-protein kinase
著者Carpten, J.D, Faber, A.L, Horn, C, Donoho, G.P, Briggs, S.L, Robbins, C.M, Hostetter, G, Boguslawski, S, Moses, T.Y, Savage, S, Uhlik, M, Lin, A, Du, J, Qian, Y.W, Zeckner, D.J, Tucker-Kellogg, G, Touchman, J, Patel, K, Mousses, S, Bittner, M, Schevitz, R, Lai, M.H, Blanchard, K.L, Thomas, J.E.
登録日2007-05-01
公開日2007-07-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献A transforming mutation in the pleckstrin homology domain of AKT1 in cancer.
Nature, 448, 2007
6Q28
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Metal ROK rebel: Characterisation of N-acetylmannosamine kinase from the pathogen Staphylococcus aureus
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetylmannosamine kinase
著者Coombes, D, Horne, C.R, Dobson, R.C.J.
登録日2019-08-07
公開日2020-01-22
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The basis for non-canonical ROK family function in theN-acetylmannosamine kinase from the pathogenStaphylococcus aureus.
J.Biol.Chem., 295, 2020
6Q27
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N-acetylmannosamine kinase with N-acetylmannosamine from Staphylococcus aureus
分子名称: 2-acetamido-2-deoxy-alpha-D-mannopyranose, Glucokinase
著者Coombes, D, Horne, C.R, Davies, J.S, Dobson, R.C.J.
登録日2019-08-07
公開日2020-01-22
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The basis for non-canonical ROK family function in theN-acetylmannosamine kinase from the pathogenStaphylococcus aureus.
J.Biol.Chem., 295, 2020
6E8L
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Crystal Structure of Alkyl hydroperoxidase D (AhpD) from Streptococcus pneumoniae (Strain D39/ NCTC 7466)
分子名称: Alkyl hydroperoxide reductase AhpD
著者Meng, Y, Davies, J, North, R, Coombes, D, Horne, C, Hampton, M, Dobson, R.
登録日2018-07-30
公開日2019-08-28
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure-function analyses of alkylhydroperoxidase D fromStreptococcus pneumoniaereveal an unusual three-cysteine active site architecture.
J.Biol.Chem., 295, 2020

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件を2024-05-15に公開中

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