6QV5
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5LPZ
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5LPW
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2PE8
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3BXJ
| Crystal Structure of the C2-GAP Fragment of synGAP | Descriptor: | Ras GTPase-activating protein SynGAP | Authors: | Pena, V, Hothorn, M, Eberth, A, Kaschau, N, Parret, A, Gremer, L, Bonneau, F, Ahmadian, M.R, Scheffzek, K. | Deposit date: | 2008-01-14 | Release date: | 2008-03-25 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The C2 domain of SynGAP is essential for stimulation of the Rap GTPase reaction. Embo Rep., 9, 2008
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3CB5
| Crystal Structure of the S. pombe Peptidase Homology Domain of FACT complex subunit Spt16 (form A) | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FACT complex subunit spt16 | Authors: | Stuwe, T, Hothorn, M, Lejeune, E, Bortfeld-Miller, M, Scheffzek, K, Ladurner, A.G. | Deposit date: | 2008-02-21 | Release date: | 2008-06-17 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | The FACT Spt16 "peptidase" domain is a histone H3-H4 binding module Proc.Natl.Acad.Sci.USA, 105, 2008
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5A61
| Crystal structure of full-length E. coli ygiF in complex with tripolyphosphate and two manganese ions. | Descriptor: | 1,2-ETHANEDIOL, INORGANIC TRIPHOSPHATASE, MANGANESE (II) ION, ... | Authors: | Martinez, J, Truffault, V, Hothorn, M. | Deposit date: | 2015-06-23 | Release date: | 2015-08-05 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural Determinants for Substrate Binding and Catalysis in Triphosphate Tunnel Metalloenzymes. J.Biol.Chem., 290, 2015
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5A68
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4NHG
| Crystal Structure of 2G12 IgG Dimer | Descriptor: | 2G12 IgG dimer heavy chain, 2G12 IgG dimer light chain, Hepatitis B virus receptor binding protein | Authors: | Wu, Y, West Jr, A.P, Kim, H.J, Thornton, M.E, Ward, A.B, Bjorkman, P.J. | Deposit date: | 2013-11-05 | Release date: | 2014-02-26 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (8.001 Å) | Cite: | Structural basis for enhanced HIV-1 neutralization by a dimeric immunoglobulin G form of the glycan-recognizing antibody 2G12. Cell Rep, 5, 2013
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3G3T
| Crystal structure of a eukaryotic polyphosphate polymerase in complex with orthophosphate | Descriptor: | 1,2-ETHANEDIOL, PHOSPHATE ION, Vacuolar transporter chaperone 4 | Authors: | Lenherr, E.D, Hothorn, M, Scheffzek, K. | Deposit date: | 2009-02-02 | Release date: | 2009-05-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Catalytic core of a membrane-associated eukaryotic polyphosphate polymerase. Science, 324, 2009
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3E0P
| The X-ray structure of Human Prostasin in complex with a covalent benzoxazole inhibitor | Descriptor: | GLYCEROL, Prostasin, benzyl [(1R)-1-({(2S,4R)-2-({(1S)-5-amino-1-[(S)-1,3-benzoxazol-2-yl(hydroxy)methyl]pentyl}carbamoyl)-4-[(4-methylbenzyl)oxy]pyrrolidin-1-yl}carbonyl)-3-phenylpropyl]carbamate | Authors: | Spraggon, G, Hornsby, M, Shipway, A, Harris, J.L, Lesley, S.A. | Deposit date: | 2008-07-31 | Release date: | 2008-09-09 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Discovery of inhibitors of the channel-activating protease prostasin (CAP1/PRSS8) utilizing structure-based design. Bioorg.Med.Chem.Lett., 18, 2008
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5A60
| Crystal structure of full-length E. coli ygiF in complex with tripolyphosphate and two magnesium ions | Descriptor: | 1,2-ETHANEDIOL, INORGANIC TRIPHOSPHATASE, MAGNESIUM ION, ... | Authors: | Martinez, J, Truffault, V, Hothorn, M. | Deposit date: | 2015-06-23 | Release date: | 2015-08-05 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Structural Determinants for Substrate Binding and Catalysis in Triphosphate Tunnel Metalloenzymes. J.Biol.Chem., 290, 2015
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5A64
| Crystal structure of mouse thiamine triphosphatase in complex with thiamine triphosphate. | Descriptor: | 1,2-ETHANEDIOL, THIAMINE TRIPHOSPHATASE, TRIETHYLENE GLYCOL, ... | Authors: | Martinez, J, Truffault, V, Hothorn, M. | Deposit date: | 2015-06-24 | Release date: | 2015-08-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Determinants for Substrate Binding and Catalysis in Triphosphate Tunnel Metalloenzymes. J.Biol.Chem., 290, 2015
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3DXB
| Structure of the UHM domain of Puf60 fused to thioredoxin | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, thioredoxin N-terminally fused to Puf60(UHM) | Authors: | Corsini, L, Hothorn, M, Scheffzek, K, Stier, G, Sattler, M. | Deposit date: | 2008-07-24 | Release date: | 2008-10-28 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Dimerization and Protein Binding Specificity of the U2AF Homology Motif of the Splicing Factor Puf60. J.Biol.Chem., 284, 2009
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3E16
| X-ray structure of human prostasin in complex with Benzoxazole warhead peptidomimic, lysine in P3 | Descriptor: | DIMETHYL SULFOXIDE, GLYCEROL, Prostasin, ... | Authors: | Spraggon, G, Hornsby, M, Shipway, A, Harris, J.L, Lesley, S.A. | Deposit date: | 2008-08-01 | Release date: | 2008-09-09 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Discovery of inhibitors of the channel-activating protease prostasin (CAP1/PRSS8) utilizing structure-based design. Bioorg.Med.Chem.Lett., 18, 2008
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2PEH
| Crystal structure of the UHM domain of human SPF45 in complex with SF3b155-ULM5 | Descriptor: | Splicing factor 3B subunit 1, Splicing factor 45 | Authors: | Corsini, L, Basquin, J, Hothorn, M, Sattler, M. | Deposit date: | 2007-04-03 | Release date: | 2007-06-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | U2AF-homology motif interactions are required for alternative splicing regulation by SPF45. Nat.Struct.Mol.Biol., 14, 2007
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4LSX
| Plant steroid receptor ectodomain bound to brassinolide and SERK1 co-receptor ectodomain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Brassinolide, ... | Authors: | Santiago, J, Henzler, C, Hothorn, M. | Deposit date: | 2013-07-23 | Release date: | 2013-09-04 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.302 Å) | Cite: | Molecular mechanism for plant steroid receptor activation by somatic embryogenesis co-receptor kinases. Science, 341, 2013
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4NHH
| Structure of 2G12 IgG Dimer | Descriptor: | 2G12 IgG dimer heavy chain, 2G12 IgG dimer light chain, Hepatitis B virus receptor binding protein | Authors: | Wu, Y, West Jr, A.P, Kim, H.J, Thornton, M.E, Ward, A.B, Bjorkman, P.J. | Deposit date: | 2013-11-05 | Release date: | 2014-02-26 | Method: | X-RAY DIFFRACTION (6.5 Å) | Cite: | Structural basis for enhanced HIV-1 neutralization by a dimeric immunoglobulin G form of the glycan-recognizing antibody 2G12. Cell Rep, 5, 2013
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6QVA
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6R1H
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2XNR
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2XNQ
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5IJH
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5IIQ
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5IJJ
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