1TGO
 
 | | THERMOSTABLE B TYPE DNA POLYMERASE FROM THERMOCOCCUS GORGONARIUS | | 分子名称: | PROTEIN (THERMOSTABLE B DNA POLYMERASE) | | 著者 | Hopfner, K.-P, Eichinger, A, Engh, R.A, Laue, F, Ankenbauer, W, Huber, R, Angerer, B. | | 登録日 | 1999-02-23 | | 公開日 | 1999-03-22 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of a thermostable type B DNA polymerase from Thermococcus gorgonarius.
Proc.Natl.Acad.Sci.USA, 96, 1999
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1RFN
 | | HUMAN COAGULATION FACTOR IXA IN COMPLEX WITH P-AMINO BENZAMIDINE | | 分子名称: | CALCIUM ION, P-AMINO BENZAMIDINE, PROTEIN (COAGULATION FACTOR IX), ... | | 著者 | Hopfner, K.-P, Lang, A, Karcher, A, Sichler, K, Kopetzki, E, Brandstetter, H, Huber, R, Bode, W, Engh, R.A. | | 登録日 | 1999-04-19 | | 公開日 | 1999-09-01 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Coagulation factor IXa: the relaxed conformation of Tyr99 blocks substrate binding.
Structure Fold.Des., 7, 1999
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1II7
 | | Crystal structure of P. furiosus Mre11 with manganese and dAMP | | 分子名称: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, MANGANESE (II) ION, Mre11 nuclease, ... | | 著者 | Hopfner, K.-P, Karcher, A, Craig, L, Woo, T.T, Carney, J.P, Tainer, J.A. | | 登録日 | 2001-04-20 | | 公開日 | 2001-05-30 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase.
Cell(Cambridge,Mass.), 105, 2001
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1II8
 | | Crystal structure of the P. furiosus Rad50 ATPase domain | | 分子名称: | PHOSPHATE ION, Rad50 ABC-ATPase | | 著者 | Hopfner, K.-P, Karcher, A, Craig, L, Woo, T.T, Carney, J.P, Tainer, J.A. | | 登録日 | 2001-04-20 | | 公開日 | 2001-05-30 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (3.02 Å) | | 主引用文献 | Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase.
Cell(Cambridge,Mass.), 105, 2001
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3PP4
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3PP3
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4WVY
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3EIK
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5DAC
 | | ATP-gamma-S bound Rad50 from Chaetomium thermophilum in complex with DNA | | 分子名称: | 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*C)-3'), DNA (5'-D(P*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*G)-3'), ... | | 著者 | Seifert, F.U, Lammens, K, Stoehr, G, Kessler, B, Hopfner, K.-P. | | 登録日 | 2015-08-19 | | 公開日 | 2016-03-02 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.503 Å) | | 主引用文献 | Structural mechanism of ATP-dependent DNA binding and DNA end bridging by eukaryotic Rad50.
Embo J., 35, 2016
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2B2N
 | | Structure of transcription-repair coupling factor | | 分子名称: | O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL, SODIUM ION, SULFATE ION, ... | | 著者 | Assenmacher, N, Wenig, K, Lammens, A, Hopfner, K.-P. | | 登録日 | 2005-09-19 | | 公開日 | 2006-01-24 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural Basis for Transcription-coupled Repair: the N Terminus of Mfd Resembles UvrB with Degenerate ATPase Motifs
J.Mol.Biol., 355, 2006
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3G9A
 | | Green fluorescent protein bound to minimizer nanobody | | 分子名称: | Green fluorescent protein, Minimizer | | 著者 | Kirchhofer, A, Helma, J, Schmidthals, K, Frauer, C, Cui, S, Karcher, A, Pellis, M, Muyldermans, S, Delucci, C.C, Cardoso, M.C, Leonhardt, H, Hopfner, K.-P, Rothbauer, U. | | 登録日 | 2009-02-13 | | 公開日 | 2009-12-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.614 Å) | | 主引用文献 | Modulation of protein properties in living cells using nanobodies
Nat.Struct.Mol.Biol., 17, 2010
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5N6I
 | | Crystal structure of mouse cGAS in complex with 39 bp DNA | | 分子名称: | Cyclic GMP-AMP synthase, DNA (36-MER), DNA (37-MER), ... | | 著者 | Andreeva, L, Kostrewa, D, Hopfner, K.-P. | | 登録日 | 2017-02-15 | | 公開日 | 2017-09-13 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders.
Nature, 549, 2017
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7ZKE
 | | Mot1:TBP:DNA - pre-hydrolysis state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (36-MER), ... | | 著者 | Woike, S, Eustermann, S, Jung, J, Wenzl, S.J, Hagemann, G, Bartho, J.D, Lammens, K, Butryn, A, Herzog, F, Hopfner, K.-P. | | 登録日 | 2022-04-12 | | 公開日 | 2023-04-26 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural basis for TBP displacement from TATA box DNA by the Swi2/Snf2 ATPase Mot1.
Nat.Struct.Mol.Biol., 30, 2023
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3L51
 | | Crystal Structure of the Mouse Condensin Hinge Domain | | 分子名称: | GLYCEROL, Structural maintenance of chromosomes protein 2, Structural maintenance of chromosomes protein 4 | | 著者 | Griese, J.J, Hopfner, K.-P. | | 登録日 | 2009-12-21 | | 公開日 | 2010-02-16 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.506 Å) | | 主引用文献 | Structure and DNA binding activity of the mouse condensin hinge domain highlight common and diverse features of SMC proteins
Nucleic Acids Res., 38, 2010
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3K1K
 | | Green fluorescent protein bound to enhancer nanobody | | 分子名称: | Enhancer, Green Fluorescent Protein | | 著者 | Kirchhofer, A, Helma, J, Schmidthals, K, Frauer, C, Cui, S, Karcher, A, Pellis, M, Muyldermans, S, Delucci, C.C, Cardoso, M.C, Leonhardt, H, Hopfner, K.-P, Rothbauer, U. | | 登録日 | 2009-09-28 | | 公開日 | 2009-12-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Modulation of protein properties in living cells using nanobodies
Nat.Struct.Mol.Biol., 17, 2010
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3M85
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3M7N
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4KB6
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4IMK
 | | Uncrossed Fab binding to human Angiopoietin 2 | | 分子名称: | GLYCEROL, Heavy Chain, Light Chain, ... | | 著者 | Fenn, S, Schiller, C, Griese, J.J, Hopfner, K.-P, Kettenberger, H. | | 登録日 | 2013-01-03 | | 公開日 | 2013-04-17 | | 最終更新日 | 2013-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.202 Å) | | 主引用文献 | Crystal Structure of an Anti-Ang2 CrossFab Demonstrates Complete Structural and Functional Integrity of the Variable Domain.
Plos One, 8, 2013
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4IML
 | | CrossFab binding to human Angiopoietin 2 | | 分子名称: | Crossed heavy chain (VH-Ckappa), Crossed light chain (VL-CH1), GLYCEROL | | 著者 | Fenn, S, Schiller, C, Griese, J, Hopfner, K.-P, Kettenberger, H. | | 登録日 | 2013-01-03 | | 公開日 | 2013-04-17 | | 最終更新日 | 2013-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.931 Å) | | 主引用文献 | Crystal Structure of an Anti-Ang2 CrossFab Demonstrates Complete Structural and Functional Integrity of the Variable Domain.
Plos One, 8, 2013
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3TJ1
 | | Crystal Structure of RNA Polymerase I Transcription Initiation Factor Rrn3 | | 分子名称: | RNA polymerase I-specific transcription initiation factor RRN3 | | 著者 | Blattner, C, Jennebach, S, Herzog, F, Mayer, A, Cheung, A.C.M, Witte, G, Lorenzen, K, Hopfner, K.-P, Heck, A.J.R, Aebersold, R, Cramer, P. | | 登録日 | 2011-08-23 | | 公開日 | 2011-09-28 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Molecular basis of Rrn3-regulated RNA polymerase I initiation and cell growth.
Genes Dev., 25, 2011
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3TBK
 | | Mouse RIG-I ATPase Domain | | 分子名称: | 1,2-ETHANEDIOL, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, RIG-I Helicase Domain | | 著者 | Civril, F, Bennett, M.D, Hopfner, K.-P. | | 登録日 | 2011-08-07 | | 公開日 | 2011-10-26 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | The RIG-I ATPase domain structure reveals insights into ATP-dependent antiviral signalling.
Embo Rep., 12, 2011
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5EOM
 | | Structure of full-length human MAB21L1 with bound CTP | | 分子名称: | CITRIC ACID, CYTIDINE-5'-TRIPHOSPHATE, Protein mab-21-like 1, ... | | 著者 | de Oliveira Mann, C.C, Witte, G, Hopfner, K.-P. | | 登録日 | 2015-11-10 | | 公開日 | 2016-06-01 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Structural and biochemical characterization of the cell fate determining nucleotidyltransferase fold protein MAB21L1.
Sci Rep, 6, 2016
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5EOG
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6G7E
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