6YJ4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6yj4 by Molmil](/molmil-images/mine/6yj4) | Structure of Yarrowia lipolytica complex I at 2.7 A | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Acyl carrier protein ACPM1 of NADH:Ubiquinone Oxidoreductase (Complex I), Acyl carrier protein ACPM2 of NADH:Ubiquinone Oxidoreductase (Complex I), ... | Authors: | Hirst, J, Grba, D. | Deposit date: | 2020-04-02 | Release date: | 2020-08-12 | Last modified: | 2021-03-17 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Mitochondrial complex I structure reveals ordered water molecules for catalysis and proton translocation. Nat.Struct.Mol.Biol., 27, 2020
|
|
6YJ5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6yj5 by Molmil](/molmil-images/mine/6yj5) | |
7B0N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7b0n by Molmil](/molmil-images/mine/7b0n) | |
1DSP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1dsp by Molmil](/molmil-images/mine/1dsp) | CYTOCHROME C PEROXIDASE H175G MUTANT, IMIDAZOLE COMPLEX AT PH 7, ROOM TEMPERATURE. | Descriptor: | CYTOCHROME C PEROXIDASE, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Hirst, J, Wilcox, S.K, Williams, P.A, McRee, D.E, Goodin, D.B. | Deposit date: | 2000-01-07 | Release date: | 2001-03-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Replacement of the axial histidine ligand with imidazole in cytochrome c peroxidase. 1. Effects on structure. Biochemistry, 40, 2001
|
|
1DSG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1dsg by Molmil](/molmil-images/mine/1dsg) | CYTOCHROME C PEROXIDASE H175G MUTANT, IMIDAZOLE COMPLEX AT PH 5, ROOM TEMPERATURE. | Descriptor: | CYTOCHROME C PEROXIDASE, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Hirst, J, Wilcox, S.K, Williams, P.A, McRee, D.E, Goodin, D.B. | Deposit date: | 2000-01-07 | Release date: | 2001-03-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.56 Å) | Cite: | Replacement of the axial histidine ligand with imidazole in cytochrome c peroxidase. 1. Effects on structure. Biochemistry, 40, 2001
|
|
1DSE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1dse by Molmil](/molmil-images/mine/1dse) | CYTOCHROME C PEROXIDASE H175G MUTANT, IMIDAZOLE COMPLEX, WITH PHOSPHATE BOUND, PH 6, 100K | Descriptor: | CYTOCHROME C PEROXIDASE, IMIDAZOLE, PHOSPHATE ION, ... | Authors: | Hirst, J, Wilcox, S.K, Williams, P.A, McRee, D.E, Goodin, D.B. | Deposit date: | 2000-01-07 | Release date: | 2001-03-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Replacement of the axial histidine ligand with imidazole in cytochrome c peroxidase. 1. Effects on structure. Biochemistry, 40, 2001
|
|
1DS4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ds4 by Molmil](/molmil-images/mine/1ds4) | CYTOCHROME C PEROXIDASE H175G MUTANT, IMIDAZOLE COMPLEX, PH 6, 100K | Descriptor: | CYTOCHROME C PEROXIDASE, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Hirst, J, Wilcox, S.K, Williams, P.A, McRee, D.E, Goodin, D.B. | Deposit date: | 2000-01-07 | Release date: | 2001-03-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Replacement of the axial histidine ligand with imidazole in cytochrome c peroxidase. 1. Effects on structure. Biochemistry, 40, 2001
|
|
1DSO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1dso by Molmil](/molmil-images/mine/1dso) | CYTOCHROME C PEROXIDASE H175G MUTANT, IMIDAZOLE COMPLEX AT PH 6, ROOM TEMPERATURE. | Descriptor: | CYTOCHROME C PEROXIDASE, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Hirst, J, Wilcox, S.K, Williams, P.A, McRee, D.E, Goodin, D.B. | Deposit date: | 2000-01-07 | Release date: | 2001-03-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Replacement of the axial histidine ligand with imidazole in cytochrome c peroxidase. 1. Effects on structure. Biochemistry, 40, 2001
|
|
1DJ1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1dj1 by Molmil](/molmil-images/mine/1dj1) | CRYSTAL STRUCTURE OF R48A MUTANT OF CYTOCHROME C PEROXIDASE | Descriptor: | CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Hirst, J, Goodin, D.B. | Deposit date: | 1999-11-30 | Release date: | 1999-12-10 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Unusual oxidative chemistry of N(omega)-hydroxyarginine and N-hydroxyguanidine catalyzed at an engineered cavity in a heme peroxidase. J.Biol.Chem., 275, 2000
|
|
1DJ5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1dj5 by Molmil](/molmil-images/mine/1dj5) | |
5COD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5cod by Molmil](/molmil-images/mine/5cod) | Bovine heart complex I membrane domain | Descriptor: | NADH-ubiquinone oxidoreductase chain 4, NADH-ubiquinone oxidoreductase chain 5, SDAP, ... | Authors: | Zhu, J, Hirst, J, King, M.S, Yu, M, Leslie, A.G.W, Klipcan, L. | Deposit date: | 2015-07-20 | Release date: | 2015-09-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (6.74 Å) | Cite: | Structure of subcomplex I beta of mammalian respiratory complex I leads to new supernumerary subunit assignments. Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
4UQ8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4uq8 by Molmil](/molmil-images/mine/4uq8) | Electron cryo-microscopy of bovine Complex I | Descriptor: | ACYL CARRIER PROTEIN, MITOCHONDRIAL, FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Vinothkumar, K.R, Zhu, J, Hirst, J. | Deposit date: | 2014-06-21 | Release date: | 2014-10-01 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.95 Å) | Cite: | Architecture of Mammalian Respiratory Complex I. Nature, 515, 2014
|
|
5O31
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5o31 by Molmil](/molmil-images/mine/5o31) | Mitochondrial complex I in the deactive state | Descriptor: | Acyl carrier protein, mitochondrial, FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Blaza, J.N, Vinothkumar, K.R, Hirst, J. | Deposit date: | 2017-05-23 | Release date: | 2018-01-17 | Last modified: | 2019-10-23 | Method: | ELECTRON MICROSCOPY (4.13 Å) | Cite: | Structure of the Deactive State of Mammalian Respiratory Complex I. Structure, 26, 2018
|
|
2V07
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2v07 by Molmil](/molmil-images/mine/2v07) | Structure of the Arabidopsis thaliana cytochrome c6A V52Q variant | Descriptor: | CYTOCHROME C6, HEME C | Authors: | Worrall, J.A.R, Schlarb-Ridley, B.G, Reda, T, Marcaida, M.J, Moorlen, R.J, Wastl, J, Hirst, J, Bendall, D.S, Luisi, B.F, Howe, C.J. | Deposit date: | 2007-05-09 | Release date: | 2007-07-24 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Modulation of heme redox potential in the cytochrome c6 family. J. Am. Chem. Soc., 129, 2007
|
|
2V08
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2v08 by Molmil](/molmil-images/mine/2v08) | Structure of wild-type Phormidium laminosum cytochrome c6 | Descriptor: | CHLORIDE ION, CYTOCHROME C6, HEME C, ... | Authors: | Worrall, J.A.R, Schlarb-Ridley, B.G, Reda, T, Marcaida, M.J, Moorlen, R.J, Wastl, J, Hirst, J, Bendall, D.S, Luisi, B.F, Howe, C.J. | Deposit date: | 2007-05-10 | Release date: | 2007-07-24 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Modulation of heme redox potential in the cytochrome c6 family. J. Am. Chem. Soc., 129, 2007
|
|
7R4D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7r4d by Molmil](/molmil-images/mine/7r4d) | Bovine complex I in the presence of IM1761092, deactive class vi (Composite map) | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | Authors: | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | Deposit date: | 2022-02-08 | Release date: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
|
|
7R42
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7r42 by Molmil](/molmil-images/mine/7r42) | Bovine complex I in the presence of IM1761092, active class ii (Composite map) | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | Authors: | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | Deposit date: | 2022-02-08 | Release date: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
|
|
7R41
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7r41 by Molmil](/molmil-images/mine/7r41) | Bovine complex I in the presence of IM1761092, active class i (Composite map) | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | Authors: | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | Deposit date: | 2022-02-08 | Release date: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
|
|
7R44
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7r44 by Molmil](/molmil-images/mine/7r44) | Bovine complex I in the presence of IM1761092, active class iv (Composite map) | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | Authors: | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | Deposit date: | 2022-02-08 | Release date: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
|
|
7R45
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7r45 by Molmil](/molmil-images/mine/7r45) | Bovine complex I in the presence of IM1761092, deactive class i (Composite map) | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | Authors: | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | Deposit date: | 2022-02-08 | Release date: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
|
|
7R46
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7r46 by Molmil](/molmil-images/mine/7r46) | Bovine complex I in the presence of IM1761092, deactive class ii (Composite map) | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | Authors: | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | Deposit date: | 2022-02-08 | Release date: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
|
|
7R43
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7r43 by Molmil](/molmil-images/mine/7r43) | Bovine complex I in the presence of IM1761092, active class iii (Composite map) | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | Authors: | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | Deposit date: | 2022-02-08 | Release date: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
|
|
7R48
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7r48 by Molmil](/molmil-images/mine/7r48) | Bovine complex I in the presence of IM1761092, deactive class iv (Composite map) | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | Authors: | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | Deposit date: | 2022-02-08 | Release date: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
|
|
7R47
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7r47 by Molmil](/molmil-images/mine/7r47) | Bovine complex I in the presence of IM1761092, deactive class iii (Composite map) | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | Authors: | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | Deposit date: | 2022-02-08 | Release date: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
|
|
7R4C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7r4c by Molmil](/molmil-images/mine/7r4c) | Bovine complex I in the presence of IM1761092, deactive class v (Composite map) | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | Authors: | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | Deposit date: | 2022-02-08 | Release date: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
|
|