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PDB: 37 results

1QBH
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SOLUTION STRUCTURE OF A BACULOVIRAL INHIBITOR OF APOPTOSIS (IAP) REPEAT
Descriptor: INHIBITOR OF APOPTOSIS PROTEIN (2MIHB/C-IAP-1), ZINC ION
Authors:Hinds, M.G, Norton, R.S, Vaux, D.L, Day, C.L.
Deposit date:1999-04-20
Release date:1999-10-20
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of a baculoviral inhibitor of apoptosis (IAP) repeat.
Nat.Struct.Biol., 6, 1999
1A7M
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LEUKAEMIA INHIBITORY FACTOR CHIMERA (MH35-LIF), NMR, 20 STRUCTURES
Descriptor: LEUKEMIA INHIBITORY FACTOR
Authors:Hinds, M.G, Maurer, T, Zhang, J.-G, Nicola, N.A, Norton, R.S.
Deposit date:1998-03-16
Release date:1999-04-20
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:Solution structure of leukemia inhibitory factor.
J.Biol.Chem., 273, 1998
1KD6
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Solution structure of the eukaryotic pore-forming cytolysin equinatoxin II
Descriptor: EQUINATOXIN II
Authors:Hinds, M.G, Zhang, W, Anderluh, G, Hansen, P.E, Norton, R.S.
Deposit date:2001-11-12
Release date:2002-02-13
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the eukaryotic pore-forming cytolysin equinatoxin II: implications for pore formation.
J.Mol.Biol., 315, 2002
1O0L
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THE STRUCTURE OF BCL-W REVEALS A ROLE FOR THE C-TERMINAL RESIDUES IN MODULATING BIOLOGICAL ACTIVITY
Descriptor: Apoptosis regulator Bcl-W
Authors:Hinds, M.G, Lackmann, M, Skea, G.L, Harrison, P.J, Huang, D.C.S, Day, C.L.
Deposit date:2003-02-22
Release date:2003-04-01
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The structure of Bcl-w reveals a role for the C-terminal residues in modulating biological activity
Embo J., 22, 2003
6TZC
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Crystal Structure of African Swine Fever Virus A179L with the Autophagy Regulator Beclin
Descriptor: Apoptosis regulator Bcl-2 homolog, Beclin-1, Maltose/maltodextrin-binding periplasmic protein, ...
Authors:Banjara, S, Kvansakul, M, Hinds, M.G.
Deposit date:2019-08-12
Release date:2019-11-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Crystal Structure of African Swine Fever Virus A179L with the Autophagy Regulator Beclin.
Viruses, 11, 2019
4B4S
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Crystal Structure of a pro-survival Bcl-2:Bim BH3 complex
Descriptor: BCL-2-LIKE PROTEIN 10, BCL-2-LIKE PROTEIN 11, TETRAETHYLENE GLYCOL
Authors:Rautureau, G.J.P, Hinds, M.G, Kvansakul, M.
Deposit date:2012-08-01
Release date:2013-01-16
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Restricted Binding Repertoire of Bcl-B Leaves Bim as the Universal Bh3-Only Prosurvival Bcl-2 Protein Antagonist.
Cell Death Dis., 3, 2012
7QTX
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Kaposi sarcoma associated herpes virus (KSHV) encoded apoptosis inhibitor, KsBcl-2 in complex with Puma BH3
Descriptor: 1,2-ETHANEDIOL, BROMIDE ION, Bcl-2, ...
Authors:Suraweera, C.D, Hinds, M.G, Kvansakul, M.
Deposit date:2022-01-17
Release date:2022-11-23
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.11598849 Å)
Cite:Structural Insight into KsBcl-2 Mediated Apoptosis Inhibition by Kaposi Sarcoma Associated Herpes Virus.
Viruses, 14, 2022
7QTW
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Kaposi sarcoma associated herpes virus(KSHV) encoded apoptosis inhibitor, KsBcl-2 in complex with Bid BH3
Descriptor: 1,2-ETHANEDIOL, BH3-interacting domain death agonist p15, Bcl-2
Authors:Suraweera, C.D, Hinds, M.G, Kvansakul, M.
Deposit date:2022-01-17
Release date:2022-11-23
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Structural Insight into KsBcl-2 Mediated Apoptosis Inhibition by Kaposi Sarcoma Associated Herpes Virus.
Viruses, 14, 2022
7ADT
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Orf virus Apoptosis inhibitor ORFV125
Descriptor: 1,2-ETHANEDIOL, Apoptosis inhibitor, Apoptosis regulator BAX, ...
Authors:Suraweera, C.D, Hinds, M.G, Kvansakul, M.
Deposit date:2020-09-16
Release date:2021-10-06
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.210037 Å)
Cite:Crystal structures of ORFV125 provide insight into orf virus-mediated inhibition of apoptosis.
Biochem.J., 477, 2020
7ADS
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Orf virus Apoptosis inhibitor ORFV125
Descriptor: 1,2-ETHANEDIOL, Apoptosis inhibitor, CHLORIDE ION, ...
Authors:Suraweera, C.D, Hinds, M.G, Kvansakul, M.
Deposit date:2020-09-16
Release date:2021-10-06
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.22032046 Å)
Cite:Crystal structures of ORFV125 provide insight into orf virus-mediated inhibition of apoptosis.
Biochem.J., 477, 2020
5TWA
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Crystal structure of Geodia cydonium BHP2 in complex with Lubomirskia baicalensis Bak-2
Descriptor: 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BAK-2 protein, ...
Authors:Caria, S, Hinds, M.G, Kvansakul, M.
Deposit date:2016-11-12
Release date:2017-01-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural insight into an evolutionarily ancient programmed cell death regulator - the crystal structure of marine sponge BHP2 bound to LB-Bak-2.
Cell Death Dis, 8, 2017
6FBX
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Crystal Structure of a Zebra-fish pro-survival protein NRZ:Bad BH3 complex
Descriptor: BCL2-antagonist of cell death, BCL2-like 10
Authors:Suraweera, C.D, Hinds, M.G, Kvansakul, M.
Deposit date:2017-12-20
Release date:2019-03-27
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.639 Å)
Cite:A structural investigation of NRZ mediated apoptosis regulation in zebrafish.
Cell Death Dis, 9, 2018
6H1N
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Crystal Structure of a Zebra-fish pro-survival protein NRZ-apo
Descriptor: ACETATE ION, BCL2-like 10 (Apoptosis facilitator), SULFATE ION
Authors:Suraweera, C.D, Hinds, M.G, Kvansakul, M.
Deposit date:2018-07-12
Release date:2018-10-03
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:A structural investigation of NRZ mediated apoptosis regulation in zebrafish.
Cell Death Dis, 9, 2018
7P0U
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ORF virus encoded Bcl-2 homolog ORFV125 in complex with Puma BH3 peptide
Descriptor: 1,2-ETHANEDIOL, Activator of apoptosis harakiri, Apoptosis inhibitor, ...
Authors:Suraweera, C.D, Hinds, M.G, Kvansakul, M.
Deposit date:2021-06-30
Release date:2022-07-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.99374259 Å)
Cite:Structural Investigation of Orf Virus Bcl-2 Homolog ORFV125 Interactions with BH3-Motifs from BH3-Only Proteins Puma and Hrk.
Viruses, 13, 2021
7P0S
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ORF virus encoded Bcl-2 homolog ORFV125 in complex with Puma BH3 peptide
Descriptor: Apoptosis inhibitor, Bcl-2-binding component 3, isoforms 1/2
Authors:Suraweera, C.D, Hinds, M.G, Kvansakul, M.
Deposit date:2021-06-30
Release date:2022-07-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.50315881 Å)
Cite:Structural Investigation of Orf Virus Bcl-2 Homolog ORFV125 Interactions with BH3-Motifs from BH3-Only Proteins Puma and Hrk.
Viruses, 13, 2021
7P33
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Epstein-Barr virus encoded Bcl-2 homolog BHRF-1 in complex with Bid BH3 peptide
Descriptor: 1,2-ETHANEDIOL, Apoptosis regulator BHRF1, BH3-interacting domain death agonist p15, ...
Authors:Suraweera, C.D, Hinds, M.G, Kvansakul, M.
Deposit date:2021-07-07
Release date:2022-07-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.78542733 Å)
Cite:Crystal Structures of Epstein-Barr Virus Bcl-2 Homolog BHRF1 Bound to Bid and Puma BH3 Motif Peptides.
Viruses, 14, 2022
7P9W
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Epstein-Barr virus encoded apoptosis regulator BHRF1 in complex with Puma BH3
Descriptor: 1,2-ETHANEDIOL, 1,3-PROPANDIOL, AMMONIUM ION, ...
Authors:Suraweera, C.D, Hinds, M.G, Kvansakul, M.
Deposit date:2021-07-28
Release date:2022-08-10
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.00010061 Å)
Cite:Crystal Structures of Epstein-Barr Virus Bcl-2 Homolog BHRF1 Bound to Bid and Puma BH3 Motif Peptides.
Viruses, 14, 2022
6TQQ
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Structural insight into tanapoxvirus mediated inhibition of apoptosis
Descriptor: 16L protein, Bcl-2-like protein 11, SODIUM ION
Authors:Suraweera, C.D, Hinds, M.G, Kvansakul, M.
Deposit date:2019-12-17
Release date:2020-06-03
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (3.0017972 Å)
Cite:Structural insight into tanapoxvirus-mediated inhibition of apoptosis.
Febs J., 287, 2020
6TQP
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Structural insight into tanapoxvirus mediated inhibition of apoptosis
Descriptor: 16L protein, Bcl-2-binding component 3, isoforms 1/2, ...
Authors:Suraweera, C.D, Hinds, M.G, Kvansakul, M.
Deposit date:2019-12-17
Release date:2020-06-03
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.84940946 Å)
Cite:Structural insight into tanapoxvirus-mediated inhibition of apoptosis.
Febs J., 287, 2020
6TRR
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Structural insight into tanapoxvirus mediated inhibition of apoptosis
Descriptor: 16L protein, Apoptosis regulator BAX, SODIUM ION
Authors:Suraweera, C.D, Hinds, M.G, Kvansakul, M.
Deposit date:2019-12-19
Release date:2020-06-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.12007356 Å)
Cite:Structural insight into tanapoxvirus-mediated inhibition of apoptosis.
Febs J., 287, 2020
2JM6
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Solution structure of MCL-1 complexed with NOXAB
Descriptor: Myeloid cell leukemia-1 protein Mcl-1 homolog, Noxa
Authors:Czabotar, P.E, Lee, E.F, van Delft, M.F, Day, C.L, Smith, B.J, Huang, D.C.S, Fairlie, W.D, Hinds, M.G, Colman, P.M.
Deposit date:2006-10-17
Release date:2007-03-20
Last modified:2023-12-20
Method:SOLUTION NMR
Cite:Structural insights into the degradation of Mcl-1 induced by BH3 domains
Proc.Natl.Acad.Sci.Usa, 104, 2007
6WH0
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Crystal structure of HyBcl-2-4 with HyBax BH3
Descriptor: Apoptosis regulator BAX, Maltodextrin-binding protein,Bcl-2-like 4, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Kvansakul, M, Hinds, M.G, Banjara, S.
Deposit date:2020-04-07
Release date:2021-03-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:The structural basis of Bcl-2 mediated cell death regulation in hydra.
Biochem.J., 477, 2020
6WGZ
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Crystal structure of HyBcl-2-4 with HyBak1 BH3
Descriptor: ACETATE ION, Bak, Bcl-2-like 4, ...
Authors:Kvansakul, M, Hinds, M.G, Banjara, S.
Deposit date:2020-04-07
Release date:2021-04-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of HyBcl-2-4 with HyBak1 BH3 and HyBax BH3
To Be Published
6XY6
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Structural insight into sheep-pox virus mediated inhibition of apoptosis
Descriptor: Apoptosis regulator BAX, anti-apoptotic membrane protein
Authors:Suraweera, C.D, Hinds, M.G, Kvansakul, M.
Deposit date:2020-01-29
Release date:2020-07-29
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.91414642 Å)
Cite:Crystal structures of the sheeppox virus encoded inhibitor of apoptosis SPPV14 bound to the proapoptotic BH3 peptides Hrk and Bax.
Febs Lett., 594, 2020
6XY4
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Structural insight into sheep-pox virus mediated inhibition of apoptosis
Descriptor: Activator of apoptosis harakiri, anti-apoptotic membrane protein
Authors:Suraweera, C.D, Hinds, M.G, Kvansakul, M.
Deposit date:2020-01-29
Release date:2020-07-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.04623151 Å)
Cite:Crystal structures of the sheeppox virus encoded inhibitor of apoptosis SPPV14 bound to the proapoptotic BH3 peptides Hrk and Bax.
Febs Lett., 594, 2020

 

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