6XY6

Structural insight into sheep-pox virus mediated inhibition of apoptosis

Summary for 6XY6

• Entry DOI: 10.2210/pdb6xy6/pdb
• Descriptor: anti-apoptotic membrane protein, Apoptosis regulator BAX, ... (4 entities in total)
• Functional Keywords: pox virus, apoptosis, bcl-2
• Biological source: Sheeppox virus (strain Turkey/TU-V02127); More
• Total number of polymer chains: 16
• Total formula weight: 162559.90

Authors

Suraweera, C.D.,Hinds, M.G.,Kvansakul, M. (deposition date: 2020-01-29, release date: 2020-07-29)

• Primary citation: Suraweera, C.D.,Burton, D.R.,Hinds, M.G.,Kvansakul, M.; Crystal structures of the sheeppox virus encoded inhibitor of apoptosis SPPV14 bound to the proapoptotic BH3 peptides Hrk and Bax.; Febs Lett., 594:2016-2026, 2020; PubMed: 32390192; DOI: 10.1002/1873-3468.13807

Experimental method

X-RAY DIFFRACTION (2.91414639113 Å)