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PDB: 31 件

4ZVR
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Caspase-7 Variant 4 (V4) with reprogrammed substrate specificity due to Y230V/W232Y/S234V/Q276D substitutions bound to DEVD inhibitor.
分子名称: Caspase-7, Peptide ACE-ASP-GLU-VAL-ASJ
著者Hill, M.E, MacPherson, D.J, Hardy, J.A.
登録日2015-05-18
公開日2016-04-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Reprogramming Caspase-7 Specificity by Regio-Specific Mutations and Selection Provides Alternate Solutions for Substrate Recognition.
Acs Chem.Biol., 11, 2016
4ZVQ
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Caspase-7 Variant 2 (V2) with reprogrammed substrate specificity due to Y230V/W232M/Q276C substitutions bound to VEID inhibitor.
分子名称: Caspase-7, Peptide ACE-VAL-GLU-ILE-ASA
著者Hill, M.E, MacPherson, D.J, Hardy, J.A.
登録日2015-05-18
公開日2016-04-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Reprogramming Caspase-7 Specificity by Regio-Specific Mutations and Selection Provides Alternate Solutions for Substrate Recognition.
Acs Chem.Biol., 11, 2016
4ZVP
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Caspase-7 Variant 2 (V2) with reprogrammed substrate specificity due to Y230V/W232M/Q276C substitutions bound to DEVD inhibitor.
分子名称: Caspase-7, Peptide ACE-ASP-GLU-VAL-ASA
著者Hill, M.E, MacPherson, D.J, Hardy, J.A.
登録日2015-05-18
公開日2016-04-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Reprogramming Caspase-7 Specificity by Regio-Specific Mutations and Selection Provides Alternate Solutions for Substrate Recognition.
Acs Chem.Biol., 11, 2016
4ZVO
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Caspase-7 Variant 4 (V4) with reprogrammed substrate specificity due to Y230V/W232Y/S234V/Q276D substitutions bound to VEID inhibitor.
分子名称: Caspase-7, Peptide ACE-VAL-GLU-ILE-ASJ
著者Hill, M.E, MacPherson, D.J, Hardy, J.A.
登録日2015-05-18
公開日2016-04-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Reprogramming Caspase-7 Specificity by Regio-Specific Mutations and Selection Provides Alternate Solutions for Substrate Recognition.
Acs Chem.Biol., 11, 2016
5JBM
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Crystal structgure of Cac1 C-terminus
分子名称: Chromatin assembly factor 1 subunit p90
著者Churchill, M.E.A, Liu, W, Zhou, Y.
登録日2016-04-13
公開日2016-10-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The Cac1 subunit of histone chaperone CAF-1 organizes CAF-1-H3/H4 architecture and tetramerizes histones.
Elife, 5, 2016
6CC0
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Crystal structure of QscR bound to C12-homoserine lactone
分子名称: LuxR family transcriptional regulator, N-[(3S)-2-oxooxolan-3-yl]dodecanamide
著者Churchill, M.E.A, Wysoczynski-Horita, C.L.
登録日2018-02-05
公開日2018-02-28
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mechanism of agonism and antagonism of the Pseudomonas aeruginosa quorum sensing regulator QscR with non-native ligands.
Mol. Microbiol., 108, 2018
6CBQ
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Crystal structure of QscR bound to agonist S3
分子名称: (2S)-2-hexyl-N-[(3S)-2-oxooxolan-3-yl]decanamide, LuxR family transcriptional regulator
著者Churchill, M.E.A, Wysoczynski-Horita, C.L.
登録日2018-02-05
公開日2018-02-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mechanism of agonism and antagonism of the Pseudomonas aeruginosa quorum sensing regulator QscR with non-native ligands.
Mol. Microbiol., 108, 2018
1FRG
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CRYSTAL STRUCTURE, SEQUENCE, AND EPITOPE MAPPING OF A PEPTIDE COMPLEX OF AN ANTI-INFLUENZA HA PEPTIDE ANTIBODY FAB 26(SLASH)9: FINE-TUNING ANTIBODY SPECIFICITY
分子名称: IGG2A 26/9 FAB (HEAVY CHAIN), IGG2A 26/9 FAB (LIGHT CHAIN), INFLUENZA HEMAGGLUTININ HA1 (STRAIN X47) (RESIDUES 101 - 108)
著者Churchill, M.E.A, Wilson, I.A.
登録日1994-01-17
公開日1994-05-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of a peptide complex of anti-influenza peptide antibody Fab 26/9. Comparison of two different antibodies bound to the same peptide antigen.
J.Mol.Biol., 241, 1994
3NM9
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HMGD(M13A)-DNA complex
分子名称: DNA 5'-D(*G*GP*CP*GP*AP*TP*AP*TP*CP*GP*C)-3', High mobility group protein D
著者Churchill, M.E.A, Klass, J, Zoetewey, D.L.
登録日2010-06-22
公開日2010-09-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural analysis of HMGD-DNA complexes reveals influence of intercalation on sequence selectivity and DNA bending.
J.Mol.Biol., 403, 2010
3SZT
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Quorum Sensing Control Repressor, QscR, Bound to N-3-oxo-dodecanoyl-L-Homoserine Lactone
分子名称: N-3-OXO-DODECANOYL-L-HOMOSERINE LACTONE, Quorum-sensing control repressor, SODIUM ION
著者Churchill, M.E.A, Lintz, M.J.
登録日2011-07-19
公開日2011-09-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal structure of QscR, a Pseudomonas aeruginosa quorum sensing signal receptor.
Proc.Natl.Acad.Sci.USA, 108, 2011
4ZVU
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Caspase-7 wild-type bound to the caspase-6 cognate tetrapeptide inhibitor Ac-VEID-cho
分子名称: Caspase-7, Tetrapeptide Inhibitor Ac-VEID-CHO
著者Hardy, J.A, MacPherson, D.J, Hill, M.E.
登録日2015-05-18
公開日2016-04-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献Reprogramming Caspase-7 Specificity by Regio-Specific Mutations and Selection Provides Alternate Solutions for Substrate Recognition.
Acs Chem.Biol., 11, 2016
4ZVT
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Caspase-7 Variant 1 (V1) with reprogrammed substrate specificity due to Y230A/W232M/S234N substitutions, bound to VEID inhibitor.
分子名称: Caspase-7, VEID inhibitor
著者Hardy, J.A, MacPherson, D.J, Hill, M.E.
登録日2015-05-18
公開日2016-04-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Reprogramming Caspase-7 Specificity by Regio-Specific Mutations and Selection Provides Alternate Solutions for Substrate Recognition.
Acs Chem.Biol., 11, 2016
4ZVS
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BU of 4zvs by Molmil
Caspase-7 Variant 1 (V1) with reprogrammed substrate specificity due to Y230A/W232M/S234N substitutions, bound to DEVD inhibitor.
分子名称: Caspase-7, DEVD inhibitor
著者MacPherson, D.J, Hill, M.E, Hardy, J.A.
登録日2015-05-18
公開日2016-04-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Reprogramming Caspase-7 Specificity by Regio-Specific Mutations and Selection Provides Alternate Solutions for Substrate Recognition.
Acs Chem.Biol., 11, 2016
1RO5
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BU of 1ro5 by Molmil
Crystal Structure of the AHL Synthase LasI
分子名称: Autoinducer synthesis protein lasI, SULFATE ION, ZINC ION
著者Gould, T.A, Schweizer, H.P, Churchill, M.E.
登録日2003-12-01
公開日2004-08-24
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the Pseudomonas aeruginosa acyl-homoserinelactone synthase LasI.
Mol.Microbiol., 53, 2004
4EO5
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Yeast Asf1 bound to H3/H4G94P mutant
分子名称: ACETATE ION, GLYCEROL, Histone H3.2, ...
著者Scorgie, J.K, Churchill, M.E.
登録日2012-04-13
公開日2012-06-13
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献The conformational flexibility of the C-terminus of histone H4 promotes histone octamer and nucleosome stability and yeast viability.
Epigenetics Chromatin, 5, 2012
2PY0
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BU of 2py0 by Molmil
Crystal structure of Cs1 pilin chimera
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Fimbrial protein
著者Kao, D.J, Churchill, M.E, Hodges, R.S.
登録日2007-05-14
公開日2007-11-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Animal Protection and Structural Studies of a Consensus Sequence Vaccine Targeting the Receptor Binding Domain of the Type IV Pilus of Pseudomonas aeruginosa.
J.Mol.Biol., 374, 2007
7SJ5
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BU of 7sj5 by Molmil
Bacteriophage lambda major capsid protein mutant - W308A
分子名称: Major capsid protein
著者Davis, C.R, Churchill, M.E.
登録日2021-10-15
公開日2022-08-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.695 Å)
主引用文献Characterization of a Primordial Major Capsid-Scaffolding Protein Complex in Icosahedral Virus Shell Assembly.
J.Mol.Biol., 434, 2022
3FGH
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BU of 3fgh by Molmil
Human mitochondrial transcription factor A box B
分子名称: CADMIUM ION, CHLORIDE ION, SODIUM ION, ...
著者Gangelhoff, T.A, Mungalachetty, P, Nix, J, Churchill, M.E.A.
登録日2008-12-06
公開日2009-04-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structural analysis and DNA binding of the HMG domains of the human mitochondrial transcription factor A
Nucleic Acids Res., 37, 2009
8DEI
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BU of 8dei by Molmil
Structure of the Cac1 KER domain
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Maltodextrin-binding protein,Chromatin assembly factor 1 subunit p90 fusion, ...
著者Rosas, R, Churchill, M.E.A.
登録日2022-06-20
公開日2023-07-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献A novel single alpha-helix DNA-binding domain in CAF-1 promotes gene silencing and DNA damage survival through tetrasome-length DNA selectivity and spacer function.
Elife, 12, 2023
1K4J
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BU of 1k4j by Molmil
Crystal Structure of the Acyl-homoserinelactone Synthase EsaI Complexed with Rhenate
分子名称: PERRHENATE, acyl-homoserinelactone synthase EsaI
著者Watson, W.T, Minogue, T.D, Val, D.L, Beck von Bodman, S, Churchill, M.E.A.
登録日2001-10-08
公開日2002-04-17
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis and specificity of acyl-homoserine lactone signal production in bacterial quorum sensing.
Mol.Cell, 9, 2002
1EG2
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CRYSTAL STRUCTURE OF RHODOBACTER SPHEROIDES (N6 ADENOSINE) METHYLTRANSFERASE (M.RSRI)
分子名称: 5'-DEOXY-5'-METHYLTHIOADENOSINE, MODIFICATION METHYLASE RSRI
著者Scavetta, R.D, Thomas, C.B, Walsh, M.A, Szegedi, S, Joachimiak, A, Gumport, R.I, Churchill, M.E.A, Midwest Center for Structural Genomics (MCSG)
登録日2000-02-11
公開日2000-10-18
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure of RsrI methyltransferase, a member of the N6-adenine beta class of DNA methyltransferases.
Nucleic Acids Res., 28, 2000
4QR9
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Crystal structure of two HMGB1 Box A domains cooperating to underwind and kink a DNA
分子名称: DNA (5'-D(*AP*TP*AP*TP*CP*GP*AP*TP*AP*T)-3'), High mobility group protein B1, MAGNESIUM ION
著者Sanchez-Giraldo, R, Acosta-Reyes, F.J, Malarkey, C.S, Saperas, N, Churchill, M.E.A, Campos, J.L.
登録日2014-06-30
公開日2015-07-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Two high-mobility group box domains act together to underwind and kink DNA.
Acta Crystallogr.,Sect.D, 71, 2015
2C7A
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BU of 2c7a by Molmil
STRUCTURE OF THE PROGESTERONE RECEPTOR-DNA COMPLEX
分子名称: 5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*AP*AP *CP*TP*GP*TP*TP*CP*TP*G)-3', 5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*GP*TP *TP*TP*GP*TP*TP*CP*TP*G)-3', PROGESTERONE RECEPTOR, ...
著者Roemer, S.C, Donham, D.C, Sherman, L, Pon, V.H, Edwards, D.P, Churchill, M.E.A.
登録日2005-11-19
公開日2006-08-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of the Progesterone Receptor-Deoxyribonucleic Acid Complex: Novel Interactions Required for Binding to Half-Site Response Elements.
Mol.Endocrinol., 20, 2006
1HMA
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THE SOLUTION STRUCTURE AND DYNAMICS OF THE DNA BINDING DOMAIN OF HMG-D FROM DROSOPHILA MELANOGASTER
分子名称: HMG-D
著者Jones, D.N.M, Searles, M.A, Shaw, G.L, Churchill, M.E.A, Ner, S.S, Keeler, J, Travers, A.A, Neuhaus, D.
登録日1994-05-12
公開日1994-07-31
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The solution structure and dynamics of the DNA-binding domain of HMG-D from Drosophila melanogaster.
Structure, 2, 1994
2HUE
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Structure of the H3-H4 chaperone Asf1 bound to histones H3 and H4
分子名称: Anti-silencing protein 1, GLYCEROL, Histone H3, ...
著者English, C.M, Churchill, M.E.A, Tyler, J.K.
登録日2006-07-26
公開日2006-11-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis for the histone chaperone activity of asf1.
Cell(Cambridge,Mass.), 127, 2006

 

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