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PDB: 127 件

8RZ2
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PfRH5 bound to monoclonal antibody R5.034
分子名称: R5.034 heavy chain, R5.034 light chain, Reticulocyte binding protein 5
著者Farrell, B, Higgins, M.K.
登録日2024-02-11
公開日2024-07-17
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献PfRH5 bound to monoclonal antibody R5.034
To Be Published
8Q5R
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BU of 8q5r by Molmil
HpARI bound to mouse IL-33
分子名称: 1,2-ETHANEDIOL, Alarmin release inhibitor, CHLORIDE ION, ...
著者Jamwal, A, Higgins, M.K.
登録日2023-08-09
公開日2024-05-08
最終更新日2024-07-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for IL-33 recognition and its antagonism by the helminth effector protein HpARI2.
Nat Commun, 15, 2024
4E6Z
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Tic22 from Plasmodium falciparum
分子名称: Apicoplast TIC22, putative, GLYCEROL
著者Glaser, S, Higgins, M.K.
登録日2012-03-16
公開日2012-10-10
最終更新日2012-12-05
実験手法X-RAY DIFFRACTION (2.1501 Å)
主引用文献Tic22 is an essential chaperone required for protein import into the apicoplast.
J.Biol.Chem., 287, 2012
5A6B
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GH20C, Beta-hexosaminidase from Streptococcus pneumoniae in complex with PUGNAc
分子名称: MAGNESIUM ION, N-ACETYL-BETA-D-GLUCOSAMINIDASE, O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE
著者Cid, M, Robb, C.S, Higgins, M.A, Boraston, A.B.
登録日2015-06-24
公開日2015-09-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献A Second beta-Hexosaminidase Encoded in the Streptococcus pneumoniae Genome Provides an Expanded Biochemical Ability to Degrade Host Glycans.
J. Biol. Chem., 290, 2015
6RCO
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BU of 6rco by Molmil
PfRH5-binding monoclonal antibody R5.004
分子名称: ACETATE ION, GLYCEROL, R5.004 heavy chain, ...
著者Alanine, D.G.W, Draper, S.J, Higgins, M.K.
登録日2019-04-11
公開日2019-06-26
最終更新日2019-08-21
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies.
Cell, 178, 2019
6R2S
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BU of 6r2s by Molmil
The structure of Plasmodium vivax Duffy binding protein (PvDBP) bound to human antibody DB9
分子名称: Antibody DB9 heavy chain, Antibody DB9 light chain, Duffy receptor
著者Barber, N.M, Higgins, M.K.
登録日2019-03-18
公開日2019-03-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.04 Å)
主引用文献Structural basis for inhibition of Plasmodium vivax invasion by a broadly neutralizing vaccine-induced human antibody.
Nat Microbiol, 4, 2019
5AC5
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BU of 5ac5 by Molmil
GH20C, Beta-hexosaminidase from Streptococcus pneumoniae in complex with GlcNAc
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
著者Cid, M, Robb, C.S, Higgins, M.A, Boraston, A.B.
登録日2015-08-11
公開日2015-09-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献A Second beta-Hexosaminidase Encoded in the Streptococcus pneumoniae Genome Provides an Expanded Biochemical Ability to Degrade Host Glycans.
J. Biol. Chem., 290, 2015
5AC4
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GH20C, Beta-hexosaminidase from Streptococcus pneumoniae in complex with GalNAc
分子名称: 2-acetamido-2-deoxy-beta-D-galactopyranose, N-ACETYL-BETA-D-GLUCOSAMINIDASE
著者Cid, M, Robb, C.S, Higgins, M.A, Boraston, A.B.
登録日2015-08-11
公開日2015-09-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献A Second beta-Hexosaminidase Encoded in the Streptococcus pneumoniae Genome Provides an Expanded Biochemical Ability to Degrade Host Glycans.
J. Biol. Chem., 290, 2015
5A69
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GH20C, Beta-hexosaminidase from Streptococcus pneumoniae in complex with Gal-PUGNAc
分子名称: N-ACETYL-BETA-D-GLUCOSAMINIDASE, [(Z)-[(3R,4R,5R,6R)-3-acetamido-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-2-ylidene]amino] N-phenylcarbamate
著者Cid, M, Robb, C.S, Higgins, M.A, Boraston, A.B.
登録日2015-06-24
公開日2015-09-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A Second beta-Hexosaminidase Encoded in the Streptococcus pneumoniae Genome Provides an Expanded Biochemical Ability to Degrade Host Glycans.
J. Biol. Chem., 290, 2015
5A6A
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GH20C, Beta-hexosaminidase from Streptococcus pneumoniae in complex with NGT
分子名称: 1,2-ETHANEDIOL, 3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL, N-ACETYL-BETA-D-GLUCOSAMINIDASE
著者Cid, M, Robb, C.S, Higgins, M.A, Boraston, A.B.
登録日2015-06-24
公開日2015-09-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献A Second beta-Hexosaminidase Encoded in the Streptococcus pneumoniae Genome Provides an Expanded Biochemical Ability to Degrade Host Glycans.
J. Biol. Chem., 290, 2015
5A6J
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BU of 5a6j by Molmil
GH20C, Beta-hexosaminidase from Streptococcus pneumoniae
分子名称: 1,2-ETHANEDIOL, N-ACETYL-BETA-D-GLUCOSAMINIDASE
著者Cid, M, Robb, C.S, Higgins, M.A, Boraston, A.B.
登録日2015-06-26
公開日2015-09-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献A Second beta-Hexosaminidase Encoded in the Streptococcus pneumoniae Genome Provides an Expanded Biochemical Ability to Degrade Host Glycans.
J. Biol. Chem., 290, 2015
5A6K
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BU of 5a6k by Molmil
GH20C, Beta-hexosaminidase from Streptococcus pneumoniae in complex with Gal-NGT
分子名称: (2S,3aR,5R,6R,7R,7aR)-5-(hydroxymethyl)-2-methyl-2,3a,5,6,7,7a-hexahydro-1H-pyrano[3,2-d][1,3]thiazole-6,7-diol, GH20C
著者Cid, M, Robb, C.S, Higgins, M.A, Boraston, A.B.
登録日2015-06-26
公開日2015-09-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A Second Beta-Hexosaminidase Encoded in the Streptococcus Pneumoniae Genome Provides an Expanded Biochemical Ability to Degrade Host Glycans
J.Biol.Chem., 290, 2015
2J44
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BU of 2j44 by Molmil
Alpha-glucan binding by a streptococcal virulence factor
分子名称: ALKALINE AMYLOPULLULANASE, ZINC ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ...
著者Lammerts van Bueren, A, Higgins, M, Wang, D, Burke, R.D, Boraston, A.B.
登録日2006-08-24
公開日2006-12-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Identification and Structural Basis of Binding to Host Lung Glycogen by Streptococcal Virulence Factors.
Nat.Struct.Mol.Biol., 14, 2007
2J43
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BU of 2j43 by Molmil
Alpha-glucan recognition by family 41 carbohydrate-binding modules from streptococcal virulence factors
分子名称: SPYDX
著者Lammerts van Bueren, A, Higgins, M, Wang, D, Burke, R.D, Boraston, A.B.
登録日2006-08-24
公開日2006-12-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Identification and Structural Basis of Binding to Host Lung Glycogen by Streptococcal Virulence Factors.
Nat.Struct.Mol.Biol., 14, 2007
6RCQ
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BU of 6rcq by Molmil
PfRH5-binding monoclonal antibody R5.011
分子名称: ACETATE ION, CACODYLATE ION, R5.011 heavy chain, ...
著者Alanine, D.W.G, Draper, S.J, Higgins, M.K.
登録日2019-04-11
公開日2019-06-26
最終更新日2019-07-10
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies.
Cell, 178, 2019
6RCS
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BU of 6rcs by Molmil
PfRH5-binding monoclonal antibody R5.016
分子名称: ACETATE ION, R5.016 heavy chain, R5.016 light chain, ...
著者Alanine, D.W.G, Jamwal, A, Draper, S.J, Higgins, M.K.
登録日2019-04-11
公開日2019-06-26
最終更新日2019-08-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies.
Cell, 178, 2019
6RCV
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BU of 6rcv by Molmil
PfRH5 bound to monoclonal antibodies R5.011 and R5.016
分子名称: R5.011 heavy chain, R5.011 light chain, R5.016 heavy chain, ...
著者Alanine, D.W.G, Draper, S.J, Higgins, M.K.
登録日2019-04-11
公開日2019-06-26
最終更新日2019-07-10
実験手法X-RAY DIFFRACTION (3.582 Å)
主引用文献Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies.
Cell, 178, 2019
6RCU
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BU of 6rcu by Molmil
PfRH5 bound to monoclonal antibodies R5.004 and R5.016
分子名称: R5.004 heavy chain, R5.004 light chain, R5.016 heavy chain, ...
著者Alanine, D.W.G, Draper, S.J, Higgins, M.K.
登録日2019-04-11
公開日2019-06-26
最終更新日2019-08-21
実験手法X-RAY DIFFRACTION (4.005 Å)
主引用文献Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies.
Cell, 178, 2019
6SNY
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BU of 6sny by Molmil
Synthetic mimic of an EPCR-binding PfEMP1 bound to EPCR
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Endothelial protein C receptor, ...
著者Barber, N.M, Higgins, M.K.
登録日2019-08-27
公開日2019-09-04
最終更新日2021-01-20
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献Structure-Guided Design of a Synthetic Mimic of an Endothelial Protein C Receptor-Binding PfEMP1 Protein.
Msphere, 6, 2021
6SOY
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BU of 6soy by Molmil
Trypanosoma brucei transferrin receptor in complex with human transferrin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ESAG6, subunit of heterodimeric transferrin receptor, ...
著者Trevor, C, Carrington, M, Higgins, M.K.
登録日2019-08-30
公開日2019-11-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structure of the trypanosome transferrin receptor reveals mechanisms of ligand recognition and immune evasion.
Nat Microbiol, 4, 2019
6SOZ
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Glycosylated Trypanosoma brucei transferrin receptor in complex with human transferrin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ESAG6, ...
著者Trevor, C, Carrington, M, Higgins, M.K.
登録日2019-08-30
公開日2019-11-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.42 Å)
主引用文献Structure of the trypanosome transferrin receptor reveals mechanisms of ligand recognition and immune evasion.
Nat Microbiol, 4, 2019
6S8T
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BU of 6s8t by Molmil
Structure of the ICAM-1-binding PfEMP1 IT4var13 DBLbeta domain
分子名称: Erythrocyte membrane protein 1
著者Lennartz, F, Higgins, M.K.
登録日2019-07-10
公開日2019-09-25
最終更新日2019-10-09
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structural insights into diverse modes of ICAM-1 binding byPlasmodium falciparum-infected erythrocytes.
Proc.Natl.Acad.Sci.USA, 116, 2019
6S8U
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BU of 6s8u by Molmil
Structure of the PfEMP1 IT4var13 DBLbeta domain bound to ICAM-1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Erythrocyte membrane protein 1, ...
著者Lennartz, F, Higgins, M.K.
登録日2019-07-10
公開日2019-09-25
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.67 Å)
主引用文献Structural insights into diverse modes of ICAM-1 binding byPlasmodium falciparum-infected erythrocytes.
Proc.Natl.Acad.Sci.USA, 116, 2019
2YA1
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Product complex of a multi-modular glycogen-degrading pneumococcal virulence factor SpuA
分子名称: PUTATIVE ALKALINE AMYLOPULLULANASE, SODIUM ION, SULFATE ION, ...
著者Lammerts van Bueren, A, Ficko-Blean, E, Pluvinage, B, Hehemann, J.H, Higgins, M.A, Deng, L, Ogunniyi, A.D, Stroeher, U.H, Warry, N.E, Burke, R.D, Czjzek, M, Paton, J.C, Vocadlo, D.J, Boraston, A.B.
登録日2011-02-17
公開日2011-04-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The Conformation and Function of a Multimodular Glycogen-Degrading Pneumococcal Virulence Factor.
Structure, 19, 2011
2YA2
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Catalytic Module of the Multi-modular glycogen-degrading pneumococcal virulence factor SpuA in complex with an inhibitor.
分子名称: 1-DEOXYNOJIRIMYCIN, CALCIUM ION, PUTATIVE ALKALINE AMYLOPULLULANASE, ...
著者Lammerts van Bueren, A, Ficko-Blean, E, Pluvinage, B, Hehemann, J.H, Higgins, M.A, Deng, L, Ogunniyi, A.D, Stroeher, U.H, Warry, N.E, Burke, R.D, Czjzek, M, Paton, J.C, Vocadlo, D.J, Boraston, A.B.
登録日2011-02-17
公開日2011-04-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献The Conformation and Function of a Multimodular Glycogen-Degrading Pneumococcal Virulence Factor.
Structure, 19, 2011

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件を2024-07-24に公開中

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