5OCP
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6QP3
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![BU of 6qp3 by Molmil](/molmil-images/mine/6qp3) | Crystal structure of the PLP-bound C-S lyase from Bacillus subtilis (strain 168) | Descriptor: | ACETATE ION, Cystathionine beta-lyase PatB, PYRIDOXAL-5'-PHOSPHATE | Authors: | Herman, R, Rudden, M, Wilkinson, A.J, Hanai, S, Thomas, G.H. | Deposit date: | 2019-02-13 | Release date: | 2020-03-04 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The molecular basis of thioalcohol production in human body odour. Sci Rep, 10, 2020
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6QP1
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![BU of 6qp1 by Molmil](/molmil-images/mine/6qp1) | Crystal structure of the PLP-bound C-S lyase in the external aldimine form from Staphylococcus hominis complexed with an inhibitor, L-cycloserine. | Descriptor: | Aminotransferase, [5-hydroxy-6-methyl-4-({[(4E)-3-oxo-1,2-oxazolidin-4-ylidene]amino}methyl)pyridin-3-yl]methyl dihydrogen phosphate | Authors: | Herman, R, Rudden, M, Wilkinson, A.J, Hanai, S, Thomas, G.H. | Deposit date: | 2019-02-13 | Release date: | 2020-03-04 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | The molecular basis of thioalcohol production in human body odour. Sci Rep, 10, 2020
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6QP2
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![BU of 6qp2 by Molmil](/molmil-images/mine/6qp2) | Crystal structure of the PLP-bound C-S lyase from Staphylococcus hominis | Descriptor: | Aminotransferase, PYRIDOXAL-5'-PHOSPHATE, Polyhistidine tag | Authors: | Herman, R, Rudden, M, Wilkinson, A.J, Hanai, S, Thomas, G.H. | Deposit date: | 2019-02-13 | Release date: | 2020-03-04 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The molecular basis of thioalcohol production in human body odour. Sci Rep, 10, 2020
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8A0D
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![BU of 8a0d by Molmil](/molmil-images/mine/8a0d) | Crystal structure of the major guinea pig allergen Cav p 1.0101 part of the lipocalin family | Descriptor: | Allergen lipocalin Cav p 1 isoform 1 | Authors: | Herman, R, Charlier, P, Janssen-Weets, B, Hilger, C, Swiontek, K. | Deposit date: | 2022-05-27 | Release date: | 2022-08-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.685 Å) | Cite: | Mammalian derived lipocalin and secretoglobin respiratory allergens strongly bind ligands with potentially immune modulating properties. Front Allergy, 3, 2022
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7PJJ
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![BU of 7pjj by Molmil](/molmil-images/mine/7pjj) | Structure of the Family-3 Glycosyl Hydrolase BcpE2 from Streptomyces scabies | Descriptor: | Beta-glucosidase, GLYCEROL | Authors: | Jadot, C, Herman, R, Deflandre, B, Rigali, S, Kerff, F. | Deposit date: | 2021-08-24 | Release date: | 2022-07-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.086 Å) | Cite: | Structure and Function of BcpE2, the Most Promiscuous GH3-Family Glucose Scavenging Beta-Glucosidase. Mbio, 13, 2022
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1W79
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![BU of 1w79 by Molmil](/molmil-images/mine/1w79) | Crystal structure of the DD-transpeptidase-carboxypeptidase from Actinomadura R39 | Descriptor: | D-alanyl-D-alanine carboxypeptidase, MAGNESIUM ION, SULFATE ION | Authors: | Sauvage, E, Herman, R, Petrella, S, Duez, C, Frere, J.M, Charlier, P. | Deposit date: | 2004-08-31 | Release date: | 2005-06-28 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the Actinomadura R39 DD-peptidase reveals new domains in penicillin-binding proteins. J. Biol. Chem., 280, 2005
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1W8Q
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![BU of 1w8q by Molmil](/molmil-images/mine/1w8q) | Crystal Structure of the DD-Transpeptidase-carboxypeptidase from Actinomadura R39 | Descriptor: | COBALT (II) ION, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, SULFATE ION | Authors: | Sauvage, E, Herman, R, Petrella, S, Duez, C, Frere, J.M, Charlier, P. | Deposit date: | 2004-09-24 | Release date: | 2005-06-28 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Crystal Structure of the Actinomadura R39 Dd-Peptidase Reveals New Domains in Penicillin-Binding Proteins. J.Biol.Chem., 280, 2005
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1W8Y
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![BU of 1w8y by Molmil](/molmil-images/mine/1w8y) | Crystal structure of the nitrocefin acyl-DD-peptidase from Actinomadura R39. | Descriptor: | (2R)-2-{(1R)-2-OXO-1-[(2-THIENYLACETYL)AMINO]ETHYL}-5,6-DIHYDRO-2H-1,3-THIAZINE-4-CARBOXYLIC ACID, D-alanyl-D-alanine carboxypeptidase, MAGNESIUM ION, ... | Authors: | Sauvage, E, Herman, R, Petrella, S, Duez, C, Frere, J.M, Charlier, P. | Deposit date: | 2004-10-01 | Release date: | 2005-06-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure of the Actinomadura R39 Dd- Peptidase Reveals New Domains in Penicillin- Binding Proteins. J.Biol.Chem., 280, 2005
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1W7F
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6SE1
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![BU of 6se1 by Molmil](/molmil-images/mine/6se1) | Structure of Salmonella ser. Paratyphi A lipopolysaccharide acetyltransferase periplasmic domain | Descriptor: | DI(HYDROXYETHYL)ETHER, Putative lipopolysaccharide modification acyltransferase, SULFATE ION | Authors: | Tindall, S.N, Pearson, C, Herman, R, Jenkins, H.T, Thomas, G.H, Potts, J.R, Van der Woude, M. | Deposit date: | 2019-07-29 | Release date: | 2020-08-26 | Last modified: | 2020-09-16 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | Acetylation of Surface Carbohydrates in Bacterial Pathogens Requires Coordinated Action of a Two-Domain Membrane-Bound Acyltransferase. Mbio, 11, 2020
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5HJL
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![BU of 5hjl by Molmil](/molmil-images/mine/5hjl) | Crystal structure of class I tagatose 1,6-bisphosphate aldolase LacD from Streptococcus porcinus | Descriptor: | SULFATE ION, Tagatose 1,6-diphosphate aldolase | Authors: | Freichels, R, Kerff, F, Herman, R, Charlier, P, Galleni, M. | Deposit date: | 2016-01-13 | Release date: | 2016-12-07 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure and Characterization of a new class I Tagatose-1,6-bipshosphate aldolase from Streptococcus porcinus : switch in specificity directed by an Arginine To Be Published
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4D2O
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![BU of 4d2o by Molmil](/molmil-images/mine/4d2o) | Crystal structure of the class A extended-spectrum beta-lactamase PER- 2 | Descriptor: | PER-2 BETA-LACTAMASE | Authors: | Power, P, Herman, R, Ruggiero, M, Kerff, F, Galleni, M, Gutkind, G, Charlier, P, Sauvage, E. | Deposit date: | 2014-05-12 | Release date: | 2014-05-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of the Extended-Spectrum Beta-Lactamase Per- 2 and Insights Into the Role of Specific Residues in the Interaction with Beta-Lactams and Beta-Lactamase Inhibitors. Antimicrob.Agents Chemother., 58, 2014
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3TVL
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![BU of 3tvl by Molmil](/molmil-images/mine/3tvl) | Complex between the human thiamine triphosphatase and triphosphate | Descriptor: | 1,2-ETHANEDIOL, TRIPHOSPHATE, Thiamine-triphosphatase | Authors: | Delvaux, D, Herman, R, Sauvage, E, Wins, P, Bettendorff, L, Charlier, P, Kerff, F. | Deposit date: | 2011-09-20 | Release date: | 2012-10-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural determinants of specificity and catalytic mechanism in mammalian 25-kDa thiamine triphosphatase. Biochim.Biophys.Acta, 1830, 2013
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4M3J
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![BU of 4m3j by Molmil](/molmil-images/mine/4m3j) | Structure of a single-domain camelid antibody fragment cAb-H7S specific of the BlaP beta-lactamase from Bacillus licheniformis | Descriptor: | Camelid heavy-chain antibody variable fragment cAb-H7S, SULFATE ION | Authors: | Pain, C, Kerff, F, Herman, R, Sauvage, E, Preumont, S, Charlier, P, Dumoulin, M. | Deposit date: | 2013-08-06 | Release date: | 2014-08-06 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Probing the mechanism of aggregation of polyQ model proteins with camelid heavy-chain antibody fragments To be Published
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4N1H
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![BU of 4n1h by Molmil](/molmil-images/mine/4n1h) | Structure of a single-domain camelid antibody fragment cAb-F11N in complex with the BlaP beta-lactamase from Bacillus licheniformis | Descriptor: | Beta-lactamase, Camelid heavy-chain antibody variable fragment cAb-F11N | Authors: | Pain, C, Kerff, F, Herman, R, Sauvage, E, Preumont, S, Charlier, P, Dumoulin, M. | Deposit date: | 2013-10-04 | Release date: | 2014-10-08 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Probing the mechanism of aggregation of polyQ model proteins with camelid heavy-chain antibody fragments To be Published
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4M3K
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![BU of 4m3k by Molmil](/molmil-images/mine/4m3k) | Structure of a single domain camelid antibody fragment cAb-H7S in complex with the BlaP beta-lactamase from Bacillus licheniformis | Descriptor: | Beta-lactamase, CHLORIDE ION, Camelid heavy-chain antibody variable fragment cAb-H7S | Authors: | Pain, C, Kerff, F, Herman, R, Sauvage, E, Preumont, S, Charlier, P, Dumoulin, M. | Deposit date: | 2013-08-06 | Release date: | 2014-08-06 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Probing the mechanism of aggregation of polyQ model proteins with camelid heavy-chain antibody fragments To be Published
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1W7G
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![BU of 1w7g by Molmil](/molmil-images/mine/1w7g) | Alpha-thrombin complex with sulfated hirudin (residues 54-65) and L- Arginine template inhibitor CS107 | Descriptor: | HIRUDIN I, N-{(1S)-1-{[4-(3-AMINOPROPYL)PIPERAZIN-1-YL]CARBONYL}-4-[(DIAMINOMETHYLENE)AMINO]BUTYL}-3-(TRIFLUOROMETHYL)BENZENESULFONAMIDE, THROMBIN | Authors: | Remiche, J, Sauvage, E, Herman, R, Charlier, P. | Deposit date: | 2004-09-02 | Release date: | 2006-05-24 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Design, Synthesis and Evaluation of Graftable Thrombin Inhibitors for the Preparation of Blood-Compatible Polymer Materials. Org.Biomol.Chem., 3, 2005
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5AEB
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![BU of 5aeb by Molmil](/molmil-images/mine/5aeb) | Crystal structure of the class B3 di-zinc metallo-beta-lactamase LRA- 12 from an Alaskan soil metagenome. | Descriptor: | COBALT (II) ION, LRA-12, SULFATE ION, ... | Authors: | Power, P, Herman, R, Kerff, F, Bouillenne, F, Rodriguez, M.M, Galleni, M, Handelsman, J, Gutkind, G, Charlier, P, Sauvage, E. | Deposit date: | 2015-08-27 | Release date: | 2015-09-16 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure and kinetic analysis of the class B3 di-zinc metallo-beta-lactamase LRA-12 from an Alaskan soil metagenome. PLoS ONE, 12, 2017
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7AP7
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![BU of 7ap7 by Molmil](/molmil-images/mine/7ap7) | Structure of the W64R amyloidogenic variant of human lysozyme | Descriptor: | Lysozyme C, SULFATE ION | Authors: | Vettore, N, Herman, R, Kerff, F, Charlier, P, Sauvage, E, Brans, A, Morray, J, Dobson, C, Kumita, J, Dumoulin, M. | Deposit date: | 2020-10-16 | Release date: | 2021-08-25 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Characterisation of the structural, dynamic and aggregation properties of the W64R amyloidogenic variant of human lysozyme. Biophys.Chem., 271, 2021
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1W5D
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![BU of 1w5d by Molmil](/molmil-images/mine/1w5d) | Crystal structure of PBP4a from Bacillus subtilis | Descriptor: | CALCIUM ION, PENICILLIN-BINDING PROTEIN | Authors: | Sauvage, E, Herman, R, Petrella, S, Duez, C, Frere, J.M, Charlier, P. | Deposit date: | 2004-08-06 | Release date: | 2005-12-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure of the Bacillus Subtilis Penicillin-Binding Protein 4A, and its Complex with a Peptidoglycan Mimetic Peptide. J.Mol.Biol., 371, 2007
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3ZVT
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![BU of 3zvt by Molmil](/molmil-images/mine/3zvt) | Unexpected tricovalent binding mode of boronic acids within the active site of a penicillin binding protein | Descriptor: | 2,6 DIMETHOXYBENZAMIDOBORONIC ACID, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, MAGNESIUM ION, ... | Authors: | Sauvage, E, Zervosen, A, Herman, R, Kerff, F, Rocaboy, M, Charlier, P. | Deposit date: | 2011-07-27 | Release date: | 2012-02-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Unexpected Tricovalent Binding Mode of Boronic Acids within the Active Site of a Penicillin- Binding Protein. J.Am.Chem.Soc., 133, 2011
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3ZVW
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![BU of 3zvw by Molmil](/molmil-images/mine/3zvw) | Unexpected tricovalent binding mode of boronic acids within the active site of a penicillin binding protein | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3,3-DIMETHYLBUTAN-1-OL, ACETONE, ... | Authors: | Sauvage, E, Zervosen, A, Herman, R, Kerff, F, Rocaboy, M, Charlier, P. | Deposit date: | 2011-07-28 | Release date: | 2012-02-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Unexpected Tricovalent Binding Mode of Boronic Acids within the Active Site of a Penicillin- Binding Protein. J.Am.Chem.Soc., 133, 2011
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8BM3
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![BU of 8bm3 by Molmil](/molmil-images/mine/8bm3) | H207A mutant of E. coli PgpB, a PAP2 type phosphatidyl glycerol phosphate and C55-PP phosphatase, in complex with farnesyl pyrophosphate | Descriptor: | FARNESYL DIPHOSPHATE, Phosphatidylglycerophosphatase B | Authors: | Delbrassine, F, El Ghachi, M, Lambion, A, Herman, R, Kerff, F. | Deposit date: | 2022-11-10 | Release date: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | H207A mutant of E. coli PgpB, a PAP2 type phosphatidyl glycerol phosphate and C55-PP phosphatase, in complex with farnesyl pyrophosphate To Be Published
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6YCG
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![BU of 6ycg by Molmil](/molmil-images/mine/6ycg) | Structure the bromelain protease from Ananas comosus in complex with the TLCK inhibitor | Descriptor: | CITRIC ACID, FBSB, ISOPROPYL ALCOHOL, ... | Authors: | Azarkan, M, Charlier, P, Herman, R, Delbrassine, F, Sauvage, E, M Rabet, N, Calvo Esposito, R, Kerff, F. | Deposit date: | 2020-03-18 | Release date: | 2020-11-25 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structures of the free and inhibitors-bound forms of bromelain and ananain from Ananas comosus stem and in vitro study of their cytotoxicity. Sci Rep, 10, 2020
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