8P8H
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![BU of 8p8h by Molmil](/molmil-images/mine/8p8h) | Crystal structure of HHD2 domain of hRTEL1 | Descriptor: | Regulator of telomere elongation helicase 1 | Authors: | Hegde, R.P, Kanade, M, Cortone, G, Graewert, M, Longo, A, Gonzalez, A, Chaves-Arquero, B, Blanco, F.J, Napolitano, L.M.R, Onesti, S. | Deposit date: | 2023-06-01 | Release date: | 2024-06-12 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of HHD2 domain of hRTEL1 To Be Published
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1BY9
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![BU of 1by9 by Molmil](/molmil-images/mine/1by9) | |
6Y4L
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![BU of 6y4l by Molmil](/molmil-images/mine/6y4l) | |
6Z3W
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![BU of 6z3w by Molmil](/molmil-images/mine/6z3w) | Human ER membrane protein complex | Descriptor: | ER membrane protein complex subunit 1,ER membrane protein complex subunit 1,ER membrane protein complex subunit 1,ER membrane protein complex subunit 1, ER membrane protein complex subunit 10, ER membrane protein complex subunit 2, ... | Authors: | Hegde, R.S, O'Donnell, J.P. | Deposit date: | 2020-05-22 | Release date: | 2020-07-15 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (6.4 Å) | Cite: | The architecture of EMC reveals a path for membrane protein insertion. Elife, 9, 2020
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4HN8
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![BU of 4hn8 by Molmil](/molmil-images/mine/4hn8) | Crystal structure of a putative D-glucarate dehydratase from Pseudomonas mendocina ymp | Descriptor: | D-glucarate dehydratase, GLYCEROL | Authors: | Hegde, R.P, Toro, R, Burley, S.K, Almo, S.C, Ramagopal, U.A, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2012-10-19 | Release date: | 2012-11-07 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of a putative D-glucarate dehydratase from Pseudomonas mendocina ymp To be published
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4JHM
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![BU of 4jhm by Molmil](/molmil-images/mine/4jhm) | Crystal structure of a putative mandelate racemase/muconate lactonizing enzyme from Pseudovibrio sp. | Descriptor: | Mandelate racemase / muconate lactonizing enzyme, C-terminal domain protein | Authors: | Hegde, R.P, Toro, R, Burley, S.K, Almo, S.C, Ramagopal, U.A, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2013-03-05 | Release date: | 2013-05-01 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of a putative mandelate racemase/muconate lactonizing enzyme from Pseudovibrio sp. To be published
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4HYR
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![BU of 4hyr by Molmil](/molmil-images/mine/4hyr) | Structure of putative Glucarate dehydratase from Acidaminococcus sp. D21 with unusual static disorder | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... | Authors: | Hegde, R.P, Toro, R, Burley, S.K, Almo, S.C, Ramagopal, U.A, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2012-11-14 | Release date: | 2013-02-13 | Last modified: | 2021-02-10 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Structure of putative Glucarate dehydratase from Acidaminococcus sp. D21 with unusual static disorder To be published
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2BOP
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![BU of 2bop by Molmil](/molmil-images/mine/2bop) | CRYSTAL STRUCTURE AT 1.7 ANGSTROMS OF THE BOVINE PAPILLOMAVIRUS-1 E2 DNA-BINDING DOMAIN BOUND TO ITS DNA TARGET | Descriptor: | DNA (5'-D(*CP*CP*GP*AP*CP*CP*GP*AP*CP*GP*TP*CP*GP*GP*TP*CP*G )-3'), PROTEIN (E2), YTTERBIUM (III) ION | Authors: | Hegde, R.S, Grossman, S.R, Laimins, L.A, Sigler, P.B. | Deposit date: | 1994-01-13 | Release date: | 1994-01-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure at 1.7 A of the bovine papillomavirus-1 E2 DNA-binding domain bound to its DNA target. Nature, 359, 1992
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3BY2
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![BU of 3by2 by Molmil](/molmil-images/mine/3by2) | Norwalk P polypeptide (228-523) | Descriptor: | 58 kd capsid protein | Authors: | Hegde, R, Bu, W. | Deposit date: | 2008-01-15 | Release date: | 2008-04-22 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for the receptor binding specificity of Norwalk virus. J.Virol., 82, 2008
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3BY1
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![BU of 3by1 by Molmil](/molmil-images/mine/3by1) | Unliganded Norvalk Virus P domain | Descriptor: | 58 kd capsid protein | Authors: | Hegde, R, Bu, W. | Deposit date: | 2008-01-15 | Release date: | 2008-04-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Structural basis for the receptor binding specificity of Norwalk virus. J.Virol., 82, 2008
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2F61
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![BU of 2f61 by Molmil](/molmil-images/mine/2f61) | Crystal structure of partially deglycosylated acid beta-glucosidase | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acid beta-glucosidase, ... | Authors: | Hegde, R.S, Grabowski, G. | Deposit date: | 2005-11-28 | Release date: | 2005-12-27 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Analyses of Variant Acid beta-Glucosidases: EFFECTS OF GAUCHER DISEASE MUTATIONS. J.Biol.Chem., 281, 2006
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3D26
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![BU of 3d26 by Molmil](/molmil-images/mine/3d26) | Norwalk P domain A-trisaccharide complex | Descriptor: | 58 kd capsid protein, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)]beta-D-galactopyranose | Authors: | Hegde, R, Bu, W. | Deposit date: | 2008-05-07 | Release date: | 2008-06-10 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for the receptor binding specificity of Norwalk virus. J.Virol., 82, 2008
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1JJH
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![BU of 1jjh by Molmil](/molmil-images/mine/1jjh) | |
5LZU
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![BU of 5lzu by Molmil](/molmil-images/mine/5lzu) | Structure of the mammalian ribosomal termination complex with accommodated eRF1 | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | Authors: | Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. | Deposit date: | 2016-10-02 | Release date: | 2016-11-30 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.75 Å) | Cite: | Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes. Cell, 167, 2016
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5LZZ
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![BU of 5lzz by Molmil](/molmil-images/mine/5lzz) | Structure of the mammalian rescue complex with Pelota and Hbs1l (combined) | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | Authors: | Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. | Deposit date: | 2016-10-02 | Release date: | 2016-11-30 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes. Cell, 167, 2016
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5LZY
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![BU of 5lzy by Molmil](/molmil-images/mine/5lzy) | Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a polyadenylated mRNA. | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | Authors: | Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. | Deposit date: | 2016-10-02 | Release date: | 2016-11-30 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.99 Å) | Cite: | Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes. Cell, 167, 2016
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8BPO
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![BU of 8bpo by Molmil](/molmil-images/mine/8bpo) | Structure of rabbit 80S ribosome translating beta-tubulin in complex with tetratricopeptide protein 5 (TTC5) and S-phase Cyclin A Associated Protein residing in the ER (SCAPER) | Descriptor: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Hopfler, M, Absmeier, E, Passmore, L.A, Hegde, R.S. | Deposit date: | 2022-11-17 | Release date: | 2023-07-05 | Last modified: | 2023-07-19 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Mechanism of ribosome-associated mRNA degradation during tubulin autoregulation. Mol.Cell, 83, 2023
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4MB6
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![BU of 4mb6 by Molmil](/molmil-images/mine/4mb6) | Crystal structure of adenine phosphoribosyltransferase from Yersinia pseudotuberculosis. | Descriptor: | Adenine phosphoribosyltransferase, SODIUM ION | Authors: | Pavithra, G.C, Kim, J, Hegde, R.P, Almo, S.C, Ramagopal, U.A, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2013-08-19 | Release date: | 2013-09-04 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Crystal structure of adenine phosphoribosyltransferase from Yersinia pseudotuberculosis To be published
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5KZK
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![BU of 5kzk by Molmil](/molmil-images/mine/5kzk) | Crystal Structure of rRNA methyltransferase from Sinorhizobium meliloti | Descriptor: | COBALT (II) ION, Probable RNA methyltransferase, TrmH family, ... | Authors: | Dey, D, Hegde, R.P, Almo, S.C, Ramakumar, S, Ramagopal, U.A, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2016-07-25 | Release date: | 2017-08-02 | Last modified: | 2019-11-20 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Crystal Structure of rRNA methyltransferase from Sinorhizobium meliloti To Be Published
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5L0Z
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![BU of 5l0z by Molmil](/molmil-images/mine/5l0z) | Crystal Structure of AdoMet bound rRNA methyltransferase from Sinorhizobium meliloti | Descriptor: | COBALT (II) ION, Probable RNA methyltransferase, TrmH family, ... | Authors: | Dey, D, Hegde, R.P, Almo, S.C, Ramakumar, S, Ramagopal, U.A. | Deposit date: | 2016-07-28 | Release date: | 2017-08-02 | Last modified: | 2019-11-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal Structure of AdoMet bound rRNA methyltransferase from Sinorhizobium meliloti To Be Published
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7QWR
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![BU of 7qwr by Molmil](/molmil-images/mine/7qwr) | Structure of the ribosome-nascent chain containing an ER signal sequence in complex with NAC | Descriptor: | 28S rRNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Jomaa, A, Gamerdinger, M, Hsieh, H, Wallisch, A, Chandrasekaran, V, Ulusoy, Z, Scaiola, A, Hegde, R, Shan, S, Ban, N, Deuerling, E. | Deposit date: | 2022-01-25 | Release date: | 2022-03-09 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting. Science, 375, 2022
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7QWS
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![BU of 7qws by Molmil](/molmil-images/mine/7qws) | Structure of ribosome translating beta-tubulin in complex with TTC5 and NAC | Descriptor: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Jomaa, A, Gamerdinger, M, Hsieh, H, Wallisch, A, Chandrasekaran, V, Ulusoy, Z, Scaiola, A, Hegde, R, Shan, S, Ban, N, Deuerling, E. | Deposit date: | 2022-01-25 | Release date: | 2022-03-09 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting. Science, 375, 2022
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7QWQ
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![BU of 7qwq by Molmil](/molmil-images/mine/7qwq) | Ternary complex of ribosome nascent chain with SRP and NAC | Descriptor: | 28S rRNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Jomaa, A, Gamerdinger, M, Hsieh, H, Wallisch, A, Chandrasekaran, V, Ulusoy, Z, Scaiola, A, Hegde, R, Shan, S, Ban, N, Deuerling, E. | Deposit date: | 2022-01-25 | Release date: | 2022-03-16 | Last modified: | 2022-03-30 | Method: | ELECTRON MICROSCOPY (2.83 Å) | Cite: | Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting. Science, 375, 2022
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7TM3
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![BU of 7tm3 by Molmil](/molmil-images/mine/7tm3) | Structure of the rabbit 80S ribosome stalled on a 2-TMD Rhodopsin intermediate in complex with the multipass translocon | Descriptor: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Kim, M.K, Lewis, A.J.O, Keenan, R.J, Hegde, R.S. | Deposit date: | 2022-01-19 | Release date: | 2022-10-19 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Mechanism of an intramembrane chaperone for multipass membrane proteins. Nature, 611, 2022
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7TUT
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![BU of 7tut by Molmil](/molmil-images/mine/7tut) | Structure of the rabbit 80S ribosome stalled on a 4-TMD Rhodopsin intermediate in complex with the multipass translocon | Descriptor: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Kim, M.K, Lewis, A.J.O, Keenan, R.J, Hegde, R.S. | Deposit date: | 2022-02-03 | Release date: | 2022-10-19 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.88 Å) | Cite: | Mechanism of an intramembrane chaperone for multipass membrane proteins. Nature, 611, 2022
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