4POL
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![BU of 4pol by Molmil](/molmil-images/mine/4pol) | Crystal structures of thioredoxin with mesna at 2.8A resolution | Descriptor: | 1-THIOETHANESULFONIC ACID, Thioredoxin | Authors: | Sridhar, V, Chie-Leon, B, Badger, J, Nienaber, V.L, Hausheer, F.H. | Deposit date: | 2014-02-26 | Release date: | 2014-10-29 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | BNP7787 Forms Novel Covalent
Adducts on Human Thioredoxin
and Modulates Thioredoxin
Activity J Pharmacol Clin Toxicol, 2, 2014
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4POK
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![BU of 4pok by Molmil](/molmil-images/mine/4pok) | Crystal structures of thioredoxin with mesna at 2.5A resolution | Descriptor: | 1-THIOETHANESULFONIC ACID, Thioredoxin | Authors: | Sridhar, V, Chie-Leon, B, Badger, J, Nienaber, V.L, Hausheer, F.H. | Deposit date: | 2014-02-25 | Release date: | 2014-10-29 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | BNP7787 Forms Novel Covalent
Adducts on Human Thioredoxin
and Modulates Thioredoxin
Activity J Pharmacol Clin Toxicol, 2, 2014
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4POM
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![BU of 4pom by Molmil](/molmil-images/mine/4pom) | Crystal structures of thioredoxin with mesna at 1.85A resolution | Descriptor: | 1-THIOETHANESULFONIC ACID, Thioredoxin | Authors: | Sridhar, V, Chie-Leon, B, Badger, J, Nienaber, V.L, Hausheer, F.H. | Deposit date: | 2014-02-26 | Release date: | 2014-10-29 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | BNP7787 Forms Novel Covalent
Adducts on Human Thioredoxin
and Modulates Thioredoxin
Activity J Pharmacol Clin Toxicol, 2, 2014
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4RQR
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![BU of 4rqr by Molmil](/molmil-images/mine/4rqr) | Crystal Structure of Human Glutaredoxin with MESNA | Descriptor: | 1-THIOETHANESULFONIC ACID, Glutaredoxin-1 | Authors: | Badger, J, Sridhar, V, Logan, C, Hausheer, F.H, Nienaber, V.L. | Deposit date: | 2014-11-04 | Release date: | 2015-04-01 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | Cysteine Specific Targeting of the Functionally Distinct Peroxiredoxin and Glutaredoxin Proteins by the Investigational Disulfide BNP7787. Molecules, 20, 2015
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4TT7
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![BU of 4tt7 by Molmil](/molmil-images/mine/4tt7) | Crystal structure of human ALK with a covalent modification | Descriptor: | 1,2-ETHANEDIOL, 1-THIOETHANESULFONIC ACID, ALK tyrosine kinase receptor | Authors: | Badger, J, Sridhar, V, Chie-Leon, B, Nienaber, V.L, Hausheer, F.H. | Deposit date: | 2014-06-19 | Release date: | 2015-02-11 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Novel covalent modification of human anaplastic lymphoma kinase (ALK) and potentiation of crizotinib-mediated inhibition of ALK activity by BNP7787. Onco Targets Ther, 8, 2015
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4RQX
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![BU of 4rqx by Molmil](/molmil-images/mine/4rqx) | Crystal structure of human peroxiredoxin 4(THIOREDOXIN PEROXIDASE) with MESNA | Descriptor: | 1-THIOETHANESULFONIC ACID, Peroxiredoxin-4 | Authors: | Badger, J, Sridhar, V, Logan, C, Hausheer, F.H, Nienaber, V.L. | Deposit date: | 2014-11-05 | Release date: | 2015-04-01 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.256 Å) | Cite: | Cysteine Specific Targeting of the Functionally Distinct Peroxiredoxin and Glutaredoxin Proteins by the Investigational Disulfide BNP7787. Molecules, 20, 2015
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