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4POK

Crystal structures of thioredoxin with mesna at 2.5A resolution

Summary for 4POK
Entry DOI10.2210/pdb4pok/pdb
Related4POL 4POM
DescriptorThioredoxin, 1-THIOETHANESULFONIC ACID (3 entities in total)
Functional Keywordsoxidoreductase
Biological sourceHomo sapiens (human)
Cellular locationNucleus: P10599
Total number of polymer chains4
Total formula weight48346.42
Authors
Sridhar, V.,Chie-Leon, B.,Badger, J.,Nienaber, V.L.,Hausheer, F.H. (deposition date: 2014-02-25, release date: 2014-10-29, Last modification date: 2024-11-27)
Primary citationParker, A.R.,Nienaber, V.L.,Petluru, P.N.,Sridhar, V.,Leverett, B.D.,Ayala, P.Y.,Zhao, M.,Chie-Leon, B.,Jair, K.,Kochat, H.,Badger, J.,Hausheer, F.H.
BNP7787 Forms Novel Covalent Adducts on Human Thioredoxin and Modulates Thioredoxin Activity
J Pharmacol Clin Toxicol, 2:1026-, 2014
Experimental method
X-RAY DIFFRACTION (2.52 Å)
Structure validation

229183

PDB entries from 2024-12-18

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