6T6V
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![BU of 6t6v by Molmil](/molmil-images/mine/6t6v) | Glu-494-Ala inactive monomer of a quinol dependent Nitric Oxide Reductase (qNOR) from Alcaligenes xylosoxidans | Descriptor: | CALCIUM ION, Nitric oxide reductase subunit B, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Gopalasingam, C.C, Johnson, R.M, Antonyuk, S.V, Muench, S.P, Hasnain, S.S. | Deposit date: | 2019-10-19 | Release date: | 2020-04-01 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | The active form of quinol-dependent nitric oxide reductase fromNeisseria meningitidisis a dimer. Iucrj, 7, 2020
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6TFD
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![BU of 6tfd by Molmil](/molmil-images/mine/6tfd) | Crystal structure of nitrite and NO bound three-domain copper-containing nitrite reductase from Hyphomicrobium denitrificans strain 1NES1 | Descriptor: | COPPER (II) ION, Copper-containing nitrite reductase, NITRIC OXIDE, ... | Authors: | Sasaki, D, Watanabe, T.F, Eady, R.R, Garratt, R.C, Antonyuk, S.V, Hasnain, S.S. | Deposit date: | 2019-11-13 | Release date: | 2020-06-10 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structures of substrate- and product-bound forms of a multi-domain copper nitrite reductase shed light on the role of domain tethering in protein complexes. Iucrj, 7, 2020
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6TFO
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![BU of 6tfo by Molmil](/molmil-images/mine/6tfo) | Crystal structure of as isolated three-domain copper-containing nitrite reductase from Hyphomicrobium denitrificans strain 1NES1 | Descriptor: | COPPER (II) ION, Copper-containing nitrite reductase | Authors: | Sasaki, D, Watanabe, T.F, Eady, R.R, Garratt, R.C, Antonyuk, S.V, Hasnain, S.S. | Deposit date: | 2019-11-14 | Release date: | 2020-06-10 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structures of substrate- and product-bound forms of a multi-domain copper nitrite reductase shed light on the role of domain tethering in protein complexes. Iucrj, 7, 2020
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6SW6
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![BU of 6sw6 by Molmil](/molmil-images/mine/6sw6) | |
6THE
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![BU of 6the by Molmil](/molmil-images/mine/6the) | Crystal structure of core domain of four-domain heme-cupredoxin-Cu nitrite reductase from Bradyrhizobium sp. ORS 375 | Descriptor: | CHLORIDE ION, COPPER (II) ION, Copper-containing nitrite reductase, ... | Authors: | Sasaki, D, Watanabe, T.F, Eady, R.R, Garratt, R.C, Antonyuk, S.V, Hasnain, S.S. | Deposit date: | 2019-11-20 | Release date: | 2020-04-22 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.87 Å) | Cite: | Reverse protein engineering of a novel 4-domain copper nitrite reductase reveals functional regulation by protein-protein interaction. Febs J., 288, 2021
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5OCF
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![BU of 5ocf by Molmil](/molmil-images/mine/5ocf) | Crystal structure of nitric oxide bound to three-domain heme-Cu nitrite reductase from Ralstonia pickettii | Descriptor: | COPPER (II) ION, HEME C, NITRIC OXIDE, ... | Authors: | Dong, J, Sasaki, D, Eady, R, Antonyuk, S.V, Hasnain, S.S. | Deposit date: | 2017-06-30 | Release date: | 2018-06-27 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Activation of redox tyrosine switch is required for ligand binding at the catalytic site in heme-cu nitrite reductases To be published
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5OCB
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![BU of 5ocb by Molmil](/molmil-images/mine/5ocb) | Crystal structure of nitric oxide bound D97N mutant of three-domain heme-Cu nitrite reductase from Ralstonia pickettii | Descriptor: | COPPER (II) ION, HEME C, NITRIC OXIDE, ... | Authors: | Dong, J, Sasaki, D, Eady, R, Antonyuk, S.V, Hasnain, S.S. | Deposit date: | 2017-06-30 | Release date: | 2018-06-27 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Activation of redox tyrosine switch is required for ligand binding at the catalytic site in heme-cu nitrite reductases To be published
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6THF
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![BU of 6thf by Molmil](/molmil-images/mine/6thf) | Crystal structure of two-domain Cu nitrite reductase from Bradyrhizobium sp. ORS 375 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, COPPER (II) ION, Copper-containing nitrite reductase, ... | Authors: | Sasaki, D, Watanabe, T.F, Eady, R.R, Garratt, R.C, Antonyuk, S.V, Hasnain, S.S. | Deposit date: | 2019-11-20 | Release date: | 2020-04-22 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Reverse protein engineering of a novel 4-domain copper nitrite reductase reveals functional regulation by protein-protein interaction. Febs J., 288, 2021
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5ONY
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![BU of 5ony by Molmil](/molmil-images/mine/5ony) | As-isolated resting state copper nitrite reductase from Achromobacter xylosoxidans | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, COPPER (II) ION, Copper-containing nitrite reductase, ... | Authors: | Halsted, T.P, Yamashita, K, Hirata, K, Ago, H, Ueno, G, Tosha, T, Eady, R.R, Antonyuk, S.V, Yamamoto, M, Hasnain, S.S. | Deposit date: | 2017-08-04 | Release date: | 2017-11-29 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | An unprecedented dioxygen species revealed by serial femtosecond rotation crystallography in copper nitrite reductase. IUCrJ, 5, 2018
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5ONX
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![BU of 5onx by Molmil](/molmil-images/mine/5onx) | Resting state copper nitrite reductase determined by serial femtosecond rotation crystallography | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, COPPER (II) ION, Copper-containing nitrite reductase, ... | Authors: | Halsted, T.P, Yamashita, K, Hirata, K, Ago, H, Ueno, G, Tosha, T, Eady, R.R, Antonyuk, S.V, Yamamoto, M, Hasnain, S.S. | Deposit date: | 2017-08-04 | Release date: | 2017-11-29 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | An unprecedented dioxygen species revealed by serial femtosecond rotation crystallography in copper nitrite reductase. IUCrJ, 5, 2018
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5OKD
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![BU of 5okd by Molmil](/molmil-images/mine/5okd) | Crystal structure of bovine Cytochrome bc1 in complex with inhibitor SCR0911. | Descriptor: | 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ... | Authors: | Amporndanai, K, O'Neill, P.M, Hasnain, S.S, Antonyuk, S.V. | Deposit date: | 2017-07-25 | Release date: | 2018-02-28 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | X-ray and cryo-EM structures of inhibitor-bound cytochromebc1complexes for structure-based drug discovery. IUCrJ, 5, 2018
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2PCR
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![BU of 2pcr by Molmil](/molmil-images/mine/2pcr) | Crystal structure of Myo-inositol-1(or 4)-monophosphatase (aq_1983) from Aquifex Aeolicus VF5 | Descriptor: | Inositol-1-monophosphatase | Authors: | Jeyakanthan, J, Gayathri, D, Velmurugan, D, Agari, Y, Bessho, Y, Ellis, M.J, Antonyuk, S.V, Strange, R.W, Hasnain, S.S, Ebihara, A, Kuramitsu, S, Shinkai, A, Shiro, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-30 | Release date: | 2007-10-02 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of Myo-inositol-1(or 4)-monophosphatase (aq_1983) from Aquifex Aeolicus VF5 To be Published
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1NDT
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![BU of 1ndt by Molmil](/molmil-images/mine/1ndt) | NITRITE REDUCTASE FROM ALCALIGENES XYLOSOXIDANS | Descriptor: | CHLORIDE ION, COPPER (II) ION, PROTEIN (NITRITE REDUCTASE) | Authors: | Dodd, F.E, Vanbeeumen, J, Eady, R.R, Hasnain, S.S. | Deposit date: | 1998-10-28 | Release date: | 1998-11-04 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | X-ray structure of a blue-copper nitrite reductase in two crystal forms. The nature of the copper sites, mode of substrate binding and recognition by redox partner. J.Mol.Biol., 282, 1998
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1NDS
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![BU of 1nds by Molmil](/molmil-images/mine/1nds) | CRYSTALLOGRAPHIC STRUCTURE OF A SUBSTRATE BOUND BLUE COPPER NITRITE REDUCTASE FROM ALCALIGENES XYLOSOXIDANS | Descriptor: | COPPER (II) ION, NITRITE ION, NITRITE REDUCTASE | Authors: | Dodd, F.E, Hasnain, S.S, Abraham, Z.H.L, Eady, R.R, Smith, B.E. | Deposit date: | 1997-01-23 | Release date: | 1997-07-07 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structures of a blue-copper nitrite reductase and its substrate-bound complex. Acta Crystallogr.,Sect.D, 53, 1997
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1NDR
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![BU of 1ndr by Molmil](/molmil-images/mine/1ndr) | CRYSTALLOGRAPHIC STRUCTURE OF A BLUE COPPER NITRITE REDUCTASE FROM ALCALIGENES XYLOSOXIDANS | Descriptor: | COPPER (II) ION, NITRITE REDUCTASE | Authors: | Dodd, F.E, Hasnain, S.S, Abraham, Z.H.L, Eady, R.R, Smith, B.E. | Deposit date: | 1997-01-23 | Release date: | 1997-07-07 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structures of a blue-copper nitrite reductase and its substrate-bound complex. Acta Crystallogr.,Sect.D, 53, 1997
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1OZU
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![BU of 1ozu by Molmil](/molmil-images/mine/1ozu) | Crystal Structure of Familial ALS Mutant S134N of human Cu,Zn Superoxide Dismutase (CuZnSOD) to 1.3A resolution | Descriptor: | SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION | Authors: | Elam, J.S, Taylor, A.B, Strange, R, Antonyuk, S, Doucette, P.A, Rodriguez, J.A, Hasnain, S.S, Hayward, L.J, Valentine, J.S, Yeates, T.O, Hart, P.J. | Deposit date: | 2003-04-09 | Release date: | 2003-05-27 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Amyloid-like Filaments and Water-filled Nanotubes Formed by SOD1 Mutant Proteins Linked to Familial ALS Nat.Struct.Biol., 10, 2003
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3ZTZ
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![BU of 3ztz by Molmil](/molmil-images/mine/3ztz) | Cytochrome c prime from alcaligenes xylosoxidans: carbon monooxide bound L16G variant at 1.05 A resolution: unrestraint refinement | Descriptor: | CARBON MONOXIDE, CYTOCHROME C', HEME C | Authors: | Antonyuk, S.V, Rustage, N, Eady, R.R, Hasnain, S.S. | Deposit date: | 2011-07-12 | Release date: | 2011-10-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Carbon Monoxide Poisoning is Prevented by the Energy Costs of Conformational Changes in Gas- Binding Haemproteins. Proc.Natl.Acad.Sci.USA, 108, 2011
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1Q0E
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![BU of 1q0e by Molmil](/molmil-images/mine/1q0e) | |
3ZQV
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![BU of 3zqv by Molmil](/molmil-images/mine/3zqv) | |
4A7U
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![BU of 4a7u by Molmil](/molmil-images/mine/4a7u) | Structure of human I113T SOD1 complexed with adrenaline in the p21 space group. | Descriptor: | ACETATE ION, COPPER (II) ION, L-EPINEPHRINE, ... | Authors: | Wright, G.S.A, Kershaw, N.M, Antonyuk, S.V, Strange, R.W, ONeil, P.M, Hasnain, S.S. | Deposit date: | 2011-11-14 | Release date: | 2012-11-28 | Last modified: | 2013-05-08 | Method: | X-RAY DIFFRACTION (0.98 Å) | Cite: | Ligand Binding and Aggregation of Pathogenic Sod1. Nat.Commun., 4, 2013
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4A7T
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![BU of 4a7t by Molmil](/molmil-images/mine/4a7t) | Structure of human I113T SOD1 mutant complexed with isoproteranol in the p21 space group | Descriptor: | ACETATE ION, COPPER (II) ION, ISOPRENALINE, ... | Authors: | Wright, G.S.A, Kershaw, N.M, Antonyuk, S.V, Strange, R.W, ONeil, P.M, Hasnain, S.S. | Deposit date: | 2011-11-14 | Release date: | 2012-11-28 | Last modified: | 2013-05-08 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Ligand Binding and Aggregation of Pathogenic Sod1. Nat.Commun., 4, 2013
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4A7Q
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![BU of 4a7q by Molmil](/molmil-images/mine/4a7q) | Structure of human I113T SOD1 mutant complexed with 4-(4-methyl-1,4- diazepan-1-yl)quinazoline in the p21 space group. | Descriptor: | 4-(4-METHYL-1,4-DIAZEPAN-1-YL)QUINAZOLINE, COPPER (II) ION, SULFATE ION, ... | Authors: | Wright, G.S.A, Kershaw, N.M, Antonyuk, S.V, Strange, R.W, ONeil, P.M, Hasnain, S.S. | Deposit date: | 2011-11-14 | Release date: | 2012-10-24 | Last modified: | 2013-08-28 | Method: | X-RAY DIFFRACTION (1.22 Å) | Cite: | X-Ray Crystallography and Computational Docking for the Detection and Development of Protein-Ligand Interactions. Curr.Med.Chem., 20, 2013
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1OEZ
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![BU of 1oez by Molmil](/molmil-images/mine/1oez) | Zn His46Arg mutant of Human Cu, Zn Superoxide Dismutase | Descriptor: | SULFATE ION, SUPEROXIDE DISMUTASE [CU-ZN], ZINC ION | Authors: | Strange, R.W, Antonyuk, S, Hough, M.A, Doucette, P, Rodriguez, J, Elam, J.S, Hart, P.J, Hayward, L.J, Valentine, J.S, Hasnain, S.S. | Deposit date: | 2003-04-02 | Release date: | 2003-05-29 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Amyloid-Like Filaments and Water-Filled Nanotubes Formed by Sod1 Mutant Proteins Linked to Familial Als Nat.Struct.Biol., 10, 2003
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4A7S
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![BU of 4a7s by Molmil](/molmil-images/mine/4a7s) | Structure of human I113T SOD1 mutant complexed with 5-Fluorouridine in the p21 space group | Descriptor: | 5-FLUOROURIDINE, ACETATE ION, COPPER (II) ION, ... | Authors: | Wright, G.S.A, Kershaw, N.M, Antonyuk, S.V, Strange, R.W, ONeil, P.M, Hasnain, S.S. | Deposit date: | 2011-11-14 | Release date: | 2012-12-05 | Last modified: | 2013-05-08 | Method: | X-RAY DIFFRACTION (1.06 Å) | Cite: | Ligand Binding and Aggregation of Pathogenic Sod1. Nat.Commun., 4, 2013
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4A7G
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![BU of 4a7g by Molmil](/molmil-images/mine/4a7g) | Structure of human I113T SOD1 mutant complexed with 4-methylpiperazin- 1-yl)quinazoline in the p21 space group. | Descriptor: | 4-(4-METHYLPIPERAZIN-1-YL)QUINAZOLINE, ACETATE ION, COPPER (II) ION, ... | Authors: | Wright, G.S.A, Kershaw, N.M, Sharma, R, Antonyuk, S.V, Strange, R.W, Berry, N.G, O'Neil, P.M, Hasnain, S.S. | Deposit date: | 2011-11-14 | Release date: | 2012-10-24 | Last modified: | 2019-10-09 | Method: | X-RAY DIFFRACTION (1.24 Å) | Cite: | X-ray crystallography and computational docking for the detection and development of protein-ligand interactions. Curr.Med.Chem., 20, 2013
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