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PDB: 127 件

3BBE
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M. jannaschii Nep1
分子名称: GLYCEROL, Ribosome biogenesis protein NEP1-like
著者Taylor, A.B, Meyer, B, Leal, B.Z, Kotter, P, Hart, P.J, Entian, K.-D, Wohnert, J.
登録日2007-11-09
公開日2008-02-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The crystal structure of Nep1 reveals an extended SPOUT-class methyltransferase fold and a pre-organized SAM-binding site.
Nucleic Acids Res., 36, 2008
3BBH
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M. jannaschii Nep1 complexed with Sinefungin
分子名称: GLYCEROL, Ribosome biogenesis protein NEP1-like, SINEFUNGIN
著者Taylor, A.B, Meyer, B, Leal, B.Z, Kotter, P, Hart, P.J, Entian, K.-D, Wohnert, J.
登録日2007-11-09
公開日2008-02-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The crystal structure of Nep1 reveals an extended SPOUT-class methyltransferase fold and a pre-organized SAM-binding site.
Nucleic Acids Res., 36, 2008
5VFE
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Synaptotagmin 1 C2A domain, lead-bound
分子名称: LEAD (II) ION, SULFATE ION, Synaptotagmin-1
著者Taylor, A.B, Hart, P.J, Igumenova, T.I.
登録日2017-04-07
公開日2018-04-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献High affinity interactions of Pb2+with synaptotagmin I.
Metallomics, 10, 2018
3C7N
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Structure of the Hsp110:Hsc70 Nucleotide Exchange Complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, CHLORIDE ION, ...
著者Schuermann, J.P, Jiang, J, Hart, P.J, Sousa, R.
登録日2008-02-07
公開日2008-05-27
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.115 Å)
主引用文献Structure of the Hsp110:Hsc70 nucleotide exchange machine
Mol.Cell, 31, 2008
3BLX
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Yeast Isocitrate Dehydrogenase (Apo Form)
分子名称: Isocitrate dehydrogenase [NAD] subunit 1, Isocitrate dehydrogenase [NAD] subunit 2
著者Taylor, A.B, Hu, G, Hart, P.J, McAlister-Henn, L.
登録日2007-12-11
公開日2008-02-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Allosteric Motions in Structures of Yeast NAD+-specific Isocitrate Dehydrogenase.
J.Biol.Chem., 283, 2008
3BLW
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Yeast Isocitrate Dehydrogenase with Citrate and AMP Bound in the Regulatory Subunits
分子名称: ADENOSINE MONOPHOSPHATE, CITRATE ANION, Isocitrate dehydrogenase [NAD] subunit 1, ...
著者Taylor, A.B, Hu, G, Hart, P.J, McAlister-Henn, L.
登録日2007-12-11
公開日2008-02-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献Allosteric Motions in Structures of Yeast NAD+-specific Isocitrate Dehydrogenase.
J.Biol.Chem., 283, 2008
3BLV
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Yeast Isocitrate Dehydrogenase with Citrate Bound in the Regulatory Subunits
分子名称: CITRATE ANION, Isocitrate dehydrogenase [NAD] subunit 1, Isocitrate dehydrogenase [NAD] subunit 2
著者Taylor, A.B, Hu, G, Hart, P.J, McAlister-Henn, L.
登録日2007-12-11
公開日2008-02-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Allosteric Motions in Structures of Yeast NAD+-specific Isocitrate Dehydrogenase.
J.Biol.Chem., 283, 2008
2H0R
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Structure of the Yeast Nicotinamidase Pnc1p
分子名称: Nicotinamidase, ZINC ION
著者Taylor, A.B, Hu, G, Hart, P.J, McAlister-Henn, L.
登録日2006-05-15
公開日2007-03-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of the yeast nicotinamidase Pnc1p.
Arch.Biochem.Biophys., 461, 2007
3CQQ
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Human SOD1 G85R Variant, Structure II
分子名称: ACETYL GROUP, Superoxide dismutase [Cu-Zn], ZINC ION
著者Cao, X, Antonyuk, S, Whitson, L.J, Taylor, A.B, Holloway, S.P, Strange, R.W, Doucette, P.A, Valentine, J.S, Tiwari, A, Hayward, L.J, Padua, S, Cohlberg, J.A, Hasnain, S.S, Hart, P.J.
登録日2008-04-03
公開日2008-04-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of the G85R Variant of SOD1 in Familial Amyotrophic Lateral Sclerosis.
J.Biol.Chem., 283, 2008
3CQP
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Human SOD1 G85R Variant, Structure I
分子名称: COPPER (II) ION, MALONATE ION, Superoxide dismutase [Cu-Zn], ...
著者Cao, X, Antonyuk, S, Seetharaman, S.V, Whitson, L.J, Taylor, A.B, Holloway, S.P, Strange, R.W, Doucette, P.A, Valentine, J.S, Tiwari, A, Hayward, L.J, Padua, S, Cohlberg, J.A, Hasnain, S.S, Hart, P.J.
登録日2008-04-03
公開日2008-04-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structures of the G85R Variant of SOD1 in Familial Amyotrophic Lateral Sclerosis.
J.Biol.Chem., 283, 2008
2LM3
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Structure of the rhesus monkey TRIM5alpha PRYSPRY domain
分子名称: Tripartite motif-containing protein 5
著者Biris, N, Yang, Y, Taylor, A.B, Tomashevski, A, Guo, M, Hart, P.J, Diaz-Griffero, F, Ivanov, D.N.
登録日2011-11-21
公開日2012-08-08
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure of the rhesus monkey TRIM5alpha PRYSPRY domain, the HIV capsid recognition module.
Proc.Natl.Acad.Sci.USA, 109, 2012
3GQF
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Structural and Biophysical Properties of the Pathogenic SOD1 Variant H46R/H48Q
分子名称: CALCIUM ION, Superoxide dismutase [Cu-Zn], ZINC ION
著者Winkler, D.D, Schuermann, J.P, Hart, P.J.
登録日2009-03-24
公開日2009-04-07
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural and biophysical properties of the pathogenic SOD1 variant H46R/H48Q.
Biochemistry, 48, 2009
3GTT
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Mouse SOD1
分子名称: Superoxide dismutase [Cu-Zn], ZINC ION
著者Seetharaman, S.V, Taylor, A.B, Hart, P.J.
登録日2009-03-28
公開日2010-09-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structures of mouse SOD1 and human/mouse SOD1 chimeras.
Arch.Biochem.Biophys., 503, 2010
3GZO
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HUMAN SOD1 G93A Variant
分子名称: COPPER (II) ION, GLYCEROL, MALONATE ION, ...
著者Galaleldeen, A, Taylor, A.B, Narayana, N, Whitson, L.J, Hart, P.J.
登録日2009-04-07
公開日2009-10-13
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and biophysical properties of metal-free pathogenic SOD1 mutants A4V and G93A.
Arch.Biochem.Biophys., 492, 2009
3H2Q
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Human SOD1 H80R variant, P21 crystal form
分子名称: SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION
著者Seetharaman, S.V, Winkler, D.D, Taylor, A.B, Cao, X, Whitson, L.J, Doucette, P.A, Valentine, J.S, Carroll, M.C, Culotta, V.C, Hart, P.J.
登録日2009-04-14
公開日2010-05-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structures of Pathogenic SOD1 Mutants H80R and D124V: Disrupted Zinc-binding and Compromised Post-translational Modification by the Copper Chaperone CCS
To be Published
3GZP
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HUMAN SOD1 G93A Metal-free Variant
分子名称: Superoxide dismutase [Cu-Zn]
著者Galaleldeen, A, Taylor, A.B, Whitson, L.J, Hart, P.J.
登録日2009-04-07
公開日2009-10-13
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural and biophysical properties of metal-free pathogenic SOD1 mutants A4V and G93A.
Arch.Biochem.Biophys., 492, 2009
3GZQ
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HUMAN SOD1 A4V Metal-free Variant
分子名称: SULFATE ION, Superoxide dismutase [Cu-Zn]
著者Galaleldeen, A, Taylor, A.B, Whitson, L.J, Hart, P.J.
登録日2009-04-07
公開日2009-10-13
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.401 Å)
主引用文献Structural and biophysical properties of metal-free pathogenic SOD1 mutants A4V and G93A.
Arch.Biochem.Biophys., 492, 2009
3H2P
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Human SOD1 D124V Variant
分子名称: ACETYL GROUP, MALONATE ION, Superoxide dismutase [Cu-Zn], ...
著者Seetharaman, S.V, Winkler, D.D, Taylor, A.B, Cao, X, Whitson, L.J, Doucette, P.A, Valentine, J.S, Carroll, M.C, Culotta, V.C, Hart, P.J.
登録日2009-04-14
公開日2010-05-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structures of Pathogenic SOD1 Mutants H80R and D124V: Disrupted Zinc-binding and Compromised Post-translational Modification by the Copper Chaperone CCS
To be Published
3GTV
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Human-mouse SOD1 chimera
分子名称: Superoxide dismutase [Cu-Zn], ZINC ION
著者Seetharaman, S.V, Taylor, A.B, Hart, P.J.
登録日2009-03-28
公開日2010-09-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structures of mouse SOD1 and human/mouse SOD1 chimeras.
Arch.Biochem.Biophys., 503, 2010
2NNX
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Crystal Structure of the H46R, H48Q double mutant of human [Cu-Zn] Superoxide Dismutase
分子名称: SULFATE ION, SUPEROXIDE DISMUTASE [CU-ZN], ZINC ION
著者Schuermann, J.P, Hart, P.J.
登録日2006-10-24
公開日2006-11-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Disease-associated mutations at copper ligand histidine residues of superoxide dismutase 1 diminish the binding of copper and compromise dimer stability
J.Biol.Chem., 282, 2007
4MCN
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Human SOD1 C57S Mutant, Metal-free
分子名称: SULFATE ION, Superoxide dismutase [Cu-Zn]
著者Sea, K, Sohn, S.H, Durazo, A, Sheng, Y, Shaw, B, Cao, X, Taylor, A.B, Whitson, L.J, Holloway, S.P, Hart, P.J, Cabelli, D.E, Gralla, E.B, Valentine, J.S.
登録日2013-08-21
公開日2014-08-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Insights into the role of the unusual disulfide bond in copper-zinc superoxide dismutase.
J.Biol.Chem., 290, 2015
4N3U
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Candida albicans Superoxide Dismutase 5 (SOD5), Cu(II)
分子名称: CITRATE ANION, COPPER (II) ION, Potential secreted Cu/Zn superoxide dismutase
著者Galaleldeen, A, Taylor, A.B, Waninger-Saroni, J.J, Holloway, S.P, Hart, P.J.
登録日2013-10-07
公開日2014-04-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Candida albicans SOD5 represents the prototype of an unprecedented class of Cu-only superoxide dismutases required for pathogen defense.
Proc.Natl.Acad.Sci.USA, 111, 2014
4MUB
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Schistosoma mansoni (Blood Fluke) Sulfotransferase/Oxamniquine Complex
分子名称: ADENOSINE-3'-5'-DIPHOSPHATE, Sulfotransferase, {(2S)-7-nitro-2-[(propan-2-ylamino)methyl]-1,2,3,4-tetrahydroquinolin-6-yl}methanol
著者Valentim, C.L.L, Cioli, D, Chevalier, F.D, Cao, X, Taylor, A.B, Holloway, S.P, Pica-Mattoccia, L, Guidi, A, Basso, A, Tsai, I.J, Berriman, M, Carvalho-Queiroz, C, Almeida, M, Aguilar, H, Frantz, D.E, Hart, P.J, Anderson, T.J.C, LoVerde, P.T.
登録日2013-09-21
公開日2013-12-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Genetic and molecular basis of drug resistance and species-specific drug action in schistosome parasites.
Science, 342, 2013
4N3T
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Candida albicans Superoxide Dismutase 5 (SOD5), Cu(I)
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, COPPER (I) ION, Potential secreted Cu/Zn superoxide dismutase, ...
著者Galaleldeen, A, Taylor, A.B, Waninger-Saroni, J.J, Holloway, S.P, Hart, P.J.
登録日2013-10-07
公開日2014-04-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Candida albicans SOD5 represents the prototype of an unprecedented class of Cu-only superoxide dismutases required for pathogen defense.
Proc.Natl.Acad.Sci.USA, 111, 2014
4MUA
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Schistosoma mansoni (Blood Fluke) Sulfotransferase
分子名称: ADENOSINE-3'-5'-DIPHOSPHATE, SODIUM ION, Sulfotransferase
著者Valentim, C.L.L, Cioli, D, Chevalier, F.D, Cao, X, Taylor, A.B, Holloway, S.P, Pica-Mattoccia, L, Guidi, A, Basso, A, Tsai, I.J, Berriman, M, Carvalho-Queiroz, C, Almeida, M, Aguilar, H, Frantz, D.E, Hart, P.J, Anderson, T.J.C, LoVerde, P.T.
登録日2013-09-21
公開日2013-12-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Genetic and molecular basis of drug resistance and species-specific drug action in schistosome parasites.
Science, 342, 2013

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