4BK5
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![BU of 4bk5 by Molmil](/molmil-images/mine/4bk5) | crystal structure of the human EphA4 ectodomain in complex with human ephrin A5 (amine-methylated sample) | Descriptor: | EPHRIN TYPE-A RECEPTOR 4, EPHRIN-A5 | Authors: | Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A.R, Klein, R, Jones, E.Y. | Deposit date: | 2013-04-22 | Release date: | 2013-07-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses Nat.Struct.Mol.Biol., 20, 2013
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4BKF
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![BU of 4bkf by Molmil](/molmil-images/mine/4bkf) | crystal structure of the human EphA4 ectodomain in complex with human ephrinB3 | Descriptor: | EPHRIN TYPE-A RECEPTOR 4, EPHRIN-B3 | Authors: | Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A.R, Klein, R, Jones, E.Y. | Deposit date: | 2013-04-24 | Release date: | 2013-07-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (4.65 Å) | Cite: | Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses Nat.Struct.Mol.Biol., 20, 2013
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4C53
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![BU of 4c53 by Molmil](/molmil-images/mine/4c53) | Crystal Structure of Guanarito virus GP2 in the post-fusion conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PRE-GLYCOPROTEIN POLYPROTEIN GP COMPLEX, ... | Authors: | Parsy, M, Huiskonen, J.T, Harlos, K, Bowden, T.A. | Deposit date: | 2013-09-10 | Release date: | 2013-10-02 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (4.14 Å) | Cite: | Crystal Structure of Venezuelan Hemorrhagic Fever Virus Fusion Glycoprotein Reveals a Class 1 Post-Fusion Architecture with Extensive Glycosylation. J.Virol., 87, 2013
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4CNC
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![BU of 4cnc by Molmil](/molmil-images/mine/4cnc) | Crystal structure of human 5T4 (Wnt-activated inhibitory factor 1, Trophoblast glycoprotein) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... | Authors: | Zhao, Y, Malinauskas, T, Harlos, K, Jones, E.Y. | Deposit date: | 2014-01-21 | Release date: | 2014-02-26 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Structural Insights Into the Inhibition of Wnt Signaling by Cancer Antigen 5T4/Wnt-Activated Inhibitory Factor 1. Structure, 22, 2014
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4CNM
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![BU of 4cnm by Molmil](/molmil-images/mine/4cnm) | Crystal structure of human 5T4 (Wnt-activated inhibitory factor 1, Trophoblast glycoprotein) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, ... | Authors: | Zhao, Y, Malinauskas, T, Harlos, K, Jones, E.Y. | Deposit date: | 2014-01-23 | Release date: | 2014-02-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural Insights Into the Inhibition of Wnt Signaling by Cancer Antigen 5T4/Wnt-Activated Inhibitory Factor 1. Structure, 22, 2014
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4CS8
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![BU of 4cs8 by Molmil](/molmil-images/mine/4cs8) | Crystal structure of the asymmetric human metapneumovirus M2-1 tetramer, form 2 | Descriptor: | M2-1, ZINC ION | Authors: | Leyrat, C, Renner, M, Harlos, K, Grimes, J.M. | Deposit date: | 2014-03-05 | Release date: | 2014-05-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Drastic Changes in Conformational Dynamics of the Antiterminator M2-1 Regulate Transcription Efficiency in Pneumovirinae. Elife, 3, 2014
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4CS7
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![BU of 4cs7 by Molmil](/molmil-images/mine/4cs7) | Crystal structure of the asymmetric human metapneumovirus M2-1 tetramer, form 1 | Descriptor: | M2-1, ZINC ION | Authors: | Leyrat, C, Renner, M, Harlos, K, Grimes, J.M. | Deposit date: | 2014-03-05 | Release date: | 2014-05-28 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Drastic Changes in Conformational Dynamics of the Antiterminator M2-1 Regulate Transcription Efficiency in Pneumovirinae. Elife, 3, 2014
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4CS9
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![BU of 4cs9 by Molmil](/molmil-images/mine/4cs9) | Crystal structure of the asymmetric human metapneumovirus M2-1 tetramer bound to adenosine monophosphate | Descriptor: | ADENOSINE MONOPHOSPHATE, M2-1, ZINC ION | Authors: | Leyrat, C, Renner, M, Harlos, K, Grimes, J.M. | Deposit date: | 2014-03-05 | Release date: | 2014-05-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Drastic Changes in Conformational Dynamics of the Antiterminator M2-1 Regulate Transcription Efficiency in Pneumovirinae. Elife, 3, 2014
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2UUX
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![BU of 2uux by Molmil](/molmil-images/mine/2uux) | Structure of the tryptase inhibitor TdPI from a tick | Descriptor: | SULFATE ION, TRYPTASE INHIBITOR | Authors: | Siebold, C, Paesen, G.C, Harlos, K, Peacey, M.F, Nuttall, P.A, Stuart, D.I. | Deposit date: | 2007-03-08 | Release date: | 2007-04-03 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | A Tick Protein with a Modified Kunitz Fold Inhibits Human Tryptase. J.Mol.Biol., 368, 2007
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2UUY
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![BU of 2uuy by Molmil](/molmil-images/mine/2uuy) | Structure of a tick tryptase inhibitor in complex with bovine trypsin | Descriptor: | CALCIUM ION, CATIONIC TRYPSIN, CHLORIDE ION, ... | Authors: | Siebold, C, Paesen, G.C, Harlos, K, Peacey, M.F, Nuttall, P.A, Stuart, D.I. | Deposit date: | 2007-03-08 | Release date: | 2007-04-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | A Tick Protein with a Modified Kunitz Fold Inhibits Human Tryptase. J.Mol.Biol., 368, 2007
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2UVD
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![BU of 2uvd by Molmil](/molmil-images/mine/2uvd) | The crystal structure of a 3-oxoacyl-(acyl carrier protein) reductase from Bacillus anthracis (BA3989) | Descriptor: | 3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE | Authors: | Zaccai, N.R, Carter, L.G, Berrow, N.S, Sainsbury, S, Nettleship, J.E, Walter, T.S, Harlos, K, Owens, R.J, Wilson, K.S, Stuart, D.I, Esnouf, R.M, Oxford Protein Production Facility (OPPF), Structural Proteomics in Europe (SPINE) | Deposit date: | 2007-03-09 | Release date: | 2007-04-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure of a 3-Oxoacyl-(Acylcarrier Protein) Reductase (Ba3989) from Bacillus Anthracis at 2.4-A Resolution. Proteins: Struct., Funct., Bioinf., 70, 2008
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4BKA
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![BU of 4bka by Molmil](/molmil-images/mine/4bka) | crystal structure of the human EphA4 ectodomain in complex with human ephrin A5 | Descriptor: | EPHRIN TYPE-A RECEPTOR 4, EPHRIN-A5 | Authors: | Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A.R, Klein, R, Jones, E.Y. | Deposit date: | 2013-04-23 | Release date: | 2013-07-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (5.3 Å) | Cite: | Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses Nat.Struct.Mol.Biol., 20, 2013
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4BK4
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![BU of 4bk4 by Molmil](/molmil-images/mine/4bk4) | crystal structure of the human EphA4 ectodomain | Descriptor: | EPHRIN TYPE-A RECEPTOR 4 | Authors: | Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A.R, Klein, R, Jones, E.Y. | Deposit date: | 2013-04-22 | Release date: | 2013-07-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.65 Å) | Cite: | Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses Nat.Struct.Mol.Biol., 20, 2013
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2UV3
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![BU of 2uv3 by Molmil](/molmil-images/mine/2uv3) | Structure of the signal-regulatory protein (SIRP) alpha domain that binds CD47. | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SULFATE ION, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE SUBSTRATE 1 | Authors: | Hatherley, D, Harlos, K, Dunlop, D.C, Stuart, D.I, Barclay, A.N. | Deposit date: | 2007-03-08 | Release date: | 2007-03-27 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The Structure of the Macrophage Signal Regulatory Protein Alpha (Sirpalpha) Inhibitory Receptor Reveals a Binding Face Reminiscent of that Used by T Cell Receptors. J.Biol.Chem., 282, 2007
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4CSA
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![BU of 4csa by Molmil](/molmil-images/mine/4csa) | Crystal structure of the asymmetric human metapneumovirus M2-1 tetramer bound to a DNA 4-mer | Descriptor: | 5'-D(*AP*GP*TP*TP*AP)-3', GLYCEROL, M2-1, ... | Authors: | Leyrat, C, Renner, M, Harlos, K, Grimes, J.M. | Deposit date: | 2014-03-05 | Release date: | 2014-05-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Drastic Changes in Conformational Dynamics of the Antiterminator M2-1 Regulate Transcription Efficiency in Pneumovirinae. Elife, 3, 2014
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2VSC
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![BU of 2vsc by Molmil](/molmil-images/mine/2vsc) | Structure of the immunoglobulin-superfamily ectodomain of human CD47 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, LEUKOCYTE SURFACE ANTIGEN CD47, MAGNESIUM ION | Authors: | Hatherley, D, Graham, S.C, Turner, J, Harlos, K, Stuart, D.I, Barclay, A.N. | Deposit date: | 2008-04-22 | Release date: | 2008-08-12 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Paired Receptor Specificity Explained by Structures of Signal Regulatory Proteins Alone and Complexed with Cd47. Mol.Cell, 31, 2008
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2WFR
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![BU of 2wfr by Molmil](/molmil-images/mine/2wfr) | Crystal structure of the N-terminal signalling domain of human Dhh with calcium | Descriptor: | CALCIUM ION, DESERT HEDGEHOG PROTEIN N-PRODUCT, SULFATE ION, ... | Authors: | Bishop, B, Aricescu, A.R, Harlos, K, O'Callaghan, C.A, Jones, E.Y, Siebold, C. | Deposit date: | 2009-04-14 | Release date: | 2009-06-30 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip Nat.Struct.Mol.Biol., 16, 2009
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2WAH
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![BU of 2wah by Molmil](/molmil-images/mine/2wah) | Crystal Structure of an IgG1 Fc Glycoform (Man9GlcNAc2) | Descriptor: | IG GAMMA-1 CHAIN C REGION, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Crispin, M, Bowden, T.A, Coles, C.H, Harlos, K, Aricescu, A.R, Harvey, D.J, Stuart, D.I, Jones, E.Y. | Deposit date: | 2009-02-06 | Release date: | 2009-03-10 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Carbohydrate and Domain Architecture of an Immature Antibody Glycoform Exhibiting Enhanced Effector Functions J.Mol.Biol., 387, 2009
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2W8X
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![BU of 2w8x by Molmil](/molmil-images/mine/2w8x) | Structure of the tick ion-channel modulator Ra-KLP | Descriptor: | ACETATE ION, GLYCEROL, IMIDAZOLE, ... | Authors: | Paesen, G.C, Siebold, C, Dallas, M, Peers, C, Harlos, K, Nuttall, P.A, Nunn, M.A, Stuart, D.I, Esnouf, R.M. | Deposit date: | 2009-01-20 | Release date: | 2009-05-05 | Last modified: | 2017-06-28 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | An Ion-Channel Modulator from the Saliva of the Brown Ear Tick Has a Highly Modified Kunitz/Bpti Structure. J.Mol.Biol., 389, 2009
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3ZMN
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![BU of 3zmn by Molmil](/molmil-images/mine/3zmn) | VP17, a capsid protein of bacteriophage P23-77 | Descriptor: | VP17 | Authors: | Rissanen, I, Grimes, J.M, Pawlowski, A, Mantynen, S, Harlos, K, Bamford, J.K.H, Stuart, D.I. | Deposit date: | 2013-02-11 | Release date: | 2013-05-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Bacteriophage P23-77 Capsid Protein Structures Reveal the Archetype of an Ancient Branch from a Major Virus Lineage. Structure, 21, 2013
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4BXT
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![BU of 4bxt by Molmil](/molmil-images/mine/4bxt) | |
2WG3
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![BU of 2wg3 by Molmil](/molmil-images/mine/2wg3) | Crystal structure of the complex between human hedgehog-interacting protein HIP and desert hedgehog without calcium | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, DESERT HEDGEHOG PROTEIN N-PRODUCT, ... | Authors: | Bishop, B, Aricescu, A.R, Harlos, K, O'Callaghan, C.A, Jones, E.Y, Siebold, C. | Deposit date: | 2009-04-15 | Release date: | 2009-06-30 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip Nat.Struct.Mol.Biol., 16, 2009
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2WFT
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![BU of 2wft by Molmil](/molmil-images/mine/2wft) | Crystal structure of the human HIP ectodomain | Descriptor: | CHLORIDE ION, HEDGEHOG-INTERACTING PROTEIN, SODIUM ION | Authors: | Bishop, B, Aricescu, A.R, Harlos, K, O'Callaghan, C.A, Jones, E.Y, Siebold, C. | Deposit date: | 2009-04-15 | Release date: | 2009-06-30 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip Nat.Struct.Mol.Biol., 16, 2009
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2WFQ
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![BU of 2wfq by Molmil](/molmil-images/mine/2wfq) | Crystal structure of the N-terminal signalling domain of human Dhh without calcium | Descriptor: | DESERT HEDGEHOG PROTEIN N-PRODUCT, SULFATE ION, ZINC ION | Authors: | Bishop, B, Aricescu, A.R, Harlos, K, O'Callaghan, C.A, Jones, E.Y, Siebold, C. | Deposit date: | 2009-04-14 | Release date: | 2009-06-30 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip Nat.Struct.Mol.Biol., 16, 2009
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2WFX
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![BU of 2wfx by Molmil](/molmil-images/mine/2wfx) | Crystal structure of the complex between human hedgehog-interacting protein HIP and Sonic Hedgehog in the presence of calcium | Descriptor: | CALCIUM ION, HEDGEHOG-INTERACTING PROTEIN, SODIUM ION, ... | Authors: | Bishop, B, Aricescu, A.R, Harlos, K, O'Callaghan, C.A, Jones, E.Y, Siebold, C. | Deposit date: | 2009-04-15 | Release date: | 2009-06-30 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip Nat.Struct.Mol.Biol., 16, 2009
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