2XBO
 
 | | Equine Rhinitis A Virus in Complex with its Sialic Acid Receptor | | Descriptor: | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, P1 | | Authors: | Fry, E.E, Tuthill, T.J, Harlos, K, Walter, T.S, Rowlands, D.J, Stuart, D.I. | | Deposit date: | 2010-04-14 | | Release date: | 2010-09-22 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (4 Å) | | Cite: | The Crystal Structure of Equine Rhinitis a Virus in Complex with its Sialic Acid Receptor.
J.Gen.Virol., 91, 2010
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2WG4
 | | Crystal structure of the complex between human hedgehog-interacting protein HIP and sonic hedgehog without calcium | | Descriptor: | HEDGEHOG-INTERACTING PROTEIN, SODIUM ION, SONIC HEDGEHOG PROTEIN N-PRODUCT, ... | | Authors: | Bishop, B, Aricescu, A.R, Harlos, K, O'Callaghan, C.A, Jones, E.Y, Siebold, C. | | Deposit date: | 2009-04-15 | | Release date: | 2009-06-30 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3.15 Å) | | Cite: | Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip
Nat.Struct.Mol.Biol., 16, 2009
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2WFF
 | | Equine Rhinitis A Virus | | Descriptor: | P1 | | Authors: | Fry, E.E, Tuthill, T.J, Harlos, K, Walter, T.S, Knowles, N.J, Gropelli, E, Rowlands, D.J, Stuart, D.I. | | Deposit date: | 2009-04-05 | | Release date: | 2010-05-05 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (4 Å) | | Cite: | Equine Rhinitis a Virus and its Low Ph Empty Particle: Clues Towards an Aphthovirus Entry Mechanism?
Plos Pathog., 5, 2009
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2X10
 | | Crystal structure of the complete EphA2 ectodomain | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, EPHRIN TYPE-A RECEPTOR 2 | | Authors: | Seiradake, E, Harlos, K, Sutton, G, Aricescu, A.R, Jones, E.Y. | | Deposit date: | 2009-12-21 | | Release date: | 2010-03-16 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | An Extracellular Steric Seeding Mechanism for Eph-Ephrin Signalling Platform Assembly
Nat.Struct.Mol.Biol., 17, 2010
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2X46
 | | Crystal Structure of SeMet Arg r 1 | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ALLERGEN ARG R 1 | | Authors: | Paesen, G.C, Siebold, C, Syme, N, Harlos, K, Graham, S.C, Hilger, C, Homans, S.W, Hentges, F, Stuart, D.I. | | Deposit date: | 2010-01-28 | | Release date: | 2011-02-09 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1 Å) | | Cite: | Crystal Structure of the Allergen Arg R 1, a Histamine-Binding Lipocalin from a Soft Tick
To be Published
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1H4I
 | | Methylobacterium extorquens methanol dehydrogenase | | Descriptor: | CALCIUM ION, METHANOL DEHYDROGENASE SUBUNIT 1, METHANOL DEHYDROGENASE SUBUNIT 2, ... | | Authors: | Ghosh, M, Anthony, C, Harlos, K, Goodwin, M.G, Blake, C. | | Deposit date: | 2001-05-11 | | Release date: | 2001-06-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | The Refined Structure of the Quinoprotein Methanol Dehydrogenase from Methylobacterium Extorquens at 1.94 A.
Structure, 3, 1995
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1GP0
 | | Human IGF2R domain 11 | | Descriptor: | CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR, SULFATE ION | | Authors: | Brown, J, Esnouf, R.M, Jones, M.A, Linnell, J, Harlos, K, Hassan, A.B, Jones, E.Y. | | Deposit date: | 2001-10-29 | | Release date: | 2002-02-28 | | Last modified: | 2019-04-10 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structure of a Functional Igf2R Fragment Determined from the Anomalous Scattering of Sulfur
Embo J., 21, 2002
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1GP3
 | | Human IGF2R domain 11 | | Descriptor: | CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR | | Authors: | Brown, J, Esnouf, R.M, Jones, M.A, Linnell, J, Harlos, K, Hassan, A.B, Jones, E.Y. | | Deposit date: | 2001-10-29 | | Release date: | 2002-02-28 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structure of a Functional Igf2R Fragment Determined from the Anomalous Scattering of Sulfur
Embo J., 21, 2002
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1GZP
 | | CD1b in complex with GM2 ganglioside | | Descriptor: | B2-MICROGLOBULIN, DOCOSANE, DODECANE, ... | | Authors: | Gadola, S.D, Zaccai, N.R, Harlos, K, Shepherd, D, Ritter, G, Schmidt, R.R, Jones, E.Y, Cerundolo, V. | | Deposit date: | 2002-05-24 | | Release date: | 2002-07-31 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure of human CD1b with bound ligands at 2.3 A, a maze for alkyl chains.
Nat. Immunol., 3, 2002
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2X11
 | | Crystal structure of the complete EphA2 ectodomain in complex with ephrin A5 receptor binding domain | | Descriptor: | EPHRIN TYPE-A RECEPTOR 2, EPHRIN-A5 | | Authors: | Seiradake, E, Harlos, K, Sutton, G, Aricescu, A.R, Jones, E.Y. | | Deposit date: | 2009-12-21 | | Release date: | 2010-03-16 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (4.83 Å) | | Cite: | An Extracellular Steric Seeding Mechanism for Eph-Ephrin Signalling Platform Assembly
Nat.Struct.Mol.Biol., 17, 2010
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1GZQ
 | | CD1b in complex with Phophatidylinositol | | Descriptor: | 2-[(HYDROXY{[(2R,3R,5S,6R)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL]OXY}PHOSPHORYL)OXY]-1-[(PALMITOYLOXY)METHYL]ETHYL HEPTADECANOATE, B2-MICROGLOBULIN, DOCOSANE, ... | | Authors: | Gadola, S.D, Zaccai, N.R, Harlos, K, Shepherd, D, Ritter, G, Schmidt, R.R, Jones, E.Y, Cerundolo, V. | | Deposit date: | 2002-05-24 | | Release date: | 2002-07-31 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.26 Å) | | Cite: | Structure of Human Cd1B with Bound Ligands at 2.3 A, a Maze for Alkyl Chains
Nat.Immunol., 3, 2002
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2WNG
 | | complete extracellular structure of human signal regulatory protein (SIRP) alpha | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE SUBSTRATE 1 | | Authors: | Hatherley, D, Graham, S.C, Harlos, K, Stuart, D.I, Barclay, A.N. | | Deposit date: | 2009-07-09 | | Release date: | 2009-07-21 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.49 Å) | | Cite: | Structure of Signal-Regulatory Protein Alpha: A Link to Antigen Receptor Evolution.
J.Biol.Chem., 284, 2009
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2WJW
 | | Crystal structure of the human ionotropic glutamate receptor GluR2 ATD region at 1.8 A resolution | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CHLORIDE ION, ... | | Authors: | Clayton, A, Siebold, C, Gilbert, R.J.C, Sutton, G.C, Harlos, K, McIlhinney, R.A.J, Jones, E.Y, Aricescu, A.R. | | Deposit date: | 2009-06-01 | | Release date: | 2009-08-18 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal Structure of the Glur2 Amino-Terminal Domain Provides Insights Into the Architecture and Assembly of Ionotropic Glutamate Receptors.
J.Mol.Biol., 392, 2009
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2WS9
 | | Equine Rhinitis A Virus at Low pH | | Descriptor: | P1 | | Authors: | Fry, E.E, Tuthill, T.J, Harlos, K, Walter, T.S, Knowles, N.J, Gropelli, E, Rowlands, D.J, Stuart, D.I. | | Deposit date: | 2009-09-04 | | Release date: | 2010-08-25 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Equine Rhinitis a Virus and its Low Ph Empty Particle: Clues Towards an Aphthovirus Entry Mechanism?
Plos Pathog., 5, 2009
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2X45
 | | Crystal Structure of Arg r 1 in complex with histamine | | Descriptor: | ALLERGEN ARG R 1, HISTAMINE | | Authors: | Paesen, G.C, Siebold, C, Syme, N, Harlos, K, Graham, S.C, Hilger, C, Homans, S.W, Hentges, F, Stuart, D.I. | | Deposit date: | 2010-01-28 | | Release date: | 2011-02-09 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Crystal Structure of the Allergen Arg R 1, a Histamine-Binding Lipocalin from a Soft Tick
To be Published
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2WJX
 | | Crystal structure of the human ionotropic glutamate receptor GluR2 ATD region at 4.1 A resolution | | Descriptor: | GLUTAMATE RECEPTOR 2 | | Authors: | Clayton, A, Siebold, C, Gilbert, R.J.C, Sutton, G.C, Harlos, K, McIlhinney, R.A.J, Jones, E.Y, Aricescu, A.R. | | Deposit date: | 2009-06-01 | | Release date: | 2009-08-18 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (4.1 Å) | | Cite: | Crystal Structure of the Glur2 Amino-Terminal Domain Provides Insights Into the Architecture and Assembly of Ionotropic Glutamate Receptors.
J.Mol.Biol., 392, 2009
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1IPS
 | | ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (MANGANESE COMPLEX) | | Descriptor: | ISOPENICILLIN N SYNTHASE, MANGANESE (II) ION | | Authors: | Roach, P.L, Clifton, I.J, Fulop, V, Harlos, K, Barton, G.J, Hajdu, J, Andersson, I, Schofield, C.J, Baldwin, J.E. | | Deposit date: | 1997-03-21 | | Release date: | 1998-03-25 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of isopenicillin N synthase is the first from a new structural family of enzymes.
Nature, 375, 1995
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7BY6
 | | Plasmodium vivax cytoplasmic Phenylalanyl-tRNA synthetase in complex with BRD1389 | | Descriptor: | (3S,4R,8R,9R,10S)-N-(4-cyclopropyloxyphenyl)-10-(methoxymethyl)-3,4-bis(oxidanyl)-9-[4-(2-phenylethynyl)phenyl]-1,6-diazabicyclo[6.2.0]decane-6-carboxamide, MAGNESIUM ION, Phenylalanyl-tRNA synthetase beta chain, ... | | Authors: | Malhotra, N, Manmohan, S, Harlos, K, Melillo, B, Schreiber, S.L, Manickam, Y, Sharma, S. | | Deposit date: | 2020-04-21 | | Release date: | 2020-11-04 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.997 Å) | | Cite: | Structural basis of malaria parasite phenylalanine tRNA-synthetase inhibition by bicyclic azetidines.
Nat Commun, 12, 2021
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7WAI
 | | Glutamyl-tRNA synthetase from Plasmodium falciparum (PfERS) | | Descriptor: | CHLORIDE ION, Glutamyl-tRNA synthetase | | Authors: | Sharma, V, Manickam, Y, Harlos, K, Sharma, A. | | Deposit date: | 2021-12-14 | | Release date: | 2022-12-21 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.105 Å) | | Cite: | Structural characterization of glutamyl-tRNA synthetase (GluRS) from Plasmodium falciparum.
Mol.Biochem.Parasitol., 253, 2022
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5L81
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