5TGP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5tgp by Molmil](/molmil-images/mine/5tgp) | |
4RHD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4rhd by Molmil](/molmil-images/mine/4rhd) | DNA Duplex with Novel ZP Base Pair | 分子名称: | DNA 9mer novel P nucleobase, DNA 9mer novel Z nucleobase, MAGNESIUM ION | 著者 | Zhang, W, Zhang, L, Benner, S, Huang, Z. | 登録日 | 2014-10-01 | 公開日 | 2015-07-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Evolution of functional six-nucleotide DNA. J.Am.Chem.Soc., 137, 2015
|
|
5UEG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ueg by Molmil](/molmil-images/mine/5ueg) | RNA primer-template complex with guanosine dinucleotide G(5')pppp(5')G ligand | 分子名称: | RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*GP*AP*CP*UP*UP*AP*AP*GP*UP*CP*G)-3'), [[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [[[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl] hydrogen phosphate | 著者 | Zhang, W, Tam, C.P, Szostak, J.W. | 登録日 | 2017-01-02 | 公開日 | 2017-07-05 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Insight into the mechanism of nonenzymatic RNA primer extension from the structure of an RNA-GpppG complex. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
5UEF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5uef by Molmil](/molmil-images/mine/5uef) | |
5UED
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ued by Molmil](/molmil-images/mine/5ued) | RNA primer-template complex with guanosine dinucleotide ligand G(5')pp(5')G | 分子名称: | RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*GP*AP*CP*UP*UP*AP*AP*GP*UP*CP*G)-3'), [[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate | 著者 | Zhang, W, Tam, C.P, Szostak, J.W. | 登録日 | 2017-01-01 | 公開日 | 2017-07-05 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Insight into the mechanism of nonenzymatic RNA primer extension from the structure of an RNA-GpppG complex. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
5UEE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5uee by Molmil](/molmil-images/mine/5uee) | |
3AL4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3al4 by Molmil](/molmil-images/mine/3al4) | Crystal structure of the swine-origin A (H1N1)-2009 influenza A virus hemagglutinin (HA) reveals similar antigenicity to that of the 1918 pandemic virus | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | 著者 | Zhang, W, Qi, J.X, Shi, Y, Li, Q, Yan, J.H, Gao, G.F. | 登録日 | 2010-07-22 | 公開日 | 2010-08-04 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.872 Å) | 主引用文献 | Crystal structure of the swine-origin A (H1N1)-2009 influenza A virus hemagglutinin (HA) reveals similar antigenicity to that of the 1918 pandemic virus Protein Cell, 1, 2010
|
|
8UZF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8uzf by Molmil](/molmil-images/mine/8uzf) | Crystal structure of chimeric RaTG13 RBD complexed with chimeric mouse ACE2 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhang, W, Shi, K, Aihara, H, Li, F. | 登録日 | 2023-11-15 | 公開日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (3.283 Å) | 主引用文献 | Crystal structure of chimeric RaTG13 RBD complexed with chimeric mouse ACE2 To Be Published
|
|
8UZE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8uze by Molmil](/molmil-images/mine/8uze) | Crystal structure of chimeric bat coronavirus BANAL-20-236 RBD complexed with chimeric mouse ACE2 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhang, W, Shi, K, Aihara, H, Li, F. | 登録日 | 2023-11-15 | 公開日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | 主引用文献 | Crystal structure of chimeric RBD complexed with chimeric mouse ACE2 To Be Published
|
|
5V0H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5v0h by Molmil](/molmil-images/mine/5v0h) | RNA duplex with 2-MeImpG analogue bound-one binding site | 分子名称: | 5'-O-[(S)-hydroxy(4-methyl-1H-imidazol-5-yl)phosphoryl]guanosine, MAGNESIUM ION, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*GP*G)-3') | 著者 | Zhang, W, Tam, C.P, Szostak, J.W. | 登録日 | 2017-02-28 | 公開日 | 2017-03-08 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide. J. Am. Chem. Soc., 140, 2018
|
|
5V0J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5v0j by Molmil](/molmil-images/mine/5v0j) | RNA duplex with 2-MeImpG analogue bound-2 binding sites | 分子名称: | 5'-O-[(S)-hydroxy(4-methyl-1H-imidazol-5-yl)phosphoryl]guanosine, MAGNESIUM ION, RNA (5'-R(*(LCC)P*(LCC)P*(LCA)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*U)-3') | 著者 | Zhang, W, Tam, C.P, Szostak, J.W. | 登録日 | 2017-02-28 | 公開日 | 2017-03-08 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide. J. Am. Chem. Soc., 140, 2018
|
|
5V0O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5v0o by Molmil](/molmil-images/mine/5v0o) | RNA hairpin structure containing 2-MeImpG analogue bound | 分子名称: | 5'-O-[(S)-hydroxy(4-methyl-1H-imidazol-5-yl)phosphoryl]guanosine, RNA (25-MER), RNA (5'-R(*GP*CP*AP*CP*CP*UP*CP*A)-3') | 著者 | Zhang, W, Tam, C.P, Szostak, J.W. | 登録日 | 2017-02-28 | 公開日 | 2018-02-21 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide. J. Am. Chem. Soc., 140, 2018
|
|
5UZ6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5uz6 by Molmil](/molmil-images/mine/5uz6) | |
5V9Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5v9z by Molmil](/molmil-images/mine/5v9z) | RNA hairpin structure containing 2-MeImpG analogue bound | 分子名称: | 5'-O-[(S)-hydroxy(4-methyl-1H-imidazol-5-yl)phosphoryl]guanosine, RNA (25-MER), RNA (5'-R(P*GP*CP*AP*CP*CP*UP*CP*A)-3') | 著者 | Zhang, W, Szostak, J.W. | 登録日 | 2017-03-24 | 公開日 | 2018-02-21 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide. J. Am. Chem. Soc., 140, 2018
|
|
5VCF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vcf by Molmil](/molmil-images/mine/5vcf) | |
5UX3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ux3 by Molmil](/molmil-images/mine/5ux3) | |
5V0K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5v0k by Molmil](/molmil-images/mine/5v0k) | |
2K9X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2k9x by Molmil](/molmil-images/mine/2k9x) | Solution structure of Urm1 from Trypanosoma brucei | 分子名称: | Uncharacterized protein | 著者 | Zhang, W, Zhang, J, Xu, C, Wang, T, Zhang, X, Tu, X. | 登録日 | 2008-10-27 | 公開日 | 2009-03-10 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of Urm1 from Trypanosoma brucei Proteins, 75, 2009
|
|
4IAA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4iaa by Molmil](/molmil-images/mine/4iaa) | Crystal structure of Ser/Thr kinase Pim1 in complex with thioridazine | 分子名称: | 10-{2-[(2R)-1-methylpiperidin-2-yl]ethyl}-2-(methylsulfanyl)-10H-phenothiazine, Serine/threonine-protein kinase pim-1 | 著者 | Zhang, W, Wan, X, Li, W, Xie, Y, Huang, N. | 登録日 | 2012-12-06 | 公開日 | 2013-12-18 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Crystal structure of Ser/Thr kinase Pim1 in complex with thioridazine To be Published
|
|
5WCO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wco by Molmil](/molmil-images/mine/5wco) | Matrix Protein (M1) of Infectious Salmon Anaemia Virus | 分子名称: | NS2 | 著者 | Zhang, W, Zheng, W, Toh, Y, Betancourt, M.A, Tu, J, Fan, Y, Vakharia, V, Liu, J, McNew, J.A, Jin, M, Tao, Y.J. | 登録日 | 2017-07-01 | 公開日 | 2017-08-16 | 最終更新日 | 2019-12-11 | 実験手法 | X-RAY DIFFRACTION (2.604 Å) | 主引用文献 | Crystal structure of an orthomyxovirus matrix protein reveals mechanisms for self-polymerization and membrane association. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
4I41
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4i41 by Molmil](/molmil-images/mine/4i41) | Crystal Structure of human Ser/Thr kinase Pim1 in complex with mitoxantrone | 分子名称: | 1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE, Serine/threonine-protein kinase pim-1 | 著者 | Zhang, W, Wan, X, Xie, Y, Huang, N. | 登録日 | 2012-11-27 | 公開日 | 2013-12-11 | 最終更新日 | 2019-07-17 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | A new target for an old drug: identifying mitoxantrone as a nanomolar inhibitor of PIM1 kinase via kinome-wide selectivity modeling. J. Med. Chem., 56, 2013
|
|
1OR4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1or4 by Molmil](/molmil-images/mine/1or4) | |
4ACS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4acs by Molmil](/molmil-images/mine/4acs) | Crystal structure of mutant GST A2-2 with enhanced catalytic efficiency with azathioprine | 分子名称: | GLUTATHIONE, GLUTATHIONE S-TRANSFERASE A2 | 著者 | Zhang, W, Moden, O, Tars, K, Mannervik, B. | 登録日 | 2011-12-19 | 公開日 | 2011-12-28 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure-based redesign of GST A2-2 for enhanced catalytic efficiency with azathioprine. Chem.Biol., 19, 2012
|
|
5ZHY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5zhy by Molmil](/molmil-images/mine/5zhy) | Structural characterization of the HCoV-229E fusion core | 分子名称: | Spike glycoprotein | 著者 | Zhang, W, Zheng, Q, Yan, M, Chen, X, Yang, H, Zhou, W, Rao, Z. | 登録日 | 2018-03-13 | 公開日 | 2018-06-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.441 Å) | 主引用文献 | Structural characterization of the HCoV-229E fusion core. Biochem. Biophys. Res. Commun., 497, 2018
|
|
1OR6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1or6 by Molmil](/molmil-images/mine/1or6) | |