5V0H

RNA duplex with 2-MeImpG analogue bound-one binding site

Summary for 5V0H

• Entry DOI: 10.2210/pdb5v0h/pdb
• Related: 5UX3 5UZ6 5V0J 5V0K 5V0O
• Descriptor: RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*GP*G)-3'), 5'-O-[(S)-hydroxy(4-methyl-1H-imidazol-5-yl)phosphoryl]guanosine, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: rna, analogue
• Biological source: synthetic construct
• Total number of polymer chains: 2
• Total formula weight: 10619.25

Authors

Zhang, W.,Tam, C.P.,Szostak, J.W. (deposition date: 2017-02-28, release date: 2017-03-08, Last modification date: 2023-10-04)

• Primary citation: Zhang, W.,Tam, C.P.,Zhou, L.,Oh, S.S.,Wang, J.,Szostak, J.W.; Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.; J. Am. Chem. Soc., 140:2829-2840, 2018; PubMed: 29411978; DOI: 10.1021/jacs.7b11750

Experimental method

X-RAY DIFFRACTION (1.9 Å)