8WJ3
 
 | | Cryo-EM structure of a bacterial protein | | 分子名称: | Helicase HerA central domain-containing protein, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | | 著者 | Yu, G, Liao, F, Li, X, Li, Z, Zhang, H. | | 登録日 | 2023-09-25 | | 公開日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (3.36 Å) | | 主引用文献 | Cryo-EM structure of a bacterial protein
To Be Published
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8WLD
 | | Cryo-EM structure of SIR2/HerA antiphage complex | | 分子名称: | Helicase HerA central domain-containing protein, SIR2-like domain-containing protein | | 著者 | Yu, G, Liao, F, Li, X, Li, Z, Zhang, H. | | 登録日 | 2023-09-29 | | 公開日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | | 主引用文献 | Cryo-EM structure of SIR2/HerA antiphage complex
To Be Published
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8WOC
 | | Cryo-EM structure of SIR2/HerA complex | | 分子名称: | Helicase HerA central domain-containing protein, SIR2-like domain-containing protein | | 著者 | Yu, G, Liao, F, Li, X, Li, Z, Zhang, H. | | 登録日 | 2023-10-07 | | 公開日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | | 主引用文献 | Cryo-EM structure of a bacterial protein
To Be Published
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8WOD
 | | Cryo-EM structure of SIR2/HerA complex | | 分子名称: | Helicase HerA central domain-containing protein, SIR2-like domain-containing protein | | 著者 | Yu, G, Liao, F, Li, X, Li, Z, Zhang, H. | | 登録日 | 2023-10-07 | | 公開日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (3.67 Å) | | 主引用文献 | Cryo-EM structure of a bacterial protein
To Be Published
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8WK0
 | | Cryo-EM structure of a bacterial protein | | 分子名称: | Helicase HerA central domain-containing protein, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | | 著者 | Yu, G, Liao, F, Li, X, Li, Z, Zhang, H. | | 登録日 | 2023-09-26 | | 公開日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (3.34 Å) | | 主引用文献 | Cryo-EM structure of a bacterial protein
To Be Published
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8WOF
 | | Cryo-EM structure of SIR2/HerA complex | | 分子名称: | Helicase HerA central domain-containing protein, SIR2-like domain-containing protein | | 著者 | Yu, G, Liao, F, Li, X, Li, Z, Zhang, H. | | 登録日 | 2023-10-07 | | 公開日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Cryo-EM structure of a bacterial protein
To Be Published
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5H48
 | | Crystal structure of Cbln1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cerebellin-1 | | 著者 | Zhong, C, Shen, J, Zhang, H, Ding, J. | | 登録日 | 2016-10-31 | | 公開日 | 2017-09-06 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Cbln1 and Cbln4 Are Structurally Similar but Differ in GluD2 Binding Interactions.
Cell Rep, 20, 2017
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5H4C
 | | Crystal structure of Cbln4 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Protein Cbln4 | | 著者 | Zhong, C, Shen, J, Zhang, H, Ding, J. | | 登録日 | 2016-10-31 | | 公開日 | 2017-09-06 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Cbln1 and Cbln4 Are Structurally Similar but Differ in GluD2 Binding Interactions.
Cell Rep, 20, 2017
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1NUR
 | | CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC NMN/NaMN ADENYLYLTRANSFERASE | | 分子名称: | FKSG76, SULFATE ION | | 著者 | Zhang, X, Kurnasov, O.V, Karthikeyan, S, Grishin, N.V, Osterman, A.L, Zhang, H. | | 登録日 | 2003-02-01 | | 公開日 | 2003-06-03 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | STRUCTURAL CHARACTERIZATION OF A HUMAN CYTOSOLIC NMN/NaMN
ADENYLYLTRANSFERASE AND IMPLICATION IN HUMAN NAD BIOSYNTHESIS
J.Biol.Chem., 278, 2003
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3FHQ
 | | Structure of endo-beta-N-acetylglucosaminidase A | | 分子名称: | 3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL, Endo-beta-N-acetylglucosaminidase, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose | | 著者 | Jie, Y, Li, L, Shaw, N, Li, Y, Song, J, Zhang, W, Xia, C, Zhang, R, Joachimiak, A, Zhang, H.-C, Wang, L.-X, Wang, P, Liu, Z.-J. | | 登録日 | 2008-12-10 | | 公開日 | 2009-05-05 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.452 Å) | | 主引用文献 | Structural basis and catalytic mechanism for the dual functional endo-beta-N-acetylglucosaminidase A
Plos One, 4, 2009
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1YSW
 | | Solution structure of the anti-apoptotic protein Bcl-2 complexed with an acyl-sulfonamide-based ligand | | 分子名称: | 3-NITRO-N-{4-[2-(2-PHENYLETHYL)-1,3-BENZOTHIAZOL-5-YL]BENZOYL}-4-{[2-(PHENYLSULFANYL)ETHYL]AMINO}BENZENESULFONAMIDE, Apoptosis regulator Bcl-2 | | 著者 | Oltersdorf, T, Elmore, S.W, Shoemaker, A.R, Armstrong, R.C, Augeri, D.J, Belli, B.A, Bruncko, M, Deckwerth, T.L, Dinges, J, Hajduk, P.J, Joseph, M.K, Kitada, S, Korsmeyer, S.J, Kunzer, A.R, Letai, A, Li, C, Mitten, M.J, Nettesheim, D.G, Ng, S, Nimmer, P.M, O'Connor, J.M, Oleksijew, A, Petros, A.M, Reed, J.C, Shen, W, Tahir, S.K, Thompson, C.B, Tomaselli, K.J, Wang, B, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H. | | 登録日 | 2005-02-09 | | 公開日 | 2005-06-07 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | An inhibitor of Bcl-2 family proteins induces regression of solid tumours
Nature, 435, 2005
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1YSG
 | | Solution Structure of the Anti-apoptotic Protein Bcl-xL in Complex with "SAR by NMR" Ligands | | 分子名称: | 4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID, 5,6,7,8-TETRAHYDRONAPHTHALEN-1-OL, Apoptosis regulator Bcl-X | | 著者 | Oltersdorf, T, Elmore, S.W, Shoemaker, A.R, Armstrong, R.C, Augeri, D.J, Belli, B.A, Bruncko, M, Deckwerth, T.L, Dinges, J, Hajduk, P.J, Joseph, M.K, Kitada, S, Korsmeyer, S.J, Kunzer, A.R, Letai, A, Li, C, Mitten, M.J, Nettesheim, D.G, Ng, S, Nimmer, P.M, O'Connor, J.M, Oleksijew, A, Petros, A.M, Reed, J.C, Shen, W, Tahir, S.K, Thompson, C.B, Tomaselli, K.J, Wang, B, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H. | | 登録日 | 2005-02-08 | | 公開日 | 2005-06-07 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | An inhibitor of Bcl-2 family proteins induces regression of solid tumours
Nature, 435, 2005
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1YSI
 | | Solution structure of the anti-apoptotic protein Bcl-xL in complex with an acyl-sulfonamide-based ligand | | 分子名称: | Apoptosis regulator Bcl-X, N-[(4'-FLUORO-1,1'-BIPHENYL-4-YL)CARBONYL]-3-NITRO-4-{[2-(PHENYLSULFANYL)ETHYL]AMINO}BENZENESULFONAMIDE | | 著者 | Oltersdorf, T, Elmore, S.W, Shoemaker, A.R, Armstrong, R.C, Augeri, D.J, Belli, B.A, Bruncko, M, Deckwerth, T.L, Dinges, J, Hajduk, P.J, Joseph, M.K, Kitada, S, Korsmeyer, S.J, Kunzer, A.R, Letai, A, Li, C, Mitten, M.J, Nettesheim, D.G, Ng, S, Nimmer, P.M, O'Connor, J.M, Oleksijew, A, Petros, A.M, Reed, J.C, Shen, W, Tahir, S.K, Thompson, C.B, Tomaselli, K.J, Wang, B, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H. | | 登録日 | 2005-02-08 | | 公開日 | 2005-06-07 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | An inhibitor of Bcl-2 family proteins induces regression of solid tumours
Nature, 435, 2005
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1YSX
 | | Solution structure of domain 3 from human serum albumin complexed to an anti-apoptotic ligand directed against Bcl-xL and Bcl-2 | | 分子名称: | 4-({2-[(2,4-DIMETHYLPHENYL)SULFANYL]ETHYL}AMINO)-N-[(4'-FLUORO-1,1'-BIPHENYL-4-YL)CARBONYL]-3-NITROBENZENESULFONAMIDE, Serum albumin | | 著者 | Oltersdorf, T, Elmore, S.W, Shoemaker, A.R, Armstrong, R.C, Augeri, D.J, Belli, B.A, Bruncko, M, Deckwerth, T.L, Dinges, J, Hajduk, P.J, Joseph, M.K, Kitada, S, Korsmeyer, S.J, Kunzer, A.R, Letai, A, Li, C, Mitten, M.J, Nettesheim, D.G, Ng, S, Nimmer, P.M, O'Connor, J.M, Oleksijew, A, Petros, A.M, Reed, J.C, Shen, W, Tahir, S.K, Thompson, C.B, Tomaselli, K.J, Wang, B, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H. | | 登録日 | 2005-02-09 | | 公開日 | 2005-06-07 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | An inhibitor of Bcl-2 family proteins induces regression of solid tumours
Nature, 435, 2005
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1W5W
 | | HIV-1 protease in complex with fluoro substituted diol-based C2- symmetric inhibitor | | 分子名称: | (2R,3R,4R,5R)-2,5-BIS[(2,4-DIFLUOROBENZYL)OXY]-3,4-DIHYDROXY-N,N'-BIS[(1R,2S)-2-HYDROXY-2,3-DIHYDRO-1H-INDEN-1-YL]HEXAN EDIAMIDE, POL POLYPROTEIN | | 著者 | Lindberg, J, Pyring, D, Loewgren, S, Rosenquist, A, Zuccarello, G, Kvarnstroem, I, Zhang, H, Vrang, L, Claesson, B, Hallberg, A, Samuelsson, B, Unge, T. | | 登録日 | 2004-08-10 | | 公開日 | 2004-12-22 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Symmetric Fluoro-Substituted Diol-Based HIV Protease Inhibitors. Ortho-Fluorinated and Meta-Fluorinated P1/P1'-Benzyloxy Side Groups Significantly Improve the Antiviral Activity and Preserve Binding Efficacy
Eur.J.Biochem., 271, 2004
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1XA1
 | | Crystal structure of the sensor domain of BlaR1 from Staphylococcus aureus in its apo form | | 分子名称: | PHOSPHATE ION, PYROPHOSPHATE 2-, Regulatory protein blaR1 | | 著者 | Wilke, M.S, Hills, T.L, Zhang, H.Z, Chambers, H.F, Strynadka, N.C. | | 登録日 | 2004-08-24 | | 公開日 | 2004-09-07 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structures of the Apo and penicillin-acylated forms of the BlaR1 beta-lactam sensor of Staphylococcus aureus.
J.Biol.Chem., 279, 2004
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2KEB
 | | NMR solution structure of the N-terminal domain of the DNA polymerase alpha p68 subunit | | 分子名称: | DNA polymerase subunit alpha B | | 著者 | Huang, H, Weiner, B.E, Zhang, H, Fuller, B.E, Gao, Y, Wile, B.M, Chazin, W.J, Fanning, E. | | 登録日 | 2009-01-28 | | 公開日 | 2010-02-02 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of a DNA polymerase alpha-primase domain that docks on the SV40 helicase and activates the viral primosome.
J.Biol.Chem., 285, 2010
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6ZZR
 | | The Crystal Structure of human LDHA from Biortus. | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, L-lactate dehydrogenase A chain | | 著者 | Wang, F, Lin, D, Cheng, W, Bao, X, Zhu, B, Shang, H. | | 登録日 | 2020-08-05 | | 公開日 | 2020-08-19 | | 最終更新日 | 2024-04-24 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | The Crystal Structure of human LDHA from Biortus
To Be Published
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3OJX
 | | Disulfide crosslinked cytochrome P450 reductase inactive | | 分子名称: | FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Xia, C, Hamdane, D, Shen, A, Choi, V, Kasper, C, Zhang, H, Im, S.-C, Waskell, L, Kim, J.-J.P. | | 登録日 | 2010-08-23 | | 公開日 | 2011-02-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Conformational Changes of NADPH-Cytochrome P450 Oxidoreductase Are Essential for Catalysis and Cofactor Binding.
J.Biol.Chem., 286, 2011
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3GZ8
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5YIS
 | | Crystal Structure of AnkB LIR/LC3B complex | | 分子名称: | Ankyrin-2, GLYCEROL, Microtubule-associated proteins 1A/1B light chain 3B, ... | | 著者 | Li, J, Zhu, R, Chen, K, Zheng, H, Yuan, C, Zhang, H, Wang, C, Zhang, M. | | 登録日 | 2017-10-06 | | 公開日 | 2018-05-23 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | | 主引用文献 | Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins.
Nat. Chem. Biol., 14, 2018
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1IM8
 | | Crystal structure of YecO from Haemophilus influenzae (HI0319), a methyltransferase with a bound S-adenosylhomocysteine | | 分子名称: | CHLORIDE ION, S-ADENOSYL-L-HOMOSELENOCYSTEINE, YecO | | 著者 | Lim, K, Zhang, H, Tempczyk, A, Bonander, N, Toedt, J, Howard, A, Eisenstein, E, Herzberg, O, Structure 2 Function Project (S2F) | | 登録日 | 2001-05-10 | | 公開日 | 2001-11-07 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of YecO from Haemophilus influenzae (HI0319) reveals a methyltransferase fold and a bound S-adenosylhomocysteine.
Proteins, 45, 2001
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7V9M
 | | Cryo-EM structure of the GHRH-bound human GHRHR splice variant 1 complex | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | 著者 | Cong, Z.T, Zhou, F.L, Zhang, C, Zou, X.Y, Zhang, H.B, Wang, Y.Z, Zhou, Q.T, Cai, X.Q, Liu, Q.F, Li, J, Shao, L.J, Mao, C.Y, Wang, X, Wu, J.H, Xia, T, Zhao, L.H, Jiang, H.L, Zhang, Y, Xu, H.E, Chen, X, Yang, D.H, Wang, M.W. | | 登録日 | 2021-08-26 | | 公開日 | 2021-10-20 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.29 Å) | | 主引用文献 | Constitutive signal bias mediated by the human GHRHR splice variant 1.
Proc.Natl.Acad.Sci.USA, 118, 2021
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5YIQ
 | | Crystal structure of AnkG LIR/LC3B complex | | 分子名称: | Ankyrin-3, Microtubule-associated proteins 1A/1B light chain 3B, ZINC ION | | 著者 | Li, J, Zhu, R, Chen, K, Zheng, H, Yuan, C, Zhang, H, Wang, C, Zhang, M. | | 登録日 | 2017-10-06 | | 公開日 | 2018-05-23 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins.
Nat. Chem. Biol., 14, 2018
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3GZ6
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