7WV3
 
 | | Toll-like receptor3 linear cluster | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, RNA (80-MER), ... | | Authors: | Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O. | | Deposit date: | 2022-02-09 | | Release date: | 2022-11-16 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (2.26 Å) | | Cite: | TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand.
Nat Commun, 13, 2022
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7WVF
 | | ectoTLR3-mAb12-poly(I:C) complex | | Descriptor: | RNA (46-MER), Toll-like receptor 3, mAb12 | | Authors: | Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O. | | Deposit date: | 2022-02-10 | | Release date: | 2022-11-16 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (3.91 Å) | | Cite: | TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand.
Nat Commun, 13, 2022
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7WVJ
 | | NT-mut(K117D,K139D,K145D) TLR3 -poly I:C complex | | Descriptor: | RNA (46-MER), Toll-like receptor 3 | | Authors: | Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O. | | Deposit date: | 2022-02-10 | | Release date: | 2022-11-16 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.26 Å) | | Cite: | TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand.
Nat Commun, 13, 2022
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7WV5
 | | ectoTLR3-poly(I:C) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, RNA (46-MER), ... | | Authors: | Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O. | | Deposit date: | 2022-02-09 | | Release date: | 2022-11-16 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand.
Nat Commun, 13, 2022
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7WV4
 | | ectoTLR3-poly(I:C) cluster | | Descriptor: | RNA (80-MER), Toll-like receptor 3 | | Authors: | Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O. | | Deposit date: | 2022-02-09 | | Release date: | 2022-11-16 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.35 Å) | | Cite: | TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand.
Nat Commun, 13, 2022
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7WVE
 | | CT-mut (D523K,D524K,E527K) TLR3-poly(I:C) complex | | Descriptor: | RNA (46-MER), Toll-like receptor 3 | | Authors: | Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O. | | Deposit date: | 2022-02-10 | | Release date: | 2022-11-16 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.11 Å) | | Cite: | TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand.
Nat Commun, 13, 2022
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7UJ4
 | | Inhibition of Human Menin by SNDX-5613 | | Descriptor: | 2-({4-[7-({(1r,4r)-4-[(ethanesulfonyl)amino]cyclohexyl}methyl)-2,7-diazaspiro[3.5]nonan-2-yl]pyrimidin-5-yl}oxy)-N-ethyl-5-fluoro-N-(propan-2-yl)benzamide, Isoform 2 of Menin, MAGNESIUM ION | | Authors: | McKeever, B.M, Kulkarni, S, McGeehan, G.M. | | Deposit date: | 2022-03-30 | | Release date: | 2022-12-14 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.96 Å) | | Cite: | MEN1 mutations mediate clinical resistance to menin inhibition.
Nature, 615, 2023
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8E90
 | | Inhibition of Human Menin by SNDX-5613 | | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-({4-[7-({(1r,4r)-4-[(ethanesulfonyl)amino]cyclohexyl}methyl)-2,7-diazaspiro[3.5]nonan-2-yl]pyrimidin-5-yl}oxy)-N-ethyl-5-fluoro-N-(propan-2-yl)benzamide, ... | | Authors: | McKeever, B.M, KULKARNI, S, McGeehan, G.M. | | Deposit date: | 2022-08-26 | | Release date: | 2022-12-14 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | MEN1 mutations mediate clinical resistance to menin inhibition.
Nature, 615, 2023
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1W9N
 | | Isolation and characterization of epilancin 15X, a novel antibiotic from a clinical strain of Staphylococcus epidermidis | | Descriptor: | EPILANCIN 15X | | Authors: | Ekkelenkamp, M, Hanssen, M.G.M, Hsu, S.-T.D, de Jong, A, Milatovic, D, Verhoef, J, van Nuland, N.A.J. | | Deposit date: | 2004-10-14 | | Release date: | 2005-04-01 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Isolation and structural characterization of epilancin 15X, a novel lantibiotic from a clinical strain of Staphylococcus epidermidis.
FEBS Lett., 579, 2005
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