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PDB: 1387 件

1AVF
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BU of 1avf by Molmil
ACTIVATION INTERMEDIATE 2 OF HUMAN GASTRICSIN FROM HUMAN STOMACH
分子名称: GASTRICSIN, SODIUM ION
著者Khan, A.R, Cherney, M.M, Tarasova, N.I, James, M.N.G.
登録日1997-09-16
公開日1998-02-25
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structural characterization of activation 'intermediate 2' on the pathway to human gastricsin.
Nat.Struct.Biol., 4, 1997
4PPN
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BU of 4ppn by Molmil
Mycobacterium tuberculosis RecA citrate bound low temperature structure IIA-BN
分子名称: 1,2-ETHANEDIOL, CITRATE ANION, Protein RecA, ...
著者Chandran, A.V, Prabu, J.R, Patil, N.K, Muniyappa, K, Vijayan, M.
登録日2014-02-27
公開日2015-03-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability
J.Biosci., 40, 2015
4PPF
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BU of 4ppf by Molmil
Mycobacterium tuberculosis RecA citrate bound low temperature structure IIA-N
分子名称: 1,2-ETHANEDIOL, CITRATE ANION, Protein RecA, ...
著者Chandran, A.V, Prabu, J.R, Patil, N.K, Muniyappa, K, Vijayan, M.
登録日2014-02-26
公開日2015-03-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability
J.Biosci., 40, 2015
7K6S
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BU of 7k6s by Molmil
Crystal structure of the bromodomain (BD) of human Bromodomain and PHD finger-containing Transcription Factor (BPTF) bound to Compound 4 (SKT1174)
分子名称: (7-amino-3,4-dihydroquinolin-1(2H)-yl)(cyclopropyl)methanone, 1,2-ETHANEDIOL, CHLORIDE ION, ...
著者Chan, A, Schonbrunn, E.
登録日2020-09-21
公開日2020-12-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.23 Å)
主引用文献New inhibitors for the BPTF bromodomain enabled by structural biology and biophysical assay development.
Org.Biomol.Chem., 18, 2020
6DCM
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BU of 6dcm by Molmil
The atomic resolution crystal structure of Kringle 2 variant bound with EACA
分子名称: 6-AMINOHEXANOIC ACID, Plasminogen
著者Ghanbarpour, A, Geiger, J.
登録日2018-05-07
公開日2019-05-15
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.031 Å)
主引用文献The atomic resolution crystal structure of Kringle 2 variant bound with EACA
To Be Published
4PTL
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BU of 4ptl by Molmil
Mycobacterium tuberculosis RecA glycerol bound low temperature structure IIC-GM
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Protein RecA, ...
著者Chandran, A.V, Prabu, J.R, Patil, N.K, Muniyappa, K, Vijayan, M.
登録日2014-03-11
公開日2015-03-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability
J.Biosci., 40, 2015
7KPR
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BU of 7kpr by Molmil
Structure of wild-type PPM1H phosphatase at 3.1 Angstrom resolution
分子名称: MAGNESIUM ION, Protein phosphatase 1H
著者Khan, A.R, Waschbusch, D.
登録日2020-11-12
公開日2021-08-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Structural basis for the specificity of PPM1H phosphatase for Rab GTPases.
Embo Rep., 22, 2021
7L4J
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BU of 7l4j by Molmil
Crystal structure of WT PPM1H phosphatase
分子名称: MAGNESIUM ION, Protein phosphatase 1H
著者Khan, A.R, Waschbusch, D.
登録日2020-12-19
公開日2021-08-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.451 Å)
主引用文献Structural basis for the specificity of PPM1H phosphatase for Rab GTPases.
Embo Rep., 22, 2021
7L4I
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BU of 7l4i by Molmil
Crystal structure of a substrate-trapping variant of PPM1H phosphatase
分子名称: MAGNESIUM ION, Protein phosphatase 1H
著者Khan, A.R, Waschbusch, D.
登録日2020-12-19
公開日2021-08-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Structural basis for the specificity of PPM1H phosphatase for Rab GTPases.
Embo Rep., 22, 2021
8V9R
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BU of 8v9r by Molmil
Cryo-EM Structure of a Proteolytic ClpXP AAA+ Machine Poised to Unfold a Branched-Degron DHFR-ssrA Substrate Bound with MTX
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ...
著者Ghanbarpour, A, Sauer, R.T, Davis, J.H.
登録日2023-12-09
公開日2024-10-16
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Cryo-EM structure of a fully-engaged DHFR-ssrA substrate and the AAA+ ClpXP protease
To Be Published
4PO9
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BU of 4po9 by Molmil
Mycobacterium tuberculosis RecA glycerol bound low temperature structure IIC-BR
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Protein RecA, ...
著者Chandran, A.V, Prabu, J.R, Patil, N.K, Muniyappa, K, Vijayan, M.
登録日2014-02-25
公開日2015-03-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability
J.Biosci., 40, 2015
4PSV
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BU of 4psv by Molmil
Mycobacterium tuberculosis RecA phosphate bound room temperature structure I-RT
分子名称: PHOSPHATE ION, Protein RecA, 1st part, ...
著者Chandran, A.V, Prabu, J.R, Patil, N.K, Muniyappa, K, Vijayan, M.
登録日2014-03-08
公開日2015-03-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability
J.Biosci., 40, 2015
4PO1
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BU of 4po1 by Molmil
Mycobacterium tuberculosis RecA glycerol bound room temperature structure IIC-RT
分子名称: GLYCEROL, Protein RecA
著者Chandran, A.V, Prabu, J.R, Patil, N.K, Muniyappa, K, Vijayan, M.
登録日2014-02-23
公開日2015-03-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability
J.Biosci., 40, 2015
4POA
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BU of 4poa by Molmil
Mycobacterium tuberculosis RecA glycerol bound low temperature structure IIC-BN
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Protein RecA, ...
著者Chandran, A.V, Prabu, J.R, Patil, N.K, Muniyappa, K, Vijayan, M.
登録日2014-02-25
公開日2015-03-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability
J.Biosci., 40, 2015
2O3M
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BU of 2o3m by Molmil
Monomeric G-DNA tetraplex from human C-kit promoter
分子名称: 5'-D(*AP*GP*GP*GP*AP*GP*GP*GP*CP*GP*CP*TP*GP*GP*GP*AP*GP*GP*AP*GP*GP*G)-3'
著者Phan, A.T, Kuryavyi, V.V, Burge, S, Neidle, S, Patel, D.J.
登録日2006-12-01
公開日2007-05-22
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Structure of an unprecedented G-quadruplex scaffold in the human c-kit promoter.
J.Am.Chem.Soc., 129, 2007
8TEK
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BU of 8tek by Molmil
Baseplate of Nexin-dynein regulatory complex from Tetrahymena thermophila
分子名称: CFAP20, Cilia- and flagella-associated protein 91, Coiled-coil protein, ...
著者Ghanaeian, A.G, Black, C.S, Yang, S.K, Bui, K.H.
登録日2023-07-06
公開日2023-09-20
最終更新日2023-09-27
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Integrated modeling of the Nexin-dynein regulatory complex reveals its regulatory mechanism.
Nat Commun, 14, 2023
8TH8
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BU of 8th8 by Molmil
Linker domain of Nexin-dynein regulatory complex from Tetrahymena thermophila
分子名称: AAA family ATPase CDC48 subfamily protein, Calmodulin 7-2, Coiled-coil domain-containing protein 153, ...
著者Ghanaeian, A.G, Bui, K.H.
登録日2023-07-14
公開日2023-09-20
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (7.4 Å)
主引用文献Integrated modeling of the Nexin-dynein regulatory complex reveals its regulatory mechanism.
Nat Commun, 14, 2023
8TID
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BU of 8tid by Molmil
Combined linker domain of N-DRC and associated proteins Tetrahymena
分子名称: AAA family ATPase CDC48 subfamily protein, CFAP20, Calmodulin 7-2, ...
著者Ghanaeian, A.G, Majhi, S.M, McCaffrey, C.M, Nami, B.N, Black, C.B, Yang, S.K, Legal, T.L, Papoulas, O.P, Janowska, M.J, Valente-Paterno, M.V, Marcotte, E.M, Wloga, D.W, Bui, K.H.
登録日2023-07-19
公開日2023-09-27
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Integrated modeling of the Nexin-dynein regulatory complex reveals its regulatory mechanism.
Nat Commun, 14, 2023
6HH2
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BU of 6hh2 by Molmil
Rab29 small GTPase bound to GDP
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-7L1
著者Khan, A.R, McGrath, E, Waschbusch, D.
登録日2018-08-24
公開日2019-09-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.449 Å)
主引用文献LRRK2 binds to the Rab32 subfamily in a GTP-dependent mannerviaits armadillo domain.
Small GTPases, 2019
4JMQ
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BU of 4jmq by Molmil
Crystal structure of pb9: The Dit of bacteriophage T5.
分子名称: Bacteriophage T5 distal tail protein
著者Flayhan, A, Vellieux, F.M.D, Girard, E, Maury, O, Boulanger, P, Breyton, C.
登録日2013-03-14
公開日2013-11-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.895 Å)
主引用文献Crystal Structure of pb9, the Distal Tail Protein of Bacteriophage T5: a Conserved Structural Motif among All Siphophages.
J.Virol., 88, 2014
7K6R
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BU of 7k6r by Molmil
Crystal structure of the bromodomain (BD) of human Bromodomain and PHD finger-containing Transcription Factor (BPTF) bound to GSK4027
分子名称: 1,2-ETHANEDIOL, 4-bromo-2-methyl-5-[[(3~{R},5~{R})-1-methyl-5-phenyl-piperidin-3-yl]amino]pyridazin-3-one, Nucleosome-remodeling factor subunit BPTF
著者Chan, A, Schonbrunn, E.
登録日2020-09-21
公開日2020-12-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献New inhibitors for the BPTF bromodomain enabled by structural biology and biophysical assay development.
Org.Biomol.Chem., 18, 2020
7KDZ
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BU of 7kdz by Molmil
Crystal structure of the bromodomain (BD) of human Bromodomain and PHD finger-containing Transcription Factor (BPTF) bound to TP-238
分子名称: 1,2-ETHANEDIOL, 6-{4-[3-(dimethylamino)propoxy]phenyl}-2-(methylsulfonyl)-N-[3-(1H-pyrazol-1-yl)propyl]pyrimidin-4-amine, Nucleosome-remodeling factor subunit BPTF
著者Chan, A, Schonbrunn, E.
登録日2020-10-09
公開日2020-12-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献New inhibitors for the BPTF bromodomain enabled by structural biology and biophysical assay development
Organic & Biomolecular Chemistry, 18(27), 2020
7L73
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BU of 7l73 by Molmil
Crystal structure of the first bromodomain (BD1) of human BRDT bound to ERK5-IN-1
分子名称: 11-cyclopentyl-2-({2-ethoxy-4-[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]phenyl}amino)-5-methyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one, Bromodomain testis-specific protein
著者Chan, A, Karim, M.R, Schonbrunn, E.
登録日2020-12-25
公開日2021-06-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Differential BET Bromodomain Inhibition by Dihydropteridinone and Pyrimidodiazepinone Kinase Inhibitors.
J.Med.Chem., 64, 2021
7LEJ
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BU of 7lej by Molmil
Crystal structure of the second bromodomain (BD2) of human BRDT bound to Volasertib
分子名称: Bromodomain testis-specific protein, N-{trans-4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohexyl}-4-{[(7R)-7-ethyl-5-methyl-8-(1-methylethyl)-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzamide
著者Chan, A, Karim, M.R, Schonbrunn, E.
登録日2021-01-14
公開日2021-07-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Differential BET Bromodomain Inhibition by Dihydropteridinone and Pyrimidodiazepinone Kinase Inhibitors.
J.Med.Chem., 64, 2021
7LEL
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BU of 7lel by Molmil
Crystal structure of the second bromodomain (BD2) of human BRDT bound to Bromosporine
分子名称: Bromodomain testis-specific protein, Bromosporine
著者Chan, A, Karim, M.R, Schonbrunn, E.
登録日2021-01-14
公開日2021-07-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Differential BET Bromodomain Inhibition by Dihydropteridinone and Pyrimidodiazepinone Kinase Inhibitors.
J.Med.Chem., 64, 2021

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件を2024-10-30に公開中

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