6F46
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7BGH
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7OFM
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7OFO
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2AKP
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![BU of 2akp by Molmil](/molmil-images/mine/2akp) | Hsp90 Delta24-N210 mutant | 分子名称: | ATP-dependent molecular chaperone HSP82 | 著者 | Richter, K, Moser, S, Hagn, F, Friedrich, R, Hainzl, O, Heller, M, Schlee, S, Kessler, H, Reinstein, J, Buchner, J. | 登録日 | 2005-08-03 | 公開日 | 2006-01-31 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Intrinsic inhibition of the Hsp90 ATPase activity. J.Biol.Chem., 281, 2006
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5JS8
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![BU of 5js8 by Molmil](/molmil-images/mine/5js8) | Structural Model of a Protein alpha subunit in complex with GDP obtained with SAXS and NMR residual couplings | 分子名称: | Guanine nucleotide-binding protein G(i) subunit alpha-1 | 著者 | Goricanec, D, Stehle, R, Grigoriu, S, Wagner, G, Hagn, F. | 登録日 | 2016-05-07 | 公開日 | 2016-06-29 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Conformational dynamics of a G-protein alpha subunit is tightly regulated by nucleotide binding. Proc.Natl.Acad.Sci.USA, 113, 2016
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5JS7
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![BU of 5js7 by Molmil](/molmil-images/mine/5js7) | Structural model of a apo G-protein alpha subunit determined with NMR residual dipolar couplings and SAXS | 分子名称: | Guanine nucleotide-binding protein G(i) subunit alpha-1 | 著者 | Goricanec, D, Stehle, R, Grigoriu, S, Wagner, G, Hagn, F. | 登録日 | 2016-05-07 | 公開日 | 2016-06-29 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Conformational dynamics of a G-protein alpha subunit is tightly regulated by nucleotide binding. Proc.Natl.Acad.Sci.USA, 113, 2016
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3UPV
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![BU of 3upv by Molmil](/molmil-images/mine/3upv) | TPR2B-domain:pHsp70-complex of yeast Sti1 | 分子名称: | Heat shock protein SSA4, Heat shock protein STI1 | 著者 | Schmid, A.B, Lagleder, S, Graewert, M.A, Roehl, A, Hagn, F, Wandinger, S.K, Cox, M.B, Demmer, O, Richter, K, Groll, M, Kessler, H. | 登録日 | 2011-11-18 | 公開日 | 2012-01-25 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The architecture of functional modules in the Hsp90 co-chaperone Sti1/Hop. Embo J., 31, 2012
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3UQ3
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![BU of 3uq3 by Molmil](/molmil-images/mine/3uq3) | TPR2AB-domain:pHSP90-complex of yeast Sti1 | 分子名称: | Heat shock protein, Heat shock protein STI1 | 著者 | Schmid, A.B, Lagleder, S, Graewert, M.A, Roehl, A, Hagn, F, Wandinger, S.K, Cox, M.B, Demmer, O, Richter, K, Groll, M, Kessler, H, Buchner, J. | 登録日 | 2011-11-19 | 公開日 | 2012-01-18 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The architecture of functional modules in the Hsp90 co-chaperone Sti1/Hop. Embo J., 31, 2012
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6Z0I
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![BU of 6z0i by Molmil](/molmil-images/mine/6z0i) | Structure of the TREM2 transmembrane helix in complex with DAP12 in DPC micelles | 分子名称: | Triggering receptor expressed on myeloid cells 2 | 著者 | Steiner, A, Schlepkow, K, Brunner, B, Steiner, H, Haass, C, Hagn, F. | 登録日 | 2020-05-08 | 公開日 | 2020-09-16 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | gamma-Secretase cleavage of the Alzheimer risk factor TREM2 is determined by its intrinsic structural dynamics. Embo J., 2020
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6Z0G
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![BU of 6z0g by Molmil](/molmil-images/mine/6z0g) | Structure of TREM2 transmembrane helix in DPC micelles | 分子名称: | Triggering receptor expressed on myeloid cells 2 | 著者 | Steiner, A, Schlepkow, K, Brunner, B, Steiner, H, Haass, C, Hagn, F. | 登録日 | 2020-05-08 | 公開日 | 2020-09-16 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | gamma-Secretase cleavage of the Alzheimer risk factor TREM2 is determined by its intrinsic structural dynamics. Embo J., 39, 2020
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6Z0H
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![BU of 6z0h by Molmil](/molmil-images/mine/6z0h) | Structure of TREM2 transmembrane helix K186A variant in DPC micelles | 分子名称: | Triggering receptor expressed on myeloid cells 2 | 著者 | Steiner, A, Schlepkow, K, Brunner, B, Steiner, H, Haass, C, Hagn, F. | 登録日 | 2020-05-08 | 公開日 | 2020-09-16 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | gamma-Secretase cleavage of the Alzheimer risk factor TREM2 is determined by its intrinsic structural dynamics. Embo J., 39, 2020
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7L0R
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![BU of 7l0r by Molmil](/molmil-images/mine/7l0r) | Structure of NTS-NTSR1-Gi complex in lipid nanodisc, noncanonical state, without AHD | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Zhang, M, Gui, M, Wang, Z, Gorgulla, C, Yu, J.J, Wu, H, Sun, Z, Klenk, C, Merklinger, L, Morstein, L, Hagn, F, Pluckthun, A, Brown, A, Nasr, M.L, Wagner, G. | 登録日 | 2020-12-12 | 公開日 | 2021-01-06 | 最終更新日 | 2021-03-24 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs. Nat.Struct.Mol.Biol., 28, 2021
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7L0P
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![BU of 7l0p by Molmil](/molmil-images/mine/7l0p) | Structure of NTS-NTSR1-Gi complex in lipid nanodisc, canonical state, without AHD | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Zhang, M, Gui, M, Wang, Z, Gorgulla, C, Yu, J.J, Wu, H, Sun, Z, Klenk, C, Merklinger, L, Morstein, L, Hagn, F, Pluckthun, A, Brown, A, Nasr, M.L, Wagner, G. | 登録日 | 2020-12-12 | 公開日 | 2021-01-06 | 最終更新日 | 2021-03-24 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs. Nat.Struct.Mol.Biol., 28, 2021
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7L0S
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![BU of 7l0s by Molmil](/molmil-images/mine/7l0s) | Structure of NTS-NTSR1-Gi complex in lipid nanodisc, noncanonical state, with AHD | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Zhang, M, Gui, M, Wang, Z, Gorgulla, C, Yu, J.J, Wu, H, Sun, Z, Klenk, C, Merklinger, L, Morstein, L, Hagn, F, Pluckthun, A, Brown, A, Nasr, M.L, Wagner, G. | 登録日 | 2020-12-12 | 公開日 | 2021-01-06 | 最終更新日 | 2021-03-24 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs. Nat.Struct.Mol.Biol., 28, 2021
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7L0Q
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![BU of 7l0q by Molmil](/molmil-images/mine/7l0q) | Structure of NTS-NTSR1-Gi complex in lipid nanodisc, canonical state, with AHD | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Zhang, M, Gui, M, Wang, Z, Gorgulla, C, Yu, J.J, Wu, H, Sun, Z, Klenk, C, Merklinger, L, Morstein, L, Hagn, F, Pluckthun, A, Brown, A, Nasr, M.L, Wagner, G. | 登録日 | 2020-12-12 | 公開日 | 2021-01-06 | 最終更新日 | 2021-03-31 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs. Nat.Struct.Mol.Biol., 28, 2021
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2LLV
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![BU of 2llv by Molmil](/molmil-images/mine/2llv) | Solution structure of the yeast Sti1 DP1 domain | 分子名称: | Heat shock protein STI1 | 著者 | Schmid, A.B, Lagleder, S, Graewert, M.A, Roehl, A, Hagn, F, Wandinger, S.K, Cox, M.B, Demmer, O, Richter, K, Groll, M, Kessler, H, Buchner, J. | 登録日 | 2011-11-17 | 公開日 | 2012-01-25 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | The architecture of functional modules in the Hsp90 co-chaperone Sti1/Hop. Embo J., 31, 2012
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2LLW
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![BU of 2llw by Molmil](/molmil-images/mine/2llw) | Solution structure of the yeast Sti1 DP2 domain | 分子名称: | Heat shock protein STI1 | 著者 | Schmid, A.B, Lagleder, S, Graewert, M.A, Roehl, A, Hagn, F, Wandinger, S.K, Cox, M.B, Demmer, O, Richter, K, Groll, M, Kessler, H, Buchner, J. | 登録日 | 2011-11-17 | 公開日 | 2012-01-25 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | The architecture of functional modules in the Hsp90 co-chaperone Sti1/Hop. Embo J., 31, 2012
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