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PDB: 439 件

2VD1
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Complex structure of prostaglandin D2 synthase at 2.25A.
分子名称: 4-{[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]amino}-2-hydroxybenzoic acid, GLUTATHIONE, GLUTATHIONE-REQUIRING PROSTAGLANDIN D SYNTHASE, ...
著者Hohwy, M, Spadola, L, Lundquist, B, von Wachenfeldt, K, Persdotter, S, Hawtin, P, Dahmen, J, Groth-Clausen, I, Folmer, R.H.A, Edman, K.
登録日2007-09-28
公開日2008-04-15
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Novel Prostaglandin D Synthase Inhibitors Generated by Fragment-Based Drug Design.
J.Med.Chem., 51, 2008
2PZE
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BU of 2pze by Molmil
Minimal human CFTR first nucleotide binding domain as a head-to-tail dimer
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION
著者Atwell, S, Conners, K, Emtage, S, Gheyi, T, Glenn, N.R, Hendle, J, Lewis, H.A, Lu, F, Rodgers, L.A, Romero, R, Sauder, J.M, Smith, D, Tien, H, Wasserman, S.R, Zhao, X.
登録日2007-05-17
公開日2007-10-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structures of a minimal human CFTR first nucleotide-binding domain as a monomer, head-to-tail homodimer, and pathogenic mutant.
Protein Eng.Des.Sel., 23, 2010
1USZ
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SeMet AfaE-3 adhesin from Escherichia Coli
分子名称: AFIMBRIAL ADHESIN AFA-III, CHLORIDE ION, SULFATE ION
著者Anderson, K.L, Billington, J, Pettigrew, D, Cota, E, Roversi, P, Simpson, P, Chen, H.A, Urvil, P, Dumerle, L, Barlow, P, Medof, E, Smith, R.A.G, Nowicki, B, Le Bouguenec, C, Lea, S.M, Matthews, S.
登録日2003-12-02
公開日2004-08-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.28 Å)
主引用文献High Resolution Studies of the Afa/Dr Adhesin Drae and its Interaction with Chloramphenicol
J.Biol.Chem., 279, 2004
2PZF
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Minimal human CFTR first nucleotide binding domain as a head-to-tail dimer with delta F508
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION
著者Atwell, S, Conners, K, Emtage, S, Gheyi, T, Glenn, N.R, Hendle, J, Lewis, H.A, Lu, F, Rodgers, L.A, Romero, R, Sauder, J.M, Smith, D, Tien, H, Wasserman, S.R, Zhao, X.
登録日2007-05-18
公開日2007-10-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of a minimal human CFTR first nucleotide-binding domain as a monomer, head-to-tail homodimer, and pathogenic mutant.
Protein Eng.Des.Sel., 23, 2010
1USQ
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BU of 1usq by Molmil
Complex of E. Coli DraE adhesin with Chloramphenicol
分子名称: 1,2-ETHANEDIOL, CHLORAMPHENICOL, DR HEMAGGLUTININ STRUCTURAL SUBUNIT, ...
著者Anderson, K.L, Billington, J, Pettigrew, D, Cota, E, Roversi, P, Simpson, P, Chen, H.A, Urvil, P, Dumerle, L, Barlow, P, Medof, E, Smith, R.A.G, Nowicki, B, Le Bouguenec, C, Lea, S.M, Matthews, S.
登録日2003-11-27
公開日2004-08-31
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献High Resolution Studies of the Afa/Dr Adhesin Drae and its Interaction with Chloramphenicol
J.Biol.Chem., 279, 2004
1MMC
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BU of 1mmc by Molmil
1H NMR STUDY OF THE SOLUTION STRUCTURE OF AC-AMP2
分子名称: ANTIMICROBIAL PEPTIDE 2
著者Martins, J.C, Maes, D, Loris, R, Pepermans, H.A.M, Wyns, L, Willem, R, Verheyden, P.
登録日1995-10-25
公開日1996-03-08
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献H NMR study of the solution structure of Ac-AMP2, a sugar binding antimicrobial protein isolated from Amaranthus caudatus.
J.Mol.Biol., 258, 1996
1M61
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BU of 1m61 by Molmil
Crystal structure of the apo SH2 domains of ZAP-70
分子名称: PHOSPHATE ION, TYROSINE-PROTEIN KINASE ZAP-70
著者Folmer, R.H.A, Geschwindner, S, Xue, Y.
登録日2002-07-11
公開日2003-07-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure and NMR studies of the apo SH2 domains of ZAP-70: two bikes rather than a tandem
Biochemistry, 41, 2002
2XA8
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BU of 2xa8 by Molmil
Crystal structure of the Fab domain of omalizumab at 2.41A
分子名称: OMALIZUMAB HEAVY CHAIN, OMALIZUMAB LIGHT CHAIN
著者Huang, C.H, Hung, F.H.A, Lim, C, Chang, T.W, Ma, C.
登録日2010-03-30
公開日2011-05-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Structural and Physical Basis for Anti-IgE Therapy.
Sci Rep, 5, 2015
1CJ4
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BU of 1cj4 by Molmil
MUTANT Q34T OF PARA-HYDROXYBENZOATE HYDROXYLASE
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOIC ACID, PROTEIN (P-HYDROXYBENZOATE HYDROXYLASE)
著者Eppink, M.H.M, Overkamp, K.M, Schreuder, H.A, Van Berkel, W.J.H.
登録日1999-04-21
公開日1999-04-30
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Switch of coenzyme specificity of p-hydroxybenzoate hydroxylase.
J.Mol.Biol., 292, 1999
1J6X
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BU of 1j6x by Molmil
CRYSTAL STRUCTURE OF HELICOBACTER PYLORI LUXS
分子名称: AUTOINDUCER-2 PRODUCTION PROTEIN LUXS, METHIONINE, ZINC ION
著者Lewis, H.A, Furlong, E.B, Bergseid, M.G, Sanderson, W.E, Buchanan, S.G.
登録日2001-05-14
公開日2001-06-08
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献A structural genomics approach to the study of quorum sensing: crystal structures of three LuxS orthologs.
Structure, 9, 2001
2PNJ
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BU of 2pnj by Molmil
Crystal structure of human ferrochelatase mutant with Phe 337 replaced by Ala
分子名称: CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ...
著者Dailey, H.A, Wu, C.-K, Horanyi, P, Medlock, A.E, Najahi-Missaoui, W, Burden, A.E, Dailey, T.A, Rose, J.P.
登録日2007-04-24
公開日2007-10-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Altered orientation of active site residues in variants of human ferrochelatase. Evidence for a hydrogen bond network involved in catalysis
Biochemistry, 46, 2007
1ILR
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BU of 1ilr by Molmil
CRYSTAL STRUCTURE OF THE INTERLEUKIN-1 RECEPTOR ANTAGONIST
分子名称: INTERLEUKIN-1 RECEPTOR ANTAGONIST PROTEIN
著者Schreuder, H.A, Rondeau, J.-M, Tardif, C.
登録日1994-06-20
公開日1995-02-07
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Refined crystal structure of the interleukin-1 receptor antagonist. Presence of a disulfide link and a cis-proline.
Eur.J.Biochem., 227, 1995
1IRA
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BU of 1ira by Molmil
COMPLEX OF THE INTERLEUKIN-1 RECEPTOR WITH THE INTERLEUKIN-1 RECEPTOR ANTAGONIST (IL1RA)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, INTERLEUKIN-1 RECEPTOR, INTERLEUKIN-1 RECEPTOR ANTAGONIST
著者Schreuder, H.A, Tardif, C, Tramp-Kalmeyer, S, Soffientini, A, Sarubbi, E, Akeson, A, Bowlin, T, Yanofsky, S, Barrett, R.W.
登録日1998-04-09
公開日1998-06-17
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A new cytokine-receptor binding mode revealed by the crystal structure of the IL-1 receptor with an antagonist.
Nature, 386, 1997
1CJ3
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BU of 1cj3 by Molmil
MUTANT TYR38GLU OF PARA-HYDROXYBENZOATE HYDROXYLASE
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOIC ACID, PROTEIN (P-HYDROXYBENZOATE HYDROXYLASE)
著者Eppink, M.H.M, Overkamp, K.M, Schreuder, H.A, Van Berkel, W.J.H.
登録日1999-04-21
公開日1999-04-30
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Switch of coenzyme specificity of p-hydroxybenzoate hydroxylase.
J.Mol.Biol., 292, 1999
1UT1
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BU of 1ut1 by Molmil
DraE adhesin from Escherichia Coli
分子名称: 1,2-ETHANEDIOL, DR HEMAGGLUTININ STRUCTURAL SUBUNIT, SULFATE ION
著者Anderson, K.L, Billington, J, Pettigrew, D, Cota, E, Roversi, P, Simpson, P, Chen, H.A, Urvil, P, Dumerle, L, Barlow, P, Medof, E, Smith, R.A.G, Nowicki, B, Le Bouguenec, C, Lea, S.M, Matthews, S.
登録日2003-12-02
公開日2004-08-31
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献High Resolution Studies of the Afa/Dr Adhesin Drae and its Interaction with Chloramphenicol
J.Biol.Chem., 279, 2004
1UT2
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AfaE-3 adhesin from Escherichia Coli
分子名称: AFIMBRIAL ADHESIN AFA-III, SULFATE ION
著者Anderson, K.L, Billington, J, Pettigrew, D, Cota, E, Roversi, P, Simpson, P, Chen, H.A, Urvil, P, Dumerle, L, Barlow, P, Medof, E, Smith, R.A.G, Nowicki, B, Le Bouguenec, C, Lea, S.M, Matthews, S.
登録日2003-12-02
公開日2004-08-31
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献High Resolution Studies of the Afa/Dr Adhesin Drae and its Interaction with Chloramphenicol
J.Biol.Chem., 279, 2004
1MJ3
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BU of 1mj3 by Molmil
Crystal Structure Analysis of rat enoyl-CoA hydratase in complex with hexadienoyl-CoA
分子名称: ENOYL-COA HYDRATASE, MITOCHONDRIAL, HEXANOYL-COENZYME A
著者Bell, A.F, Feng, Y, Hofstein, H.A, Parikh, S, Wu, J, Rudolph, M.J, Kisker, C, Tonge, P.J.
登録日2002-08-26
公開日2002-09-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Stereoselectivity of Enoyl-CoA Hydratase Results from Preferential Activation of One of Two Bound Substrate Conformers
Chem.Biol., 9, 2002
2QD3
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Wild type human ferrochelatase crystallized with ammonium sulfate
分子名称: CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ...
著者Medlock, A.E, Dailey, T.A, Ross, T.A, Dailey, H.A, Lanzilotta, W.N.
登録日2007-06-20
公開日2007-10-30
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A pi-Helix Switch Selective for Porphyrin Deprotonation and Product Release in Human Ferrochelatase.
J.Mol.Biol., 373, 2007
2N4S
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BU of 2n4s by Molmil
NMR structure of Fbp28 WW domain L453E mutant
分子名称: Transcription elongation regulator 1
著者Medina, J, Macias, M, Martin-Malpartida, P, Scheraga, H.A.
登録日2015-07-01
公開日2015-10-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Preventing fibril formation of a protein by selective mutation.
Proc.Natl.Acad.Sci.USA, 112, 2015
2N4W
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BU of 2n4w by Molmil
NMR structure of Fbp28 WW domain T456Y mutant
分子名称: Transcription elongation regulator 1
著者Medina, J, Macias, M, Martin-Malpartida, P, Scheraga, H.A.
登録日2015-07-01
公開日2015-10-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Preventing fibril formation of a protein by selective mutation.
Proc.Natl.Acad.Sci.USA, 112, 2015
2QD1
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2.2 Angstrom Structure of the human ferrochelatase variant E343K with substrate bound
分子名称: CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ...
著者Medlock, A.E, Dailey, T.A, Ross, T.A, Dailey, H.A, Lanzilotta, W.N.
登録日2007-06-20
公開日2007-10-30
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A pi-Helix Switch Selective for Porphyrin Deprotonation and Product Release in Human Ferrochelatase.
J.Mol.Biol., 373, 2007
2QD2
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F110A variant of human ferrochelatase with protoheme bound
分子名称: BICARBONATE ION, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ...
著者Medlock, A.E, Dailey, T.A, Ross, T.A, Dailey, H.A, Lanzilota, W.N.
登録日2007-06-20
公開日2007-10-30
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A pi-Helix Switch Selective for Porphyrin Deprotonation and Product Release in Human Ferrochelatase.
J.Mol.Biol., 373, 2007
1VKA
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Southeast Collaboratory for Structural Genomics: Hypothetical Human Protein Q15691 N-Terminal Fragment
分子名称: Microtubule-associated protein RP/EB family member 1
著者Liu, Z.-J, Tempel, W, Schubot, F.D, Shah, A, Dailey, T.A, Mayer, M.R, Rose, J.P, Dailey, H.A, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2004-05-10
公開日2004-07-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Southeast Collaboratory for Structural Genomics: Hypothetical Human Protein Q15691 N-Terminal Fragment
TO BE PUBLISHED
2N4V
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BU of 2n4v by Molmil
NMR structure of Fbp28 WW domain T456D mutant
分子名称: Transcription elongation regulator 1
著者Medina, J, Macias, M, Martin-Malpartida, P, Scheraga, H.A.
登録日2015-07-01
公開日2015-10-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Preventing fibril formation of a protein by selective mutation.
Proc.Natl.Acad.Sci.USA, 112, 2015
2R29
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BU of 2r29 by Molmil
Neutralization of dengue virus by a serotype cross-reactive antibody elucidated by cryoelectron microscopy and x-ray crystallography
分子名称: Envelope protein E, Heavy chain of Fab 1A1D-2, Light chain of Fab 1A1D-2
著者Lok, S.M, Kostyuchenko, V.K, Nybakken, G.E, Holdaway, H.A, Battisti, A.J, Sukupolvi-petty, S, Sedlak, D, Fremont, D.H, Chipman, P.R, Roehrig, J.T, Diamond, M.S, Kuhn, R.J, Rossmann, M.G.
登録日2007-08-24
公開日2007-12-25
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins.
Nat.Struct.Mol.Biol., 15, 2008

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