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PDB: 251 件

7C9N
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Crystal structure of SETDB1 tudor domain in complexed with Compound 1.
分子名称: 3,5-dimethyl-2-[[(3R,5R)-1-methyl-5-phenyl-piperidin-3-yl]amino]pyrrolo[3,2-d]pyrimidin-4-one, Histone-lysine N-methyltransferase SETDB1
著者Guo, Y, Xiong, L, Mao, X, Yang, S.
登録日2020-06-06
公開日2021-04-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.472 Å)
主引用文献Structure-Guided Discovery of a Potent and Selective Cell-Active Inhibitor of SETDB1 Tudor Domain.
Angew.Chem.Int.Ed.Engl., 60, 2021
7CJU
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Crystal structure of inactive form of chitosanase crystallized by ammonium sulfate
分子名称: Glucanase
著者Guo, Y, Qu, L, Nishida, N, Hoshino, T.
登録日2020-07-14
公開日2020-07-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Electrostatic Potentials around the Proteins Preferably Crystallized by Ammonium Sulfate
Cryst.Growth Des., 21, 2021
7XGQ
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Crystal structure of chitosanase crystallized by ammonium sulfate with glycan
分子名称: chitosanase
著者Guo, Y, Hoshino, T.
登録日2022-04-05
公開日2022-04-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Influence of Glycan Agents on Protein Crystallization with Ammonium Sulfate
Cryst.Growth Des., 2022
7XGC
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Crystal structure of influenza polymerase acidic subunit N-terminal domain crystallized by ammonium sulfate with glycan
分子名称: MANGANESE (II) ION, Polymerase acidic protein, SULFATE ION
著者Guo, Y, Hoshino, T.
登録日2022-04-04
公開日2022-04-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Influence of Glycan Agents on Protein Crystallization with Ammonium Sulfate
Cryst.Growth Des., 2022
5XOI
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The structure of OsALKBH1
分子名称: MANGANESE (II) ION, Oxidoreductase, 2OG-Fe oxygenase family protein, ...
著者Wang, C, Guo, Y, Zeng, Z.
登録日2017-05-28
公開日2018-06-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Identification and analysis of adenine N6-methylation sites in the rice genome.
Nat Plants, 4, 2018
8WNT
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Cryo EM map of SLC7A10 with L-Alanine substrate
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ALANINE, ...
著者Li, Y.N, Guo, Y.Y, Dai, L, Yan, R.H.
登録日2023-10-06
公開日2024-05-15
実験手法ELECTRON MICROSCOPY (3.42 Å)
主引用文献Cryo-EM structure of the human Asc-1 transporter complex.
Nat Commun, 15, 2024
8WNS
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Cryo EM map of SLC7A10 in the apo state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Amino acid transporter heavy chain SLC3A2, Asc-type amino acid transporter 1
著者Li, Y.N, Guo, Y.Y, Dai, L, Yan, R.H.
登録日2023-10-06
公開日2024-05-15
実験手法ELECTRON MICROSCOPY (3.42 Å)
主引用文献Cryo-EM structure of the human Asc-1 transporter complex.
Nat Commun, 15, 2024
8WNY
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Cryo EM map of SLC7A10-SLC3A2 complex in the D-serine bound state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Amino acid transporter heavy chain SLC3A2, Asc-type amino acid transporter 1, ...
著者Li, Y.N, Guo, Y.Y, Dai, L, Yan, R.H.
登録日2023-10-06
公開日2024-05-15
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structure of the human Asc-1 transporter complex.
Nat Commun, 15, 2024
3KUF
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The Crystal Structure of the Tudor Domains from FXR1
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Fragile X mental retardation syndrome-related protein 1, GLYCEROL
著者Bian, C, Guo, Y.H, Adams-Cioaba, M.A, Mackenzie, F, Kozieradzki, I, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2009-11-27
公開日2010-01-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of the Tudor domains from Fragile X mental retardation syndrome-related protein 1
To be Published
6LJ9
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Crystal Structure of Se-Met ASFV pS273R protease
分子名称: Cysteine protease S273R
著者Li, G.B, Liu, X.X, Chen, C, Guo, Y.
登録日2019-12-13
公開日2020-02-26
最終更新日2020-05-13
実験手法X-RAY DIFFRACTION (2.307 Å)
主引用文献Crystal Structure of African Swine Fever Virus pS273R Protease and Implications for Inhibitor Design.
J.Virol., 94, 2020
6LJB
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Crystal Structure of ASFV pS273R protease
分子名称: Cysteine protease S273R
著者Li, G.B, Liu, X.X, Chen, C, Guo, Y.
登録日2019-12-13
公開日2020-02-26
最終更新日2020-05-13
実験手法X-RAY DIFFRACTION (2.487 Å)
主引用文献Crystal Structure of African Swine Fever Virus pS273R Protease and Implications for Inhibitor Design.
J.Virol., 94, 2020
6M17
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The 2019-nCoV RBD/ACE2-B0AT1 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Yan, R.H, Zhang, Y.Y, Li, Y.N, Xia, L, Guo, Y.Y, Zhou, Q.
登録日2020-02-24
公開日2020-03-11
最終更新日2021-03-10
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2.
Science, 367, 2020
8HWG
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D5 ATPrS-ADP-ssDNA form
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, ...
著者Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H.
登録日2022-12-29
公開日2024-01-10
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus.
Nat.Struct.Mol.Biol., 31, 2024
8HWH
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Cryo-EM Structure of D5 Apo-ssDNA form
分子名称: DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), Primase D5
著者Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H.
登録日2022-12-29
公開日2024-01-10
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus.
Nat.Struct.Mol.Biol., 31, 2024
8HWD
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Cryo-EM Structure of D5 ADP form
分子名称: ADENOSINE-5'-DIPHOSPHATE, Primase D5
著者Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H.
登録日2022-12-29
公開日2024-01-10
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus.
Nat.Struct.Mol.Biol., 31, 2024
8HWC
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Cryo-EM Structure of D5 Apo
分子名称: Primase D5
著者Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H.
登録日2022-12-29
公開日2024-01-10
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus.
Nat.Struct.Mol.Biol., 31, 2024
8HWF
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Cryo-EM Structure of D5 ADP-ssDNA form
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, ...
著者Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H.
登録日2022-12-29
公開日2024-01-10
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus.
Nat.Struct.Mol.Biol., 31, 2024
8HWB
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D5 ATP-ADP-Apo-ssDNA IS2
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), ...
著者Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H.
登録日2022-12-29
公開日2024-01-10
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus.
Nat.Struct.Mol.Biol., 31, 2024
8HWA
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D5 ATP-ADP-Apo-ssDNA IS1
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), ...
著者Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H.
登録日2022-12-29
公開日2024-01-10
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus.
Nat.Struct.Mol.Biol., 31, 2024
8HWE
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BU of 8hwe by Molmil
Cryo-EM Structure of D5 ATP-ADP form
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Li, Y.N, Zhu, J, Guo, Y.Y, Yan, R.H.
登録日2022-12-29
公開日2024-01-10
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus.
Nat.Struct.Mol.Biol., 31, 2024
8HW5
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Crystal structure of African swine fever virus CP312R
分子名称: ACETIC ACID, CP312R
著者Wang, W.M, Wang, Z.Y, Fu, D, Guo, Y.
登録日2022-12-29
公開日2024-01-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献African swine fever virus CP312R is essential for virus replication and inhibits host protein expression by interacting with RPS27A
To Be Published
8HLC
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S protein of SARS-CoV-2 in complex with 3711
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhang, Y.Y, Guo, Y.Y, Zhou, Q.
登録日2022-11-29
公開日2024-06-05
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献A SARS-CoV-2 Spike N-terminal domain neutralizing antibody targets on a glycans shielded silent face and inhibits virus entry via hindering the recognition of RBD and hACE2
To Be Published
8HLD
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S protein of SARS-CoV-2 in complex with 26434
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Zhang, Y.Y, Guo, Y.Y, Zhou, Q.
登録日2022-11-29
公開日2024-06-05
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献A SARS-CoV-2 Spike N-terminal domain neutralizing antibody targets on a glycans shielded silent face and inhibits virus entry via hindering the recognition of RBD and hACE2
To Be Published
5JIE
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BU of 5jie by Molmil
Crystal structure of the Orsay virus delta protein N-terminal fragment (aa 1~66)
分子名称: Protein delta
著者Fan, Y, Guo, Y, Zhong, W, Tao, Y.J.
登録日2016-04-22
公開日2017-02-22
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.1374 Å)
主引用文献Structure of a pentameric virion-associated fiber with a potential role in Orsay virus entry to host cells.
PLoS Pathog., 13, 2017
5VKQ
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Structure of a mechanotransduction ion channel Drosophila NOMPC in nanodisc
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, No mechanoreceptor potential C isoform L
著者Jin, P, Bulkley, D, Guo, Y, Zhang, W, Guo, Z, Huynh, W, Wu, S, Meltzer, S, Chen, T, Jan, L.Y, Jan, Y.-N, Cheng, Y.
登録日2017-04-22
公開日2017-06-28
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.55 Å)
主引用文献Electron cryo-microscopy structure of the mechanotransduction channel NOMPC.
Nature, 547, 2017

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