4I0P
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![BU of 4i0p by Molmil](/molmil-images/mine/4i0p) | HLA-DO in complex with HLA-DM | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, GLYCEROL, ... | 著者 | Guce, A.I, Mortimer, S.E, Stern, L.J. | 登録日 | 2012-11-18 | 公開日 | 2012-12-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | HLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanism. Nat.Struct.Mol.Biol., 20, 2013
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4NCQ
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![BU of 4ncq by Molmil](/molmil-images/mine/4ncq) | |
3S5Y
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![BU of 3s5y by Molmil](/molmil-images/mine/3s5y) | Pharmacological Chaperoning in Human alpha-Galactosidase | 分子名称: | (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Guce, A.I, Clark, N.E, Garman, S.C. | 登録日 | 2011-05-23 | 公開日 | 2012-01-04 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.105 Å) | 主引用文献 | The molecular basis of pharmacological chaperoning in human alpha-galactosidase Chem.Biol., 18, 2011
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3S5Z
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![BU of 3s5z by Molmil](/molmil-images/mine/3s5z) | Pharmacological Chaperoning in Human alpha-Galactosidase | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, GLYCEROL, ... | 著者 | Guce, A.I, Clark, N.E, Garman, S.C. | 登録日 | 2011-05-23 | 公開日 | 2012-01-04 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | 主引用文献 | The molecular basis of pharmacological chaperoning in human alpha-galactosidase Chem.Biol., 18, 2011
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3HG4
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![BU of 3hg4 by Molmil](/molmil-images/mine/3hg4) | Human alpha-galactosidase catalytic mechanism 3. Covalent intermediate | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Guce, A.I, Clark, N.E, Garman, S.C. | 登録日 | 2009-05-13 | 公開日 | 2009-11-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Catalytic mechanism of human alpha-galactosidase. J.Biol.Chem., 285, 2010
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3HG5
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![BU of 3hg5 by Molmil](/molmil-images/mine/3hg5) | Human alpha-galactosidase catalytic mechanism 4. Product bound | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, Alpha-galactosidase A, ... | 著者 | Guce, A.I, Clark, N.E, Garman, S.C. | 登録日 | 2009-05-13 | 公開日 | 2009-11-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Catalytic mechanism of human alpha-galactosidase. J.Biol.Chem., 285, 2010
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3HG2
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![BU of 3hg2 by Molmil](/molmil-images/mine/3hg2) | Human alpha-galactosidase catalytic mechanism 1. Empty active site | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, Alpha-galactosidase A, ... | 著者 | Guce, A.I, Clark, N.E, Garman, S.C. | 登録日 | 2009-05-13 | 公開日 | 2009-11-24 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Catalytic mechanism of human alpha-galactosidase. J.Biol.Chem., 285, 2010
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3HG3
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![BU of 3hg3 by Molmil](/molmil-images/mine/3hg3) | Human alpha-galactosidase catalytic mechanism 2. Substrate bound | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, ... | 著者 | Guce, A.I, Clark, N.E, Garman, S.C. | 登録日 | 2009-05-13 | 公開日 | 2009-11-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Catalytic mechanism of human alpha-galactosidase. J.Biol.Chem., 285, 2010
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3TV8
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![BU of 3tv8 by Molmil](/molmil-images/mine/3tv8) | Pharmacological Chaperoning in Human alpha-Galactosidase | 分子名称: | (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, ... | 著者 | Rogich, J.J, Guce, A.I, Clark, N.E, Garman, S.C. | 登録日 | 2011-09-19 | 公開日 | 2012-01-04 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.639 Å) | 主引用文献 | The molecular basis of pharmacological chaperoning in human alpha-galactosidase Chem.Biol., 18, 2011
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3LX9
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![BU of 3lx9 by Molmil](/molmil-images/mine/3lx9) | Interconversion of Human Lysosomal Enzyme Specificities | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, ... | 著者 | Tomasic, I.B, Metcalf, M.C, Guce, A.I, Clark, N.E, Garman, S.C. | 登録日 | 2010-02-25 | 公開日 | 2010-05-05 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Interconversion of the specificities of human lysosomal enzymes associated with Fabry and Schindler diseases. J.Biol.Chem., 285, 2010
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3LXA
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![BU of 3lxa by Molmil](/molmil-images/mine/3lxa) | Interconversion of Human Lysosomal Enzyme Specificities | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, ... | 著者 | Tomasic, I.B, Metcalf, M.C, Guce, A.I, Clark, N.E, Garman, S.C. | 登録日 | 2010-02-25 | 公開日 | 2010-05-05 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.04 Å) | 主引用文献 | Interconversion of the specificities of human lysosomal enzymes associated with Fabry and Schindler diseases. J.Biol.Chem., 285, 2010
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3LXC
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![BU of 3lxc by Molmil](/molmil-images/mine/3lxc) | Interconversion of Human Lysosomal Enzyme Specificities | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, GLYCEROL, ... | 著者 | Tomasic, I.B, Metcalf, M.C, Guce, A.I, Clark, N.E, Garman, S.C. | 登録日 | 2010-02-25 | 公開日 | 2010-05-05 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Interconversion of the specificities of human lysosomal enzymes associated with Fabry and Schindler diseases. J.Biol.Chem., 285, 2010
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3LXB
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![BU of 3lxb by Molmil](/molmil-images/mine/3lxb) | Interconversion of Human Lysosomal Enzyme Specificities | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, ... | 著者 | Tomasic, I.B, Metcalf, M.C, Guce, A.I, Clark, N.E, Garman, S.C. | 登録日 | 2010-02-25 | 公開日 | 2010-05-05 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Interconversion of the specificities of human lysosomal enzymes associated with Fabry and Schindler diseases. J.Biol.Chem., 285, 2010
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3G4X
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![BU of 3g4x by Molmil](/molmil-images/mine/3g4x) | Crystal Structure of NiSOD Y9F mutant | 分子名称: | CHLORIDE ION, NICKEL (II) ION, Superoxide dismutase [Ni] | 著者 | Garman, S.C, Guce, A.I, Herbst, R.W, Bryngelson, P.A, Cabelli, D.E, Higgins, K.A, Ryan, K.C, Maroney, M.J. | 登録日 | 2009-02-04 | 公開日 | 2009-04-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Role of conserved tyrosine residues in NiSOD catalysis: a case of convergent evolution Biochemistry, 48, 2009
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3G4Z
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![BU of 3g4z by Molmil](/molmil-images/mine/3g4z) | Crystal Structure of NiSOD Y9F mutant at 1.9 A | 分子名称: | BROMIDE ION, NICKEL (II) ION, Superoxide dismutase [Ni] | 著者 | Garman, S.C, Guce, A.I, Herbst, R.W, Bryngelson, P.A, Cabelli, D.E, Higgins, K.A, Ryan, K.C, Maroney, M.J. | 登録日 | 2009-02-04 | 公開日 | 2009-04-28 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Role of conserved tyrosine residues in NiSOD catalysis: a case of convergent evolution Biochemistry, 48, 2009
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3G50
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![BU of 3g50 by Molmil](/molmil-images/mine/3g50) | Crystal Structure of NiSOD D3A mutant at 1.9 A | 分子名称: | NICKEL (II) ION, Superoxide dismutase [Ni] | 著者 | Garman, S.C, Guce, A.I, Herbst, R.W, Bryngelson, P.A, Cabelli, D.E, Higgins, K.A, Ryan, K.C, Maroney, M.J. | 登録日 | 2009-02-04 | 公開日 | 2009-04-28 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Role of conserved tyrosine residues in NiSOD catalysis: a case of convergent evolution Biochemistry, 48, 2009
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