Loading
PDBj
English日本語简体中文繁體中文한국어
✖
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 69 results
2C1E
DownloadVisualize
BU of 2c1e by Molmil
Crystal structures of caspase-3 in complex with aza-peptide Michael acceptor inhibitors.
Descriptor: AZA-PEPTIDE INHIBITOR (5S, 8R, 11S)-8-(2-CARBOXYETHYL)-5-(CARBOXYMETHYL)-14-(4-ETHOXY-4-OXOBUTANOYL)-11-(1-METHYLETHYL)-3,6,9,12-TETRAOXO-1-PHENYL-2-OXA-4,7,10,13,14-PENTAAZAHEXADECAN -16-OIC ACID, ...
Authors:Grutter, M.G.
Deposit date:2005-09-14
Release date:2006-09-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Design, Synthesis, and Evaluation of Aza-Peptide Michael Acceptors as Selective and Potent Inhibitors of Caspases-2, -3, -6, -7, -8, -9, and - 10.
J.Med.Chem., 49, 2006
3SQB
DownloadVisualize
BU of 3sqb by Molmil
Structure of the major type 1 pilus subunit FimA bound to the FimC chaperone
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Chaperone protein fimC, ...
Authors:Scharer, M.A, Eidam, O, Grutter, M.G, Glockshuber, R, Capitani, G.
Deposit date:2011-07-05
Release date:2012-05-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Quality control of disulfide bond formation in pilus subunits by the chaperone FimC.
Nat.Chem.Biol., 8, 2012
3TJE
DownloadVisualize
BU of 3tje by Molmil
Crystal structure of Fas receptor extracellular domain in complex with Fab E09
Descriptor: 1,2-ETHANEDIOL, CADMIUM ION, CHLORIDE ION, ...
Authors:Zuger, S, Stirnimann, C, Briand, C, Grutter, M.G.
Deposit date:2011-08-24
Release date:2012-05-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:A series of Fas receptor agonist antibodies that demonstrate an inverse correlation between affinity and potency.
Cell Death Differ., 19, 2012
1F9E
DownloadVisualize
BU of 1f9e by Molmil
CASPASE-8 SPECIFICITY PROBED AT SUBSITE S4: CRYSTAL STRUCTURE OF THE CASPASE-8-Z-DEVD-CHO
Descriptor: (PHQ)DEVD, CASPASE-8 ALPHA CHAIN, CASPASE-8 BETA CHAIN
Authors:Blanchard, H, Donepudi, M, Tschopp, M, Kodandapani, L, Wu, J.C, Grutter, M.G.
Deposit date:2000-07-10
Release date:2001-07-10
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Caspase-8 specificity probed at subsite S(4): crystal structure of the caspase-8-Z-DEVD-cho complex.
J.Mol.Biol., 302, 2000
3THM
DownloadVisualize
BU of 3thm by Molmil
Crystal structure of Fas receptor extracellular domain in complex with Fab EP6b_B01
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Fab EP6b_B01, ...
Authors:Zuger, S, Stirnimann, C, Briand, C, Grutter, M.G.
Deposit date:2011-08-19
Release date:2012-05-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A series of Fas receptor agonist antibodies that demonstrate an inverse correlation between affinity and potency.
Cell Death Differ., 19, 2012
2V12
DownloadVisualize
BU of 2v12 by Molmil
Crystal Structure of Renin with Inhibitor 8
Descriptor: N-[(2S,4S,5S,7R)-4-AMINO-8-(BUTYLAMINO)-5-HYDROXY-7-METHYL-2-(1-METHYLETHYL)-8-OXOOCTYL]-2-(3-METHOXYPROPOXY)BENZAMIDE, RENIN
Authors:Rahuel, J, Rasetti, V, Maibaum, J, Rueger, H, Goschke, R, Cohen, N.C, Stutz, S, Cumin, F, Fuhrer, W, Wood, J.M, Grutter, M.G.
Deposit date:2007-05-21
Release date:2007-07-03
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure-Based Drug Design: The Discovery of Novel Nonpeptide Orally Active Inhibitors of Human Renin
Chem.Biol., 7, 2000
3C7M
DownloadVisualize
BU of 3c7m by Molmil
Crystal structure of reduced DsbL
Descriptor: CADMIUM ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Stirnimann, C.U, Grimshaw, J.P.A, Glockshuber, R, Grutter, M.G, Capitani, G.
Deposit date:2008-02-07
Release date:2008-07-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:DsbL and DsbI form a specific dithiol oxidase system for periplasmic arylsulfate sulfotransferase in uropathogenic Escherichia coli.
J.Mol.Biol., 380, 2008
2V16
DownloadVisualize
BU of 2v16 by Molmil
Crystal Structure of Renin with Inhibitor 3
Descriptor: METHYL (3R)-1-[(5S,6S,8R)-5-AMINO-9-BUTYLAMINO-6-HYDROXY-3,3,8-TRIMETHYL-9-OXO-NONANOYL]-3,4-DIHYDRO-2H-QUINOLINE-3-CARBOXYLATE, RENIN
Authors:Rahuel, J, Rasetti, V, Maibaum, J, Rueger, H, Goschke, R, Cohen, N.C, Stutz, S, Cumin, F, Fuhrer, W, Wood, J.M, Grutter, M.G.
Deposit date:2007-05-22
Release date:2008-07-08
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-Based Drug Design: The Discovery of Novel Nonpeptide Orally Active Inhibitors of Human Renin
Chem.Biol., 7, 2000
2V0Z
DownloadVisualize
BU of 2v0z by Molmil
Crystal Structure of Renin with Inhibitor 10 (Aliskiren)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ALISKIREN, RENIN
Authors:Rahuel, J, Rasetti, V, Maibaum, J, Rueger, H, Goschke, R, Cohen, N.C, Stutz, S, Cumin, F, Fuhrer, W, Wood, J.M, Grutter, M.G.
Deposit date:2007-05-21
Release date:2007-07-03
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure-Based Drug Design: The Discovery of Novel Nonpeptide Orally Active Inhibitors of Human Renin
Chem.Biol., 7, 2000
2V13
DownloadVisualize
BU of 2v13 by Molmil
Crystal Structure of Renin with Inhibitor 7
Descriptor: N-[(2R,4S,5S,7R)-4-AMINO-8-(BUTYLAMINO)-5-HYDROXY-2,7-DIMETHYL-8-OXOOCTYL]-2-(3-METHOXYPROPOXY)BENZAMIDE, RENIN
Authors:Rahuel, J, Rasetti, V, Maibaum, J, Rueger, H, Goschke, R, Cohen, N.C, Stutz, S, Cumin, F, Fuhrer, W, Wood, J.M, Grutter, M.G.
Deposit date:2007-05-21
Release date:2008-07-08
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-Based Drug Design: The Discovery of Novel Nonpeptide Orally Active Inhibitors of Human Renin
Chem.Biol., 7, 2000
2V11
DownloadVisualize
BU of 2v11 by Molmil
Crystal Structure of Renin with Inhibitor 6
Descriptor: (2S,4S,5R,7R)-4-AMINO-8-(BUTYLAMINO)-5-HYDROXY-2,7-DIMETHYL-8-OXOOCTYL 1-BENZYL-1H-INDOLE-3-CARBOXYLATE, RENIN
Authors:Rahuel, J, Rasetti, V, Maibaum, J, Rueger, H, Goschke, R, Cohen, N.C, Stutz, S, Cumin, F, Fuhrer, W, Wood, J.M, Grutter, M.G.
Deposit date:2007-05-21
Release date:2007-07-03
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure-Based Drug Design: The Discovery of Novel Nonpeptide Orally Active Inhibitors of Human Renin
Chem.Biol., 7, 2000
2V10
DownloadVisualize
BU of 2v10 by Molmil
Crystal Structure of Renin with Inhibitor 9
Descriptor: (2R,4S,5S,7S)-5-AMINO-N-BUTYL-4-HYDROXY-7-[4-METHOXY-3-(3-METHOXYPROPOXY)BENZYL]-2,8-DIMETHYLNONANAMIDE, RENIN
Authors:Rahuel, J, Rasetti, V, Maibaum, J, Rueger, H, Goschke, R, Cohen, N.C, Stutz, S, Cumin, F, Fuhrer, W, Wood, J.M, Grutter, M.G.
Deposit date:2007-05-21
Release date:2007-07-03
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure-Based Drug Design: The Discovery of Novel Nonpeptide Orally Active Inhibitors of Human Renin
Chem.Biol., 7, 2000
3BWU
DownloadVisualize
BU of 3bwu by Molmil
Crystal structure of the ternary complex of FimD (N-Terminal Domain, FimDN) with FimC and the N-terminally truncated pilus subunit FimF (FimFt)
Descriptor: 1,2-ETHANEDIOL, Chaperone protein fimC, DI(HYDROXYETHYL)ETHER, ...
Authors:Eidam, O, Grutter, M.G, Capitani, G.
Deposit date:2008-01-10
Release date:2008-03-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Crystal structure of the ternary FimC-FimF(t)-FimD(N) complex indicates conserved pilus chaperone-subunit complex recognition by the usher FimD
Febs Lett., 582, 2008
1TZE
DownloadVisualize
BU of 1tze by Molmil
SIGNAL TRANSDUCTION ADAPTOR GROWTH FACTOR, GRB2 SH2 DOMAIN COMPLEXED WITH PHOSPHOTYROSYL HEPTAPEPTIDE LYS-PRO-PHE-PTYR-VAL-ASN-VAL-NH2 (KFPPYVNC-NH2)
Descriptor: GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2, PHOSPHOTYROSYL HEPTAPEPTIDE LYS-PRO-PHE-PTYR-VAL-ASN-VAL-NH2
Authors:Rahuel, J, Grutter, M.G.
Deposit date:1996-06-06
Release date:1997-07-07
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for specificity of Grb2-SH2 revealed by a novel ligand binding mode.
Nat.Struct.Biol., 3, 1996
3BFW
DownloadVisualize
BU of 3bfw by Molmil
Crystal structure of truncated FimG (FimGt) in complex with the donor strand peptide of FimF (DSF)
Descriptor: Protein fimF, Protein fimG, YTTRIUM (III) ION
Authors:Eidam, O, Capitani, G, Grutter, M.G.
Deposit date:2007-11-23
Release date:2008-03-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Infinite Kinetic Stability against Dissociation of Supramolecular Protein Complexes through Donor Strand Complementation
Structure, 16, 2008
3BFQ
DownloadVisualize
BU of 3bfq by Molmil
Crystal structure of truncated FimG (FimGt) in complex with the donor strand peptide of FimF (DSF)
Descriptor: COBALT (II) ION, Protein fimF, Protein fimG
Authors:Eidam, O, Capitani, G, Grutter, M.G.
Deposit date:2007-11-23
Release date:2008-03-04
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Infinite Kinetic Stability against Dissociation of Supramolecular Protein Complexes through Donor Strand Complementation
Structure, 16, 2008
2XEH
DownloadVisualize
BU of 2xeh by Molmil
Structural Determinants for Improved Thermal Stability of Designed Ankyrin Repeat Proteins With a Redesigned C-capping Module.
Descriptor: NI3C MUT6, SULFATE ION
Authors:Kramer, M, Wetzel, S.K, Pluckthun, A, Mittl, P, Grutter, M.
Deposit date:2010-05-14
Release date:2010-08-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Structural Determinants for Improved Thermal Stability of Designed Ankyrin Repeat Proteins with a Redesigned C-Capping Module.
J.Mol.Biol., 404, 2010
3MAU
DownloadVisualize
BU of 3mau by Molmil
Crystal structure of StSPL in complex with phosphoethanolamine
Descriptor: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, PHOSPHATE ION, sphingosine-1-phosphate lyase, ...
Authors:Bourquin, F, Grutter, M.G, Capitani, G.
Deposit date:2010-03-24
Release date:2010-08-18
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure and Function of Sphingosine-1-Phosphate Lyase, a Key Enzyme of Sphingolipid Metabolism.
Structure, 18, 2010
3PIU
DownloadVisualize
BU of 3piu by Molmil
High-resolution structure of native Malus domestica ACC synthase
Descriptor: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, 1-aminocyclopropane-1-carboxylate synthase
Authors:Scharer, M.A, Grutter, M.G, Capitani, G.
Deposit date:2010-11-08
Release date:2010-12-15
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural basis for reduced activity of 1-aminocyclopropane-1-carboxylate synthase affected by a mutation linked to andromonoecy.
Febs Lett., 585, 2011
2XEN
DownloadVisualize
BU of 2xen by Molmil
Structural Determinants for Improved Thermal Stability of Designed Ankyrin Repeat Proteins With a Redesigned C-capping Module.
Descriptor: 1,2-ETHANEDIOL, METHANOL, NI1C MUT4, ...
Authors:Kramer, M, Wetzel, S.K, Pluckthun, A, Mittl, P, Grutter, M.
Deposit date:2010-05-17
Release date:2010-08-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Determinants for Improved Thermal Stability of Designed Ankyrin Repeat Proteins with a Redesigned C-Capping Module.
J.Mol.Biol., 404, 2010
1PMM
DownloadVisualize
BU of 1pmm by Molmil
Crystal structure of Escherichia coli GadB (low pH)
Descriptor: ACETIC ACID, Glutamate decarboxylase beta, PYRIDOXAL-5'-PHOSPHATE
Authors:Capitani, G, De Biase, D, Aurizi, C, Gut, H, Bossa, F, Grutter, M.G.
Deposit date:2003-06-11
Release date:2004-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure and functional analysis of escherichia coli glutamate decarboxylase
Embo J., 22, 2003
2XEE
DownloadVisualize
BU of 2xee by Molmil
Structural Determinants for Improved Thermal Stability of Designed Ankyrin Repeat Proteins With a Redesigned C-capping Module.
Descriptor: NI3C DARPIN MUTANT5
Authors:Kramer, M, Wetzel, S.K, Pluckthun, A, Mittl, P, Grutter, M.
Deposit date:2010-05-14
Release date:2010-08-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Determinants for Improved Thermal Stability of Designed Ankyrin Repeat Proteins with a Redesigned C-Capping Module.
J.Mol.Biol., 404, 2010
1PMO
DownloadVisualize
BU of 1pmo by Molmil
Crystal structure of Escherichia coli GadB (neutral pH)
Descriptor: (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Glutamate decarboxylase beta
Authors:Capitani, G, De Biase, D, Aurizi, C, Gut, H, Bossa, F, Grutter, M.G.
Deposit date:2003-06-11
Release date:2004-02-17
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure and functional analysis of escherichia coli glutamate decarboxylase
Embo J., 22, 2003
1QDU
DownloadVisualize
BU of 1qdu by Molmil
CRYSTAL STRUCTURE OF THE COMPLEX OF CASPASE-8 WITH THE TRIPEPTIDE KETONE INHIBITOR ZEVD-DCBMK
Descriptor: CASPASE-8 ALPHA-CHAIN, CASPASE-8 BETA-CHAIN, PHQ-GLU-VAL-ASP-DICHLOROMETHYLKETONE INHIBITOR
Authors:Blanchard, H, Grutter, M.G.
Deposit date:1999-07-10
Release date:2000-07-10
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The three-dimensional structure of caspase-8: an initiator enzyme in apoptosis.
Structure Fold.Des., 7, 1999
1J0X
DownloadVisualize
BU of 1j0x by Molmil
Crystal structure of the rabbit muscle glyceraldehyde-3-phosphate dehydrogenase (GAPDH)
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, glyceraldehyde-3-phosphate dehydrogenase
Authors:Cowan-Jacob, S.W, Kaufmann, M, Anselmo, A.N, Stark, W, Grutter, M.G.
Deposit date:2002-11-25
Release date:2003-12-09
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of rabbit-muscle glyceraldehyde-3-phosphate dehydrogenase.
Acta Crystallogr.,Sect.D, 59, 2003

 

123>

218853

PDB entries from 2024-04-24

PDB statisticsPDBj update infoContact PDBjnumon