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PDB: 96 件

4LUN
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Structure of the N-terminal mIF4G domain from S. cerevisiae Upf2, a protein involved in the degradation of mRNAs containing premature stop codons
分子名称: CHLORIDE ION, Nonsense-mediated mRNA decay protein 2
著者Fourati, Z, Roy, B, Millan, C, Courreux, P.D, Kervestin, S, van Tilbeurgh, H, He, F, Uson, I, Jacobson, A, Graille, M.
登録日2013-07-25
公開日2014-07-30
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.641 Å)
主引用文献A highly conserved region essential for NMD in the Upf2 N-terminal domain.
J.Mol.Biol., 426, 2014
4XAH
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X-ray crystal structure of S. cerevisiae Cgi121
分子名称: EKC/KEOPS complex subunit CGI121
著者Zhang, W, Graille, M, Collinet, B, van Tilbeurgh, H.
登録日2014-12-14
公開日2015-03-18
最終更新日2015-04-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of the Gon7/Pcc1 and Bud32/Cgi121 complexes provide a model for the complete yeast KEOPS complex.
Nucleic Acids Res., 43, 2015
3MGU
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Structure of S. cerevisiae Tpa1 protein, a proline hydroxylase modifying ribosomal protein Rps23
分子名称: FE (II) ION, PKHD-type hydroxylase TPA1
著者Henri, J, Rispal, D, Bayart, E, van Tilbeurgh, H, Seraphin, B, Graille, M.
登録日2010-04-07
公開日2010-07-14
最終更新日2018-01-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural and functional insights into S. cerevisiae Tpa1, a putative prolyl hydroxylase influencing translation termination and transcription
To be Published
3P27
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Crystal structure of S. cerevisiae Hbs1 protein (GDP-bound form), a translational GTPase involved in RNA quality control pathways and interacting with Dom34/Pelota
分子名称: Elongation factor 1 alpha-like protein, GUANOSINE-5'-DIPHOSPHATE
著者van den Elzen, A, Henri, J, Lazar, N, Gas, M.E, Durand, D, Lacroute, F, Nicaise, M, van Tilbeurgh, H, Sraphin, B, Graille, M, Paris-Sud Yeast Structural Genomics (YSG)
登録日2010-10-01
公開日2010-11-17
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Dissection of Dom34-Hbs1 reveals independent functions in two RNA quality control pathways.
Nat.Struct.Mol.Biol., 17, 2010
6H2V
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Crystal structure of human METTL5-TRMT112 complex, the 18S rRNA m6A1832 methyltransferase at 2.5A resolution
分子名称: 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, DI(HYDROXYETHYL)ETHER, ...
著者van Tran, N, Graille, M.
登録日2018-07-16
公開日2019-07-31
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献The human 18S rRNA m6A methyltransferase METTL5 is stabilized by TRMT112.
Nucleic Acids Res., 47, 2019
6H57
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Crystal structure of S. cerevisiae DEAH-box RNA helicase Dhr1, essential for small ribosomal subunit biogenesis
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ...
著者Roychowdhury, A, Graille, M.
登録日2018-07-24
公開日2019-06-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The DEAH-box RNA helicase Dhr1 contains a remarkable carboxyl terminal domain essential for small ribosomal subunit biogenesis.
Nucleic Acids Res., 47, 2019
6H2U
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Crystal structure of human METTL5-TRMT112 complex, the 18S rRNA m6A1832 methyltransferase at 1.6A resolution
分子名称: 1,2-ETHANEDIOL, Methyltransferase-like protein 5, Multifunctional methyltransferase subunit TRM112-like protein, ...
著者van Tran, N, Graille, M.
登録日2018-07-16
公開日2019-07-31
最終更新日2019-09-18
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The human 18S rRNA m6A methyltransferase METTL5 is stabilized by TRMT112.
Nucleic Acids Res., 47, 2019
3P26
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Crystal structure of S. cerevisiae Hbs1 protein (apo-form), a translational GTPase involved in RNA quality control pathways and interacting with Dom34/Pelota
分子名称: Elongation factor 1 alpha-like protein
著者van den Elzen, A, Henri, J, Lazar, N, Gas, M.E, Durand, D, Lacroute, F, Nicaise, M, van Tilbeurgh, H, Sraphin, B, Graille, M, Paris-Sud Yeast Structural Genomics (YSG)
登録日2010-10-01
公開日2010-11-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Dissection of Dom34-Hbs1 reveals independent functions in two RNA quality control pathways.
Nat.Struct.Mol.Biol., 17, 2010
2IVO
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Structure of UP1 protein
分子名称: TUNGSTATE(VI)ION, UP1
著者Hecker, A, Leulliot, N, Graille, M, Dorlet, P, Quevillon-Cheruel, S, Ulryck, N, Van Tilbeurgh, H, Forterre, P.
登録日2006-06-14
公開日2007-07-31
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献An Archaeal Orthologue of the Universal Protein Kae1 is an Iron Metalloprotein which Exhibits Atypical DNA-Binding Properties and Apurinic-Endonuclease Activity in Vitro.
Nucleic Acids Res., 35, 2007
2IVN
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Structure of UP1 protein
分子名称: GLYCEROL, MAGNESIUM ION, O-SIALOGLYCOPROTEIN ENDOPEPTIDASE, ...
著者Hecker, A, Leulliot, N, Graille, M, Dorlet, P, Quevillon-Cheruel, S, Ulryck, N, Van Tilbeurgh, H, Forterre, P.
登録日2006-06-14
公開日2007-07-31
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献An Archaeal Orthologue of the Universal Protein Kae1 is an Iron Metalloprotein which Exhibits Atypical DNA-Binding Properties and Apurinic-Endonuclease Activity in Vitro.
Nucleic Acids Res., 35, 2007
2J6A
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Structure of S. cerevisiae Trm112 protein, a methyltransferase activator
分子名称: 1,2-ETHANEDIOL, PROTEIN TRM112, ZINC ION
著者Heurgue-Hamard, V, Graille, M, Scrima, N, Ulryck, N, Champ, S, Van Tilbeurgh, H, Buckingham, R.H.
登録日2006-09-27
公開日2006-09-28
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Zinc Finger Protein Ynr046W is Plurifunctional and a Component of the Erf1 Methyltransferase in Yeast.
J.Biol.Chem., 281, 2006
4G75
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Structure of PaeM, a colicin M-like bacteriocin produced by Pseudomonas aeruginosa
分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, phosphodiesterase
著者Touze, T, Graille, M, Mengin-Lecreulx, D.
登録日2012-07-20
公開日2012-09-12
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Functional and Structural Characterization of PaeM, a Colicin M-like Bacteriocin Produced by Pseudomonas aeruginosa.
J.Biol.Chem., 287, 2012
2IVP
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Structure of UP1 protein
分子名称: ADENOSINE-5'-TRIPHOSPHATE, FE (II) ION, O-SIALOGLYCOPROTEIN ENDOPEPTIDASE
著者Hecker, A, Leulliot, N, Graille, M, Dorlet, P, Quevillon-Cheruel, S, Ulryck, N, Van Tilbeurgh, H, Forterre, P.
登録日2006-06-14
公開日2007-07-31
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献An Archaeal Orthologue of the Universal Protein Kae1 is an Iron Metalloprotein which Exhibits Atypical DNA-Binding Properties and Apurinic-Endonuclease Activity in Vitro.
Nucleic Acids Res., 35, 2007
4G76
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Structure of PaeM, a colicin M-like bacteriocin produced by Pseudomonas aeruginosa
分子名称: Phosphodiesterase
著者Touze, T, Graille, M, Mengin-Lecreulx, D.
登録日2012-07-20
公開日2012-09-12
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.385 Å)
主引用文献Functional and Structural Characterization of PaeM, a Colicin M-like Bacteriocin Produced by Pseudomonas aeruginosa.
J.Biol.Chem., 287, 2012
1OCU
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BU of 1ocu by Molmil
Crystal structure of the yeast PX-domain protein Grd19p (sorting nexin 3) complexed to phosphatidylinosytol-3-phosphate.
分子名称: 2-(BUTANOYLOXY)-1-{[(HYDROXY{[2,3,4,6-TETRAHYDROXY-5-(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTANOATE, SORTING NEXIN
著者Zhou, C.Z, Li de La Sierra-Gallay, I, Cheruel, S, Collinet, B, Minard, P, Blondeau, K, Henkes, G, Aufrere, R, Leulliot, N, Graille, M, Sorel, I, Savarin, P, de la Torre, F, Poupon, A, Janin, J, van Tilbeurgh, H.
登録日2003-02-10
公開日2003-12-12
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the yeast Phox homology (PX) domain protein Grd19p complexed to phosphatidylinositol-3-phosphate.
J. Biol. Chem., 278, 2003
1OCS
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Crystal structure of the yeast PX-doamin protein Grd19p (sorting nexin3) complexed to phosphatidylinosytol-3-phosphate.
分子名称: GLYCEROL, SORTING NEXIN GRD19
著者Zhou, C.Z, Li De La Sierra-Gallay, I, Cheruel, S, Collinet, B, Minard, P, Blondeau, K, Henkes, G, Aufrere, R, Leulliot, N, Graille, M, Sorel, I, Savarin, P, De La Torre, F, Poupon, A, Janin, J, Van Tilbeurgh, H.
登録日2003-02-10
公開日2003-12-12
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Crystal Structure of the Yeast Phox Homology (Px) Protein Grd19P (Sorting Nexin 3) Complexed to Phosphatidylinositol-3-Phosphate
J.Biol.Chem., 278, 2003
3QTM
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Structure of S. pombe nuclear import adaptor Nro1 (Space group P21)
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, SULFATE ION, ...
著者Rispal, D, Henri, J, van Tilbeurgh, H, Graille, M, Seraphin, B.
登録日2011-02-23
公開日2011-09-21
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural and functional analysis of Nro1/Ett1: a protein involved in translation termination in S. cerevisiae and in O2-mediated gene control in S. pombe
Rna, 17, 2011
3QTN
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Structure of S. pombe nuclear import adaptor Nro1 (Space group P6522)
分子名称: Uncharacterized protein C4B3.07
著者Rispal, D, Henri, J, van Tilbeurgh, H, Graille, M, Seraphin, B.
登録日2011-02-23
公開日2011-09-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.499 Å)
主引用文献Structural and functional analysis of Nro1/Ett1: a protein involved in translation termination in S. cerevisiae and in O2-mediated gene control in S. pombe
Rna, 17, 2011
3Q87
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Structure of E. cuniculi Mtq2-Trm112 complex responible for the methylation of eRF1 translation termination factor
分子名称: N6 adenine specific DNA methylase, Putative uncharacterized protein ECU08_1170, S-ADENOSYLMETHIONINE, ...
著者Liger, D, Mora, L, Lazar, N, Figaro, S, Henri, J, Scrima, N, Buckingham, R.H, van Tilbeurgh, H, Heurgue-Hamard, V, Graille, M.
登録日2011-01-06
公開日2011-05-18
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.997 Å)
主引用文献Mechanism of activation of methyltransferases involved in translation by the Trm112 'hub' protein
Nucleic Acids Res., 2011
1XE7
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Crystal structure of the YML079w protein from Saccharomyces cerevisiae reveals a new sequence family of the jelly roll fold
分子名称: 1,2-ETHANEDIOL, ACETIC ACID, GUANINE, ...
著者Zhou, C.-Z, Meyer, P, Quevillon-Cheruel, S, Li de La Sierra-Gallay, I, Collinet, B, Graille, M, Leulliot, N, Sorel, I, Janin, J, Van Tilbeurgh, H.
登録日2004-09-09
公開日2005-01-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structure of the YML079w protein from Saccharomyces cerevisiae reveals a new sequence family of the jelly-roll fold
Protein Sci., 14, 2005
1XE8
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Crystal structure of the YML079w protein from Saccharomyces cerevisiae reveals a new sequence family of the jelly roll fold.
分子名称: ADENINE, CITRIC ACID, GLYCEROL, ...
著者Zhou, C.-Z, Meyer, P, Quevillon-Cheruel, S, Li de La Sierra-Gallay, I, Collinet, B, Graille, M, Leulliot, N, Sorel, I, Janin, J, Van Tilbeurgh, H.
登録日2004-09-09
公開日2005-01-11
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the YML079w protein from Saccharomyces cerevisiae reveals a new sequence family of the jelly-roll fold
Protein Sci., 14, 2005
1YCD
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Crystal structure of yeast FSH1/YHR049W, a member of the serine hydrolase family
分子名称: 2-HYDROXY-4,5-DIOXOHEPTYL HYDROGEN PHOSPHONATE, Hypothetical 27.3 kDa protein in AAP1-SMF2 intergenic region
著者Leulliot, N, Graille, M, Coste, F, Quevillon-Cheruel, S, Janin, J, van Tilbeurgh, H, Paris-Sud Yeast Structural Genomics (YSG)
登録日2004-12-22
公開日2005-05-10
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of yeast YHR049W/FSH1, a member of the serine hydrolase family.
Protein Sci., 14, 2005
4FZB
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Structure of thymidylate synthase ThyX complexed to a new inhibitor
分子名称: 2-hydroxy-3-(4-methoxybenzyl)naphthalene-1,4-dione, DIMETHYL SULFOXIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Basta, T, Boum, Y, Briffotaux, J, Becker, H.F, Lamarre-Jouenne, I, Lambry, J.C, Skouloubris, S, Liebl, U, van Tilbeurgh, H, Graille, M, Myllylkallio, H.
登録日2012-07-06
公開日2013-05-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Mechanistic and structural basis for inhibition of thymidylate synthase ThyX.
Open Biology, 2, 2012
2V3J
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The yeast ribosome synthesis factor Emg1 alpha beta knot fold methyltransferase
分子名称: ESSENTIAL FOR MITOTIC GROWTH 1, SULFATE ION
著者Leulliot, N, Bohnsack, M.T, Graille, M, Tollervey, D, Van Tilbeurgh, H.
登録日2007-06-18
公開日2007-12-04
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Yeast Ribosome Synthesis Factor Emg1 is a Novel Member of the Superfamily of Alpha/Beta Knot Fold Methyltransferases.
Nucleic Acids Res., 36, 2008
2VWB
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Structure of the archaeal Kae1-Bud32 fusion protein MJ1130: a model for the eukaryotic EKC-KEOPS subcomplex involved in transcription and telomere homeostasis.
分子名称: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PUTATIVE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE
著者Hecker, A, Lopreiato, R, Graille, M, Collinet, B, Forterre, P, Domenico, L, van Tilbeurgh, H.
登録日2008-06-20
公開日2008-08-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structure of the Archaeal Kae1/Bud32 Fusion Protein Mj1130: A Model for the Eukaryotic Ekc/Keops Subcomplex
Embo J., 27, 2008

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