5LMF
 
 | | Structure of C-terminal domain from S. cerevisiae Pat1 decapping activator bound to Dcp2 HLM3 peptide (region 484-500) | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DNA topoisomerase 2-associated protein PAT1, ... | | Authors: | Charenton, C, Gaudon-Plesse, C, Fourati, Z, Taverniti, V, Back, R, Kolesnikova, O, Seraphin, B, Graille, M. | | Deposit date: | 2016-07-30 | | Release date: | 2017-08-16 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | A unique surface on Pat1 C-terminal domain directly interacts with Dcp2 decapping enzyme and Xrn1 5'-3' mRNA exonuclease in yeast.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5LOP
 | | Structure of the active form of /K. lactis/ Dcp1-Dcp2-Edc3 decapping complex bound to m7GDP | | Descriptor: | 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, KLLA0A11308p, KLLA0E01827p, ... | | Authors: | Charenton, C, Taverniti, V, Gaudon-Plesse, C, Back, R, Seraphin, B, Graille, M. | | Deposit date: | 2016-08-09 | | Release date: | 2016-10-05 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structure of the active form of Dcp1-Dcp2 decapping enzyme bound to m(7)GDP and its Edc3 activator.
Nat.Struct.Mol.Biol., 23, 2016
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5LON
 | | Structure of /K. lactis/ Dcp1-Dcp2 decapping complex. | | Descriptor: | KLLA0E01827p, KLLA0F23980p | | Authors: | Charenton, C, Taverniti, V, Gaudon-Plesse, C, Back, R, Seraphin, B, Graille, M. | | Deposit date: | 2016-08-09 | | Release date: | 2016-10-05 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structure of the active form of Dcp1-Dcp2 decapping enzyme bound to m(7)GDP and its Edc3 activator.
Nat.Struct.Mol.Biol., 23, 2016
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4JW2
 | | Selection of specific protein binders for pre-defined targets from an optimized library of artificial helicoidal repeat proteins (alphaRep) | | Descriptor: | 1,2-ETHANEDIOL, A3 artificial protein, bA3-2: binder of A3 protein | | Authors: | Guellouz, A, Valerio-Lepiniec, M, Urvoas, A, Chevrel, A, Graille, M, Fourati-Kammoun, Z, Desmadril, M, van Tilbeurgh, H, Minard, P. | | Deposit date: | 2013-03-27 | | Release date: | 2013-09-25 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Selection of Specific Protein Binders for Pre-Defined Targets from an Optimized Library of Artificial Helicoidal Repeat Proteins (alphaRep).
Plos One, 8, 2013
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4FZB
 | | Structure of thymidylate synthase ThyX complexed to a new inhibitor | | Descriptor: | 2-hydroxy-3-(4-methoxybenzyl)naphthalene-1,4-dione, DIMETHYL SULFOXIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Basta, T, Boum, Y, Briffotaux, J, Becker, H.F, Lamarre-Jouenne, I, Lambry, J.C, Skouloubris, S, Liebl, U, van Tilbeurgh, H, Graille, M, Myllylkallio, H. | | Deposit date: | 2012-07-06 | | Release date: | 2013-05-22 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.59 Å) | | Cite: | Mechanistic and structural basis for inhibition of thymidylate synthase ThyX.
Open Biology, 2, 2012
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4LUN
 | | Structure of the N-terminal mIF4G domain from S. cerevisiae Upf2, a protein involved in the degradation of mRNAs containing premature stop codons | | Descriptor: | CHLORIDE ION, Nonsense-mediated mRNA decay protein 2 | | Authors: | Fourati, Z, Roy, B, Millan, C, Courreux, P.D, Kervestin, S, van Tilbeurgh, H, He, F, Uson, I, Jacobson, A, Graille, M. | | Deposit date: | 2013-07-25 | | Release date: | 2014-07-30 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.641 Å) | | Cite: | A highly conserved region essential for NMD in the Upf2 N-terminal domain.
J.Mol.Biol., 426, 2014
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2IVO
 | | Structure of UP1 protein | | Descriptor: | TUNGSTATE(VI)ION, UP1 | | Authors: | Hecker, A, Leulliot, N, Graille, M, Dorlet, P, Quevillon-Cheruel, S, Ulryck, N, Van Tilbeurgh, H, Forterre, P. | | Deposit date: | 2006-06-14 | | Release date: | 2007-07-31 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | An Archaeal Orthologue of the Universal Protein Kae1 is an Iron Metalloprotein which Exhibits Atypical DNA-Binding Properties and Apurinic-Endonuclease Activity in Vitro.
Nucleic Acids Res., 35, 2007
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4HR1
 | | Structure of PAV1-137, a protein from the virus PAV1 that infects Pyrococcus abyssi. | | Descriptor: | Putative uncharacterized protein | | Authors: | Leulliot, N, Quevillon-Cheruel, S, Graille, M, Geslin, C, Flament, D, Romancer, M.L, Tilbeurgh, H.V. | | Deposit date: | 2012-10-26 | | Release date: | 2013-06-19 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of PAV1-137: a protein from the virus PAV1 that infects Pyrococcus abyssi
Archaea, 2013, 2013
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3P26
 | | Crystal structure of S. cerevisiae Hbs1 protein (apo-form), a translational GTPase involved in RNA quality control pathways and interacting with Dom34/Pelota | | Descriptor: | Elongation factor 1 alpha-like protein | | Authors: | van den Elzen, A, Henri, J, Lazar, N, Gas, M.E, Durand, D, Lacroute, F, Nicaise, M, van Tilbeurgh, H, Sraphin, B, Graille, M, Paris-Sud Yeast Structural Genomics (YSG) | | Deposit date: | 2010-10-01 | | Release date: | 2010-11-17 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Dissection of Dom34-Hbs1 reveals independent functions in two RNA quality control pathways.
Nat.Struct.Mol.Biol., 17, 2010
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3P27
 | | Crystal structure of S. cerevisiae Hbs1 protein (GDP-bound form), a translational GTPase involved in RNA quality control pathways and interacting with Dom34/Pelota | | Descriptor: | Elongation factor 1 alpha-like protein, GUANOSINE-5'-DIPHOSPHATE | | Authors: | van den Elzen, A, Henri, J, Lazar, N, Gas, M.E, Durand, D, Lacroute, F, Nicaise, M, van Tilbeurgh, H, Sraphin, B, Graille, M, Paris-Sud Yeast Structural Genomics (YSG) | | Deposit date: | 2010-10-01 | | Release date: | 2010-11-17 | | Last modified: | 2012-03-14 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | Dissection of Dom34-Hbs1 reveals independent functions in two RNA quality control pathways.
Nat.Struct.Mol.Biol., 17, 2010
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3Q87
 | | Structure of E. cuniculi Mtq2-Trm112 complex responible for the methylation of eRF1 translation termination factor | | Descriptor: | N6 adenine specific DNA methylase, Putative uncharacterized protein ECU08_1170, S-ADENOSYLMETHIONINE, ... | | Authors: | Liger, D, Mora, L, Lazar, N, Figaro, S, Henri, J, Scrima, N, Buckingham, R.H, van Tilbeurgh, H, Heurgue-Hamard, V, Graille, M. | | Deposit date: | 2011-01-06 | | Release date: | 2011-05-18 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.997 Å) | | Cite: | Mechanism of activation of methyltransferases involved in translation by the Trm112 'hub' protein
Nucleic Acids Res., 2011
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3QTN
 | | Structure of S. pombe nuclear import adaptor Nro1 (Space group P6522) | | Descriptor: | Uncharacterized protein C4B3.07 | | Authors: | Rispal, D, Henri, J, van Tilbeurgh, H, Graille, M, Seraphin, B. | | Deposit date: | 2011-02-23 | | Release date: | 2011-09-21 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.499 Å) | | Cite: | Structural and functional analysis of Nro1/Ett1: a protein involved in translation termination in S. cerevisiae and in O2-mediated gene control in S. pombe
Rna, 17, 2011
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3QTM
 | | Structure of S. pombe nuclear import adaptor Nro1 (Space group P21) | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, SULFATE ION, ... | | Authors: | Rispal, D, Henri, J, van Tilbeurgh, H, Graille, M, Seraphin, B. | | Deposit date: | 2011-02-23 | | Release date: | 2011-09-21 | | Last modified: | 2018-01-03 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structural and functional analysis of Nro1/Ett1: a protein involved in translation termination in S. cerevisiae and in O2-mediated gene control in S. pombe
Rna, 17, 2011
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3LTM
 | | Structure of a new family of artificial alpha helicoidal repeat proteins (alpha-Rep) based on thermostable HEAT-like repeats | | Descriptor: | Alpha-Rep4, DODECAETHYLENE GLYCOL, GLYCEROL, ... | | Authors: | Urvoas, A, Guellouz, A, Graille, M, van Tilbeurgh, H, Desmadril, M, Minard, P. | | Deposit date: | 2010-02-16 | | Release date: | 2010-10-13 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Design, production and molecular structure of a new family of artificial alpha-helicoidal repeat proteins ( alpha Rep) based on thermostable HEAT-like repeats
J.Mol.Biol., 404, 2010
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3LTJ
 | | Structure of a new family of artificial alpha helicoidal repeat proteins (alpha-Rep) based on thermostable HEAT-like repeats | | Descriptor: | AlphaRep-4 | | Authors: | Urvoas, A, Guellouz, A, Graille, M, van Tilbeurgh, H, Desmadril, M, Minard, P. | | Deposit date: | 2010-02-16 | | Release date: | 2010-10-13 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Design, production and molecular structure of a new family of artificial alpha-helicoidal repeat proteins ( alpha Rep) based on thermostable HEAT-like repeats
J.Mol.Biol., 404, 2010
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5LM5
 | | Structure of C-terminal domain from S. cerevisiae Pat1 decapping activator bound to Dcp2 HLM2 peptide (region 435-451) | | Descriptor: | DNA topoisomerase 2-associated protein PAT1, mRNA decapping protein 2 | | Authors: | Charenton, C, Gaudon-Plesse, C, Fourati, Z, Taverniti, V, Back, R, Kolesnikova, O, Seraphin, B, Graille, M. | | Deposit date: | 2016-07-29 | | Release date: | 2017-08-16 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | A unique surface on Pat1 C-terminal domain directly interacts with Dcp2 decapping enzyme and Xrn1 5'-3' mRNA exonuclease in yeast.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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2XGL
 | | The X-ray structure of the Escherichia coli colicin M immunity protein demonstrates the presence of a disulphide bridge, which is functionally essential | | Descriptor: | CADMIUM ION, CHLORIDE ION, COLICIN-M IMMUNITY PROTEIN, ... | | Authors: | Gerard, F, Brooks, M.A, Barreteau, H, Touze, T, Graille, M, Bouhss, A, Blanot, D, Tilbeurgh, H.v, Mengin-Lecreulx, D. | | Deposit date: | 2010-06-07 | | Release date: | 2010-11-17 | | Last modified: | 2018-03-07 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | X-Ray Structure and Site-Directed Mutagenesis Analysis of the Escherichia Coli Colicin M Immunity Protein.
J.Bacteriol., 193, 2011
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1XE7
 | | Crystal structure of the YML079w protein from Saccharomyces cerevisiae reveals a new sequence family of the jelly roll fold | | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, GUANINE, ... | | Authors: | Zhou, C.-Z, Meyer, P, Quevillon-Cheruel, S, Li de La Sierra-Gallay, I, Collinet, B, Graille, M, Leulliot, N, Sorel, I, Janin, J, Van Tilbeurgh, H. | | Deposit date: | 2004-09-09 | | Release date: | 2005-01-11 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Crystal structure of the YML079w protein from Saccharomyces cerevisiae reveals a new sequence family of the jelly-roll fold
Protein Sci., 14, 2005
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1OCS
 | | Crystal structure of the yeast PX-doamin protein Grd19p (sorting nexin3) complexed to phosphatidylinosytol-3-phosphate. | | Descriptor: | GLYCEROL, SORTING NEXIN GRD19 | | Authors: | Zhou, C.Z, Li De La Sierra-Gallay, I, Cheruel, S, Collinet, B, Minard, P, Blondeau, K, Henkes, G, Aufrere, R, Leulliot, N, Graille, M, Sorel, I, Savarin, P, De La Torre, F, Poupon, A, Janin, J, Van Tilbeurgh, H. | | Deposit date: | 2003-02-10 | | Release date: | 2003-12-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | Crystal Structure of the Yeast Phox Homology (Px) Protein Grd19P (Sorting Nexin 3) Complexed to Phosphatidylinositol-3-Phosphate
J.Biol.Chem., 278, 2003
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1OCU
 | | Crystal structure of the yeast PX-domain protein Grd19p (sorting nexin 3) complexed to phosphatidylinosytol-3-phosphate. | | Descriptor: | 2-(BUTANOYLOXY)-1-{[(HYDROXY{[2,3,4,6-TETRAHYDROXY-5-(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTANOATE, SORTING NEXIN | | Authors: | Zhou, C.Z, Li de La Sierra-Gallay, I, Cheruel, S, Collinet, B, Minard, P, Blondeau, K, Henkes, G, Aufrere, R, Leulliot, N, Graille, M, Sorel, I, Savarin, P, de la Torre, F, Poupon, A, Janin, J, van Tilbeurgh, H. | | Deposit date: | 2003-02-10 | | Release date: | 2003-12-12 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of the yeast Phox homology (PX) domain protein Grd19p complexed to phosphatidylinositol-3-phosphate.
J. Biol. Chem., 278, 2003
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2VUG
 | | The structure of an archaeal homodimeric RNA ligase | | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, PAB1020, ... | | Authors: | Brooks, M.A, Meslet-Cladiere, L, Graille, M, Kuhn, J, Blondeau, K, Myllykallio, H, van Tilbeurgh, H. | | Deposit date: | 2008-05-26 | | Release date: | 2008-06-03 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | The structure of an archaeal homodimeric ligase which has RNA circularization activity.
Protein Sci., 17, 2008
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2IVN
 | | Structure of UP1 protein | | Descriptor: | GLYCEROL, MAGNESIUM ION, O-SIALOGLYCOPROTEIN ENDOPEPTIDASE, ... | | Authors: | Hecker, A, Leulliot, N, Graille, M, Dorlet, P, Quevillon-Cheruel, S, Ulryck, N, Van Tilbeurgh, H, Forterre, P. | | Deposit date: | 2006-06-14 | | Release date: | 2007-07-31 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | An Archaeal Orthologue of the Universal Protein Kae1 is an Iron Metalloprotein which Exhibits Atypical DNA-Binding Properties and Apurinic-Endonuclease Activity in Vitro.
Nucleic Acids Res., 35, 2007
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2J6A
 | | Structure of S. cerevisiae Trm112 protein, a methyltransferase activator | | Descriptor: | 1,2-ETHANEDIOL, PROTEIN TRM112, ZINC ION | | Authors: | Heurgue-Hamard, V, Graille, M, Scrima, N, Ulryck, N, Champ, S, Van Tilbeurgh, H, Buckingham, R.H. | | Deposit date: | 2006-09-27 | | Release date: | 2006-09-28 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The Zinc Finger Protein Ynr046W is Plurifunctional and a Component of the Erf1 Methyltransferase in Yeast.
J.Biol.Chem., 281, 2006
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2IVP
 | | Structure of UP1 protein | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, FE (II) ION, O-SIALOGLYCOPROTEIN ENDOPEPTIDASE | | Authors: | Hecker, A, Leulliot, N, Graille, M, Dorlet, P, Quevillon-Cheruel, S, Ulryck, N, Van Tilbeurgh, H, Forterre, P. | | Deposit date: | 2006-06-14 | | Release date: | 2007-07-31 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | An Archaeal Orthologue of the Universal Protein Kae1 is an Iron Metalloprotein which Exhibits Atypical DNA-Binding Properties and Apurinic-Endonuclease Activity in Vitro.
Nucleic Acids Res., 35, 2007
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2V3J
 | | The yeast ribosome synthesis factor Emg1 alpha beta knot fold methyltransferase | | Descriptor: | ESSENTIAL FOR MITOTIC GROWTH 1, SULFATE ION | | Authors: | Leulliot, N, Bohnsack, M.T, Graille, M, Tollervey, D, Van Tilbeurgh, H. | | Deposit date: | 2007-06-18 | | Release date: | 2007-12-04 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The Yeast Ribosome Synthesis Factor Emg1 is a Novel Member of the Superfamily of Alpha/Beta Knot Fold Methyltransferases.
Nucleic Acids Res., 36, 2008
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