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PDB: 49 件

4I29
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Binary complex of mouse TdT with ssDNA and Mn++
分子名称: 5'-D(*AP*AP*(8BA)P*AP*A)-3', DNA nucleotidylexotransferase, MANGANESE (II) ION, ...
著者Gouge, J, Delarue, M.
登録日2012-11-21
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism.
J.Mol.Biol., 425, 2013
4I2B
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BU of 4i2b by Molmil
Ternary complex of mouse TdT with ssDNA and AMPcPP
分子名称: 5'-D(P*AP*AP*AP*AP*A)-3', DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA nucleotidylexotransferase, ...
著者Gouge, J, Delarue, M.
登録日2012-11-21
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism.
J.Mol.Biol., 425, 2013
4I2G
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BU of 4i2g by Molmil
Binary complex of mouse TdT with ssDNA
分子名称: 5'-D(P*AP*AP*AP*AP*A)-3', COBALT (II) ION, DNA nucleotidylexotransferase, ...
著者Gouge, J, Delarue, M.
登録日2012-11-21
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism.
J.Mol.Biol., 425, 2013
4I2A
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BU of 4i2a by Molmil
Binary complex of mouse TdT with ssDNA in absence of divalent transition metal ion
分子名称: 5'-D(*AP*AP*(BRU)P*AP*A)-3', DNA nucleotidylexotransferase, MAGNESIUM ION, ...
著者Gouge, J, Delarue, M.
登録日2012-11-21
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism.
J.Mol.Biol., 425, 2013
4I2J
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BU of 4i2j by Molmil
Binary complex of mouse TdT with dCTP
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA nucleotidylexotransferase, ZINC ION
著者Gouge, J, Delarue, M.
登録日2012-11-21
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism.
J.Mol.Biol., 425, 2013
4I2H
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BU of 4i2h by Molmil
Ternary complex of mouse TdT with ssDNA and AMPcPP
分子名称: 5'-D(P*AP*AP*AP*AP*A)-3', DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA nucleotidylexotransferase, ...
著者Gouge, J, Delarue, M.
登録日2012-11-21
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism.
J.Mol.Biol., 425, 2013
4I2E
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BU of 4i2e by Molmil
Ternary complex of mouse TdT with ssDNA and AMPcPP
分子名称: 5'-D(*AP*AP*AP*AP*A)-3', COBALT (II) ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ...
著者Gouge, J, Delarue, M.
登録日2012-11-21
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism.
J.Mol.Biol., 425, 2013
4I2F
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BU of 4i2f by Molmil
Binary complex of mouse TdT with ssDNA
分子名称: 5'-D(P*AP*AP*AP*AP*A)-3', DNA nucleotidylexotransferase, MAGNESIUM ION, ...
著者Gouge, J, Delarue, M.
登録日2012-11-21
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism.
J.Mol.Biol., 425, 2013
4I27
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BU of 4i27 by Molmil
Ternary complex of mouse TdT with ssDNA and incoming nucleotide
分子名称: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*AP*AP*AP*AP*T)-3', DNA nucleotidylexotransferase, ...
著者Gouge, J, Delarue, M.
登録日2012-11-21
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism.
J.Mol.Biol., 425, 2013
4I28
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BU of 4i28 by Molmil
Binary complex of mouse TdT with ssDNA and Zn++
分子名称: 5'-D(*AP*AP*AP*AP*A)-3', DNA nucleotidylexotransferase, MAGNESIUM ION, ...
著者Gouge, J, Delarue, M.
登録日2012-11-21
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism.
J.Mol.Biol., 425, 2013
4I2C
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BU of 4i2c by Molmil
Ternary complex of mouse TdT with ssDNA and AMPcPP
分子名称: 5'-D(*AP*AP*AP*AP*A)-3', DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA nucleotidylexotransferase, ...
著者Gouge, J, Delarue, M.
登録日2012-11-21
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism.
J.Mol.Biol., 425, 2013
4IQT
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BU of 4iqt by Molmil
Tdt core in complex with inhibitor 6-[4-(3-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid
分子名称: 6-[4-(3-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid, DNA nucleotidylexotransferase
著者Gouge, J, Delarue, M.
登録日2013-01-13
公開日2013-09-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献New nucleotide-competitive non-nucleoside inhibitors of terminal deoxynucleotidyl transferase: discovery, characterization, and crystal structure in complex with the target.
J.Med.Chem., 56, 2013
4IQU
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BU of 4iqu by Molmil
Tdt core in complex with inhibitor (2Z,5E)-6-[4-(4-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid
分子名称: (2Z,5E)-6-[4-(4-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid, DNA nucleotidylexotransferase, SODIUM ION
著者Gouge, J, Delarue, M.
登録日2013-01-13
公開日2013-09-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献New nucleotide-competitive non-nucleoside inhibitors of terminal deoxynucleotidyl transferase: discovery, characterization, and crystal structure in complex with the target.
J.Med.Chem., 56, 2013
4IQV
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BU of 4iqv by Molmil
Tdt core in complex with inhibitor 6-[4-(3-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid and ssDNA
分子名称: 5'-D(*GP*CP*CP*G)-3', 6-[4-(3-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid, DNA nucleotidylexotransferase, ...
著者Gouge, J, Delarue, M.
登録日2013-01-13
公開日2013-09-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献New nucleotide-competitive non-nucleoside inhibitors of terminal deoxynucleotidyl transferase: discovery, characterization, and crystal structure in complex with the target.
J.Med.Chem., 56, 2013
4IQW
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BU of 4iqw by Molmil
Tdt core in complex with inhibitor (2Z,5E)-6-[4-(4-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid and ssDNA
分子名称: (2Z,5E)-6-[4-(4-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid, 5'-D(*GP*CP*CP*G)-3', DNA nucleotidylexotransferase, ...
著者Gouge, J, Delarue, M.
登録日2013-01-13
公開日2013-09-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献New nucleotide-competitive non-nucleoside inhibitors of terminal deoxynucleotidyl transferase: discovery, characterization, and crystal structure in complex with the target.
J.Med.Chem., 56, 2013
4ROE
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BU of 4roe by Molmil
Human TFIIB-related factor 2 (Brf2) and TBP bound to RPPH1 promoter
分子名称: MAGNESIUM ION, Non-template strand, TATA-box-binding protein, ...
著者Vannini, A, Gouge, J, Satia, K, Guthertz, N.
登録日2014-10-28
公開日2015-12-30
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Redox Signaling by the RNA Polymerase III TFIIB-Related Factor Brf2.
Cell(Cambridge,Mass.), 163, 2015
4ROD
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BU of 4rod by Molmil
Human TFIIB-related factor 2 (Brf2) and TBP bound to TRNAU1 promoter
分子名称: Non-template strand, TATA-box-binding protein, Template strand, ...
著者Vannini, A, Gouge, J, Satia, K, Guthertz, N.
登録日2014-10-28
公開日2015-12-30
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Redox Signaling by the RNA Polymerase III TFIIB-Related Factor Brf2.
Cell(Cambridge,Mass.), 163, 2015
4ROC
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BU of 4roc by Molmil
Human TFIIB-related factor 2 (Brf2) and TBP bound to U6#2 promoter
分子名称: MAGNESIUM ION, Non-template strand, TATA-box-binding protein, ...
著者Vannini, A, Gouge, J, Satia, K, Guthertz, N.
登録日2014-10-28
公開日2015-12-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Redox Signaling by the RNA Polymerase III TFIIB-Related Factor Brf2.
Cell(Cambridge,Mass.), 163, 2015
7ZX7
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BU of 7zx7 by Molmil
Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (CC)
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ...
著者Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P.
登録日2022-05-20
公開日2022-11-30
最終更新日2022-12-28
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II.
Nat.Struct.Mol.Biol., 29, 2022
7ZWD
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BU of 7zwd by Molmil
Structure of SNAPc containing Pol II pre-initiation complex bound to U5 snRNA promoter (CC)
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ...
著者Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P.
登録日2022-05-19
公開日2022-11-30
最終更新日2022-12-28
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II.
Nat.Struct.Mol.Biol., 29, 2022
7ZX8
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BU of 7zx8 by Molmil
Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (OC)
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ...
著者Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P.
登録日2022-05-20
公開日2022-12-07
最終更新日2022-12-28
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II.
Nat.Struct.Mol.Biol., 29, 2022
7ZXE
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BU of 7zxe by Molmil
Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (OC)
分子名称: Non-template strand, TATA-box-binding protein, Template strand, ...
著者Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P.
登録日2022-05-20
公開日2022-11-30
最終更新日2022-12-28
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II.
Nat.Struct.Mol.Biol., 29, 2022
7AST
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BU of 7ast by Molmil
Apo Human RNA Polymerase III
分子名称: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
著者Ramsay, E.P, Abascal-Palacios, G, Daiss, J.L, King, H, Gouge, J, Pilsl, M, Beuron, F, Morris, E, Gunkel, P, Engel, C, Vannini, A.
登録日2020-10-28
公開日2020-12-23
最終更新日2020-12-30
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structure of human RNA polymerase III.
Nat Commun, 11, 2020
7ZWC
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BU of 7zwc by Molmil
Structure of SNAPc:TBP-TFIIA-TFIIB sub-complex bound to U5 snRNA promoter
分子名称: Non-template strand, TATA-box-binding protein, Template strand, ...
著者Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P.
登録日2022-05-19
公開日2022-11-30
最終更新日2022-12-28
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II.
Nat.Struct.Mol.Biol., 29, 2022
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