7Z0G
 
 | | CPAP:TUBULIN:IE5 ALPHAREP COMPLEX P1 SPACE GROUP | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Centromere protein J, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Gigant, B, Campanacci, V. | | Deposit date: | 2022-02-22 | | Release date: | 2022-04-13 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (3.487 Å) | | Cite: | Structural convergence for tubulin binding of CPAP and vinca domain microtubule inhibitors.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7Z0F
 | | CPAP:S-TUBULIN:IIH5 ALPHAREP COMPLEX | | Descriptor: | Centromere protein J, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Gigant, B, Campanacci, V. | | Deposit date: | 2022-02-22 | | Release date: | 2022-04-13 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.396 Å) | | Cite: | Structural convergence for tubulin binding of CPAP and vinca domain microtubule inhibitors.
Proc.Natl.Acad.Sci.USA, 119, 2022
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1KN2
 | | CATALYTIC ANTIBODY D2.3 COMPLEX | | Descriptor: | IG ANTIBODY D2.3 (HEAVY CHAIN), IG ANTIBODY D2.3 (LIGHT CHAIN), PARA-NITROPHENYL PHOSPHONOBUTANOYL L-ALANINE, ... | | Authors: | Gigant, B, Knossow, M. | | Deposit date: | 2001-12-18 | | Release date: | 2002-03-13 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Remarkable remote chiral recognition in a reaction mediated by a catalytic antibody.
J.Am.Chem.Soc., 124, 2002
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1KN4
 | | CATALYTIC ANTIBODY D2.3 COMPLEX | | Descriptor: | IG ANTIBODY D2.3 (HEAVY CHAIN), IG ANTIBODY D2.3 (LIGHT CHAIN), PARA-NITROPHENYL PHOSPHONOBUTANOYL D-ALANINE, ... | | Authors: | Gigant, B, Knossow, M. | | Deposit date: | 2001-12-18 | | Release date: | 2002-03-13 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Remarkable remote chiral recognition in a reaction mediated by a catalytic antibody.
J.Am.Chem.Soc., 124, 2002
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1CT8
 | | CATALYTIC ANTIBODY 7C8 COMPLEX | | Descriptor: | 7C8 FAB FRAGMENT; LONG CHAIN, 7C8 FAB FRAGMENT; SHORT CHAIN, SULFATE ION, ... | | Authors: | Gigant, B, Tsumuraya, T, Fujii, I, Knossow, M. | | Deposit date: | 1999-08-20 | | Release date: | 1999-11-10 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Diverse structural solutions to catalysis in a family of antibodies.
Structure Fold.Des., 7, 1999
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6GX7
 | | Tubulin-CopN-alphaRep complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Gigant, B, Campanacci, V. | | Deposit date: | 2018-06-26 | | Release date: | 2019-04-24 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3.19 Å) | | Cite: | Insight into microtubule nucleation from tubulin-capping proteins.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6GVN
 | | Tubulin:TM-3 DARPin complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Gigant, B, Cantos Fernandes, S, Campanacci, V. | | Deposit date: | 2018-06-21 | | Release date: | 2019-04-24 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.69 Å) | | Cite: | Insight into microtubule nucleation from tubulin-capping proteins.
Proc.Natl.Acad.Sci.USA, 116, 2019
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1FFX
 | | TUBULIN:STATHMIN-LIKE DOMAIN COMPLEX | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, PROTEIN (STATHMIN-LIKE DOMAIN OF RB3), ... | | Authors: | Gigant, B, Martin-Barbey, C, Knossow, M. | | Deposit date: | 2000-07-26 | | Release date: | 2000-09-27 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (3.95 Å) | | Cite: | The 4 A X-ray structure of a tubulin:stathmin-like domain complex.
Cell(Cambridge,Mass.), 102, 2000
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6GVM
 | | Tubulin:F3II DARPin complex | | Descriptor: | F3II DARPIN, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Gigant, B, Campanacci, V, Cantos Fernandes, S. | | Deposit date: | 2018-06-21 | | Release date: | 2019-04-24 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Insight into microtubule nucleation from tubulin-capping proteins.
Proc.Natl.Acad.Sci.USA, 116, 2019
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4F6R
 | | Tubulin:Stathmin-like domain complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Designed ankyrin repeat protein (DARPIN) D2, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Gigant, B, Mignot, I, Knossow, M. | | Deposit date: | 2012-05-15 | | Release date: | 2012-07-18 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.64 Å) | | Cite: | Design and characterization of modular scaffolds for tubulin assembly.
J.Biol.Chem., 287, 2012
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4F61
 | | Tubulin:Stathmin-like domain complex | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Gigant, B, Mignot, I, Knossow, M. | | Deposit date: | 2012-05-14 | | Release date: | 2012-07-18 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (4.17 Å) | | Cite: | Design and characterization of modular scaffolds for tubulin assembly.
J.Biol.Chem., 287, 2012
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4HNA
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6TIS
 | | DROSOPHILA GDP-TUBULIN | | Descriptor: | GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Gigant, B. | | Deposit date: | 2019-11-22 | | Release date: | 2021-01-27 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | GTP-dependent formation of straight tubulin oligomers leads to microtubule nucleation.
J.Cell Biol., 220, 2021
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6TIZ
 | | DROSOPHILA GDP-TUBULIN Y222F MUTANT | | Descriptor: | GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Gigant, B. | | Deposit date: | 2019-11-22 | | Release date: | 2021-01-27 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.197 Å) | | Cite: | GTP-dependent formation of straight tubulin oligomers leads to microtubule nucleation.
J.Cell Biol., 220, 2021
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6TIU
 | | DROSOPHILA GTP-TUBULIN Y222F MUTANT | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Gigant, B. | | Deposit date: | 2019-11-22 | | Release date: | 2021-01-27 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.571 Å) | | Cite: | GTP-dependent formation of straight tubulin oligomers leads to microtubule nucleation.
J.Cell Biol., 220, 2021
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6TIY
 | | DROSOPHILA GMPCPP-TUBULIN | | Descriptor: | GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Gigant, B. | | Deposit date: | 2019-11-22 | | Release date: | 2021-01-27 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.293 Å) | | Cite: | GTP-dependent formation of straight tubulin oligomers leads to microtubule nucleation.
J.Cell Biol., 220, 2021
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6GWC
 | | Tubulin:iE5 alphaRep complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ALPHA-TUBULIN, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Gigant, B, Campanacci, V. | | Deposit date: | 2018-06-22 | | Release date: | 2019-01-30 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Selection and Characterization of Artificial Proteins Targeting the Tubulin alpha Subunit.
Structure, 27, 2019
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6GWD
 | | Tubulin:iiH5 alphaRep complex | | Descriptor: | ALPHA-TUBULIN, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Gigant, B, Campanacci, V. | | Deposit date: | 2018-06-22 | | Release date: | 2019-01-30 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Selection and Characterization of Artificial Proteins Targeting the Tubulin alpha Subunit.
Structure, 27, 2019
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1YEK
 | | CATALYTIC ANTIBODY D2.3 COMPLEX | | Descriptor: | P-NITROPHENOL, PROTEIN (IG ANTIBODY D2.3 (HEAVY CHAIN)), PROTEIN (IG ANTIBODY D2.3 (LIGHT CHAIN)), ... | | Authors: | Gigant, B, Knossow, M. | | Deposit date: | 1998-08-13 | | Release date: | 1999-01-13 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crossreactivity, efficiency and catalytic specificity of an esterase-like antibody.
J.Mol.Biol., 284, 1998
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1YEJ
 | | CATALYTIC ANTIBODY COMPLEX | | Descriptor: | 6-{4-[HYDROXY-(4-NITRO-PHENOXY)-PHOSPHORYL]-BUTYRYLAMINO}-HEXANOIC ACID, PROTEIN (IG ANTIBODY D2.3 (HEAVY CHAIN)), PROTEIN (IG ANTIBODY D2.3 (LIGHT CHAIN)), ... | | Authors: | Gigant, B, Knossow, M. | | Deposit date: | 1998-08-13 | | Release date: | 1999-01-13 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Crossreactivity, efficiency and catalytic specificity of an esterase-like antibody.
J.Mol.Biol., 284, 1998
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1YEG
 | | STRUCTURE OF IGG2A FAB FRAGMENT (D2.3) COMPLEXED WITH REACTION PRODUCT | | Descriptor: | ACETATE ION, IGG2A FAB FRAGMENT, PARANITROBENZYL ALCOHOL, ... | | Authors: | Gigant, B, Knossow, M. | | Deposit date: | 1997-05-29 | | Release date: | 1997-12-03 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | X-ray structures of a hydrolytic antibody and of complexes elucidate catalytic pathway from substrate binding and transition state stabilization through water attack and product release.
Proc.Natl.Acad.Sci.USA, 94, 1997
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1Z2B
 | | Tubulin-colchicine-vinblastine: stathmin-like domain complex | | Descriptor: | (2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE, 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Gigant, B, Wang, C, Ravelli, R.B.G, Roussi, F, Steinmetz, M.O, Curmi, P.A, Sobel, A, Knossow, M. | | Deposit date: | 2005-03-08 | | Release date: | 2005-05-31 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (4.1 Å) | | Cite: | Structural basis for the regulation of tubulin by vinblastine.
Nature, 435, 2005
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1YEH
 | | STRUCTURE OF IGG2A FAB FRAGMENT | | Descriptor: | FAB FRAGMENT, ZINC ION | | Authors: | Gigant, B, Knossow, M. | | Deposit date: | 1997-05-29 | | Release date: | 1997-12-03 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | X-ray structures of a hydrolytic antibody and of complexes elucidate catalytic pathway from substrate binding and transition state stabilization through water attack and product release.
Proc.Natl.Acad.Sci.USA, 94, 1997
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1YEF
 | | STRUCTURE OF IGG2A FAB FRAGMENT (D2.3) COMPLEXED WITH SUBSTRATE ANALOGUE | | Descriptor: | IGG2A FAB FRAGMENT, PARA-NITROBENZYL GLUTARYL GLYCINIC ACID, ZINC ION | | Authors: | Gigant, B, Knossow, M. | | Deposit date: | 1997-05-29 | | Release date: | 1997-12-03 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | X-ray structures of a hydrolytic antibody and of complexes elucidate catalytic pathway from substrate binding and transition state stabilization through water attack and product release.
Proc.Natl.Acad.Sci.USA, 94, 1997
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1YEI
 | | CATALYTIC ANTIBODY D2.3 COMPLEX | | Descriptor: | PARA-NITROPHENYLPHOSPHONOBUTANOYL-GLYCINE, PROTEIN (IG ANTIBODY D2.3 (HEAVY CHAIN)), PROTEIN (IG ANTIBODY D2.3 (LIGHT CHAIN)), ... | | Authors: | Gigant, B, Knossow, M. | | Deposit date: | 1998-08-13 | | Release date: | 1999-01-13 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crossreactivity, efficiency and catalytic specificity of an esterase-like antibody.
J.Mol.Biol., 284, 1998
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