8K6Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8k6y by Molmil](/molmil-images/mine/8k6y) | Serial femtosecond crystallography structure of photo dissociated CO from ba3- type cytochrome c oxidase determined by extrapolation method | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CARBON MONOXIDE, COPPER (II) ION, ... | 著者 | Safari, C, Ghosh, S, Andersson, R, Johannesson, J, Donoso, A.V, Zoric, D, Sandelin, E, Iwata, S, Neutze, R, Branden, G. | 登録日 | 2023-07-25 | 公開日 | 2023-11-15 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Time-resolved serial crystallography to track the dynamics of carbon monoxide in the active site of cytochrome c oxidase. Sci Adv, 9, 2023
|
|
8K65
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8k65 by Molmil](/molmil-images/mine/8k65) | Serial femtosecond crystallography structure of CO bound ba3- type cytochrome c oxidase without pump laser irradiation | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CARBON MONOXIDE, COPPER (II) ION, ... | 著者 | Safari, C, Ghosh, S, Andersson, R, Johannesson, J, Donoso, A.V, Bath, P, Zoric, D, Sandelin, E, Nango, E, Tanaka, R, Iwata, S, Neutze, R, Branden, G. | 登録日 | 2023-07-25 | 公開日 | 2023-11-15 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Time-resolved serial crystallography to track the dynamics of carbon monoxide in the active site of cytochrome c oxidase. Sci Adv, 9, 2023
|
|
1RAM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ram by Molmil](/molmil-images/mine/1ram) | A NOVEL DNA RECOGNITION MODE BY NF-KB P65 HOMODIMER | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, DNA (5'-D(*CP*GP*GP*CP*TP*GP*GP*AP*AP*AP*TP*TP*TP*CP*CP*AP*GP*CP*CP*G)-3'), PROTEIN (TRANSCRIPTION FACTOR NF-KB P65) | 著者 | Chen, Y.-Q, Ghosh, S, Ghosh, G. | 登録日 | 1997-11-22 | 公開日 | 1998-05-27 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | A novel DNA recognition mode by the NF-kappa B p65 homodimer. Nat.Struct.Biol., 5, 1998
|
|
1DF1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1df1 by Molmil](/molmil-images/mine/1df1) | MURINE INOSOXY DIMER WITH ISOTHIOUREA BOUND IN THE ACTIVE SITE | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ETHYLISOTHIOUREA, NITRIC OXIDE SYNTHASE, ... | 著者 | Crane, B.R, Rosenfeld, R.J, Arvai, A.S, Ghosh, D.K, Ghosh, S, Tainer, J.A, Stuehr, D.J, Getzoff, E.D. | 登録日 | 1999-11-16 | 公開日 | 1999-12-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | N-terminal domain swapping and metal ion binding in nitric oxide synthase dimerization. EMBO J., 18, 1999
|
|
4PT4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4pt4 by Molmil](/molmil-images/mine/4pt4) | Crystal structure Analysis of N terminal region containing the dimerization domain and DNA binding domain of HU protein(Histone like protein-DNA binding) from Mycobacterium tuberculosis [H37Ra] | 分子名称: | DNA-binding protein HU homolog, FORMIC ACID | 著者 | Bhowmick, T, Ramagopal, U.A, Ghosh, S, Nagaraja, V, Ramakumar, S. | 登録日 | 2014-03-10 | 公開日 | 2014-05-21 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Targeting Mycobacterium tuberculosis nucleoid-associated protein HU with structure-based inhibitors Nat Commun, 5, 2014
|
|
2XHB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xhb by Molmil](/molmil-images/mine/2xhb) | Crystal structure of DNA polymerase from Thermococcus gorgonarius in complex with hypoxanthine-containing DNA | 分子名称: | 5'-D(*AP*AP*AP*AP*AP*AP*AP*AP*A)-3', DNA POLYMERASE, HYPOXANTHINE-CONTAINING DNA, ... | 著者 | Killelea, T, Ghosh, S, Tan, S.S, Heslop, P, Firbank, S.J, Kool, E.T, Connolly, B.A. | 登録日 | 2010-06-14 | 公開日 | 2010-07-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | Probing the Interaction of Archaeal DNA Polymerases with Deaminated Bases Using X-Ray Crystallography and Non-Hydrogen Bonding Isosteric Base Analogues. Biochemistry, 49, 2010
|
|
6VDE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vde by Molmil](/molmil-images/mine/6vde) | Full-length M. smegmatis Pol1 | 分子名称: | DNA polymerase I, MANGANESE (II) ION | 著者 | Shuman, S, Goldgur, Y, Ghosh, S. | 登録日 | 2019-12-24 | 公開日 | 2020-02-12 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.713 Å) | 主引用文献 | Mycobacterial DNA polymerase I: activities and crystal structures of the POL domain as apoenzyme and in complex with a DNA primer-template and of the full-length FEN/EXO-POL enzyme. Nucleic Acids Res., 48, 2020
|
|
6VDC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vdc by Molmil](/molmil-images/mine/6vdc) | POL domain of Pol1 from M. smegmatis | 分子名称: | DNA polymerase I, MANGANESE (II) ION | 著者 | Shuman, S, Goldgur, Y, Ghosh, S. | 登録日 | 2019-12-24 | 公開日 | 2020-02-12 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.402 Å) | 主引用文献 | Mycobacterial DNA polymerase I: activities and crystal structures of the POL domain as apoenzyme and in complex with a DNA primer-template and of the full-length FEN/EXO-POL enzyme. Nucleic Acids Res., 48, 2020
|
|
6VDD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vdd by Molmil](/molmil-images/mine/6vdd) | POL domain of Pol1 from M. smegmatis complex with DNA primer-template and dNTP | 分子名称: | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*A*(DCT))-3'), DNA (5'-D(P*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), ... | 著者 | Shuman, S, Goldgur, Y, Ghosh, S. | 登録日 | 2019-12-24 | 公開日 | 2020-02-12 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Mycobacterial DNA polymerase I: activities and crystal structures of the POL domain as apoenzyme and in complex with a DNA primer-template and of the full-length FEN/EXO-POL enzyme. Nucleic Acids Res., 48, 2020
|
|
4O8W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4o8w by Molmil](/molmil-images/mine/4o8w) | Crystal Structure of the GerD spore germination protein | 分子名称: | Spore germination protein | 著者 | Li, Y, Jin, K, Ghosh, S, Devarakonda, P, Carlson, K, Davis, A, Stewart, K, Cammett, E, Rossi, P.P, Setlow, B, Lu, M, Setlow, P, Hao, B. | 登録日 | 2013-12-30 | 公開日 | 2014-03-19 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.293 Å) | 主引用文献 | Structural and Functional Analysis of the GerD Spore Germination Protein of Bacillus Species. J.Mol.Biol., 426, 2014
|
|
6EWN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ewn by Molmil](/molmil-images/mine/6ewn) | HspA from Thermosynechococcus vulcanus in the presence of 2M urea with initial stages of denaturation | 分子名称: | HspA, UREA | 著者 | Adir, N, Ghosh, S, Salama, F, Dines, M. | 登録日 | 2017-11-06 | 公開日 | 2018-10-17 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Biophysical and structural characterization of the small heat shock protein HspA from Thermosynechococcus vulcanus in 2 M urea. Biochim Biophys Acta Proteins Proteom, 1867, 2019
|
|
3TTJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ttj by Molmil](/molmil-images/mine/3ttj) | Crystal Structure of JNK3 complexed with CC-359, a JNK inhibitor for the prevention of ischemia-reperfusion injury | 分子名称: | 9-cyclopentyl-N~8~-(2-fluorophenyl)-N~2~-(4-methoxyphenyl)-9H-purine-2,8-diamine, Mitogen-activated protein kinase 10 | 著者 | Plantevin-Krenitsky, V, Delgado, M, Nadolny, L, Sahasrabudhe, K, Ayala, S, Clareen, S, Hilgraf, R, Albers, R, Kois, A, Hughes, K, Wright, J, Nowakowski, J, Sudbeck, E, Ghosh, S, Bahmanyar, S, Chamberlain, P, Muir, J, Cathers, B.E, Giegel, D, Xu, L, Celeridad, M, Moghaddam, M, Khatsenko, O, Omholt, P, Katz, J, Pai, S, Fan, R, Tang, Y, Shirley, M.A, Benish, B, Blease, K, Raymon, H, Bhagwat, S, Bennett, B, Satoh, Y. | 登録日 | 2011-09-14 | 公開日 | 2012-01-25 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Aminopurine based JNK inhibitors for the prevention of ischemia reperfusion injury. Bioorg.Med.Chem.Lett., 22, 2012
|
|
1FN0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1fn0 by Molmil](/molmil-images/mine/1fn0) | STRUCTURE OF A MUTANT WINGED BEAN CHYMOTRYPSIN INHIBITOR PROTEIN, N14D. | 分子名称: | CHYMOTRYPSIN INHIBITOR 3, SULFATE ION | 著者 | Dattagupta, J.K, Chakrabarti, C, Ravichandran, S, Dasgupta, J, Ghosh, S. | 登録日 | 2000-08-19 | 公開日 | 2001-02-19 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The role of Asn14 in the stability and conformation of the reactive-site loop of winged bean chymotrypsin inhibitor: crystal structures of two point mutants Asn14-->Lys and Asn14-->Asp. PROTEIN ENG., 14, 2001
|
|
1FMZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1fmz by Molmil](/molmil-images/mine/1fmz) | CRYSTAL STRUCTURE OF A MUTANT WINGED BEAN CHYMOTRYPSIN INHIBITOR PROTEIN, N14K. | 分子名称: | CHYMOTRYPSIN INHIBITOR 3, SULFATE ION | 著者 | Dattagupta, J.K, Chakrabarti, C, Ravichandran, S, Dasgupta, J, Ghosh, S. | 登録日 | 2000-08-19 | 公開日 | 2001-02-19 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | The role of Asn14 in the stability and conformation of the reactive-site loop of winged bean chymotrypsin inhibitor: crystal structures of two point mutants Asn14-->Lys and Asn14-->Asp. PROTEIN ENG., 14, 2001
|
|
1EYL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1eyl by Molmil](/molmil-images/mine/1eyl) | STRUCTURE OF A RECOMBINANT WINGED BEAN CHYMOTRYPSIN INHIBITOR | 分子名称: | CHYMOTRYPSIN INHIBITOR, SULFATE ION | 著者 | Dattagupta, J.K, Chakrabarti, C, Ravichandran, S, Ghosh, S. | 登録日 | 2000-05-07 | 公開日 | 2000-05-24 | 最終更新日 | 2022-12-21 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The role of Asn14 in the stability and conformation of the reactive-site loop of winged bean chymotrypsin inhibitor: crystal structures of two point mutants Asn14-->Lys and Asn14-->Asp. Protein Eng., 14, 2001
|
|
3Q0G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3q0g by Molmil](/molmil-images/mine/3q0g) | Crystal Structure of the Mycobacterium tuberculosis Crotonase Bound to a Reaction Intermediate Derived from Crotonyl CoA | 分子名称: | Butyryl Coenzyme A, COENZYME A, GLYCEROL, ... | 著者 | Bruning, J.B, Delgado, E, Ghosh, S, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2010-12-15 | 公開日 | 2012-01-25 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Crystal Structure of the Prokaryotic Crotonase To be Published
|
|
3Q0J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3q0j by Molmil](/molmil-images/mine/3q0j) | |
3PZK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3pzk by Molmil](/molmil-images/mine/3pzk) | |
3QRF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3qrf by Molmil](/molmil-images/mine/3qrf) | Structure of a domain-swapped FOXP3 dimer | 分子名称: | Forkhead box protein P3, MAGNESIUM ION, Nuclear factor of activated T-cells, ... | 著者 | Bandukwala, H.S, Wu, Y, Feurer, M, Chen, Y, Barbosa, B, Ghosh, S, Stroud, J.C, Benoist, C, Mathis, D, Rao, A, Chen, L. | 登録日 | 2011-02-17 | 公開日 | 2011-04-20 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of a Domain-Swapped FOXP3 Dimer on DNA and Its Function in Regulatory T Cells. Immunity, 34, 2011
|
|
7VNL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vnl by Molmil](/molmil-images/mine/7vnl) | Sandercyanin mutant-F55A-Biliverdin complex | 分子名称: | BILIVERDINE IX ALPHA, Sandercyanin Fluorescent Protein, TETRAETHYLENE GLYCOL | 著者 | Yadav, K, Ghosh, S, Subramanian, R. | 登録日 | 2021-10-11 | 公開日 | 2022-05-25 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Phenylalanine stacking enhances the red fluorescence of biliverdin IX alpha on UV excitation in sandercyanin fluorescent protein. Febs Lett., 596, 2022
|
|
7VNS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7vns by Molmil](/molmil-images/mine/7vns) | |
3UE8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ue8 by Molmil](/molmil-images/mine/3ue8) | Kynurenine Aminotransferase II Inhibitors | 分子名称: | (5-hydroxy-4-{[(1-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)amino]methyl}-6-methylpyridin-3-yl)methyl dihydrogen phosphate, CHLORIDE ION, Kynurenine/alpha-aminoadipate aminotransferase, ... | 著者 | Dounay, A.B, Anderson, M, Bechle, B.M, Campbell, B.M, Claffey, M.M, Evdokimov, A, Edelweiss, E, Fonseca, K.R, Gan, X, Ghosh, S, Hayward, M.M, Horner, W, Kim, J.Y, McAllister, L.A, Pandit, J, Paradis, V, Parikh, V.D, Reese, M.R, Rong, S.B, Salafia, M.A, Schuyten, K, Strick, C.A, Tuttle, J.B, Valentine, J, Wang, H, Zawadzke, L.E, Verhoest, P.R. | 登録日 | 2011-10-28 | 公開日 | 2012-02-01 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.22 Å) | 主引用文献 | Discovery of Brain-Penetrant, Irreversible Kynurenine Aminotransferase II Inhibitors for Schizophrenia. ACS Med Chem Lett, 3, 2012
|
|
4M9F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4m9f by Molmil](/molmil-images/mine/4m9f) | Dengue virus NS2B-NS3 protease A125C variant at pH 8.5 | 分子名称: | NS2B-NS3 protease | 著者 | Yildiz, M, Ghosh, S, Bell, J.A, Sherman, W, Hardy, J.A. | 登録日 | 2013-08-14 | 公開日 | 2013-11-27 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Allosteric Inhibition of the NS2B-NS3 Protease from Dengue Virus. Acs Chem.Biol., 8, 2013
|
|
2M6O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2m6o by Molmil](/molmil-images/mine/2m6o) | The actinobacterial transcription factor RbpA binds to the principal sigma subunit of RNA polymerase | 分子名称: | Uncharacterized protein | 著者 | Liu, B, Tabib-Salazar, A, Doughty, P, Lewis, R, Ghosh, S, Parsy, M, Simpson, P, Matthews, S, Paget, M. | 登録日 | 2013-04-06 | 公開日 | 2013-05-08 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | The actinobacterial transcription factor RbpA binds to the principal sigma subunit of RNA polymerase. Nucleic Acids Res., 41, 2013
|
|
1Q54
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1q54 by Molmil](/molmil-images/mine/1q54) | STRUCTURE AND MECHANISM OF ACTION OF ISOPENTENYLPYROPHOSPHATE-DIMETHYLALLYLPYROPHOSPHATE ISOMERASE: COMPLEX WITH THE BROMOHYDRINE OF IPP | 分子名称: | 4-BROMO-3-HYDROXY-3-METHYL BUTYL DIPHOSPHATE, ISOPENTENYL DIPHOSPHATE DELTA-ISOMERASE, MAGNESIUM ION, ... | 著者 | Wouters, J, Oudjama, Y, Ghosh, S, Stalon, V, Droogmans, L. | 登録日 | 2003-08-06 | 公開日 | 2003-08-26 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Structure and mechanism of action of isopentenylpyrophosphate-dimethylallylpyrophosphate isomerase. J.Am.Chem.Soc., 125, 2003
|
|