Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 173 件
1TPZ
DownloadVisualize
BU of 1tpz by Molmil
Crystal Structure of IIGP1: a paradigm for interferon inducible p47 resistance GTPases
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, GUANOSINE-5'-DIPHOSPHATE, ...
著者Ghosh, A, Uthaiah, R, Howard, J, Herrmann, C, Wolf, E.
登録日2004-06-16
公開日2004-09-21
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of IIGP1; A Paradigm for Interferon-Inducible p47 Resistance GTPases
Mol.Cell, 15, 2004
1TQ4
DownloadVisualize
BU of 1tq4 by Molmil
Crystal Structure of IIGP1: a paradigm for interferon inducible p47 resistance GTPases
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, interferon-inducible GTPase
著者Ghosh, A, Uthaiah, R, Howard, J, Herrmann, C, Wolf, E.
登録日2004-06-16
公開日2004-09-21
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal Structure of IIGP1; A Paradigm for Interferon-Inducible p47 Resistance GTPases
Mol.Cell, 15, 2004
1TQ2
DownloadVisualize
BU of 1tq2 by Molmil
Crystal Structure of IIGP1: a paradigm for interferon inducible p47 resistance GTPases
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Ghosh, A, Uthaiah, R, Howard, J, Herrmann, C, Wolf, E.
登録日2004-06-16
公開日2004-09-21
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structure of IIGP1; A Paradigm for Interferon-Inducible p47 Resistance GTPases
Mol.Cell, 15, 2004
1TQ6
DownloadVisualize
BU of 1tq6 by Molmil
Crystal Structure of IIGP1: a paradigm for interferon inducible p47 resistance GTPases
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, interferon-inducible GTPase
著者Ghosh, A, Uthaiah, R, Howard, J, Herrmann, C, Wolf, E.
登録日2004-06-16
公開日2004-09-21
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structure of IIGP1; A Paradigm for Interferon-Inducible p47 Resistance GTPases
Mol.Cell, 15, 2004
5DQC
DownloadVisualize
BU of 5dqc by Molmil
Co-crystal of BACE1 with compound 0211
分子名称: Beta-secretase 1, N-[(2S,3R)-3-hydroxy-4-({(2S,3S)-3-hydroxy-1-[(2-methylpropyl)amino]-1-oxobutan-2-yl}amino)-1-phenylbutan-2-yl]-5-[methyl(methylsulfonyl)amino]-N'-[(1R)-1-phenylethyl]benzene-1,3-dicarboxamide
著者Ghosh, A.K, Bhavanam, S.R, Yen, T.-C, Cardenas, E.L, Rao, K.V, Downs, D, Huang, X, Tang, J, Mescar, A.D.
登録日2015-09-14
公開日2016-02-17
最終更新日2016-07-13
実験手法X-RAY DIFFRACTION (2.4651 Å)
主引用文献Design of Potent and Highly Selective Inhibitors for Human beta-Secretase 2 (Memapsin 1), a Target for Type 2 Diabetes.
Chem Sci, 7, 2016
4GID
DownloadVisualize
BU of 4gid by Molmil
Structure of beta-secretase complexed with inhibitor
分子名称: Beta-secretase 1, L-PROLINAMIDE, N-[(2S)-1-({(2S,3R)-3-hydroxy-1-[(2-methylpropyl)amino]-1-oxobutan-2-yl}amino)-3-phenylpropan-2-yl]-5-[methyl(methylsulfonyl)amino]-N'-[(1R)-1-phenylethyl]benzene-1,3-dicarboxamide
著者Ghosh, A, Tang, J, Venkateswara, R.K, Yadav, N, Anderson, D, Gavande, N, Huang, X, Terzyan, S.
登録日2012-08-08
公開日2012-10-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure-based design of highly selective beta-secretase inhibitors: synthesis, biological evaluation, and protein-ligand X-ray crystal structure.
J.Med.Chem., 55, 2012
4HPS
DownloadVisualize
BU of 4hps by Molmil
Crystal Structure of a Pyrrolidone-carboxylate peptidase 1 (target ID NYSGRC-012831) from Xenorhabdus bovienii SS-2004 in space group P21
分子名称: CHLORIDE ION, Pyrrolidone-carboxylate peptidase
著者Ghosh, A, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
登録日2012-10-24
公開日2012-11-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal Structure of a Pyrrolidone-carboxylate peptidase 1 (target ID NYSGRC-012831) from Xenorhabdus bovienii SS-2004 in space group P21
To be Published
3RTX
DownloadVisualize
BU of 3rtx by Molmil
Crystal structure of mammalian capping enzyme (Mce1) and Pol II CTD complex
分子名称: GUANINE, RNA Polymerase II C-terminal domain, mRNA-capping enzyme
著者Ghosh, A, Lima, C.D.
登録日2011-05-04
公開日2011-06-29
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Structural insights to how mammalian capping enzyme reads the CTD code.
Mol.Cell, 43, 2011
4H15
DownloadVisualize
BU of 4h15 by Molmil
Crystal Structure of a short chain alcohol dehydrogenase-related dehydrogenase (target ID NYSGRC-011812) from Sinorhizobium meliloti 1021 in space group P21
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, CHLORIDE ION, ...
著者Ghosh, A, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
登録日2012-09-10
公開日2012-09-19
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Crystal Structure of a short chain alcohol dehydrogenase-related dehydrogenase (target ID NYSGRC-011812) from Sinorhizobium meliloti 1021 in space group P21
To be Published
4HKM
DownloadVisualize
BU of 4hkm by Molmil
Crystal Structure of an Anthranilate Phosphoribosyltransferase (target ID NYSGRC-016600) from Xanthomonas campestris
分子名称: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, Anthranilate phosphoribosyltransferase, GLYCEROL, ...
著者Ghosh, A, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
登録日2012-10-15
公開日2012-10-31
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.953 Å)
主引用文献Crystal Structure of an Anthranilate Phosphoribosyltransferase (target ID NYSGRC-016600) from Xanthomonas campestris
To be Published
4GXH
DownloadVisualize
BU of 4gxh by Molmil
Crystal Structure of a Pyrrolidone-carboxylate peptidase 1 (target ID NYSGRC-012831) from Xenorhabdus bovienii SS-2004
分子名称: CHLORIDE ION, PHOSPHATE ION, Pyrrolidone-carboxylate peptidase
著者Ghosh, A, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
登録日2012-09-04
公開日2012-09-19
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structure of a Pyrrolidone-carboxylate peptidase 1 (target ID NYSGRC-012831) from Xenorhabdus bovienii SS-2004 (CASP Target)
To be Published
4H16
DownloadVisualize
BU of 4h16 by Molmil
Crystal Structure of a short chain alcohol dehydrogenase-related dehydrogenase (target ID NYSGRC-011812) from Sinorhizobium meliloti 1021 in space group P6422
分子名称: CHLORIDE ION, HEXAETHYLENE GLYCOL, MAGNESIUM ION, ...
著者Ghosh, A, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
登録日2012-09-10
公開日2012-09-19
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of a short chain alcohol dehydrogenase-related dehydrogenase (target ID NYSGRC-011812) from Sinorhizobium meliloti 1021 in space group P6422
To be Published
1XS7
DownloadVisualize
BU of 1xs7 by Molmil
Crystal Structure of a cycloamide-urethane-derived novel inhibitor bound to human brain memapsin 2 (beta-secretase).
分子名称: Beta-secretase 1, N-[(4S,5S,7R)-8-({(S)-1-[(BENZYLAMINO)OXOMETHYL]-2-METHYLPROPYL}AMINO)-5-HYDROXY-2,7-DIMETHYL-8-OXO-OCT-4-YL]-(4S,7S)-4 -ISOPROPYL-2,5,9-TRIOXO-1-OXA-3,6,10-TRIAZACYCLOHEXADECANE-7-CARBOXAMIDE
著者Ghosh, A, Devasamudram, T, Hong, L, DeZutter, C, Xu, X, Weerasena, V, Koelsch, G, Bilcer, G, Tang, J.
登録日2004-10-18
公開日2004-12-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure-based design of cycloamide-urethane-derived novel inhibitors of human brain memapsin 2 (beta-secretase).
Bioorg.Med.Chem.Lett., 15, 2005
2MJX
DownloadVisualize
BU of 2mjx by Molmil
Solution NMR structure of a mismatch DNA
分子名称: DNA (5'-D(*CP*GP*CP*GP*TP*AP*CP*GP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(*GP*CP*GP*CP*AP*TP*GP*CP*TP*AP*CP*GP*CP*G)-3')
著者Ghosh, A, Kumar, K.R, Bhunia, A, Chatterjee, S.
登録日2014-01-21
公開日2014-03-05
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Double GC:GC mismatch in dsDNA enhances local dynamics retaining the DNA footprint: a high-resolution NMR study
Chemmedchem, 9, 2014
2JR6
DownloadVisualize
BU of 2jr6 by Molmil
Solution structure of UPF0434 protein NMA0874. Northeast Structural Genomics Target MR32
分子名称: UPF0434 protein NMA0874
著者Ghosh, A, Singarapu, K.K, Wu, Y, Liu, G, Sukumaran, D, Chen, C.X, Nwosu, C, Owens, L, Xiao, R, Liu, J, Baran, M.C, Swapna, G, Acton, T.B, Rost, B, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG)
登録日2007-06-20
公開日2007-07-24
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of UPF0434 protein NMA0874.
To be Published
2N6M
DownloadVisualize
BU of 2n6m by Molmil
Structural elucidation of the frog skin-derived peptide Esculentin-1a[Esc(1-21)NH2] inLipopolysaccharide and correlation with their function
分子名称: Esculentin-1A
著者Ghosh, A, Bhunia, A.
登録日2015-08-26
公開日2016-03-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR structure and binding of esculentin-1a (1-21)NH2 and its diastereomer to lipopolysaccharide: Correlation with biological functions
Biochim.Biophys.Acta, 1858, 2015
3D20
DownloadVisualize
BU of 3d20 by Molmil
Crystal structure of HIV-1 mutant I54V and inhibitor DARUNAVIA
分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, CHLORIDE ION, HIV-1 Protease, ...
著者Liu, F, Kovalesky, A.Y, Tie, Y, Ghosh, A.K, Harrison, R.W, Weber, I.T.
登録日2008-05-07
公開日2008-05-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Effect of flap mutations on structure of HIV-1 protease and inhibition by saquinavir and darunavir.
J.Mol.Biol., 381, 2008
4ZFQ
DownloadVisualize
BU of 4zfq by Molmil
Structure of M. tuberculosis (3,3) L,D-Transpeptidase, LdtMt5. (Meropenen-adduct form)
分子名称: (2S,3R,4S)-4-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, DI(HYDROXYETHYL)ETHER, L,D-transpeptidase 5
著者Basta, L, Ghosh, A, Lamichhane, G, Bianchet, M.A.
登録日2015-04-21
公開日2015-09-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.799 Å)
主引用文献Loss of a Functionally and Structurally Distinct ld-Transpeptidase, LdtMt5, Compromises Cell Wall Integrity in Mycobacterium tuberculosis.
J.Biol.Chem., 290, 2015
5KAO
DownloadVisualize
BU of 5kao by Molmil
Crystal structure of wild type HIV-1 protease in complex with GRL-10413
分子名称: [(3~{a}~{S},4~{R},6~{a}~{R})-2,3,3~{a},4,5,6~{a}-hexahydrofuro[2,3-b]furan-4-yl] ~{N}-[(2~{S},3~{R})-1-(3-chloranyl-4-methoxy-phenyl)-4-[(4-methoxyphenyl)sulfonyl-(2-methylpropyl)amino]-3-oxidanyl-butan-2-yl]carbamate, protease
著者Yedidi, R.S, Delino, N.S, Das, D, Kaufman, J.D, Wingfield, P.T, Ghosh, A.K, Mitsuya, H.
登録日2016-06-01
公開日2016-08-31
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A Modified P1 Moiety Enhances In Vitro Antiviral Activity against Various Multidrug-Resistant HIV-1 Variants and In Vitro Central Nervous System Penetration Properties of a Novel Nonpeptidic Protease Inhibitor, GRL-10413.
Antimicrob.Agents Chemother., 60, 2016
1M4H
DownloadVisualize
BU of 1m4h by Molmil
Crystal Structure of Beta-secretase complexed with Inhibitor OM00-3
分子名称: Inhibitor OM00-3, beta-Secretase
著者Hong, L, Turner, R.T, Koelsch, G, Ghosh, A.K, Tang, J.
登録日2002-07-02
公開日2002-08-28
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of Memapsin 2 (beta-Secretase) in Complex with Inhibitor OM00-3
Biochemistry, 41, 2002
7RXV
DownloadVisualize
BU of 7rxv by Molmil
Human Methionine Adenosyltransferase 2A bound to Methylthioadenosine, Malonate (MLA) and MgF3
分子名称: 5'-DEOXY-5'-METHYLTHIOADENOSINE, ALANINE, GLYCEROL, ...
著者Fedorov, E, Niland, C.N, Schramm, V.L, Ghosh, A.
登録日2021-08-23
公開日2021-11-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.07 Å)
主引用文献Mechanism of Triphosphate Hydrolysis by Human MAT2A at 1.07 angstrom Resolution.
J.Am.Chem.Soc., 143, 2021
7RXW
DownloadVisualize
BU of 7rxw by Molmil
Human Methionine Adenosyltransferase 2A bound to Methylthioadenosine and inhibitor imido-diphosphate (PNP)
分子名称: 1,2-ETHANEDIOL, 5'-DEOXY-5'-METHYLTHIOADENOSINE, ALANINE, ...
著者Fedorov, E, Niland, C.N, Schramm, V.L, Ghosh, A.
登録日2021-08-23
公開日2021-11-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.07 Å)
主引用文献Mechanism of Triphosphate Hydrolysis by Human MAT2A at 1.07 angstrom Resolution.
J.Am.Chem.Soc., 143, 2021
7RXX
DownloadVisualize
BU of 7rxx by Molmil
Human Methionine Adenosyltransferase 2A bound to Methylthioadenosine and two sulfate in the active site
分子名称: 1,2-ETHANEDIOL, 3,6,9,12,15-PENTAOXAHEPTADECANE, 5'-DEOXY-5'-METHYLTHIOADENOSINE, ...
著者Fedorov, E, Niland, C.N, Schramm, V.L, Ghosh, A.
登録日2021-08-23
公開日2021-11-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Mechanism of Triphosphate Hydrolysis by Human MAT2A at 1.07 angstrom Resolution.
J.Am.Chem.Soc., 143, 2021
7RJM
DownloadVisualize
BU of 7rjm by Molmil
Crystal structure of human Bromodomain containing protein 3 (BRD3) in complex with ILF3
分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 3, Interleukin enhancer-binding factor 3
著者Fedorov, E, Islam, K, Ghosh, A.
登録日2021-07-21
公開日2022-08-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Uncovering the Bromodomain Interactome using Site-Specific Azide-Acetyllysine Photochemistry, Proteomic Profiling and Structural Characterization
Biorxiv, 2021
7RJL
DownloadVisualize
BU of 7rjl by Molmil
Crystal structure of human Bromodomain containing protein 3 (BRD3) in complex with SHMT
分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 3, GLYCEROL, ...
著者Fedorov, E, Islam, K, Ghosh, A.
登録日2021-07-21
公開日2022-08-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Uncovering the Bromodomain Interactome using Site-Specific Azide-Acetyllysine Photochemistry, Proteomic Profiling and Structural Characterization
Biorxiv, 2021

224004

件を2024-08-21に公開中

PDB statisticsPDBj update infoContact PDBjnumon