7TE3
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![BU of 7te3 by Molmil](/molmil-images/mine/7te3) | Crystal Structure of a Double Loop Deletion Mutant in gC1qR/C1qBP/HABP-1 | Descriptor: | Complement component 1 Q subcomponent-binding protein, mitochondrial | Authors: | Geisbrecht, B.V. | Deposit date: | 2022-01-04 | Release date: | 2022-06-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | gC1qR/C1qBP/HABP-1: Structural Analysis of the Trimeric Core Region, Interactions With a Novel Panel of Monoclonal Antibodies, and Their Influence on Binding to FXII. Front Immunol, 13, 2022
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3D5R
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![BU of 3d5r by Molmil](/molmil-images/mine/3d5r) | Crystal Structure of Efb-C (N138A) / C3d Complex | Descriptor: | Complement C3, Fibrinogen-binding protein | Authors: | Geisbrecht, B.V. | Deposit date: | 2008-05-16 | Release date: | 2008-09-09 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Electrostatic contributions drive the interaction between Staphylococcus aureus protein Efb-C and its complement target C3d. Protein Sci., 17, 2008
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3D5S
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![BU of 3d5s by Molmil](/molmil-images/mine/3d5s) | Crystal Structure of Efb-C (R131A) / C3d Complex | Descriptor: | Complement C3, Fibrinogen-binding protein | Authors: | Geisbrecht, B.V. | Deposit date: | 2008-05-16 | Release date: | 2008-09-16 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Electrostatic contributions drive the interaction between Staphylococcus aureus protein Efb-C and its complement target C3d. Protein Sci., 17, 2008
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8TYP
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![BU of 8typ by Molmil](/molmil-images/mine/8typ) | Complement Protease C1s Inhibited by 6-(4-phenylpiperazin-1-yl)pyridine-3-carboximidamide | Descriptor: | 6-(4-phenylpiperazin-1-yl)pyridine-3-carboximidamide, Complement C1s subcomponent, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Geisbrecht, B.V. | Deposit date: | 2023-08-25 | Release date: | 2023-11-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Inhibition of the C1s Protease and the Classical Complement Pathway by 6-(4-Phenylpiperazin-1-yl)Pyridine-3-Carboximidamide and Chemical Analogs. J Immunol., 212, 2024
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1YN3
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![BU of 1yn3 by Molmil](/molmil-images/mine/1yn3) | Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens | Descriptor: | truncated cell surface protein map-w | Authors: | Geisbrecht, B.V, Hamaoka, B.Y, Perman, B, Zemla, A, Leahy, D.J. | Deposit date: | 2005-01-23 | Release date: | 2005-03-01 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | The Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens. J.Biol.Chem., 280, 2005
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1YN4
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![BU of 1yn4 by Molmil](/molmil-images/mine/1yn4) | Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens | Descriptor: | EapH1, ZINC ION | Authors: | Geisbrecht, B.V, Hamaoka, B.Y, Perman, B, Zemla, A, Leahy, D.J. | Deposit date: | 2005-01-23 | Release date: | 2005-03-01 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens. J.Biol.Chem., 280, 2005
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1YN5
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![BU of 1yn5 by Molmil](/molmil-images/mine/1yn5) | Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens | Descriptor: | EapH2 | Authors: | Geisbrecht, B.V, Hamaoka, B.Y, Perman, B, Zemla, A, Leahy, D.J. | Deposit date: | 2005-01-23 | Release date: | 2005-03-01 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens. J.Biol.Chem., 280, 2005
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3NMS
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![BU of 3nms by Molmil](/molmil-images/mine/3nms) | |
3OHX
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![BU of 3ohx by Molmil](/molmil-images/mine/3ohx) | |
3L3O
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![BU of 3l3o by Molmil](/molmil-images/mine/3l3o) | |
3KS2
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![BU of 3ks2 by Molmil](/molmil-images/mine/3ks2) | |
3L5N
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![BU of 3l5n by Molmil](/molmil-images/mine/3l5n) | |
7RMU
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![BU of 7rmu by Molmil](/molmil-images/mine/7rmu) | |
7S0R
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![BU of 7s0r by Molmil](/molmil-images/mine/7s0r) | |
3GT2
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![BU of 3gt2 by Molmil](/molmil-images/mine/3gt2) | Crystal Structure of the P60 Domain from M. avium paratuberculosis Antigen MAP1272c | Descriptor: | 1,2-ETHANEDIOL, Putative uncharacterized protein, SULFATE ION | Authors: | Ramyar, K.X, Lingle, C.K, McWhorter, W.J, Bouyain, S, Bannantine, J.P, Geisbrecht, B.V. | Deposit date: | 2009-03-27 | Release date: | 2010-04-07 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal Structures of Two P60-Family Antigens from Mycobacterium Avium Paratuberculosis To be Published
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1FCH
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![BU of 1fch by Molmil](/molmil-images/mine/1fch) | CRYSTAL STRUCTURE OF THE PTS1 COMPLEXED TO THE TPR REGION OF HUMAN PEX5 | Descriptor: | PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR, PTS1-CONTAINING PEPTIDE | Authors: | Gatto Jr, G.J, Geisbrecht, B.V, Gould, S.J, Berg, J.M. | Deposit date: | 2000-07-18 | Release date: | 2000-12-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Peroxisomal targeting signal-1 recognition by the TPR domains of human PEX5. Nat.Struct.Biol., 7, 2000
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2NOJ
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![BU of 2noj by Molmil](/molmil-images/mine/2noj) | Crystal structure of Ehp / C3d complex | Descriptor: | Complement C3, Efb homologous protein | Authors: | Hammel, M, Geisbrecht, B.V. | Deposit date: | 2006-10-25 | Release date: | 2007-08-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Characterization of Ehp, a Secreted Complement Inhibitory Protein from Staphylococcus aureus. J.Biol.Chem., 282, 2007
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5JXU
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![BU of 5jxu by Molmil](/molmil-images/mine/5jxu) | Structural basis for the catalytic activity of Thermomonospora curvata heme-containing DyP-type peroxidase. | Descriptor: | Dyp-type peroxidase family, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Ramyar, K.X, Carlson, E.A, Li, P, Geisbrecht, B.V. | Deposit date: | 2016-05-13 | Release date: | 2016-10-19 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.751 Å) | Cite: | Identification of Surface-Exposed Protein Radicals and A Substrate Oxidation Site in A-Class Dye-Decolorizing Peroxidase from Thermomonospora curvata. ACS Catal, 6, 2016
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4NZL
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![BU of 4nzl by Molmil](/molmil-images/mine/4nzl) | Extracellular proteins of Staphylococcus aureus inhibit the neutrophil serine proteases | Descriptor: | Neutrophil elastase, Uncharacterized protein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Stapels, D.A.C, von Koeckritz-Blickwede, M, Ramyar, K.X, Bischoff, M, Milder, F, Ruyken, M, Scheepmaker, L, McWhorter, W.J, Herrmann, M, van Kessel, K.P.M, Geisbrecht, B.V, Rooijakkers, S.H.M. | Deposit date: | 2013-12-12 | Release date: | 2014-08-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Staphylococcus aureus secretes a unique class of neutrophil serine protease inhibitors. Proc.Natl.Acad.Sci.USA, 111, 2014
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1SZH
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![BU of 1szh by Molmil](/molmil-images/mine/1szh) | Crystal Structure of C. elegans HER-1 | Descriptor: | ACETATE ION, Her-1 protein | Authors: | Hamaoka, B.Y, Dann III, C.E, Geisbrecht, B.V, Leahy, D.J. | Deposit date: | 2004-04-05 | Release date: | 2004-08-10 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of Caenorhabditis elegans HER-1 and characterization of the interaction between HER-1 and TRA-2A. Proc.Natl.Acad.Sci.USA, 101, 2004
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2HHI
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![BU of 2hhi by Molmil](/molmil-images/mine/2hhi) | The solution structure of antigen MPT64 from Mycobacterium tuberculosis defines a novel class of beta-grasp proteins | Descriptor: | Immunogenic protein MPT64 | Authors: | Wang, Z, Potter, B.M, Gray, A.M, Sacksteder, K.A, Geisbrecht, B.V, Laity, J.H. | Deposit date: | 2006-06-28 | Release date: | 2006-12-05 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | The Solution Structure of Antigen MPT64 from Mycobacterium tuberculosis Defines a New Family of Beta-Grasp Proteins. J.Mol.Biol., 366, 2007
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6D69
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![BU of 6d69 by Molmil](/molmil-images/mine/6d69) | |
2GOM
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![BU of 2gom by Molmil](/molmil-images/mine/2gom) | |
2GOX
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![BU of 2gox by Molmil](/molmil-images/mine/2gox) | Crystal structure of Efb-C / C3d Complex | Descriptor: | Complement C3, Fibrinogen-binding protein | Authors: | Hammel, M, Geisbrecht, B.V. | Deposit date: | 2006-04-14 | Release date: | 2007-03-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A structural basis for complement inhibition by Staphylococcus aureus. Nat.Immunol., 8, 2007
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8TE6
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![BU of 8te6 by Molmil](/molmil-images/mine/8te6) | |