8E5M
 
 | | Structure of ARG1 complex with pyrrolidine-based non-boronic acid inhibitor 6 | | Descriptor: | 1-{[(3S,4S)-3-({4-[2-(4-fluorobenzene-1-sulfonyl)ethyl]piperidin-1-yl}methyl)-4-(3-fluorophenyl)pyrrolidin-1-yl]methyl}cyclopentane-1-carboxylic acid, Arginase-1, MANGANESE (II) ION | | Authors: | Palte, R.L, Gathiaka, S. | | Deposit date: | 2022-08-22 | | Release date: | 2023-03-08 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.84 Å) | | Cite: | Discovery of non-boronic acid Arginase 1 inhibitors through virtual screening and biophysical methods.
Bioorg.Med.Chem.Lett., 84, 2023
|
|
8H64
 | |
8HYI
 | | Crystal structure of human P-cadherin MEC12 (X dimer) in complex with 2-(2-methyl-5-phenyl-1H-indole-3-yl)ethan-1-amine | | Descriptor: | 2-(2-methyl-5-phenyl-1H-indole-3-yl)ethan-1-amine, CALCIUM ION, Cadherin-3, ... | | Authors: | Senoo, A, Ito, S, Ueno, G, Nagatoishi, S, Tsumoto, K. | | Deposit date: | 2023-01-06 | | Release date: | 2023-08-30 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Modulation of a conformational ensemble by a small molecule that inhibits key protein-protein interactions involved in cell adhesion.
Protein Sci., 32, 2023
|
|
1F2R
 | | NMR STRUCTURE OF THE HETERODIMERIC COMPLEX BETWEEN CAD DOMAINS OF CAD AND ICAD | | Descriptor: | CASPASE-ACTIVATED DNASE, INHIBITOR OF CASPASE-ACTIVATED DNASE | | Authors: | Otomo, T, Sakahira, H, Uegaki, K, Nagata, S, Yamazaki, T. | | Deposit date: | 2000-05-29 | | Release date: | 2000-06-08 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structure of the heterodimeric complex between CAD domains of CAD and ICAD.
Nat.Struct.Biol., 7, 2000
|
|
2ZY6
 | | Crystal structure of a truncated tRNA, TPHE39A | | Descriptor: | CALCIUM ION, CHLORIDE ION, MAGNESIUM ION, ... | | Authors: | Tanaka, I, Yao, M, Tanaka, Y, Kitago, Y, Ymagata, S. | | Deposit date: | 2009-01-14 | | Release date: | 2009-06-30 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Deduced RNA binding mechanism of ThiI based on structural and binding analyses of a minimal RNA ligand
Rna, 15, 2009
|
|
2L8D
 | | Structure/function of the LBR Tudor domain | | Descriptor: | Lamin-B receptor | | Authors: | Liokatis, S, Edlich, C, Soupsana, K, Giannios, I, Sattler, M, Georgatos, S.D, Politou, A.S. | | Deposit date: | 2011-01-10 | | Release date: | 2011-11-09 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Solution structure and molecular interactions of lamin B receptor tudor domain.
J.Biol.Chem., 287, 2012
|
|
5SBI
 | |
5SBJ
 | |
3WII
 | | Crystal structure of the Fab fragment of B2212A, a murine monoclonal antibody specific for the third fibronectin domain (Fn3) of human ROBO1. | | Descriptor: | anti-human ROBO1 antibody B2212A Fab heavy chain, anti-human ROBO1 antibody B2212A Fab light chain | | Authors: | Nakayama, T, Mizohata, E, Yamashita, T, Nagatoishi, S, Nakakido, M, Iwanari, H, Mochizuki, Y, Kado, Y, Yokota, Y, Sato, R, Tsumoto, K, Fujitani, H, Kodama, T, Hamakubo, T, Inoue, T. | | Deposit date: | 2013-09-12 | | Release date: | 2015-01-21 | | Last modified: | 2017-11-22 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural features of interfacial tyrosine residue in ROBO1 fibronectin domain-antibody complex: Crystallographic, thermodynamic, and molecular dynamic analyses
Protein Sci., 24, 2015
|
|
8H63
 | | Crystal structure of Internalin A from Listeria monocytogenes with nanobody VHH10 bound | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ISOPROPYL ALCOHOL, ... | | Authors: | Caaveiro, J.M.M, Nagatoish, S, Tsumoto, K. | | Deposit date: | 2022-10-15 | | Release date: | 2023-10-04 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.53 Å) | | Cite: | Anti-InlA single-domain antibodies that inhibit the cell invasion of Listeria monocytogenes.
J.Biol.Chem., 299, 2023
|
|
8H62
 | | Crystal structure of Internalin A from Listeria monocytogenes with human E-cadherin EC12 | | Descriptor: | ACETATE ION, CALCIUM ION, Cadherin-1, ... | | Authors: | Caaveiro, J.M.M, Nagatoish, S, Tsumoto, K. | | Deposit date: | 2022-10-14 | | Release date: | 2023-10-04 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | Anti-InlA single-domain antibodies that inhibit the cell invasion of Listeria monocytogenes.
J.Biol.Chem., 299, 2023
|
|
8HLB
 | | Cryo-EM structure of biparatopic antibody Bp109-92 in complex with TNFR2 | | Descriptor: | TR109 heavy chain, TR109 light chain, TR92 heavy chain, ... | | Authors: | Akiba, H, Fujita, J, Ise, T, Nishiyama, K, Miyata, T, Kato, T, Namba, K, Ohno, H, Kamada, H, Nagata, S, Tsumoto, K. | | Deposit date: | 2022-11-29 | | Release date: | 2023-10-04 | | Method: | ELECTRON MICROSCOPY (3.63 Å) | | Cite: | Development of a 1:1-binding biparatopic anti-TNFR2 antagonist by reducing signaling activity through epitope selection.
Commun Biol, 6, 2023
|
|
6K91
 | | Pyridoxal Kinase from Leishmania donovani in complex with ADP and Pyridoxine | | Descriptor: | 4,5-bis(hydroxymethyl)-2-methyl-pyridin-3-ol, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... | | Authors: | Are, S, Gatreddi, S, Qureshi, I.A. | | Deposit date: | 2019-06-13 | | Release date: | 2020-03-25 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural attributes and substrate specificity of pyridoxal kinase from Leishmania donovani.
Int.J.Biol.Macromol., 152, 2020
|
|
6K8Z
 | | Pyridoxal Kinase from Leishmania donovani in complex with ADP | | Descriptor: | ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... | | Authors: | Are, S, Gatreddi, S, Qureshi, I.A. | | Deposit date: | 2019-06-13 | | Release date: | 2020-03-25 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural attributes and substrate specificity of pyridoxal kinase from Leishmania donovani.
Int.J.Biol.Macromol., 152, 2020
|
|
6K92
 | | Pyridoxal Kinase from Leishmania donovani in complex with ADP and Ginkgotoxin | | Descriptor: | 5-(hydroxymethyl)-4-(methoxymethyl)-2-methylpyridin-3-ol, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... | | Authors: | Are, S, Gatreddi, S, Qureshi, I.A. | | Deposit date: | 2019-06-13 | | Release date: | 2020-03-25 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structural attributes and substrate specificity of pyridoxal kinase from Leishmania donovani.
Int.J.Biol.Macromol., 152, 2020
|
|
6K90
 | | Pyridoxal Kinase from Leishmania donovani in complex with ADP and Pyridoxamine | | Descriptor: | 4-(AMINOMETHYL)-5-(HYDROXYMETHYL)-2-METHYLPYRIDIN-3-OL, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... | | Authors: | Are, S, Gatreddi, S, Qureshi, I.A. | | Deposit date: | 2019-06-13 | | Release date: | 2020-03-25 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural attributes and substrate specificity of pyridoxal kinase from Leishmania donovani.
Int.J.Biol.Macromol., 152, 2020
|
|
