8WOY
 
 | | Cryo-EM structure of SARS-CoV-2 Omicron BA.4/5 RBD in complex with rabbit ACE2 (local refinement) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, Spike protein S1, ... | | Authors: | Li, L.J, Shi, K.Y, Yu, G.H, Gao, G.F. | | Deposit date: | 2023-10-08 | | Release date: | 2023-12-13 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (3.14 Å) | | Cite: | Structural basis of increased binding affinities of spikes from SARS-CoV-2 Omicron variants to rabbit and hare ACE2s reveals the expanding host tendency.
Mbio, 15, 2024
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8WOZ
 | | Cryo-EM structure of SARS-CoV RBD in complex with rabbit ACE2 | | Descriptor: | Angiotensin-converting enzyme, Spike protein S1, ZINC ION | | Authors: | Li, L.J, Shi, K.Y, Yu, G.H, Gao, G.F. | | Deposit date: | 2023-10-08 | | Release date: | 2023-12-13 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (3.25 Å) | | Cite: | Structural basis of increased binding affinities of spikes from SARS-CoV-2 Omicron variants to rabbit and hare ACE2s reveals the expanding host tendency.
Mbio, 15, 2024
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8WOX
 | | Cryo-EM structure of SARS-CoV-2 prototype RBD in complex with rabbit ACE2 (local refinement) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, Spike protein S1, ... | | Authors: | Li, L.J, Shi, K.Y, Yu, G.H, Gao, G.F. | | Deposit date: | 2023-10-08 | | Release date: | 2023-12-13 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (2.75 Å) | | Cite: | Structural basis of increased binding affinities of spikes from SARS-CoV-2 Omicron variants to rabbit and hare ACE2s reveals the expanding host tendency.
Mbio, 15, 2024
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3HG1
 | | Germline-governed recognition of a cancer epitope by an immunodominant human T cell receptor | | Descriptor: | Beta-2-microglobulin, CANCER/MART-1, GLYCEROL, ... | | Authors: | Cole, D.K, Yuan, F, Rizkallah, P.J, Miles, J.J, Gostick, E, Price, D.A, Gao, G.F, Jakobsen, B.K, Sewell, A.K. | | Deposit date: | 2009-05-13 | | Release date: | 2009-07-28 | | Last modified: | 2014-04-09 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Germ line-governed recognition of a cancer epitope by an immunodominant human T-cell receptor.
J.Biol.Chem., 284, 2009
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3P2T
 | | Crystal Structure of Leukocyte Ig-like Receptor LILRB4 (ILT3/LIR-5/CD85k) | | Descriptor: | Leukocyte immunoglobulin-like receptor subfamily B member 4, SULFATE ION | | Authors: | Chen, Y, Nam, G, Cheng, H, Zhang, J.H, Willcox, B.E, Gao, G.F. | | Deposit date: | 2010-10-04 | | Release date: | 2011-03-30 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.699 Å) | | Cite: | Crystal structure of leukocyte Ig-like receptor LILRB4 (ILT3/LIR-5/CD85k): a myeloid inhibitory receptor involved in immune tolerance
J.Biol.Chem., 286, 2011
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3Q2C
 | | Binding properties to HLA class I molecules and the structure of the leukocyte Ig-like receptor A3 (LILRA3/ILT6/LIR4/CD85e) | | Descriptor: | Leukocyte immunoglobulin-like receptor subfamily A member 3 | | Authors: | Ryu, M, Chen, Y, Qi, J.X, Liu, J, Shi, Y, Cheng, H, Gao, G.F. | | Deposit date: | 2010-12-20 | | Release date: | 2011-07-13 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | LILRA3 binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1/LILRB2: structural evidence
Plos One, 6, 2011
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8X80
 | | Structure of leptin-LepR trimer with a small gap | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Leptin, ... | | Authors: | Xie, Y.F, Gao, G.F. | | Deposit date: | 2023-11-27 | | Release date: | 2024-08-07 | | Method: | ELECTRON MICROSCOPY (3.88 Å) | | Cite: | Structural plasticity of human leptin binding to its receptor LepR
Hlife, 1, 2023
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8XSF
 | | SARS-CoV-2 RBD + IMCAS-364 + hACE2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, IMCAS-364 H chain, ... | | Authors: | Tong, Z, Cui, Y, Xie, Y, Tong, J, Gao, G.F, Qi, J. | | Deposit date: | 2024-01-09 | | Release date: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (2.16 Å) | | Cite: | Deciphering a reliable synergistic bispecific strategy of rescuing antibodies for SARS-CoV-2 escape variants, including BA.2.86, EG.5.1, and JN.1.
Cell Rep, 43, 2024
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8XSI
 | | SARS-CoV-2 RBD + IMCAS-364 (Local Refinement) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, IMCAS-364 H chain, IMCAS-364 L chain, ... | | Authors: | Tong, Z, Cui, Y, Xie, Y, Tong, J, Gao, G.F, Qi, J. | | Deposit date: | 2024-01-09 | | Release date: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (2.1 Å) | | Cite: | Deciphering a reliable synergistic bispecific strategy of rescuing antibodies for SARS-CoV-2 escape variants, including BA.2.86, EG.5.1, and JN.1.
Cell Rep, 43, 2024
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8XSE
 | | SARS-CoV-2 RBD + IMCAS-123 + IMCAS-72 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, IMCAS-123 H chain, IMCAS-123 L chain, ... | | Authors: | Tong, Z, Cui, Y, Xie, Y, Tong, J, Gao, G.F, Qi, J. | | Deposit date: | 2024-01-09 | | Release date: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Deciphering a reliable synergistic bispecific strategy of rescuing antibodies for SARS-CoV-2 escape variants, including BA.2.86, EG.5.1, and JN.1.
Cell Rep, 43, 2024
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8XSJ
 | | SARS-CoV-2 Omicron BA.4 RBD + IMCAS-316 + ACE2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | | Authors: | Tong, Z, Cui, Y, Xie, Y, Tong, J, Gao, G.F, Qi, J. | | Deposit date: | 2024-01-09 | | Release date: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (2.61 Å) | | Cite: | Deciphering a reliable synergistic bispecific strategy of rescuing antibodies for SARS-CoV-2 escape variants, including BA.2.86, EG.5.1, and JN.1.
Cell Rep, 43, 2024
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8X81
 | | Structure of leptin-LepR trimer with a large gap | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Leptin, ... | | Authors: | Xie, Y.F, Gao, G.F. | | Deposit date: | 2023-11-27 | | Release date: | 2024-08-07 | | Method: | ELECTRON MICROSCOPY (3.77 Å) | | Cite: | Structural plasticity of human leptin binding to its receptor LepR
Hlife, 1, 2023
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8XSL
 | | SARS-CoV-2 spike + IMCAS-123 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IMCAS-123 heavy chain, ... | | Authors: | Tong, Z, Cui, Y, Xie, Y, Tong, J, Gao, G.F, Qi, J. | | Deposit date: | 2024-01-09 | | Release date: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Deciphering a reliable synergistic bispecific strategy of rescuing antibodies for SARS-CoV-2 escape variants, including BA.2.86, EG.5.1, and JN.1.
Cell Rep, 43, 2024
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8Y16
 | | Cryo-EM structure of SARS-CoV-2 Omicron JN.1 spike protein in complex with human ACE2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | | Authors: | Li, L.J, Gu, Y.H, Qi, J.X, Gao, G.F. | | Deposit date: | 2024-01-23 | | Release date: | 2024-07-03 | | Last modified: | 2024-08-21 | | Method: | ELECTRON MICROSCOPY (2.98 Å) | | Cite: | Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 32, 2024
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8XLV
 | | Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 spike protein(6P), 1-RBD-up state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | Authors: | Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F. | | Deposit date: | 2023-12-26 | | Release date: | 2024-07-03 | | Last modified: | 2024-08-21 | | Method: | ELECTRON MICROSCOPY (3.07 Å) | | Cite: | Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 32, 2024
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8Y5J
 | | Cryo-EM structure of SARS-CoV-2 Omicron JN.1 spike protein | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | Authors: | Li, L.J, Gu, Y.H, Qi, J.X, Gao, G.F. | | Deposit date: | 2024-01-31 | | Release date: | 2024-07-03 | | Last modified: | 2024-08-21 | | Method: | ELECTRON MICROSCOPY (2.94 Å) | | Cite: | Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 32, 2024
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8X85
 | | Structure of leptin-LepR dimer | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Leptin, Leptin receptor, ... | | Authors: | Xie, Y.F, Shang, G.J, Qi, J.X, Gao, G.F. | | Deposit date: | 2023-11-27 | | Release date: | 2024-08-07 | | Method: | ELECTRON MICROSCOPY (3.58 Å) | | Cite: | Structural plasticity of human leptin binding to its receptor LepR
Hlife, 1, 2023
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8XB8
 | | The structure of ASFV A137R | | Descriptor: | A137R | | Authors: | Li, C, Song, H, Gao, G.F. | | Deposit date: | 2023-12-06 | | Release date: | 2024-01-31 | | Last modified: | 2024-04-03 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | African swine fever virus A137R assembles into a dodecahedron cage.
J.Virol., 98, 2024
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8XMT
 | | Cryo-EM structure of SARS-CoV-2 Omicron EG.5.1 spike protein(6P), RBD-closed state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | Authors: | Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F. | | Deposit date: | 2023-12-28 | | Release date: | 2024-07-03 | | Last modified: | 2024-08-21 | | Method: | ELECTRON MICROSCOPY (3.31 Å) | | Cite: | Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 32, 2024
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8XN5
 | | Cryo-EM structure of SARS-CoV-2 Omicron EG.5.1 spike protein(6P) in complex with human ACE2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein, ... | | Authors: | Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F. | | Deposit date: | 2023-12-29 | | Release date: | 2024-07-03 | | Last modified: | 2024-08-21 | | Method: | ELECTRON MICROSCOPY (2.87 Å) | | Cite: | Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 32, 2024
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8XNK
 | | Cryo-EM structure of SARS-CoV-2 Omicron HV.1 spike protein(6P) in complex with human ACE2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein, ... | | Authors: | Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F. | | Deposit date: | 2023-12-30 | | Release date: | 2024-07-03 | | Last modified: | 2024-08-21 | | Method: | ELECTRON MICROSCOPY (2.78 Å) | | Cite: | Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 32, 2024
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8XMG
 | | Cryo-EM structure of SARS-CoV-2 Omicron HV.1 spike protein(6P), RBD-closed state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | Authors: | Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F. | | Deposit date: | 2023-12-27 | | Release date: | 2024-07-03 | | Last modified: | 2024-08-21 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 32, 2024
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8XN3
 | | SARS-CoV-2 Omicron HV.1 RBD in complex with human ACE2 (local refinement from the spike protein) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1, ... | | Authors: | Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F. | | Deposit date: | 2023-12-28 | | Release date: | 2024-07-03 | | Last modified: | 2024-08-21 | | Method: | ELECTRON MICROSCOPY (2.64 Å) | | Cite: | Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 32, 2024
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8XM5
 | | Cryo-EM structure of SARS-CoV-2 Omicron EG.5 spike protein(6P), RBD-closed state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | Authors: | Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F. | | Deposit date: | 2023-12-27 | | Release date: | 2024-07-03 | | Last modified: | 2024-08-21 | | Method: | ELECTRON MICROSCOPY (2.61 Å) | | Cite: | Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 32, 2024
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8XNF
 | | Cryo-EM structure of SARS-CoV-2 Omicron BA.2.86 spike protein(6P) in complex with human ACE2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | | Authors: | Li, L.J, Gu, Y.H, Shi, K.Y, Qi, J.X, Gao, G.F. | | Deposit date: | 2023-12-29 | | Release date: | 2024-07-03 | | Last modified: | 2024-08-21 | | Method: | ELECTRON MICROSCOPY (3.26 Å) | | Cite: | Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA.2.86, JN.1, EG.5, EG.5.1, and HV.1 sub-variants.
Structure, 32, 2024
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