5LJ5
 
 | | Overall structure of the yeast spliceosome immediately after branching. | | 分子名称: | CWC15, CWC22, Exon 1 (5' exon) of UBC4 pre-mRNA, ... | | 著者 | Galej, W.P, Wilkinson, M.F, Fica, S.M, Oubridge, C, Newman, A.J, Nagai, K. | | 登録日 | 2016-07-17 | | 公開日 | 2016-08-31 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Cryo-EM structure of the spliceosome immediately after branching.
Nature, 537, 2016
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5LJ3
 | | Structure of the core of the yeast spliceosome immediately after branching | | 分子名称: | CEF1, CLF1, CWC15, ... | | 著者 | Galej, W.P, Wilkinson, M.F, Fica, S.M, Oubridge, C, Newman, A.J, Nagai, K. | | 登録日 | 2016-07-17 | | 公開日 | 2016-08-03 | | 最終更新日 | 2019-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Cryo-EM structure of the spliceosome immediately after branching.
Nature, 537, 2016
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4I43
 | | Crystal structure of Prp8:Aar2 complex | | 分子名称: | A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8 | | 著者 | Galej, W.P, Oubridge, C, Newman, A.J, Nagai, K. | | 登録日 | 2012-11-27 | | 公開日 | 2013-01-23 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of Prp8 reveals active site cavity of the spliceosome.
Nature, 493, 2013
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3ZEF
 | | Crystal structure of Prp8:Aar2 complex: second crystal form at 3.1 Angstrom resolution | | 分子名称: | A1 CISTRON-SPLICING FACTOR AAR2, PRE-MRNA-SPLICING FACTOR 8 | | 著者 | Galej, W.P, Oubridge, C, Newman, A.J, Nagai, K. | | 登録日 | 2012-12-05 | | 公開日 | 2013-01-30 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Crystal Structure of Prp8 Reveals Active Site Cavity of the Spliceosome
Nature, 493, 2013
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6EXN
 | | Post-catalytic P complex spliceosome with 3' splice site docked | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Intron lariat: UBC4 RNA, ... | | 著者 | Wilkinson, M.E, Fica, S.M, Galej, W.P, Norman, C.M, Newman, A.J, Nagai, K. | | 登録日 | 2017-11-08 | | 公開日 | 2018-01-17 | | 最終更新日 | 2020-10-07 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Postcatalytic spliceosome structure reveals mechanism of 3'-splice site selection.
Science, 358, 2017
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6S5T
 | | Legionella pneumophila SidJ-Human calmodulin complex | | 分子名称: | Calmodulin-2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SidJ | | 著者 | Bhogaraju, S, Galej, W.P, Pfleiderer, M.M, Adams, M. | | 登録日 | 2019-07-02 | | 公開日 | 2019-07-24 | | 最終更新日 | 2019-08-28 | | 実験手法 | ELECTRON MICROSCOPY (4.15 Å) | | 主引用文献 | Inhibition of bacterial ubiquitin ligases by SidJ-calmodulin catalysed glutamylation.
Nature, 572, 2019
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7Q4O
 | | Substrate-bound A-like U2 snRNP | | 分子名称: | BPS oligo, PHD finger-like domain-containing protein 5A, Splicing factor 3A subunit 2, ... | | 著者 | Tholen, J, Galej, W.P. | | 登録日 | 2021-11-01 | | 公開日 | 2022-03-30 | | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | | 主引用文献 | Structural basis of branch site recognition by the human spliceosome.
Science, 375, 2022
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7Q4P
 | | U2 snRNP after ATP-dependent remodelling | | 分子名称: | PHD finger-like domain-containing protein 5A, Splicing factor 3A subunit 2, Splicing factor 3A subunit 3, ... | | 著者 | Tholen, J, Galej, W.P. | | 登録日 | 2021-11-01 | | 公開日 | 2022-03-30 | | 最終更新日 | 2022-04-06 | | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | | 主引用文献 | Structural basis of branch site recognition by the human spliceosome.
Science, 375, 2022
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7Q3L
 | | Human 17S U2 snRNP 5' domain | | 分子名称: | HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, Probable ATP-dependent RNA helicase DDX46, ... | | 著者 | Tholen, J, Galej, W.P. | | 登録日 | 2021-10-28 | | 公開日 | 2022-03-30 | | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | | 主引用文献 | Structural basis of branch site recognition by the human spliceosome.
Science, 375, 2022
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8Q91
 | | Structure of the human 20S U5 snRNP core | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, CD2 antigen cytoplasmic tail-binding protein 2, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Schneider, S, Galej, W.P. | | 登録日 | 2023-08-19 | | 公開日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structure of the human 20S U5 snRNP.
Nat.Struct.Mol.Biol., 2024
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8RC0
 | | Structure of the human 20S U5 snRNP | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, CD2 antigen cytoplasmic tail-binding protein 2, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Schneider, S, Galej, W.P. | | 登録日 | 2023-12-05 | | 公開日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure of the human 20S U5 snRNP.
Nat.Struct.Mol.Biol., 2024
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5GAM
 | | Foot region of the yeast spliceosomal U4/U6.U5 tri-snRNP | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, Pre-mRNA-splicing factor 8, Pre-mRNA-splicing factor SNU114, ... | | 著者 | Nguyen, T.H.D, Galej, W.P, Bai, X.C, Oubridge, C, Scheres, S.H.W, Newman, A.J, Nagai, K. | | 登録日 | 2015-12-15 | | 公開日 | 2016-02-03 | | 最終更新日 | 2019-10-02 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 Angstrom resolution
Nature, 530, 2016
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5GAN
 | | The overall structure of the yeast spliceosomal U4/U6.U5 tri-snRNP at 3.7 Angstrom | | 分子名称: | 13 kDa ribonucleoprotein-associated protein, GUANOSINE-5'-TRIPHOSPHATE, Pre-mRNA-processing factor 31, ... | | 著者 | Nguyen, T.H.D, Galej, W.P, Bai, X.C, Oubridge, C, Scheres, S.H.W, Newman, A.J, Nagai, K. | | 登録日 | 2015-12-15 | | 公開日 | 2016-01-27 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution.
Nature, 530, 2016
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5GAO
 | | Head region of the yeast spliceosomal U4/U6.U5 tri-snRNP | | 分子名称: | Pre-mRNA-splicing factor 8, Pre-mRNA-splicing helicase BRR2, Saccharomyces cerevisiae strain UOA_M2 chromosome 5 sequence, ... | | 著者 | Nguyen, T.H.D, Galej, W.P, Bai, X.C, Oubridge, C, Scheres, S.H.W, Newman, A.J, Nagai, K. | | 登録日 | 2015-12-15 | | 公開日 | 2016-01-27 | | 最終更新日 | 2019-10-02 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution.
Nature, 530, 2016
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8Q4L
 | | GBP1 bound by 14-3-3sigma | | 分子名称: | 14-3-3 protein sigma, Guanylate-binding protein 1 | | 著者 | Pfleiderer, M.M, Liu, X, Fisch, D, Anastasakou, E, Frickel, E.M, Galej, W.P. | | 登録日 | 2023-08-07 | | 公開日 | 2023-10-11 | | 最終更新日 | 2023-10-18 | | 実験手法 | ELECTRON MICROSCOPY (5.12 Å) | | 主引用文献 | PIM1 controls GBP1 activity to limit self-damage and to guard against pathogen infection.
Science, 382, 2023
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7B9V
 | | Yeast C complex spliceosome at 2.8 Angstrom resolution with Prp18/Slu7 bound | | 分子名称: | 5' exon of UBC4 mRNA, BJ4_G0027490.mRNA.1.CDS.1, BJ4_G0054360.mRNA.1.CDS.1, ... | | 著者 | Wilkinson, M.E, Fica, S.M, Galej, W.P, Nagai, K. | | 登録日 | 2020-12-14 | | 公開日 | 2021-03-10 | | 最終更新日 | 2021-04-14 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural basis for conformational equilibrium of the catalytic spliceosome.
Mol.Cell, 81, 2021
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7BFP
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7BFQ
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5GAP
 | | Body region of the U4/U6.U5 tri-snRNP | | 分子名称: | 13 kDa ribonucleoprotein-associated protein, Pre-mRNA-processing factor 31, Pre-mRNA-splicing factor 6, ... | | 著者 | Nguyen, T.H.D, Galej, W.P, Oubridge, C, Bai, X.C, Newman, A, Scheres, S, Nagai, K. | | 登録日 | 2015-12-15 | | 公開日 | 2016-01-27 | | 最終更新日 | 2019-10-02 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution.
Nature, 530, 2016
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5MPS
 | | Structure of a spliceosome remodeled for exon ligation | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Fica, S.M, Oubridge, C, Galej, W.P, Wilkinson, M.E, Newman, A.J, Bai, X.-C, Nagai, K. | | 登録日 | 2016-12-18 | | 公開日 | 2017-01-18 | | 最終更新日 | 2020-10-07 | | 実験手法 | ELECTRON MICROSCOPY (3.85 Å) | | 主引用文献 | Structure of a spliceosome remodelled for exon ligation.
Nature, 542, 2017
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5MQ0
 | | Structure of a spliceosome remodeled for exon ligation | | 分子名称: | 3'-EXON OF UBC4 PRE-MRNA, BOUND BY PRP22 HELICASE, 5'-EXON OF UBC4 PRE-MRNA, ... | | 著者 | Fica, S.M, Oubridge, C, Galej, W.P, Wilkinson, M.E, Newman, A.J, Bai, X.-C, Nagai, K. | | 登録日 | 2016-12-19 | | 公開日 | 2017-01-18 | | 最終更新日 | 2020-10-07 | | 実験手法 | ELECTRON MICROSCOPY (4.17 Å) | | 主引用文献 | Structure of a spliceosome remodelled for exon ligation.
Nature, 542, 2017
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