1ZJK
 
 | | Crystal structure of the zymogen catalytic region of human MASP-2 | | 分子名称: | Mannan-binding lectin serine protease 2 | | 著者 | Gal, P, Harmat, V, Kocsis, A, Bian, T, Barna, L, Ambrus, G, Vegh, B, Balczer, J, Sim, R.B, Naray-Szabo, G, Zavodszky, P. | | 登録日 | 2005-04-29 | | 公開日 | 2005-07-26 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | A True Autoactivating Enzyme: Structural insight into mannose-binding lectin-associated serine protease-2 activations
J.Biol.Chem., 280, 2005
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3ZKE
 | | Structure of LC8 in complex with Nek9 peptide | | 分子名称: | DYNEIN LIGHT CHAIN 1, CYTOPLASMIC, NEK9 PROTEIN | | 著者 | Gallego, P, Velazquez-Campoy, A, Regue, L, Roig, J, Reverter, D. | | 登録日 | 2013-01-22 | | 公開日 | 2013-03-20 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural Analysis of the Regulation of the Dynll/Lc8 Binding to Nek9 by Phosphorylation
J.Biol.Chem., 288, 2013
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3ZKF
 | | Structure of LC8 in complex with Nek9 phosphopeptide | | 分子名称: | DYNEIN LIGHT CHAIN 1, CYTOPLASMIC, NEK9 PROTEIN | | 著者 | Gallego, P, Velazquez-Campoy, A, Regue, L, Roig, J, Reverter, D. | | 登録日 | 2013-01-22 | | 公開日 | 2013-03-20 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural Analysis of the Regulation of the Dynll/Lc8 Binding to Nek9 by Phosphorylation
J.Biol.Chem., 288, 2013
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7QCL
 | | Structure of the MUCIN-2 Cterminal domains | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Mucin-2, ... | | 著者 | Gallego, P, Hansson, G.C. | | 登録日 | 2021-11-24 | | 公開日 | 2023-03-08 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.36 Å) | | 主引用文献 | The intestinal MUC2 mucin C-terminus is stabilized by an extra disulfide bond in comparison to von Willebrand factor and other gel-forming mucins.
Nat Commun, 14, 2023
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7QCU
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7QCN
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5OM9
 | | Crystal structure of the human CARBOXYPEPTIDASE A1 in complex with a thiirane mechanism-based inhibitor | | 分子名称: | (2~{R})-4-methyl-2-[(1~{S})-1-sulfanylethyl]pentanoic acid, Carboxypeptidase A1, ZINC ION | | 著者 | Gallego, P, Granados, C, Fernandez, D, Pallares, I, Covaleda, G, Aviles, F.X, Vendrell, J, Reverter, D. | | 登録日 | 2017-07-28 | | 公開日 | 2017-08-09 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Discovery of Mechanism-Based Inactivators for Human Pancreatic Carboxypeptidase A from a Focused Synthetic Library.
ACS Med Chem Lett, 8, 2017
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3NS7
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6I6Z
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4UEE
 | | Crystal structure of the human CARBOXYPEPTIDASE A1 in complex with the PHOSPHINIC INHIBITOR Acetyl-Leu-Ala-Y(PO2CH2)-homoPhe-OH | | 分子名称: | (2S)-2-{[(R)-{(1R)-1-[(N-acetyl-L-leucyl)amino]ethyl}(hydroxy)phosphoryl]methyl}-4-phenylbutanoic acid, CARBOXYPEPTIDASE A1, ZINC ION | | 著者 | Gallego, P, Covaleda, G, Costenaro, L, Devel, L, Dive, V, Aviles, F.X, Reverter, D. | | 登録日 | 2014-12-17 | | 公開日 | 2016-01-20 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | Crystal Structure of the Human Carboxypeptidase A1 in Complex with Phosphinic Inhibitors
To be Published
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4UEZ
 | | Crystal structure of the human CARBOXYPEPTIDASE A1 in complex with the PHOSPHINIC INHIBITOR Acetyl-Leu-Phe-Y(PO2CH2)-Phe-OH | | 分子名称: | (2S)-3-[(R)-{(1R)-1-[(N-acetyl-L-leucyl)amino]-2-phenylethyl}(hydroxy)phosphoryl]-2-benzylpropanoic acid, HUMAN CARBOXYPEPTIDASE A1, ZINC ION | | 著者 | Gallego, P, Covaleda, G, Costenaro, L, Devel, L, Dive, V, Aviles, F.X, Reverter, D. | | 登録日 | 2014-12-22 | | 公開日 | 2016-01-20 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Crystal Structure of the Human Carboxypeptidase A1 in Complex with Phosphinic Inhibitors
To be Published
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6SXJ
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6XXQ
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6XZ0
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6FZB
 | | AadA in complex with ATP, magnesium and streptomycin | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Kanchugal P, S, Selmer, M. | | 登録日 | 2018-03-14 | | 公開日 | 2018-06-13 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structural mechanism of AadA, a dual-specificity aminoglycoside adenylyltransferase fromSalmonella enterica.
J. Biol. Chem., 293, 2018
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5AQ0
 | | The structure of the Transthyretin-like domain of the first catalytic domain of the HUMAN Carboxypeptidase D | | 分子名称: | CARBOXYPEPTIDASE D, GLYCEROL | | 著者 | Gallego, P, Garcia-Pardo, J, Lorenzo, J, Aviles, F.X, Ventura, S, Reverter, D. | | 登録日 | 2015-09-18 | | 公開日 | 2016-09-28 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (0.95 Å) | | 主引用文献 | The Structure of the Ttldomain of the Human Carboxypeptidase D
To be Published
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5AEK
 | | Crystal structure of the human SENP2 C548S in complex with the human SUMO1 K48M F66W | | 分子名称: | SENTRIN-SPECIFIC PROTEASE 2, SMALL UBIQUITIN-RELATED MODIFIER 1 | | 著者 | Gallego, P, Grana-Montes, R, Espargaro, A, Castillo, V, Torrent, J, Lange, R, Papaleo, E, Lindorff-Larsend, K, Ventura, S, Reverter, D. | | 登録日 | 2014-12-23 | | 公開日 | 2016-01-20 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Stepping Back and Forward on Sumo Folding Evolution
To be Published
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3OWU
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3OX9
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3OWS
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3OXA
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5LQG
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5LQH
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5FW6
 | | Structure of human transthyretin mutant A108V | | 分子名称: | TRANSTHYRETIN | | 著者 | Gallego, P, Varejao, N, Santanna, R, Saraiva, M.J, Ventura, S, Reverter, D. | | 登録日 | 2016-02-12 | | 公開日 | 2017-03-08 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Cavity filling mutations at the thyroxine-binding site dramatically increase transthyretin stability and prevent its aggregation.
Sci Rep, 7, 2017
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3OWY
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